Mark Gorman

Mark Gorman, MD

Assistant in Neurology; Director, Pediatric Multiple Sclerosis & Related Disorders Program; Director, Pediatric Neuro-Immunology Program

Assistant Professor of Neurology, Harvard Medical School

    Contact: 857-218-4794
  • Fax: 617-730-0285

Medical Services


  • Demyelinating Disorders
  • Multiple Sclerosis (MS)
  • Neuro-immunology
  • Opscolonus Myoclonus Syndrome
  • CNS vasculitis
  • Autoimmune Encephalitis


  • Neurology


  • English


  • Pediatric Neuro-Immunology Program
  • Pediatric Multiple Sclerosis and Related Disorders
To schedule an appointment: Call 857-218-4794 or Request an Appointment
Mark Gorman

I became very interested in working with children with disabilities during high school, when I volunteered at a summer camp for children with special needs.  

The first summer that I worked at a week-long overnight camp, between my sophomore and junior years of high school, I worked with a child with Down syndrome. I became fascinated by how the brain works and by what wasn't working properly. And after a week I was exhausted: On an emotional, personal and social level I developed a deep respect for the abilities of children with special needs and the families who help care for them. 

I started to read everything I could get my hands on about the brain. I went on to major in psychology with a focus in neuroscience at Duke University. During college I worked with Best Buddies, a group that matches students with young adults with intellectual disabilities, and greatly enjoyed these relationships.

From this personal interest, I trained in pediatric neurology. Through similarly moving patient-doctor relationships during my residency, I became fascinated by, and developed a specialization in, autoimmune diseases of the brain and spinal cord. I realized that often children and teens with these conditions were greatly in need of cohesive, coordinated care. 

Experience and Education


Undergraduate Degree

Duke University, 1997

Durham, North Carolina

Medical Degree

Harvard Medical School, 2001

Boston, Massachusetts


Pediatrics-Boston Children's Hospital, 2001 - 2003

Boston, Massachusetts


Pediatrics-Boston Children's Hospital, 2003 - 2006

Boston, Massachusetts


Multiple Sclerosis and Neuro-immunology-Partners Adult and Pediatric MS Centers, Brigham and Women's Hospital and Massachusetts General Hospital, 2006 - 2008

Boston, Massachusetts


Professional History

My practice specializes in pediatric neuroimmunology, which involves autoimmune conditions of the brain and spinal cord in children and adolescents. The most well-known condition within this field is multiple sclerosis (MS), but there are many other conditions, including opsoclonus myoclonus syndrome (OMS), autoimmune encephalitis, and central nervous system vasculitis, among others.

As a resident in both pediatrics and pediatric neurology at Boston Children's Hospital, I became fascinated clinically by demyelinating diseases (such as MS), a group of neuro-immune conditions in which the immune system damages the protective covering of the nerves called myelin. After finishing of my five-year residency, I completed a two-year fellowship in MS, becoming one of the first physicians nationwide with formal training in both pediatric neurology and multiple sclerosis.

Prior to my training, most children who presented with symptoms suggestive of demyelinating diseases would be referred out from Boston Children's Hospital to adult centers. I saw an unmet need to make great progress and help these children, and created Boston Children's first Pediatric Multiple Sclerosis Program.

With this base, I also started to see many children with other autoimmune disorders of brain and spinal cord. I was able to apply the knowledge and lessons I had learned in multiple sclerosis to these other conditions.

As an international expert in the care of children with these conditions, I have built my team from a small clinic into a large multidisciplinary program. My program includes nurses, nurse practitioners, psychologists, neuropsychologists, educational specialists and multiple consultants to address all of the medical, psychological, educational and social needs of the patients and families we see. In addition, I direct the hospital's inpatient neurology service and was in 2014 selected as the Department of Neurology's Teacher of the Year by the residents.


I am committed as a researcher to studying multiple neuro-immunologic diseases in children, with goals of diagnosing them promptly and treating them effectively.

