Lyme Disease Pediatric Research and Clinical Trials

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Contact the Division of Infectious Diseases

Boston Children’s Hospital is home to the world’s largest research program at a pediatric institution, and we’re known for pioneering new treatments. A large part of our success comes from our commitment to research—and to advancing the frontiers of what’s possible through our innovative approach.

Research in the Division of Infectious Diseases includes both basic investigation and clinical research. The bench research in the division has the broad objective of understanding basic mechanisms of microbial pathogenesis and the related host responses that mediate susceptibility to infection, host injury and protective immunity. Investigation targets viral, bacterial and fungal pathogens of major significance in community acquired infections in the United States, in infections of immunocompromised hosts, and in global public health. Current projects include:

  • pathogen-host signaling in streptococcal infection
  • innate immunity in bacterial infection
  • regulation of bacterial gene expression
  • HIV pathogenesis, immune response and vaccine development
  • regulation of morphogenesis in Candida albicans

Clinical research is focused in two broad areas: clinical trials in pediatric HIV and clinical epidemiology/clinical decision-making.

We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

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