Allergies Pediatric Research and Clinical Trials

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Boston Children’s Hospital's Allergy Program develops treatments informed by our research. Children’s is home to the world’s most extensive research enterprise at a pediatric hospital.

We’re known for our science- driven approach – we have the world’s most extensive research enterprise located in a hospital, and we’ve partnered with a number of top biotech and health care organizations. But our physicians never forget your child is a child, and not just another patient.

Boston Children’s is science-driven, but always patient-centered.

Research: One EpiPen may not be enough

Connecting research directly with patients, Boston Children’s and Massachusetts General Hospital found that children with food allergies may need to carry more than one EpiPen. The six-year study (Pediatrics, April) involving 1,255 children who visited the emergency room for food-related reactions found that 12 percent needed a second dose of epinephrine. Over half of the children had anaphylaxis, a dangerous reaction to an allergen. Susan Rudders, MD of Boston Children’s Division of Allergy and Immunology says, "Until we're able to clearly define risk factors for the most severe reactions, it may be safest to have all children at risk for food-related anaphylaxis carry two doses of epinephrine."

Asthma Research

The Asthma Clinical Research Center at Boston Children’s Hospital conducts numerous asthma research studies for all ages. For more information on current studies, please visit the links below.

If you or your child is interested in participating, please email: or call 857-218-5336

Allergy Researchers

Research is a priority at the Allergy Program, crucial to developing new testing and treatment approaches.  The team of allergy researchers include:

Dr. Raif Geha

  • basic science atopic dermatitis and allergy research

Dr. Lynda Schneider

  • clinical research on atopic dermatitis and food allergy

Dr. Dale Umetsu

  • clinical and basic science research on food allergy
  • basic science research on asthma

Dr. Talal Chatila

  • basic science food allergy research

Dr. Wanda Phipatanukal 

  • asthma
  • environmental allergens
  • food allergens in the environment
  • food allergy

Dr. Rima Rachid

  • food allergy research

Dr. John Lee

  • eosinophilic esophagititis research

Ari Fried

  • eosinophilic esophagititis research

Dr. William Sheehan

  • food allergy, asthma research

Dr. Lisa Stutius

  • food allergy research

Dr. Anahita Dioun

  • drug allergy research

Neither Boston Children’s Hospital or the Allergy Program at Boston Children’s unreservedly endorses the information found at other websites mentioned on our Web pages.

Oettgen Laboratory
Hans Oettgen, MD, PhD, is leading the Oettgen Laboratory in researching the regulation of immune responses by IgE antibodies, immunobiology of eczema vaccinatum and basophils in early responses to allergens. Currently, they are researching the effects of IgE levels on the growth and function of mast cells of the lungs and intestine. Read more about the Oettgen Laboratory.


Boston Children’s is so much more than a hospital—it’s a community of researchers, clinicians, administrators, support staff, innovators, teachers, patients and families, all working together to make the impossible possible. ”
- Sandra L. Fenwick, President and CEO

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