Current Environment:

Summary

The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to noxious stimulation.

Conditions

Anesthesia, Pain

Recruitment Status

Recruiting

Eligibility Criteria

Inclusion Criteria:

12-30 years of age
Structurally normal heart
Right-handed
English-speaking

Exclusion Criteria:

Unable to cooperate or understand the study
Neurologic disease
Diabetes mellitus
Syndrome of greater than minor severity.
Smoker
Scalp or hair does not permit sufficient optical light detection
Unable to keep his/her head still for a period of 200 consecutive seconds

Intervention

Intervention Type

Intervention Name

Drug

Remifentanil

Drug

Normal saline

Phase

Not Applicable

Gender

All

Minimum Age

12 Years

Maximum Age

30 Years

Download Date

January 7, 2021

Principal Investigator

Barry Kussman

Primary Contact Information

Rachel S Bernier, MPH

857-218-5348

rachel.bernier@childrens.harvard.edu

For more information on this trial, visit clinicaltrials.gov.

Contact

For more information and to contact the study team: