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What is malignant fibrous histiocytoma?
A malignant fibrous histiocytoma is a type of cancerous tumor that can start in either bone or, most often, in the soft tissues that connect, support or surround organs and other body parts. It’s a painless mass that most often turns up in the extremities, although it can occur anywhere in the body. It most commonly spreads (metastasizes) to the lungs, but can also invade the lymph nodes and bone.
What causes malignant fibrous histiocytoma?
The exact cause of malignant fibrous histiocytoma is not entirely understood, however, studies have indicated that genetics may play a role. In addition:
Is malignant fibrous histiocytoma common?
While it’s among the most common types of soft tissue tumors found in adults, it is rarely found in children. It makes up only a tiny percentage of all soft tissue sarcomas, which as a group account for only 1 percent of new cancer cases in children each year.
What are the symptoms of malignant fibrous histiocytoma?
Because soft tissue sarcomas affect tissue that is elastic and easily moved, a tumor may exist for a long time before being discovered, growing large and pushing aside surrounding tissue. Symptoms vary greatly with the size, location and spread of the tumor, but may include:
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”