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Boston Children's has launched the world's 1st program dedicated to offering hand transplants to children who qualify.
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Much of today’s research on attention-deficit/hyperactivity disorder (ADHD) focuses on genetics. Here at Boston Children’s Hospital, our researchers are also looking closely at the structural and functional differences between the brains of children and adults with ADHD and the brains of people not affected by the disorder.
In addition, Boston Children’s physicians and scientists are engaged in several innovative studies designed to increase understanding of how ADHD affects children, and how best to diagnose and treat it.
However, since the pen-and-paper process does not always (or entirely) capture the information necessary for monitoring children with ADHD, Boston Children’s has helped design a web-based data entry tool for parents—one that regularly updates doctors about a child’s ADHD.
This online program guides parents through each step of reporting the relevant information, with a built-in mechanism to ensure that questions aren't skipped over. Eugenia Chan, MD, MPH, an ADHD specialist in Boston Children’s Developmental Medicine Center, helped develop the tool. She hopes that teachers will also use it to provide input on a child's behavior at school.
Over the course of this 15-year study, Barbaresi and his colleagues have followed approximately 700 children—more than 200 of whom were diagnosed with and treated for ADHD as kids—from early childhood through adulthood.
In an attempt to understand how ADHD affects different facets of life, the researchers have compared the lives of people who had ADHD as children to the lives of those who did not. These comparisons cover a number of areas, including:
Barbaresi and his colleagues are now analyzing the data from this landmark study.
Learn more about research projects at Boston Children’s.
Last month, the American Academy of Pediatrics released new guidelines on attention-deficit hyperactivity disorder (ADHD), lowering the minimum age at which physicians should consider drug treatment from 6 years to 4 years.
But here’s the problem. “Current behavioral criteria for ADHD are most effective only after age 8 or 9,” says Margaret Sheridan of the Laboratories of Cognitive Neuroscience at Boston Children’s Hospital. “If you use them at age 3 to 6, then you’re wrong about half the time, and the child will stop meeting the criteria by age 8.”
Sheridan wants to avoid these problems by finding an objective, measurable pattern of brain activity that reliably predicts ADHD in children as young as 3. Does that difference persist over time? Does it correlate with behavioral measures? Does treatment change the brain activity?
To date, she’s enrolled about 40 children in a study that is measuring both EEG activity and metabolic activity on functional MRI (fMRI) scans in children 3 to 7 –both typical children and children meeting research criteria for ADHD. (The fMRI studies start at age 5, when most children can hold still in the scanner). The study will ultimately enroll 200 children (for information, and to enroll a child, call Kelly Khem at 857-218-5220 or email firstname.lastname@example.org).
Read more about the study.
Boston Children’s is known worldwide for pioneering some of the most effective diagnostic tools, therapies and preventive approaches in pediatric medicine. A significant part of our success comes from our commitment to research—and to advancing the frontiers of health care by conducting clinical trials.
Boston Children’s coordinates hundreds of clinical trials at any given time. Clinical trials are studies that may involve:
Boston Children’s is involved in several multi-site clinical trials and studies focusing on pediatric neurology, psychiatry and developmental medicine. While children must meet strict criteria in order to be eligible for a clinical trial, your child may be a candidate for participation in a study. Before considering this option, you should be sure to:
Taking part in a clinical trial at Boston Children’s is entirely voluntary. Our team will be sure to fully address any questions you may have, and you may remove your child from any medical study at any time.
Search current and upcoming clinical trials at Boston Children’s.
Search the National Institute of Health’s list of clinical trials taking place around the world.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”