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Base Editing Leaves Patient Feeling More Than Fine

Read more: "A sickle cell first: Base editing, a new form of gene therapy, leaves patient feeling ‘more than fine.' "

Base Editing Leaves Patient Feeling More Than Fine BOSTON, MA [Dec. 7, 2024] — Though he doesn’t remember it, Branden Baptiste had his first sickle cell crisis at age 2. Through elementary school, he was in and out of the hospital with pain episodes, not …
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Model Enables Study of Age-Specific Responses to COVID mRNA Vaccines in a Dish

Read more: "Model enables study of age-specific responses to COVID mRNA vaccines in a dish."

Model Enables Study of Age-Specific Responses to COVID mRNA Vaccines in a Dish BOSTON, MA [Dec. 12, 2024] — mRNA vaccines clearly saved lives during the COVID-19 pandemic, but several studies suggest that older people had a somewhat reduced immune …
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Changing Lives Through Genetics: Children’s Rare Disease Collaborative

Read more: "Changing lives through genetics: The Children’s Rare Disease Collaborative."

Changing Lives Through Genetics: Children’s Rare Disease Collaborative BOSTON, MA [Dec. 14, 2024] — A 14-year-old girl was having back pain after a car accident and visited an orthopedic clinic at Boston Children’s Hospital. In the course of her care, she …
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Earlier Detection of a Malignancy in Neurofibromatosis Type 1

Read more: "Earlier detection of a malignancy in neurofibromatosis type 1 (NF1)."

Earlier Detection of a Malignancy in Neurofibromatosis Type 1 Study uncovers genetic markers for the evolution of malignant peripheral nerve sheath tumors (MPNSTs) that can help predict prognosis BOSTON, MA [Jan. 4, 2023] —  Neurofibromatosis type 1 (NF1) …
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Boston Children’s Ramps Up Single-Cell Discovery as Powerful Lens on Disease

Read more: "Boston Children’s ramps up single-cell discovery as a powerful lens on disease."

Boston Children’s Ramps Up Single-Cell Discovery as Powerful Lens on Disease $10 million grant will support collaborations across the hospital to create a curated pediatric ‘cell atlas’ to identify disease origins and effective treatments BOSTON, MA [Jan. …
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A New Immune Pathway Sheds Light on ALS

Read more: "A new immune pathway sheds light on ALS."

A New Immune Pathway Sheds Light on ALS Study suggests that inflammatory proteins involved in the innate immune system cause damage to neurons and play a role in neurodegenerative diseases BOSTON, MA [March 13, 2023] — While drugs are on the market to …
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Immune Development in Early Life (IDEAL) Study

Read more: "Immune Development in Early Life (IDEAL) study to identify new approaches for predicting and preventing childhood disease."

Immune Development in Early Life (IDEAL) Study New international project applies systems biology to discover ways to increase infant vaccine responsiveness and decrease childhood respiratory disease, including asthma BOSTON, MA [March 29, 2023] — …
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BMI and the Adolescent Brain: A Concerning Association

Read more: "BMI and the adolescent brain: A concerning association."

BMI and the Adolescent Brain: A Concerning Association Study finds that preteens with excess BMI have notable differences in cognitive performance, brain structures, and brain circuitry BOSTON, MA [April 26, 2023] — Obesity is a growing epidemic in …
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Boston Children’s to Help Lead Research in NSF AI Institute for Societal Decision Making

Read more: "Boston Children’s Hospital to help lead research in NSF AI Institute for Societal Decision Making."

Boston Children’s to Help Lead Research in NSF AI Institute for Societal Decision Making $20 million collaboration brings together AI researchers and social scientists to develop tools for societal challenges BOSTON, MA [May 5, 2023] — Artificial …