Current Environment: Production

David G. Nathan | Medical Services

Programs & Services

Languages

  • English

David G. Nathan | Education

Medical School

Harvard Medical School

Boston, MA

Internship

Brigham and Women's Hospital

Boston, MA

Residency

Brigham and Women's Hospital

Boston, MA

Fellowship

Brigham and Women's Hospital

Bethesda, MD

David G. Nathan | Certifications

  • American Board of Internal Medicine (General)

David G. Nathan | Publications

  1. Correcting the record on anemia of aging: a statistical reanalysis. Blood Adv. 2023 07 25; 7(14):3642-3643. View Correcting the record on anemia of aging: a statistical reanalysis. Abstract

  2. COVID-19, nuclear war, and global warming: lessons for our vulnerable world. Lancet. 2020 06 27; 395(10242):1967-1968. View COVID-19, nuclear war, and global warming: lessons for our vulnerable world. Abstract

  3. The Genetic Landscape of Diamond-Blackfan Anemia. Am J Hum Genet. 2018 12 06; 103(6):930-947. View The Genetic Landscape of Diamond-Blackfan Anemia. Abstract

  4. The Pathophysiology of Acquired Aplastic Anemia: Current Concepts Revisited. Hematol Oncol Clin North Am. 2018 Aug; 32(4):581-594. View The Pathophysiology of Acquired Aplastic Anemia: Current Concepts Revisited. Abstract

  5. Training. Pediatr Blood Cancer. 2018 02; 65(2). View Training. Abstract

  6. Cholesterol: the debate should be terminated. FASEB J. 2017 07; 31(7):2722-2728. View Cholesterol: the debate should be terminated. Abstract

  7. Eulogy for the clinical research center. J Clin Invest. 2016 07 01; 126(7):2388-91. View Eulogy for the clinical research center. Abstract

  8. Thalassemia: a look to the future. Ann N Y Acad Sci. 2016 03; 1368(1):11-5. View Thalassemia: a look to the future. Abstract

  9. Amino acid uptake in erythropoiesis. Sci Signal. 2015 Apr 14; 8(372):fs9. View Amino acid uptake in erythropoiesis. Abstract

  10. A conversation with David Nathan. J Clin Invest. 2014 Dec; 124(12):5090-1. View A conversation with David Nathan. Abstract

  11. Hereditary xerocytosis revisited. Am J Hematol. 2014 Dec; 89(12):1142-6. View Hereditary xerocytosis revisited. Abstract

  12. A tribute to Emil Frei III. J Clin Invest. 2013 Aug 1; 123(8):3188-9. View A tribute to Emil Frei III. Abstract

  13. Pathophysiology and Clinical Manifestations of the ß-Thalassemias. Cold Spring Harb Perspect Med. 2012 Dec 01; 2(12):a011726. View Pathophysiology and Clinical Manifestations of the ß-Thalassemias. Abstract

  14. Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. J Clin Invest. 2012 Jul; 122(7):2439-43. View Exome sequencing identifies GATA1 mutations resulting in Diamond-Blackfan anemia. Abstract

  15. Sickle cell disease (SCD), iNKT cells, and regadenoson infusion. Trans Am Clin Climatol Assoc. 2012; 123:312-7; discussion 317-8. View Sickle cell disease (SCD), iNKT cells, and regadenoson infusion. Abstract

  16. Fetal hemoglobin levels and morbidity in untransfused patients with ß-thalassemia intermedia. Blood. 2012 Jan 12; 119(2):364-7. View Fetal hemoglobin levels and morbidity in untransfused patients with ß-thalassemia intermedia. Abstract

  17. Guilt by association. Blood. 2011 Oct 06; 118(14):3758-9. View Guilt by association. Abstract

  18. Reversing the hemoglobin switch. N Engl J Med. 2010 Dec 02; 363(23):2258-60. View Reversing the hemoglobin switch. Abstract

  19. Thalassemia: an overview of 50 years of clinical research. Hematol Oncol Clin North Am. 2010 Dec; 24(6):1005-20. View Thalassemia: an overview of 50 years of clinical research. Abstract

  20. A life-long quest to understand and treat genetic blood disorders. Cell. 2010 Oct 01; 143(1):17-20. View A life-long quest to understand and treat genetic blood disorders. Abstract

  21. Pulmonary hypertension and nitric oxide depletion in sickle cell disease. Blood. 2010 Aug 05; 116(5):687-92. View Pulmonary hypertension and nitric oxide depletion in sickle cell disease. Abstract

  22. Musings on genome medicine: Hepatitis C. Genome Med. 2010 Jan 27; 2(1):4. View Musings on genome medicine: Hepatitis C. Abstract

  23. Sickle cell disease and stroke. Blood. 2009 Dec 10; 114(25):5117-25. View Sickle cell disease and stroke. Abstract

  24. Musings on genome medicine: enzyme-replacement therapy of the lysosomal storage diseases. Genome Med. 2009 Dec 09; 1(12):114. View Musings on genome medicine: enzyme-replacement therapy of the lysosomal storage diseases. Abstract

  25. Musings on genome medicine: Crohn's disease. Genome Med. 2009 Nov 05; 1(11):103. View Musings on genome medicine: Crohn's disease. Abstract

  26. Musings on genome medicine: the slow but inexorable process of medical care reform in the United States. Genome Med. 2009 Oct 12; 1(10):94. View Musings on genome medicine: the slow but inexorable process of medical care reform in the United States. Abstract

