Medical School

  • Harvard Medical School , 1974 , Boston , MA


  • Boston Children's Hospital , 1976 , Boston , MA


  • Dana-Farber/Boston Children's Cancer and Blood Disorders Center , 1979 , Boston , MA


Dr. Peter E. Newburger is a physician-scientist focused on caring for patients with non-malignant hematologic disorders with a special interest in diseases of white blood cell number and function. Dr. Newburger’s laboratory uses human and mouse genetics to understand white blood cell production and function, how this goes awry in disease, and how to correct genetic disorders by gene therapy.


  • American Board of Pediatrics, General Pediatrics
  • American Board of Pediatrics, Pediatric Hematology and Oncology


Publications powered by Harvard Catalyst Profiles

  1. Bianchi P, Fermo E, Lezon-Geyda K, van Beers EJ, Morton HD, Barcellini W, Glader B, Chonat S, Ravindranath Y, Newburger PE, Kollmar N, Despotovic JM, Verhovsek M, Sharma M, Kwiatkowski JL, Kuo KHM, Wlodarski MW, Yaish HM, Holzhauer S, Wang H, Kunz J, Addonizio K, Al-Sayegh H, London WB, Andres O, van Wijk R, Gallagher PG, Grace RFF. Genotype-phenotype correlation and molecular heterogeneity in pyruvate kinase deficiency. Am J Hematol. 2020 05; 95(5):472-482. View abstract
  2. Kohn DB, Booth C, Kang EM, Pai SY, Shaw KL, Santilli G, Armant M, Buckland KF, Choi U, De Ravin SS, Dorsey MJ, Kuo CY, Leon-Rico D, Rivat C, Izotova N, Gilmour K, Snell K, Dip JX, Darwish J, Morris EC, Terrazas D, Wang LD, Bauser CA, Paprotka T, Kuhns DB, Gregg J, Raymond HE, Everett JK, Honnet G, Biasco L, Newburger PE, Bushman FD, Grez M, Gaspar HB, Williams DA, Malech HL, Galy A, Thrasher AJ. Lentiviral gene therapy for X-linked chronic granulomatous disease. Nat Med. 2020 02; 26(2):200-206. View abstract
  3. Rao S, Brito-Frazao J, Serbin AV, Yao Q, Luk K, Wu Y, Zeng J, Ren C, Watkinson R, Armant M, Pinello L, Shimamura A, Lee B, Wolfe SA, Newburger PE, Bauer DE. Gene Editing ELANE in Human Hematopoietic Stem and Progenitor Cells Reveals Disease Mechanisms and Therapeutic Strategies for Severe Congenital Neutropenia. Blood. 2019 Nov 13; 134(Supplement_1):3. View abstract
  4. Atallah-Yunes SA, Ready A, Newburger PE. Benign ethnic neutropenia. Blood Rev. 2019 09; 37:100586. View abstract
  5. Gallagher PG, Maksimova Y, Lezon-Geyda K, Newburger PE, Medeiros D, Hanson RD, Rothman J, Israels S, Wall DA, Sidonio RF, Sieff C, Gowans LK, Mittal N, Rivera-Santiago R, Speicher DW, Baserga SJ, Schulz VP. Aberrant splicing contributes to severe a-spectrin-linked congenital hemolytic anemia. J Clin Invest. 2019 04 30; 129(7):2878-2887. View abstract
  6. Ulirsch JC, Verboon JM, Kazerounian S, Guo MH, Yuan D, Ludwig LS, Handsaker RE, Abdulhay NJ, Fiorini C, Genovese G, Lim ET, Cheng A, Cummings BB, Chao KR, Beggs AH, Genetti CA, Sieff CA, Newburger PE, Niewiadomska E, Matysiak M, Vlachos A, Lipton JM, Atsidaftos E, Glader B, Narla A, Gleizes PE, O'Donohue MF, Montel-Lehry N, Amor DJ, McCarroll SA, O'Donnell-Luria AH, Gupta N, Gabriel SB, MacArthur DG, Lander ES, Lek M, Da Costa L, Nathan DG, Korostelev AA, Do R, Sankaran VG, Gazda HT. The Genetic Landscape of Diamond-Blackfan Anemia. Am J Hum Genet. 2019 Feb 07; 104(2):356. View abstract
  7. Furutani E, Newburger PE, Shimamura A. Neutropenia in the age of genetic testing: Advances and challenges. Am J Hematol. 2019 03; 94(3):384-393. View abstract
  8. Chiang JC, Jiang J, Newburger PE, Lawrence JB. Trisomy silencing by XIST normalizes Down syndrome cell pathogenesis demonstrated for hematopoietic defects in vitro. Nat Commun. 2018 12 05; 9(1):5180. View abstract
  9. Ulirsch JC, Verboon JM, Kazerounian S, Guo MH, Yuan D, Ludwig LS, Handsaker RE, Abdulhay NJ, Fiorini C, Genovese G, Lim ET, Cheng A, Cummings BB, Chao KR, Beggs AH, Genetti CA, Sieff CA, Newburger PE, Niewiadomska E, Matysiak M, Vlachos A, Lipton JM, Atsidaftos E, Glader B, Narla A, Gleizes PE, O'Donohue MF, Montel-Lehry N, Amor DJ, McCarroll SA, O'Donnell-Luria AH, Gupta N, Gabriel SB, MacArthur DG, Lander ES, Lek M, Da Costa L, Nathan DG, Korostelev AA, Do R, Sankaran VG, Gazda HT. The Genetic Landscape of Diamond-Blackfan Anemia. Am J Hum Genet. 2018 12 06; 103(6):930-947. View abstract
