Undergraduate Degree

  • University of Pennsylvania , 1997 , Philadelphia , PA

Medical School

  • University of Massachusetts Medical School , 2004 , Worcester , MA


  • Yale New Haven Children's Hospital , 2004 , New Haven , CT


  • Yale New Haven Children's Hospital , 2007 , New Haven , CT


Respiratory Diseases
  • Boston Children's Hospital , 2007 , Boston , MA


Dr. Gaffin serves as an expert for the Department of Medicine for Boston Children's Hospital Precision Medicine Service. For more information about the Precision Medicine Service please visit


  • American Board of Pediatrics, Pediatric Pulmonology


Publications powered by Harvard Catalyst Profiles

  1. Effect of School Integrated Pest Management or Classroom Air Filter Purifiers on Asthma Symptoms in Students With Active Asthma: A Randomized Clinical Trial. JAMA. 2021 09 07; 326(9):839-850. View abstract
  2. Reconstructing Phenotypes in Recurrent Severe Wheeze in Young Children. Am J Respir Crit Care Med. 2021 09 01; 204(5):495-496. View abstract
  3. Thoracic Multidetector Computed Tomography Findings of Dedicator of Cytokinesis 8 Deficiency in Children. J Thorac Imaging. 2021 Sep 01; 36(5):304-309. View abstract
  4. Predictors of successful mouse allergen reduction in inner-city homes of children with asthma. J Allergy Clin Immunol Pract. 2021 Jul 12. View abstract
  5. Development and Validation of the Asthma Exacerbation Risk Score Using Claims Data. Acad Pediatr. 2021 Jul 10. View abstract
  6. Associations of Snoring and Asthma Morbidity in the School Inner-City Asthma Study. J Allergy Clin Immunol Pract. 2021 Oct; 9(10):3679-3685.e1. View abstract
  7. Air quality, Environment and Respiratory Outcomes in Bronchopulmonary Dysplasia, the AERO-BPD cohort study: design and adaptation during the SARS-CoV-2 pandemic. BMJ Open Respir Res. 2021 06; 8(1). View abstract
  8. Lung function trajectories in children with post-prematurity respiratory disease: identifying risk factors for abnormal growth. Respir Res. 2021 May 10; 22(1):143. View abstract
  9. Impact of the COVID-19 Pandemic on Pediatric Emergency Department Use for Asthma. Ann Am Thorac Soc. 2021 04; 18(4):717-719. View abstract
  10. Responsiveness to Parenteral Corticosteroids and Lung Function Trajectory in Adults with Moderate-to-Severe Asthma. Am J Respir Crit Care Med. 2021 04 01; 203(7):841-852. View abstract
  11. Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma. J Asthma. 2021 Mar 23; 1-9. View abstract
  12. Geography, generalisability, and susceptibility in clinical trials. Lancet Respir Med. 2021 04; 9(4):330-332. View abstract
  13. Validation of the Hospital Asthma Severity Score (HASS) in children ages 2-18 years old. J Asthma. 2020 Dec 02; 1-12. View abstract
  14. The Respiratory Risks of Ambient/Outdoor Air Pollution. Clin Chest Med. 2020 12; 41(4):809-824. View abstract
  15. Preventing asthma in high risk kids (PARK) with omalizumab: Design, rationale, methods, lessons learned and adaptation. Contemp Clin Trials. 2021 01; 100:106228. View abstract
  16. Asthma control and psychological health in pediatric severe asthma. Pediatr Pulmonol. 2021 01; 56(1):42-48. View abstract
  17. Asthma Prevalence and Mold Levels in US Northeastern Schools. J Allergy Clin Immunol Pract. 2021 03; 9(3):1312-1318. View abstract
  18. Differential Effect of School-Based Pollution Exposure in Children With Asthma Born Prematurely. Chest. 2020 10; 158(4):1361-1363. View abstract
  19. Supernumerary intrathoracic rib, a rare congenital anomaly: Case report and review of the literature. Pediatr Pulmonol. 2020 06; 55(6):1487-1489. View abstract