  27. Call for a slower approach to health care reform. J Clin Invest. 2009 Oct; 119(10):2847-8. View Call for a slower approach to health care reform. Abstract

  28. Musings on genome medicine: the Obama effect redux. Genome Med. 2009 Sep 11; 1(9):86. View Musings on genome medicine: the Obama effect redux. Abstract

  29. Musings on genome medicine: cholesterol and coronary artery disease. Genome Med. 2009 Jun 08; 1(6):60. View Musings on genome medicine: cholesterol and coronary artery disease. Abstract

  30. Musings on genome medicine: cancer genetics and the promise of effective treatment. Genome Med. 2009 May 06; 1(5):49. View Musings on genome medicine: cancer genetics and the promise of effective treatment. Abstract

  31. Musings on genome medicine: gene therapy. Genome Med. 2009 Apr 03; 1(4):38. View Musings on genome medicine: gene therapy. Abstract

  32. Musings on genome medicine: the Obama effect. Genome Med. 2009 Mar 09; 1(3):30. View Musings on genome medicine: the Obama effect. Abstract

  33. Musings on genome medicine: abuse of genetic tests. Genome Med. 2009 Feb 16; 1(2):18. View Musings on genome medicine: abuse of genetic tests. Abstract

  34. Musings on genome medicine: genome wide association studies. Genome Med. 2009 Jan 20; 1(1):3. View Musings on genome medicine: genome wide association studies. Abstract

  35. Judah Folkman, MD, 1933-2008. Pharos Alpha Omega Alpha Honor Med Soc. 2009; 4-8. View Judah Folkman, MD, 1933-2008. Abstract

  36. Targeting the cell death-survival equation. Clin Cancer Res. 2007 Dec 15; 13(24):7250-3. View Targeting the cell death-survival equation. Abstract

  37. Stanley J. Korsmeyer. Proc Am Philos Soc. 2007 Jun; 151(2):243-6. View Stanley J. Korsmeyer. Abstract

  38. Acceptance of the 2006 Kober medal. J Clin Invest. 2007 Apr; 117(4):1107-13. View Acceptance of the 2006 Kober medal. Abstract

  39. The cancer treatment revolution. Trans Am Clin Climatol Assoc. 2007; 118:317-23. View The cancer treatment revolution. Abstract

  40. Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2006 Dec; 79(6):1110-8. View Ribosomal protein S24 gene is mutated in Diamond-Blackfan anemia. Abstract

  41. NIH support for basic and clinical research: biomedical researcher angst in 2006. JAMA. 2006 Jun 14; 295(22):2656-8. View NIH support for basic and clinical research: biomedical researcher angst in 2006. Abstract

  42. The several Cs of translational clinical research. J Clin Invest. 2005 Apr; 115(4):795-7. View The several Cs of translational clinical research. Abstract

  43. New developments in iron chelators. Curr Opin Hematol. 2005 Mar; 12(2):129-34. View New developments in iron chelators. Abstract

  44. Thalassemia: the continued challenge. Ann N Y Acad Sci. 2005; 1054:1-10. View Thalassemia: the continued challenge. Abstract

  45. RNA and protein evidence for haplo-insufficiency in Diamond-Blackfan anaemia patients with RPS19 mutations. Br J Haematol. 2004 Oct; 127(1):105-13. View RNA and protein evidence for haplo-insufficiency in Diamond-Blackfan anaemia patients with RPS19 mutations. Abstract

  46. Determination can win the battle. Lancet. 2004 Jul 17-23; 364(9430):301. View Determination can win the battle. Abstract

  47. Acceptance of the 2003 John Howland Award: a journey in clinical research. Pediatr Res. 2004 Aug; 56(2):169-76. View Acceptance of the 2003 John Howland Award: a journey in clinical research. Abstract

  48. Clinical research and the NIH--a report card. N Engl J Med. 2003 Nov 06; 349(19):1860-5. View Clinical research and the NIH--a report card. Abstract

  49. First-trimester sex hormone binding globulin and subsequent gestational diabetes mellitus. Am J Obstet Gynecol. 2003 Jul; 189(1):171-6. View First-trimester sex hormone binding globulin and subsequent gestational diabetes mellitus. Abstract

  50. Deferiprone and hepatic fibrosis. Blood. 2003 Jun 15; 101(12):5089-90; author reply 5090-1. View Deferiprone and hepatic fibrosis. Abstract

  51. Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet. 2003 May 10; 361(9369):1597-602. View Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial. Abstract

  52. Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility. Lancet. 2003 Jan 11; 361(9352):183; author reply 183-4. View Deferiprone versus desferrioxamine in thalassaemia, and T2* validation and utility. Abstract

  53. Clinical research: a tale of two studies. Trans Am Clin Climatol Assoc. 2003; 114:219-30; discussion 230-2. View Clinical research: a tale of two studies. Abstract

  54. Academic freedom in clinical research. N Engl J Med. 2002 Oct 24; 347(17):1368-71. View Academic freedom in clinical research. Abstract

  55. A novel diagnostic screen for defects in the Fanconi anemia pathway. Blood. 2002 Dec 15; 100(13):4649-54. View A novel diagnostic screen for defects in the Fanconi anemia pathway. Abstract

  56. Careers in translational clinical research-historical perspectives, future challenges. JAMA. 2002 May 08; 287(18):2424-7. View Careers in translational clinical research-historical perspectives, future challenges. Abstract

  57. Educational-debt relief for clinical investigators--a vote of confidence. N Engl J Med. 2002 Jan 31; 346(5):372-4. View Educational-debt relief for clinical investigators--a vote of confidence. Abstract

