Frank Twarog MD, PhD

Frank Twarog, MD, PhD

Professor, Harvard Medical School

  • Contact: 617-355-6117

  • Fax: 617-730-0310

Medical Services


  • Allergic Rhinitis
  • Allergy Immunology
  • Anaphylaxis
  • Asthma
  • Atopic Dermatitis
  • Drug Allergy
  • Eczema
  • Food Allergy
  • Immunotherapy


  • Allergy Immunology
  • Medicine


  • English
To schedule an appointment: Call 617-355-6117 or Request an Appointment

Experience and Education


Medical School

S.U.N.Y. Buffalo School of Medicine, 1971

Buffalo, NY

Immunology Medical School

State Univ NY, 1967

Buffalo, NY


Massachusetts General Hospital, 1971-1972

Boston, MA


Boston Children's Hospital, 1973-1974

Boston, MA


Boston Children's Hospital, 1974-1975

Boston, MA


  • Allergy/Immunology


Publications powered by Harvard Catalyst Profiles
  1. Hsu JT, Missmer SA, Young MC, Correia KF, Twarog FJ, Coughlin IB, Hornstein MD, Schneider LC. Prenatal food allergen exposures and odds of childhood peanut, tree nut, or sesame seed sensitization. Ann Allergy Asthma Immunol. 2013 Nov; 111(5):391-6.
  2. Rachid R, Leslie D, Schneider L, Twarog F. Reply. J Allergy Clin Immunol. 2011 Oct; 128(4):905.
  3. Gaffin JM, Sheehan WJ, Morrill J, Cinar M, Borras Coughlin IM, Sawicki GS, Twarog FJ, Young MC, Schneider LC, Phipatanakul W. Tree nut allergy, egg allergy, and asthma in children. Clin Pediatr (Phila). 2011 Feb; 50(2):133-9.
  4. Rachid R, Leslie D, Schneider L, Twarog F. Hypersensitivity to systemic corticosteroids: an infrequent but potentially life-threatening condition. J Allergy Clin Immunol. 2011 Feb; 127(2):524-8.
  5. Permaul P, Stutius LM, Sheehan WJ, Rangsithienchai P, Walter JE, Twarog FJ, Young MC, Scott JE, Schneider LC, Phipatanakul W. Sesame allergy: role of specific IgE and skin-prick testing in predicting food challenge results. Allergy Asthma Proc. 2009 Nov-Dec; 30(6):643-8.
  6. Lebovidge JS, Stone KD, Twarog FJ, Raiselis SW, Kalish LA, Bailey EP, Schneider LC. Development of a preliminary questionnaire to assess parental response to children's food allergies. Ann Allergy Asthma Immunol. 2006 Mar; 96(3):472-7.
  7. Turvey SE, Cronin B, Arnold AD, Twarog FJ, Dioun AF. Adverse reactions to vitamin B12 injections due to benzyl alcohol sensitivity: successful treatment with intranasal cyanocobalamin. Allergy. 2004 Sep; 59(9):1023-4.
  8. Alangari AA, Twarog FJ, Shih MC, Schneider LC. Clinical features and anaphylaxis in children with cold urticaria. Pediatrics. 2004 Apr; 113(4):e313-7.
  9. Orange JS, Song LA, Twarog FJ, Schneider LC. A patient with severe black fly (Simuliidae) hypersensitivity referred for evaluation of suspected immunodeficiency. Ann Allergy Asthma Immunol. 2004 Feb; 92(2):276-80.
  10. Teitelbaum JE, Fox VL, Twarog FJ, Nurko S, Antonioli D, Gleich G, Badizadegan K, Furuta GT. Eosinophilic esophagitis in children: immunopathological analysis and response to fluticasone propionate. Gastroenterology. 2002 May; 122(5):1216-25.
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  12. Salmun LM, Barlan I, Wolf HM, Eibl M, Twarog FJ, Geha RS, Schneider LC. Effect of intravenous immunoglobulin on steroid consumption in patients with severe asthma: a double-blind, placebo-controlled, randomized trial. J Allergy Clin Immunol. 1999 May; 103(5 Pt 1):810-5.
  13. Twarog FJ. Food-induced allergy in childhood. Allergy Asthma Proc. 1998 Jul-Aug; 19(4):219-22.
  14. Twarog FJ. Allergy and nursing. Allergy Asthma Proc. 1998 Jul-Aug; 19(4):209.
  15. Wolf SL, Twarog F, Weiler JM, Barron RJ, Lang DM, Wells JH, Zitt M, Virant FS, Katz RM, Banyash LW, et al. Discussion of risk of scuba diving in individuals with allergic and respiratory diseases: SCUBA Subcommittee. J Allergy Clin Immunol. 1995 Dec; 96(6 Pt 1):871-3.
  16. Towse A, O'Brien M, Twarog FJ, Braimon J, Moses AC. Local reaction secondary to insulin injection. A potential role for latex antigens in insulin vials and syringes. Diabetes Care. 1995 Aug; 18(8):1195-7.
  17. Twarog FJ. Home monitoring of asthma with peak expiratory flow rates. Ann Allergy. 1991 Nov; 67(5):457-60.
  18. Kamada MM, Twarog F, Leung DY. Multiple antibiotic sensitivity in a pediatric population. Allergy Proc. 1991 Sep-Oct; 12(5):347-50.