  20. Obesity may enhance the adverse effects of NO2 exposure in urban schools on asthma symptoms in children. J Allergy Clin Immunol. 2020 10; 146(4):813-820.e2. View abstract
  21. Proximity to major roadways and asthma symptoms in the School Inner-City Asthma Study. J Allergy Clin Immunol. 2020 01; 145(1):119-126.e4. View abstract
  22. Classroom indoor PM2.5 sources and exposures in inner-city schools. Environ Int. 2019 10; 131:104968. View abstract
  23. Screening and Counseling for Alcohol Use in Adolescents With Chronic Medical Conditions in the Ambulatory Setting. J Adolesc Health. 2019 06; 64(6):804-806. View abstract
  24. Pediatrician Attitudes toward Digital Voice Assistant Technology Use in Clinical Practice. Appl Clin Inform. 2019 03; 10(2):286-294. View abstract
  25. Association between fungal spore exposure in inner-city schools and asthma morbidity. Ann Allergy Asthma Immunol. 2019 06; 122(6):610-615.e1. View abstract
  26. Asthma and Corticosteroid Responses in Childhood and Adult Asthma. Clin Chest Med. 2019 03; 40(1):163-177. View abstract
  27. Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019 05; 143(5):1934-1937.e4. View abstract
  28. Question 3: Can we diagnose asthma in children under the age of 5?years? Paediatr Respir Rev. 2019 Feb; 29:25-30. View abstract
  29. Bronchodilator Use for Acute Chest Syndrome Among Large Pediatric Hospitals in North America. Clin Pediatr (Phila). 2018 12; 57(14):1630-1637. View abstract
  30. Transcutaneous CO-oximetry differentiates asthma exacerbation and convalescence in children. J Allergy Clin Immunol. 2018 08; 142(2):676-678.e5. View abstract
  31. Effects of endogenous sex hormones on lung function and symptom control in adolescents with asthma. BMC Pulm Med. 2018 Apr 10; 18(1):58. View abstract
  32. A Practical Approach to Severe Asthma in Children. Ann Am Thorac Soc. 2018 04; 15(4):399-408. View abstract
  33. The classroom microbiome and asthma morbidity in children attending 3 inner-city schools. J Allergy Clin Immunol. 2018 06; 141(6):2311-2313. View abstract
  34. Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations. N Engl J Med. 2018 Mar 08; 378(10):891-901. View abstract
  35. Advances in environmental and occupational disorders in 2016. J Allergy Clin Immunol. 2017 Dec; 140(6):1683-1692. View abstract
  36. Nitrogen dioxide exposure in school classrooms of inner-city children with asthma. J Allergy Clin Immunol. 2018 06; 141(6):2249-2255.e2. View abstract
  37. Baseline Features of the Severe Asthma Research Program (SARP III) Cohort: Differences with Age. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):545-554.e4. View abstract
  38. Adherence and stress in a population of inner-city children with asthma. Pediatr Allergy Immunol. 2017 09; 28(6):610-612. View abstract
  39. ATS Core Curriculum 2017: Part II. Pediatric Pulmonary Medicine. Ann Am Thorac Soc. 2017 08; 14(Suppl_2):S165-S181. View abstract
  40. The School Inner-City Asthma Intervention Study: Design, rationale, methods, and lessons learned. Contemp Clin Trials. 2017 09; 60:14-23. View abstract
  41. Effects of Age and Disease Severity on Systemic Corticosteroid Responses in Asthma. Am J Respir Crit Care Med. 2017 06 01; 195(11):1439-1448. View abstract
  42. Utilization of a patient-centered asthma passport tool in a subspecialty clinic. J Asthma. 2018 02; 55(2):180-187. View abstract
  43. Caregiver stress among inner-city school children with asthma. J Allergy Clin Immunol Pract. 2017 Jul - Aug; 5(4):1132-1134.e3. View abstract
  44. Inflammatory and Comorbid Features of Patients with Severe Asthma and Frequent Exacerbations. Am J Respir Crit Care Med. 2017 02 01; 195(3):302-313. View abstract