  58. Comprehensive cancer centres and the war on cancer. Nat Rev Cancer. 2001 Dec; 1(3):240-5. View Comprehensive cancer centres and the war on cancer. Abstract

  59. Neurovisual abnormalities preceding the retinopathy in patients with long-term type 1 diabetes mellitus. Graefes Arch Clin Exp Ophthalmol. 2001 Sep; 239(9):643-8. View Neurovisual abnormalities preceding the retinopathy in patients with long-term type 1 diabetes mellitus. Abstract

  60. Evidence for linkage of familial Diamond-Blackfan anemia to chromosome 8p23.3-p22 and for non-19q non-8p disease. Blood. 2001 Apr 01; 97(7):2145-50. View Evidence for linkage of familial Diamond-Blackfan anemia to chromosome 8p23.3-p22 and for non-19q non-8p disease. Abstract

  61. The National Institutes of Health and clinical research: a progress report. Nat Med. 2000 Nov; 6(11):1201-4. View The National Institutes of Health and clinical research: a progress report. Abstract

  62. Congenital bone marrow failure syndromes. Br J Haematol. 2000 Oct; 111(1):30-42. View Congenital bone marrow failure syndromes. Abstract

  63. One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus. Blood. 1999 Apr 01; 93(7):2217-24. View One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus. Abstract

  64. Academia and industry: lessons from the unfortunate events in Toronto. Lancet. 1999 Mar 06; 353(9155):771-2. View Academia and industry: lessons from the unfortunate events in Toronto. Abstract

  65. Iron chelation with oral deferiprone in patients with thalassemia. N Engl J Med. 1998 Dec 03; 339(23):1711-2; author reply 1713-4. View Iron chelation with oral deferiprone in patients with thalassemia. Abstract

  66. Clinical research: perceptions, reality, and proposed solutions. National Institutes of Health Director's Panel on Clinical Research. JAMA. 1998 Oct 28; 280(16):1427-31. View Clinical research: perceptions, reality, and proposed solutions. National Institutes of Health Director's Panel on Clinical Research. Abstract

  67. Pioneers and modern ideas. Prospective on thalassemia. Pediatrics. 1998 Jul; 102(1 Pt 3):281-3; discussion 288-9. View Pioneers and modern ideas. Prospective on thalassemia. Abstract

  68. The beta chain of the interleukin-3 receptor functionally associates with the erythropoietin receptor. Blood. 1997 Sep 01; 90(5):1867-73. View The beta chain of the interleukin-3 receptor functionally associates with the erythropoietin receptor. Abstract

  69. The beta c component of the granulocyte-macrophage colony-stimulating factor (GM-CSF)/interleukin 3 (IL-3)/IL-5 receptor interacts with a hybrid GM-CSF/erythropoietin receptor to influence proliferation and beta-globin mRNA expression. Mol Med. 1996 Nov; 2(6):766-73. View The beta c component of the granulocyte-macrophage colony-stimulating factor (GM-CSF)/interleukin 3 (IL-3)/IL-5 receptor interacts with a hybrid GM-CSF/erythropoietin receptor to influence proliferation and beta-globin mRNA expression. Abstract

  70. Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3. J Biol Chem. 1996 Jun 14; 271(24):14020-7. View Cooperation between core binding factor and adjacent promoter elements contributes to the tissue-specific expression of interleukin-3. Abstract

  71. Diamond-Blackfan anemia. Natural history and sequelae of treatment. Medicine (Baltimore). 1996 Mar; 75(2):77-8. View Diamond-Blackfan anemia. Natural history and sequelae of treatment. Abstract

  72. Iron Deficiency Anemia Associated with an Error of Iron Metabolism in Two Siblings: A Thirty Year Follow Up. Hematology. 1996; 1(1):65-73. View Iron Deficiency Anemia Associated with an Error of Iron Metabolism in Two Siblings: A Thirty Year Follow Up. Abstract

  73. An orally active iron chelator. N Engl J Med. 1995 Apr 06; 332(14):953-4. View An orally active iron chelator. Abstract

  74. Survival in medically treated patients with homozygous beta-thalassemia. N Engl J Med. 1994 Sep 01; 331(9):574-8. View Survival in medically treated patients with homozygous beta-thalassemia. Abstract

  75. Interleukin-3 expression by activated T cells involves an inducible, T-cell-specific factor and an octamer binding protein. Blood. 1993 Feb 15; 81(4):928-34. View Interleukin-3 expression by activated T cells involves an inducible, T-cell-specific factor and an octamer binding protein. Abstract

  76. Academic careers: choice and activity of graduates of a pediatric residency program 1974-1986. Trans Am Clin Climatol Assoc. 1993; 104:180-95; discussion 195-7. View Academic careers: choice and activity of graduates of a pediatric residency program 1974-1986. Abstract

  77. Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate. Exp Hematol. 1992 Nov; 20(10):1156-64. View Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate. Abstract

  78. A service chief model for general pediatric inpatient care and residency training. Pediatrics. 1992 Apr; 89(4 Pt 1):601-7. View A service chief model for general pediatric inpatient care and residency training. Abstract

  79. Careers chosen by graduates of a major pediatrics residency program, 1974-1986. Acad Med. 1992 Apr; 67(4):272-4. View Careers chosen by graduates of a major pediatrics residency program, 1974-1986. Abstract

  80. Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell. Blood. 1990 Dec 15; 76(12):2443-8. View Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell. Abstract

