Summary

The primary aim is to utilize near-infrared spectroscopy (NIRS) in patients under general anesthesia to measure changes in brain blood flow in the bilateral somatosensory cortices and the prefrontal cortices in response to noxious stimulation.

Conditions

  • Anesthesia
  • Pain

Recruitment Status

UNKNOWN

Eligibility Criteria

Inclusion Criteria:

* 12-30 years of age
* Structurally normal heart
* Right-handed
* English-speaking

Exclusion Criteria:

* Unable to cooperate or understand the study
* Neurologic disease
* Diabetes mellitus
* Syndrome of greater than minor severity.
* Smoker
* Scalp or hair does not permit sufficient optical light detection
* Unable to keep his/her head still for a period of 200 consecutive seconds

Phase

NA

Gender

ALL

Min Age

12 Years

Max Age

30 Years

Download Date

2021-01-07

Principal Investigator

N/A

Primary Contact Information

Rachel S Bernier, MPH

857-218-5348

rachel.bernier@childrens.harvard.edu

Intervention

Intervention Type

DRUG

DRUG

Intervention Name

Remifentanil

Normal saline

Contact

For more information and to contact the study team:

Assessing the Cortical Response to Noxious and Auditory Stimuli Using Near Infrared Spectroscopy in Subjects Under General Anesthesia NCT02703090 Rachel S Bernier, MPH 857-218-5348 rachel.bernier@childrens.harvard.edu