  45. Association Between Allergen Exposure in Inner-City Schools and Asthma Morbidity Among Students. JAMA Pediatr. 2017 01 01; 171(1):31-38. View abstract
  46. The Calculated Risk of Childhood Asthma From Severe Bronchiolitis. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):97-98. View abstract
  47. Comparison of treatment modalities for inpatient asthma exacerbations among US pediatric hospitals. J Allergy Clin Immunol Pract. 2017 May - Jun; 5(3):855-857.e1. View abstract
  48. Individualized therapy for persistent asthma in young children. J Allergy Clin Immunol. 2016 12; 138(6):1608-1618.e12. View abstract
  49. School Environmental Intervention to Reduce Particulate Pollutant Exposures for Children with Asthma. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):154-159.e3. View abstract
  50. Modeling indoor particulate exposures in inner-city school classrooms. J Expo Sci Environ Epidemiol. 2017 09; 27(5):451-457. View abstract
  51. Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma. N Engl J Med. 2016 Aug 18; 375(7):619-30. View abstract
  52. Utility of a portable hand-held forced expiratory volume in 1 second meter for monitoring asthma in an inner-city school setting. Ann Allergy Asthma Immunol. 2016 09; 117(3):323-4. View abstract
  53. Pediatric Rhinosinusitis. Curr Treat Options Allergy. 2016 Sep; 3(3):268-281. View abstract
  54. A Screening Tool for Assessing Alcohol Use Risk among Medically Vulnerable Youth. PLoS One. 2016; 11(5):e0156240. View abstract
  55. Association of FEF25%-75% and bronchodilator reversibility with asthma control and asthma morbidity in inner-city children with asthma. Ann Allergy Asthma Immunol. 2016 07; 117(1):97-9. View abstract
  56. Early Administration of Azithromycin and Prevention of Severe Lower Respiratory Tract Illnesses in Preschool Children With a History of Such Illnesses: A Randomized Clinical Trial. JAMA. 2015 Nov 17; 314(19):2034-2044. View abstract
  57. School Endotoxin Exposure and Asthma Morbidity in Inner-city Children. Chest. 2015 Nov; 148(5):1251-1258. View abstract
  58. Postnatal environmental tobacco smoke exposure is associated with objective markers of atopy in preschool-aged children. Evid Based Med. 2015 Dec; 20(6):219. View abstract
  59. Black and Hispanic perceptions of asthma medication in the School Inner-City Asthma Study. Ann Allergy Asthma Immunol. 2015 Jun; 114(6):533-4. View abstract
  60. Association between allergic sensitization and exhaled nitric oxide in children in the School Inner-City Asthma Study. Ann Allergy Asthma Immunol. 2015 Mar; 114(3):256-257.e1. View abstract
  61. Child with atopic dermatitis. Ann Allergy Asthma Immunol. 2015 Jan; 114(1):6-11. View abstract
  62. Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine. Environ Health Perspect. 2015 Jan; 123(1):6-20. View abstract
  63. Reprint of: Perinatal and early childhood environmental factors influencing allergic asthma immunopathogenesis. Int Immunopharmacol. 2014 Nov; 23(1):337-46. View abstract
  64. Perinatal and early childhood environmental factors influencing allergic asthma immunopathogenesis. Int Immunopharmacol. 2014 Sep; 22(1):21-30. View abstract
  65. The indoor environment and inner-city childhood asthma. Asian Pac J Allergy Immunol. 2014 Jun; 32(2):103-10. View abstract
  66. Social disadvantage and asthma control in children. Paediatr Respir Rev. 2014 Sep; 15(3):256-62; quiz 262-3. View abstract
  67. Allergens on desktop surfaces in preschools and elementary schools of urban children with asthma. Allergy. 2014 Jul; 69(7):960-963. View abstract
  68. Perceived neighborhood safety and asthma morbidity in the school inner-city asthma study. Pediatr Pulmonol. 2015 Jan; 50(1):17-24. View abstract