  81. Intrinsic potential for high fetal hemoglobin production in a Druz family with beta-thalassemia is due to an unlinked genetic determinant. Hum Genet. 1990 Dec; 86(2):175-80. View Intrinsic potential for high fetal hemoglobin production in a Druz family with beta-thalassemia is due to an unlinked genetic determinant. Abstract

  82. The effect of desferrithiocin, an oral iron chelator, on T-cell function. Blood. 1990 Nov 15; 76(10):2052-9. View The effect of desferrithiocin, an oral iron chelator, on T-cell function. Abstract

  83. The treatment of Cooley's anemia. Haematologica. 1990 Sep-Oct; 75 Suppl 5:57-65. View The treatment of Cooley's anemia. Abstract

  84. Treatment of Cooley's anemia. Blood. 1990 Aug 01; 76(3):435-44. View Treatment of Cooley's anemia. Abstract

  85. Positive and negative elements regulate human interleukin 3 expression. Proc Natl Acad Sci U S A. 1990 Jul; 87(13):5046-50. View Positive and negative elements regulate human interleukin 3 expression. Abstract

  86. Regulation of hematopoiesis. Pediatr Res. 1990 May; 27(5):423-31. View Regulation of hematopoiesis. Abstract

  87. Oral iron chelators. Semin Hematol. 1990 Apr; 27(2):83-5. View Oral iron chelators. Abstract

  88. Pharmacologic manipulation of fetal hemoglobin in the hemoglobinopathies. Ann N Y Acad Sci. 1990; 612:179-83. View Pharmacologic manipulation of fetal hemoglobin in the hemoglobinopathies. Abstract

  89. The Jeremiah Metzger lecture. Regulation of hematopoiesis. Trans Am Clin Climatol Assoc. 1990; 101:135-53. View The Jeremiah Metzger lecture. Regulation of hematopoiesis. Abstract

  90. The beneficence of neonatal hematopoiesis. N Engl J Med. 1989 Oct 26; 321(17):1190-1. View The beneficence of neonatal hematopoiesis. Abstract

  91. Granulocyte-macrophage colony-stimulating factor and interleukin-3 mRNAs are produced by a small fraction of blood mononuclear cells. Blood. 1989 Oct; 74(5):1525-30. View Granulocyte-macrophage colony-stimulating factor and interleukin-3 mRNAs are produced by a small fraction of blood mononuclear cells. Abstract

  92. Beta-thalassemia due to two novel nucleotide substitutions in consensus acceptor splice sequences of the beta-globin gene. Blood. 1989 Mar; 73(4):914-8. View Beta-thalassemia due to two novel nucleotide substitutions in consensus acceptor splice sequences of the beta-globin gene. Abstract

  93. Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. Blood. 1989 Mar; 73(4):945-51. View Expression of human interleukin-3 (multi-CSF) is restricted to human lymphocytes and T-cell tumor lines. Abstract

  94. Combinations of recombinant colony-stimulating factors are required for optimal hematopoietic differentiation in serum-deprived culture. Blood. 1989 Feb 15; 73(3):688-93. View Combinations of recombinant colony-stimulating factors are required for optimal hematopoietic differentiation in serum-deprived culture. Abstract

  95. Saudi Arabian sickle cell anemia. A molecular approach. Ann N Y Acad Sci. 1989; 565:143-51. View Saudi Arabian sickle cell anemia. A molecular approach. Abstract

  96. Regulation of the human interleukin-3 gene. Trans Assoc Am Physicians. 1989; 102:240-51. View Regulation of the human interleukin-3 gene. Abstract

  97. Combinations of purified recombinant colony-stimulating factors are required for optimal hematopoietic differentiation. Trans Assoc Am Physicians. 1988; 101:282-7. View Combinations of purified recombinant colony-stimulating factors are required for optimal hematopoietic differentiation. Abstract

  98. Decreased hematopoietic accessory cell function following bone marrow transplantation. Exp Hematol. 1987 Nov; 15(10):1013-21. View Decreased hematopoietic accessory cell function following bone marrow transplantation. Abstract

  99. Leukemia and the regulation of hematopoiesis. Leukemia. 1987 Oct; 1(10):683-96. View Leukemia and the regulation of hematopoiesis. Abstract

  100. Stimulation of human hematopoietic colony formation by recombinant gibbon multi-colony-stimulating factor or interleukin 3. J Clin Invest. 1987 Sep; 80(3):818-23. View Stimulation of human hematopoietic colony formation by recombinant gibbon multi-colony-stimulating factor or interleukin 3. Abstract

  101. Analysis of hemoglobin F production in Saudi Arabian families with sickle cell anemia. Blood. 1987 Sep; 70(3):716-20. View Analysis of hemoglobin F production in Saudi Arabian families with sickle cell anemia. Abstract

  102. Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. J Clin Invest. 1987 Aug; 80(2):573-7. View Recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) shortens the period of neutropenia after autologous bone marrow transplantation in a primate model. Abstract

  103. Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle cell anemia. N Engl J Med. 1987 Jan 29; 316(5):244-50. View Molecular analysis of the high-hemoglobin-F phenotype in Saudi Arabian sickle cell anemia. Abstract

  104. Analysis of high fetal hemoglobin production in sickle cell anemia patients from the Eastern Province of Saudi Arabia. Prog Clin Biol Res. 1987; 251:415-26. View Analysis of high fetal hemoglobin production in sickle cell anemia patients from the Eastern Province of Saudi Arabia. Abstract

  105. Regulation of fetal hemoglobin synthesis in sickle cell anemia. Trans Am Clin Climatol Assoc. 1987; 98:21-8. View Regulation of fetal hemoglobin synthesis in sickle cell anemia. Abstract