My early work demonstrated increased relapse rates in pediatric versus adult onset patients with multiple sclerosis (MS). This paper has been widely referenced in subsequent publications and has informed our understanding of the highly active, inflammatory nature of the condition when it occurs in the pediatric age group. Data from my research was used to estimate the necessary sample sizes for clinical trials in pediatric MS.

The diseases I study are rare, and as such require considerable collaboration to build up a research base. At Boston Children's, we are a participating and high-enrolling site in the Network of Pediatric Multiple Sclerosis Centers, which conducts multi-institutional research to obtain data about pediatric multiple sclerosis and other demyelinating diseases of the central nervous system. The goals of the database are to describe the number and characteristics of patients with suspected pediatric early onset of demyelinating disease and provide a basis for hypothesis-driven research.

One of this group's major studies is investigating the cause of pediatric multiple sclerosis, looking at genetic and environmental contributions by comparing patients with pediatric onset multiple sclerosis to healthy controls. This study is now generating exciting data that has led to publications as well as numerous poster and oral presentations at the 2016 American Academy of Neurology meeting.

I am also part of a three-site research project on opsoclonus myoclonus syndrome (OMS). As the lead institution, we are examining clinical and neuropsychological outcomes of children with OMS.  Additional planned projects include assessment of relapse rates, development of a consensus statement, and creation of a larger multicenter clinical research database.

I also collaborate with researchers to discover novel infectious and autoimmune causes of encephalitis, a condition which often goes without a specific diagnosis, as well as autoimmune aspects of epilepsy. And several of my publications in both MS as well as other conditions have examined the efficacy and safety of immunological treatments in the neuro-immune conditions in the pediatric age group.  

As a leader in the study of these rare conditions, I believe my work is offering new hope for patients and families.

My studies include:

Gorman MP, Healy BC, Polgar-Turcsanyi, M, Chitnis, T. Increased relapse rate in pediatric-onset compared to adult-onset multiple sclerosis. Arch Neurol 2009 Jan;66(1):54-9. Full text:

Yeh EA, Waubant E, Krupp LB, Ness J, Chitnis T, Kuntz N, Ramanathan M, Belman A, ChabasD, Gorman MP, RodriguPez M, Rinker JR 2nd, Weinstock-Guttman B; for the National Network of Pediatric MS Centers of Excellence. Multiple sclerosis therapies in pediatric patients with refractory multiple sclerosis. Arch Neurol 2011 Apr;68(4):437-444.

Gorman MP, Tillema JM, Ciliax AM, Guttmann CR, Chitnis T. Daclizumab use in patients with pediatric multiple sclerosis. Arch Neurol 2012 Jan; 69(1):78-81.

Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttmann B, Yeh A, Rodriguez M, Ness J, Gorman M, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. BMC Neurol 2013 Nov 13;13(1):173. PMCID: PMC3832402.

Benson LA, Healy BC, Gorman MP, Baruch NF, Gholipour T, Musallam A, Chitnis T. Elevated relapse rates in pediatric compared to adult MS persist for at least 6 years. Multiple Sclerosis and Related Disorders. 2014;3(2):186-93.

Graves J, Grandhe S, Weinfurtner K, Krupp L, Nelman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E; US Network of Pediatric Multiple Sclerosis Centers. Protective environmental factors for neuromyelitis optica. Neurology. 2014 Nov 18;83(21):1923-9. PMCID: 4248458

Casper TC, Rose JW, Roalstad S, Waubant E, Aaen G, Belman A, Chitnis T, Gorman M, Krupp L, Lotze TE, Ness J, Patterson M, Rodriguez M, Weinstock-Guttman B, Browning B, Graves J, Tillema JM, Benson L, Harris Y, the U. S. Network of Pediatric Multiple Sclerosis Centers. The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps. J Child Neurol. 2014 Sep 30 [Epub ahead of print]. PMCID: 4379142.

To schedule an appointment: Call 857-218-4794 or Request an Appointment


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