  69. ß-2 adrenergic receptor gene methylation is associated with decreased asthma severity in inner-city schoolchildren: asthma and rhinitis. Clin Exp Allergy. 2014; 44(5):681-9. View abstract
  70. Beta-2-Adrenergic Receptor Methylation Influences Asthma Phenotype in The School Inner City Asthma Study. Receptors Clin Investig. 2014; 1(1). View abstract
  71. Exposures to molds in school classrooms of children with asthma. Pediatr Allergy Immunol. 2013 Nov; 24(7):697-703. View abstract
  72. Rethinking the prevalence of exercise-induced bronchoconstriction in patients with asthma. Ann Allergy Asthma Immunol. 2013 Dec; 111(6):567-8. View abstract
  73. Food allergy and increased asthma morbidity in a School-based Inner-City Asthma Study. J Allergy Clin Immunol Pract. 2013 Sep-Oct; 1(5):479-84. View abstract
  74. Predictors of indoor exposure to mouse allergen in inner-city elementary schools. Ann Allergy Asthma Immunol. 2013 Oct; 111(4):299-301.e1. View abstract
  75. The utility of forced expiratory flow between 25% and 75% of vital capacity in predicting childhood asthma morbidity and severity. J Asthma. 2012 Aug; 49(6):586-92. View abstract
  76. Allergens in urban schools and homes of children with asthma. Pediatr Allergy Immunol. 2012 Sep; 23(6):543-9. View abstract
  77. Effect of cat and daycare exposures on the risk of asthma in children with atopic dermatitis. Allergy Asthma Proc. 2012 May-Jun; 33(3):282-8. View abstract
  78. Role of specific IgE and skin-prick testing in predicting food challenge results to baked egg. Allergy Asthma Proc. 2012 May-Jun; 33(3):275-81. View abstract
  79. Endotoxin exposure in inner-city schools and homes of children with asthma. Ann Allergy Asthma Immunol. 2012 Jun; 108(6):418-22. View abstract
  80. Parental response to written eczema action plans in children with eczema. Arch Dermatol. 2012 Mar; 148(3):391-2. View abstract
  81. The school inner-city asthma study: design, methods, and lessons learned. J Asthma. 2011 Dec; 48(10):1007-14. View abstract
  82. Agreement between parent and student responses to an asthma and allergy questionnaire in a diverse, inner-city elementary school population. Ann Allergy Asthma Immunol. 2011 Oct; 107(4):371-3. View abstract
  83. Research abstracts presented at the Fall Meeting of the New England Society of Allergy, October 23-24, 2010, Woodstock, Vermont. Allergy Asthma Proc. 2011 Jan 01; 32(1):80-81. View abstract
  84. Tree nut allergy, egg allergy, and asthma in children. Clin Pediatr (Phila). 2011 Feb; 50(2):133-9. View abstract
  85. The effect of prophylactic palivizumab on recurrent wheezing in children with an atopic family history. J Allergy Clin Immunol. 2011 Jan; 127(1):292-3; author reply 293. View abstract
  86. Clinically useful spirometry in preschool-aged children: evaluation of the 2007 American Thoracic Society Guidelines. J Asthma. 2010 Sep; 47(7):762-7. View abstract
  87. The role of indoor allergens in the development of asthma. Curr Opin Allergy Clin Immunol. 2009 Apr; 9(2):128-35. View abstract
  88. Peanut Allergy is Associated with Increased Asthma Prevalence in Food Allergic Children. AAAAI. 2009. View abstract
  89. Montelukast as Monotherapy for Pediatric Asthma. MP Med Prakt Pediatr. 2009; 3(63):20-23. View abstract
  90. Picture of the month. Blueberry muffin baby (extramedullary hematopoiesis) due to congenital cytomegalovirus infection. Arch Pediatr Adolesc Med. 2007 Nov; 161(11):1102-3. View abstract
  91. Sleep. Yale Curriculum in Primary Care. 2007. View abstract
  92. Sleep. Yale Curriculum in Primary Care. 2006. View abstract