  106. Investigations of the simian ontogenic switch from fetal to adult hemoglobin at the progenitor cell level. J Clin Invest. 1986 Dec; 78(6):1497-503. View Investigations of the simian ontogenic switch from fetal to adult hemoglobin at the progenitor cell level. Abstract

  107. High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined. Blood. 1986 May; 67(5):1404-10. View High fetal hemoglobin production in sickle cell anemia in the eastern province of Saudi Arabia is genetically determined. Abstract

  108. Dependence of highly enriched human bone marrow progenitors on hemopoietic growth factors and their response to recombinant erythropoietin. J Clin Invest. 1986 Jan; 77(1):74-81. View Dependence of highly enriched human bone marrow progenitors on hemopoietic growth factors and their response to recombinant erythropoietin. Abstract

  109. Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment. Blood. 1985 Dec; 66(6):1247-50. View Bone marrow transplantation for paroxysmal nocturnal hemoglobinuria: eradication of the PNH clone and documentation of complete lymphohematopoietic engraftment. Abstract

  110. Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity. J Clin Invest. 1985 Sep; 76(3):1286-90. View Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity. Abstract

  111. Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesis. J Clin Invest. 1985 Jun; 75(6):1999-2005. View Influence of cell cycle phase-specific agents on simian fetal hemoglobin synthesis. Abstract

  112. Determination of the hemoglobin F program in human progenitor-derived erythroid cells. J Clin Invest. 1985 Apr; 75(4):1359-68. View Determination of the hemoglobin F program in human progenitor-derived erythroid cells. Abstract

  113. Identification of three accessory cell populations in human bone marrow with erythroid burst-promoting properties. J Clin Invest. 1985 Apr; 75(4):1278-84. View Identification of three accessory cell populations in human bone marrow with erythroid burst-promoting properties. Abstract

  114. Current therapy and new approaches to the treatment of thalassemia major. Ann N Y Acad Sci. 1985; 445:248-55. View Current therapy and new approaches to the treatment of thalassemia major. Abstract

  115. Regulation of fetal hemoglobin synthesis by cell cycle specific drugs. Prog Clin Biol Res. 1985; 191:475-500. View Regulation of fetal hemoglobin synthesis by cell cycle specific drugs. Abstract

  116. Regulation of fetal hemoglobin synthesis in the hemoglobinopathies. Ann N Y Acad Sci. 1985; 445:177-87. View Regulation of fetal hemoglobin synthesis in the hemoglobinopathies. Abstract

  117. Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia. J Clin Invest. 1984 Aug; 74(2):652-6. View Hydroxyurea enhances fetal hemoglobin production in sickle cell anemia. Abstract

  118. Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea. N Engl J Med. 1984 Apr 05; 310(14):869-73. View Augmentation of fetal-hemoglobin production in anemic monkeys by hydroxyurea. Abstract

  119. Hydroxyurea increases fetal hemoglobin production in sickle cell anemia. Trans Assoc Am Physicians. 1984; 97:268-74. View Hydroxyurea increases fetal hemoglobin production in sickle cell anemia. Abstract

  120. Nutrition classics: the Journal of Clinical Investigation, volume 43, 1964. Iron deficiency anemia associated with an error of iron metabolism in two siblings. Nutr Rev. 1983 Oct; 41(10):315-7. View Nutrition classics: the Journal of Clinical Investigation, volume 43, 1964. Iron deficiency anemia associated with an error of iron metabolism in two siblings. Abstract

  121. Evidence for genetic restriction in the suppression of erythropoiesis by a unique subset of T lymphocytes in man. J Clin Invest. 1983 Aug; 72(2):694-706. View Evidence for genetic restriction in the suppression of erythropoiesis by a unique subset of T lymphocytes in man. Abstract

  122. Synthesis of hemoglobin F in adult simian erythroid progenitor-derived colonies. J Clin Invest. 1982 Oct; 70(4):752-61. View Synthesis of hemoglobin F in adult simian erythroid progenitor-derived colonies. Abstract

  123. Clinical removal of iron. Annu Rev Med. 1982; 33:509-19. View Clinical removal of iron. Abstract

  124. Exercise-induced hemolysis in xerocytosis. Erythrocyte dehydration and shear sensitivity. J Clin Invest. 1981 Sep; 68(3):631-8. View Exercise-induced hemolysis in xerocytosis. Erythrocyte dehydration and shear sensitivity. Abstract

  125. Heterogeneity of DNA deletion in gamma delta beta-thalassemia. J Clin Invest. 1981 Mar; 67(3):878-84. View Heterogeneity of DNA deletion in gamma delta beta-thalassemia. Abstract

  126. Control of the simian fetal hemoglobin switch at the progenitor cell level. J Clin Invest. 1981 Feb; 67(2):458-66. View Control of the simian fetal hemoglobin switch at the progenitor cell level. Abstract

  127. The molecular genetics of thalassemia. Adv Hum Genet. 1981; 11:233-80. View The molecular genetics of thalassemia. Abstract

  128. Treatment of acute myelogenous leukemia in children and adults. N Engl J Med. 1980 Aug 28; 303(9):473-8. View Treatment of acute myelogenous leukemia in children and adults. Abstract

  129. Aplastic and hypoplastic anemia. Pediatr Clin North Am. 1980 May; 27(2):217-35. View Aplastic and hypoplastic anemia. Abstract

  130. New approaches to the transfusion management of thalassemia. Blood. 1980 Jan; 55(1):55-60. View New approaches to the transfusion management of thalassemia. Abstract