  19. Rappaport L, Coffman H, Guare R, Fenton T, DeGraw C, Twarog F. Effects of theophylline on behavior and learning in children with asthma. Am J Dis Child. 1989 Mar; 143(3):368-72.
  20. Katz AJ, Twarog FJ, Zeiger RS, Falchuk ZM. Milk-sensitive and eosinophilic gastroenteropathy: similar clinical features with contrasting mechanisms and clinical course. J Allergy Clin Immunol. 1984 Jul; 74(1):72-8.
  21. Fife D, Twarog FJ, Geha RS. Evaluation of clinical data in childhood asthma. Application of a computer file system. Am J Dis Child. 1983 Oct; 137(10):945-8.
  22. Twarog FJ. Urticaria in childhood: pathogenesis and management. Pediatr Clin North Am. 1983 Oct; 30(5):887-98.
  23. Harris A, Twarog FJ, Geha RS. Chronic urticaria in childhood: natural course and etiology. Ann Allergy. 1983 Aug; 51(2 Pt 1):161-5.
  24. Twarog FJ, Leung DY. Anaphylaxis to a component of isoetharine (sodium bisulfite). JAMA. 1982 Oct 22; 248(16):2030-1.
  25. Siegel RL, Twarog FJ. Emergency room therapy of the pediatric patient with status asthmaticus. J Asthma. 1982; 19(1):47-52.
  26. Geha RS, Rappaport JM, Twarog FJ, Parkman R, Rosen FS. Increased serum immunoglobulin E levels following allogeneic bone marrow transplantation. J Allergy Clin Immunol. 1980 Jul; 66(1):78-81.
  27. Schwartz AL, Lipton JM, Warburton D, Johnson LB, Twarog FJ. Management of acute asthma in childhood. A randomized evaluation of beta-adrenergic agents. Am J Dis Child. 1980 May; 134(5):474-8.
  28. Kohn BA, Twarog FJ, Geha RS. Differential effects of pharmacologic agents on EAC3 rosette formation by lymphocytes from normal and asthmatic subjects. J Allergy Clin Immunol. 1979 Sep; 64(3):182-8.
  29. Geha RS, Rappaport JM, Twarog FJ, Parkman R. Serum IgE levels following allogeneic bone marrow transplantation in man. Monogr Allergy. 1979; 14:81-5.
  30. Twarog FJ, Colten HR. Rational management of allergic disease: the role of immunotherapy. Pediatrics. 1977 Sep; 60(3):320-3.
  31. Soter NA, Joshi NP, Twarog FJ, Zeiger RS, Rothman PM, Colten HR. Delayed cold-induced urticaria: a dominantly inherited disorder. J Allergy Clin Immunol. 1977 Apr; 59(4):294-7.
  32. Twarog FJ, Picone FJ, Strunk RS, So J, Colten HR. Immediate hypersensitivity to cockroach. Isolation and purification of the major antigens. J Allergy Clin Immunol. 1977 Feb; 59(2):154-60.
  33. Twarog FJ, Weinstein SF, Khaw KT, Strieder DJ, Colten HR. Hypersensitivity to pancreatic extracts in parents of patients with cystic fibrosis. J Allergy Clin Immunol. 1977 Jan; 59(1):35-40.
  34. Zeiger RS, Twarog FJ, Colten HR. Histaminase release from human granulocytes. J Exp Med. 1976 Oct 1; 144(4):1049-61.
  35. Zeiger RS, Yurdin DL, Twarog FJ. Histamine metabolism. I. Thin-layer radiochromatographic assays for histaminase and histidine decarboxylase enzyme activities. J Lab Clin Med. 1976 Jun; 87(6):1065-74.
  36. Rose NR, Molotchnikoff MF, Twarog FJ. Factors affecting transfer of experimental autoimmune thyroiditis in rats. Immunology. 1973 May; 24(5):859-70.
  37. Twarog FJ, Rose NR. Antigenic competition between mouse thyroglobulin and bovine serum albumin demonstrated by adoptive transfer. J Immunol. 1971 Sep; 107(3):738-41.
  38. Rose NR, Twarog FJ, Crowle AJ. Murine thyroiditis: importance of adjuvant and mouse strain for the induction of thyroid lesions. J Immunol. 1971 Mar; 106(3):698-704.
  39. Twarog FJ, Rose NR. Transfer of autoimmune thyroiditis of the rat with lymph node cells. J Immunol. 1970 Jun; 104(6):1467-75.
  40. Twarog FJ, Kenney E, Rose NR. Adjuvants for the production of autoimmune thyroiditis in the rat. Proc Soc Exp Biol Med. 1970 Jan; 133(1):185-9.
  41. Rose NR, Twarog FJ. Antigen-induced refractory period of adoptive transfer. Transplant Proc. 1969 Mar; 1(1):564-6.
  42. Twarog FJ, Rose NR. The adjuvant effect of pertussis vaccine in experimental thyroiditis of the rat. Proc Soc Exp Biol Med. 1969 Feb; 130(2):434-9.
  43. Twarog FJ, Rose NR. A refractory period in adoptive immunization following secondary stimulation of mice. J Immunol. 1969 Feb; 102(2):375-80.
  44. Twarog FJ, Rose NR. The production of thyroid autoantibodies in mice. J Immunol. 1968 Aug; 101(2):242-50.
To schedule an appointment: Call 617-355-6117 or Request an Appointment


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