  131. F-cell regulation. Ann N Y Acad Sci. 1980; 344:219-32. View F-cell regulation. Abstract

  132. Monocytes do not inhibit peripheral blood erythroid burst forming unit colony formation. J Clin Invest. 1980 Jan; 65(1):219-23. View Monocytes do not inhibit peripheral blood erythroid burst forming unit colony formation. Abstract

  133. Prenatal diagnosis of hemoglobinopathies: the New England approach. Ann N Y Acad Sci. 1980; 344:151-64. View Prenatal diagnosis of hemoglobinopathies: the New England approach. Abstract

  134. Prenatal diagnosis of hemoglobinopathies. Clin Perinatol. 1979 Sep; 6(2):275-91. View Prenatal diagnosis of hemoglobinopathies. Abstract

  135. Progress in thalassemia research. Nature. 1979 Jul 26; 280(5720):275-6. View Progress in thalassemia research. Abstract

  136. The molecular basis of alpha-thalassemias: frequent occurrence of dysfunctional alpha loci among non-Asians with Hb H disease. Cell. 1979 May; 17(1):33-42. View The molecular basis of alpha-thalassemias: frequent occurrence of dysfunctional alpha loci among non-Asians with Hb H disease. Abstract

  137. Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia. Proc Natl Acad Sci U S A. 1979 May; 76(5):2400-4. View Partial deletion of beta-globin gene DNA in certain patients with beta 0-thalassemia. Abstract

  138. Application of endonuclease mapping to the analysis and prenatal diagnosis of thalassemias caused by globin-gene deletion. N Engl J Med. 1978 Jul 27; 299(4):166-72. View Application of endonuclease mapping to the analysis and prenatal diagnosis of thalassemias caused by globin-gene deletion. Abstract

  139. Antenatal diagnosis of thalassaemia major. Br Med J. 1978 Feb 11; 1(6109):350-3. View Antenatal diagnosis of thalassaemia major. Abstract

  140. Erythroid precursors in congenital hypoplastic (Diamond-Blackfan) anemia. J Clin Invest. 1978 Feb; 61(2):489-98. View Erythroid precursors in congenital hypoplastic (Diamond-Blackfan) anemia. Abstract

  141. Treatment of iron overload in adults with continuous parenteral desferrioxamine. Am J Med. 1977 Dec; 63(6):958-66. View Treatment of iron overload in adults with continuous parenteral desferrioxamine. Abstract

  142. Continuous subcutaneous administration of deferoxamine in patients with iron overload. N Engl J Med. 1977 08 25; 297(8):418-23. View Continuous subcutaneous administration of deferoxamine in patients with iron overload. Abstract

  143. Evaluation of continuous desferrioxamine administration in adults with transfusional hemosiderosis. Trans Assoc Am Physicians. 1977; 90:335-41. View Evaluation of continuous desferrioxamine administration in adults with transfusional hemosiderosis. Abstract

  144. Prenatal diagnosis of hemoglobinopathies: detection of alpha-thalassemia trait and of sickle cell disease in utero. Hemoglobin. 1977; 1(4):395-400. View Prenatal diagnosis of hemoglobinopathies: detection of alpha-thalassemia trait and of sickle cell disease in utero. Abstract

  145. Fetal research: an investigator's view. Villanova Law Rev. 1977 Jan; 22(2):384-94. View Fetal research: an investigator's view. Abstract

  146. Prenatal diagnosis of hemoglobinopathies. A review of 15 cases. N Engl J Med. 1976 Dec 23; 295(26):1437-43. View Prenatal diagnosis of hemoglobinopathies. A review of 15 cases. Abstract

  147. The thalassemias. N Engl J Med. 1976 Sep 23; 295(13):710-4. View The thalassemias. Abstract

  148. Reassessment of the use of desferrioxamine B in iron overload. N Engl J Med. 1976 Jun 24; 294(26):1421-3. View Reassessment of the use of desferrioxamine B in iron overload. Abstract

  149. Prenatal diagnosis of sickle-cell anemia and alpha G Philadelphia. Study of a Fetus also at risk for H b S/beta+-thalassemia. N Engl J Med. 1976 May 06; 294(19):1040-1. View Prenatal diagnosis of sickle-cell anemia and alpha G Philadelphia. Study of a Fetus also at risk for H b S/beta+-thalassemia. Abstract

  150. The acute and transient nature of idiopathic immune hemolytic anemia in childhood. J Pediatr. 1976 May; 88(5):780-3. View The acute and transient nature of idiopathic immune hemolytic anemia in childhood. Abstract

  151. Molecular pathology of the thalassemias. Adv Intern Med. 1976; 21:97-128. View Molecular pathology of the thalassemias. Abstract

  152. The molecular genetics of thalassemia. Birth Defects Orig Artic Ser. 1976; 12(8):145-59. View The molecular genetics of thalassemia. Abstract

  153. Expression of the beta-thalassemia gene in the first trimester fetus. Proc Natl Acad Sci U S A. 1975 Sep; 72(9):3633-7. View Expression of the beta-thalassemia gene in the first trimester fetus. Abstract

  154. Antenatal diagnosis of hemoglobinopathies: social and technical considerations. Semin Hematol. 1975 Jul; 12(3):305-21. View Antenatal diagnosis of hemoglobinopathies: social and technical considerations. Abstract

  155. Hemoglobin Syracuse (alpha2beta2-143(H21)His leads to Pro), a new high-affinity variant detected by special electrophoretic methods. Observations on the auto-oxidation of normal and variant hemoglobins. J Clin Invest. 1975 Mar; 55(3):469-77. View Hemoglobin Syracuse (alpha2beta2-143(H21)His leads to Pro), a new high-affinity variant detected by special electrophoretic methods. Observations on the auto-oxidation of normal and variant hemoglobins. Abstract

  156. Thalassemia. Annu Rev Med. 1975; 26:345-51. View Thalassemia. Abstract

  157. Progress in the methodology for antenatal diagnosis of the beta chain hemoglobinopathies. Trans Assoc Am Physicians. 1975; 88:168-76. View Progress in the methodology for antenatal diagnosis of the beta chain hemoglobinopathies. Abstract

  158. Ethical problems in fetal research. J Gen Educ. 1975; 27(3):165-75. View Ethical problems in fetal research. Abstract

  159. Globin translation in thalassemic bone marrow. Ann N Y Acad Sci. 1974 Nov 29; 241(0):253-61. View Globin translation in thalassemic bone marrow. Abstract

  160. In utero diagnosis of hemoglobinopathies. Hemoglobin synthesis in fetal red cells. N Engl J Med. 1974 05 09; 290(19):1067-8. View In utero diagnosis of hemoglobinopathies. Hemoglobin synthesis in fetal red cells. Abstract

  161. Relation of beta to gamma synthesis during the first trimester: an approach to prenatal diagnosis of thalassemia. Pediatr Res. 1974 May; 8(5):553-60. View Relation of beta to gamma synthesis during the first trimester: an approach to prenatal diagnosis of thalassemia. Abstract

  162. Intrauterine diagnosis of thalassemia. Ann N Y Acad Sci. 1974; 232(0):145-51. View Intrauterine diagnosis of thalassemia. Abstract

  163. Translational control of hemoglobin synthesis in thalassemic bone marrow. Ann N Y Acad Sci. 1974; 232(0):40-3. View Translational control of hemoglobin synthesis in thalassemic bone marrow. Abstract

  164. Effects of cyanate and 2,3-diphosphoglycerate on sickling. Relationship to oxygenation. J Clin Invest. 1973 Oct; 52(10):2542-7. View Effects of cyanate and 2,3-diphosphoglycerate on sickling. Relationship to oxygenation. Abstract

  165. The mortality of acquired aplastic anemia in children. Blood. 1972 Aug; 40(2):153-62. View The mortality of acquired aplastic anemia in children. Abstract

  166. Equal synthesis of - and -globin chains in erythroid precursors in heterozygous -thalassemia. J Clin Invest. 1972 Jul; 51(7):1906-9. View Equal synthesis of - and -globin chains in erythroid precursors in heterozygous -thalassemia. Abstract

  167. Energy metabolism in human erythrocytes. II. Effects of glucose depletion. J Clin Invest. 1972 Jun; 51(6):1547-54. View Energy metabolism in human erythrocytes. II. Effects of glucose depletion. Abstract

  168. Thalassemia. N Engl J Med. 1972 Mar 16; 286(11):586-94. View Thalassemia. Abstract

  169. Changes in fatty acid metabolism after erythrocyte peroxidation: stimulation of a membrane repair process. J Clin Invest. 1972 Feb; 51(2):338-44. View Changes in fatty acid metabolism after erythrocyte peroxidation: stimulation of a membrane repair process. Abstract

  170. Gamma-beta thalassemia: a cause of hemolytic disease of the newborn. N Engl J Med. 1972 Jan 20; 286(3):129-34. View Gamma-beta thalassemia: a cause of hemolytic disease of the newborn. Abstract

  171. Oxidant injury of caucasian glucose-6-phosphate dehydrogenase-deficient red blood cells by phagocytosing leukocytes during infection. J Clin Invest. 1971 Dec; 50(12):2466-73. View Oxidant injury of caucasian glucose-6-phosphate dehydrogenase-deficient red blood cells by phagocytosing leukocytes during infection. Abstract

  172. Amino acid oxidase of leukocytes in relation to H 2 O 2 -mediated bacterial killing. J Clin Invest. 1971 Sep; 50(9):1985-91. View Amino acid oxidase of leukocytes in relation to H 2 O 2 -mediated bacterial killing. Abstract

  173. Energy metabolism in human erythrocytes. I. Effects of sodium fluoride. J Clin Invest. 1971 Aug; 50(8):1731-7. View Energy metabolism in human erythrocytes. I. Effects of sodium fluoride. Abstract

  174. Selective reticulocyte destruction in erythrocyte pyruvate kinase deficiency. J Clin Invest. 1971 Mar; 50(3):688-99. View Selective reticulocyte destruction in erythrocyte pyruvate kinase deficiency. Abstract

  175. Endogenous production of carbon monoxide in normal and erythroblastotic newborn infants. J Clin Invest. 1971 Jan; 50(1):1-8. View Endogenous production of carbon monoxide in normal and erythroblastotic newborn infants. Abstract

  176. Normal and variant isoenzymes of human blood cell hexokinase and the isoenzyme patterns in hemolytic anemia. Blood. 1970 Aug; 36(2):219-27. View Normal and variant isoenzymes of human blood cell hexokinase and the isoenzyme patterns in hemolytic anemia. Abstract

  177. Correction of metabolic deficiencies in the leukocytes of patients with chronic granulomatous disease. J Clin Invest. 1970 May; 49(5):865-70. View Correction of metabolic deficiencies in the leukocytes of patients with chronic granulomatous disease. Abstract

  178. Mild thalassemia: the result of interactions of alpha and beta thalassemia genes. J Clin Invest. 1970 Apr; 49(4):635-42. View Mild thalassemia: the result of interactions of alpha and beta thalassemia genes. Abstract

  179. Mild thalassemia--a guide to therapy. N Engl J Med. 1969 Dec 11; 281(24):1363-4. View Mild thalassemia--a guide to therapy. Abstract

  180. Unbalanced globin chain synthesis in alpha-thalassemia heterozygotes. Ann N Y Acad Sci. 1969 Nov 20; 165(1):288-94. View Unbalanced globin chain synthesis in alpha-thalassemia heterozygotes. Abstract

  181. Globin chain synthesis in the alpha thalassemia syndromes. J Clin Invest. 1969 Nov; 47(11):2512-22. View Globin chain synthesis in the alpha thalassemia syndromes. Abstract

  182. Failure of nitro blue tetrazolium reduction in the phagocytic vacuoles of leukocytes in chronic granulomatous disease. J Clin Invest. 1969 Oct; 48(10):1895-904. View Failure of nitro blue tetrazolium reduction in the phagocytic vacuoles of leukocytes in chronic granulomatous disease. Abstract

  183. Influence of hemoglobin precipitation on erythrocyte metabolism in alpha and beta thalassemia. J Clin Invest. 1969 Jan; 48(1):33-41. View Influence of hemoglobin precipitation on erythrocyte metabolism in alpha and beta thalassemia. Abstract

  184. Stages in the incorporation of fatty acids into red blood cells. J Clin Invest. 1968 May; 47(5):1096-108. View Stages in the incorporation of fatty acids into red blood cells. Abstract

  185. Erythrocyte production and metabolism in anephric and uremic men. Ann N Y Acad Sci. 1968 Mar 29; 149(1):539-43. View Erythrocyte production and metabolism in anephric and uremic men. Abstract

  186. Hemoglobin F and beta thalassemia. Science. 1967 Sep 01; 157(3792):1079. View Hemoglobin F and beta thalassemia. Abstract

  187. THE METABOLISM OF THE INDIVIDUAL C14 LABELED HEMOGLOBINS IN PATIENTS WITH H-THALASSEMIA, WITH OBSERVATIONS ON RADIOCHROMATE BINDING TO THE HEMOGLOBINS DURING RED CELL SURVIVAL. J Clin Invest. 1965 Feb; 44:315-25. View THE METABOLISM OF THE INDIVIDUAL C14 LABELED HEMOGLOBINS IN PATIENTS WITH H-THALASSEMIA, WITH OBSERVATIONS ON RADIOCHROMATE BINDING TO THE HEMOGLOBINS DURING RED CELL SURVIVAL. Abstract

  188. ERYTHROPOIESIS IN ANEPHRIC MAN. J Clin Invest. 1964 Nov; 43:2158-65. View ERYTHROPOIESIS IN ANEPHRIC MAN. Abstract

  189. THALASSEMIA TRAIT. GENETIC COMBINATIONS OF INCREASED FETAL AND A2 HEMOGLOBINS. N Engl J Med. 1964 Jun 04; 270:1212-7. View THALASSEMIA TRAIT. GENETIC COMBINATIONS OF INCREASED FETAL AND A2 HEMOGLOBINS. Abstract

  190. IRON DEFICIENCY ANEMIA ASSOCIATED WITH AN ERROR OF IRON METABOLISM IN TWO SIBLINGS. J Clin Invest. 1964 Mar; 43:510-21. View IRON DEFICIENCY ANEMIA ASSOCIATED WITH AN ERROR OF IRON METABOLISM IN TWO SIBLINGS. Abstract

  191. THE TURNOVER OF HEMOGLOBINS A, F, AND A(2) IN THE PERIPHERAL BLOOD OF THREE PATIENTS WITH THALASSEMIA. J Clin Invest. 1963 Nov; 42(11):1678-88. View THE TURNOVER OF HEMOGLOBINS A, F, AND A(2) IN THE PERIPHERAL BLOOD OF THREE PATIENTS WITH THALASSEMIA. Abstract

  192. THE EFFECT OF ANDROGENS ON SOME ASPECTS OF BODY COMPOSITION AND ERYTHROPOISIS IN OCTOGENARIAN MALES. Ann N Y Acad Sci. 1963 Sep 26; 110:965-77. View THE EFFECT OF ANDROGENS ON SOME ASPECTS OF BODY COMPOSITION AND ERYTHROPOISIS IN OCTOGENARIAN MALES. Abstract

  193. Erythroid cell maturation and hemoglobin synthesis in megaloblastic anemia. J Clin Invest. 1962 May; 41:1086-93. View Erythroid cell maturation and hemoglobin synthesis in megaloblastic anemia. Abstract

  194. The synthesis of heme and globin in the maturing human erythroid cell. J Clin Invest. 1961 Jun; 40:940-6. View The synthesis of heme and globin in the maturing human erythroid cell. Abstract

  195. Hypochromic anemia and hemochromatosis--response to combined testosterone, pyridoxine, and liver extract therapy. Trans Am Clin Climatol Assoc. 1961; 73:121-35. View Hypochromic anemia and hemochromatosis--response to combined testosterone, pyridoxine, and liver extract therapy. Abstract

  196. The passage of ammonia across the blood-brain-barrier and its relation to blood pH. J Clin Invest. 1958 Dec; 37(12):1724-8. View The passage of ammonia across the blood-brain-barrier and its relation to blood pH. Abstract

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