  10. Shadur B, Asherie N, Newburger PE, Stepensky P. How we approach: Severe congenital neutropenia and myelofibrosis due to mutations in VPS45. Pediatr Blood Cancer. 2019 01; 66(1):e27473. View abstract
  11. Frazão JB, Colombo M, Simillion C, Bilican A, Keller I, Wüthrich D, Zhu Z, Okoniewski MJ, Bruggmann R, Condino-Neto A, Newburger PE. Gene expression in chronic granulomatous disease and interferon-? receptor-deficient cells treated in vitro with interferon-?. J Cell Biochem. 2019 03; 120(3):4321-4332. View abstract
  12. van Beers EJ, van Straaten S, Morton DH, Barcellini W, Eber SW, Glader B, Yaish HM, Chonat S, Kwiatkowski JL, Rothman JA, Sharma M, Neufeld EJ, Sheth S, Despotovic JM, Kollmar N, Pospíšilová D, Knoll CM, Kuo K, Pastore YD, Thompson AA, Newburger PE, Ravindranath Y, Wang WC, Wlodarski MW, Wang H, Holzhauer S, Breakey VR, Verhovsek M, Kunz J, McNaull MA, Rose MJ, Bradeen HA, Addonizio K, Li A, Al-Sayegh H, London WB, Grace RF. Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study. Haematologica. 2019 02; 104(2):e51-e53. View abstract
  13. Grace RF, Bianchi P, van Beers EJ, Eber SW, Glader B, Yaish HM, Despotovic JM, Rothman JA, Sharma M, McNaull MM, Fermo E, Lezon-Geyda K, Morton DH, Neufeld EJ, Chonat S, Kollmar N, Knoll CM, Kuo K, Kwiatkowski JL, Pospíšilová D, Pastore YD, Thompson AA, Newburger PE, Ravindranath Y, Wang WC, Wlodarski MW, Wang H, Holzhauer S, Breakey VR, Kunz J, Sheth S, Rose MJ, Bradeen HA, Neu N, Guo D, Al-Sayegh H, London WB, Gallagher PG, Zanella A, Barcellini W. Clinical spectrum of pyruvate kinase deficiency: data from the Pyruvate Kinase Deficiency Natural History Study. Blood. 2018 05 17; 131(20):2183-2192. View abstract
  14. Newburger PE, Gross TG. "How I approach…"-A new series in Pediatric Blood & Cancer. Pediatr Blood Cancer. 2018 06; 65(6):e26994. View abstract
  15. Newburger PE. Comment on: Phenotypic Prenatal Diagnosis of Chronic Granulomatous Disease: A Useful Tool in the Absence of Molecular Diagnosis. Scand J Immunol. 2018 01; 87(1):57. View abstract
  16. Dale DC, Bolyard A, Marrero T, Makaryan V, Bonilla M, Link DC, Newburger P, Shimamura A, Boxer LA, Spiekerman C. Long-Term Effects of G-CSF Therapy in Cyclic Neutropenia. N Engl J Med. 2017 12 07; 377(23):2290-2292. View abstract
  17. Shah RK, Munson M, Wierenga KJ, Pokala HR, Newburger PE, Crawford D. A novel homozygous VPS45 p.P468L mutation leading to severe congenital neutropenia with myelofibrosis. Pediatr Blood Cancer. 2017 Sep; 64(9). View abstract
  18. Newburger PE, Opipari VP. Laurence A. Boxer, MD, 1940-2017. Pediatr Blood Cancer. 2017 06; 64(6). View abstract
  19. Newburger PE. Autoimmune and other acquired neutropenias. Hematology Am Soc Hematol Educ Program. 2016 Dec 02; 2016(1):38-42. View abstract
  20. Faller DV, Castaneda SA, Zhou D, Vedamony M, Newburger PE, White GL, Kosanke S, Plett PA, Orschell CM, Boosalis MS, Perrine SP. An oral HemokineTM, a-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo. Blood Cells Mol Dis. 2017 03; 63:1-8. View abstract
  21. Boucher MO, Chui DH, Woda BA, Newburger PE. Mild Microcytic Anemia in an Infant with a Compound Heterozygosity for Hb C (HBB: c.19G?>?A) and Hb Osu Christiansborg (HBB: c.157G?>?A). Hemoglobin. 2016 Jun; 40(3):208-9. View abstract
  22. Jhunjhunwala S, Alvarez D, Aresta-DaSilva S, Tang K, Tang BC, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. Frontline Science: Splenic progenitors aid in maintaining high neutrophil numbers at sites of sterile chronic inflammation. J Leukoc Biol. 2016 08; 100(2):253-60. View abstract
  23. Schmitz-Abe K, Ciesielski SJ, Schmidt PJ, Campagna DR, Rahimov F, Schilke BA, Cuijpers M, Rieneck K, Lausen B, Linenberger ML, Sendamarai AK, Guo C, Hofmann I, Newburger PE, Matthews D, Shimamura A, Snijders PJ, Towne MC, Niemeyer CM, Watson HG, Dziegiel MH, Heeney MM, May A, Bottomley SS, Swinkels DW, Markianos K, Craig EA, Fleming MD. Congenital sideroblastic anemia due to mutations in the mitochondrial HSP70 homologue HSPA9. Blood. 2015 Dec 17; 126(25):2734-8. View abstract
  24. Jhunjhunwala S, Aresta-DaSilva S, Tang K, Alvarez D, Webber MJ, Tang BC, Lavin DM, Veiseh O, Doloff JC, Bose S, Vegas A, Ma M, Sahay G, Chiu A, Bader A, Langan E, Siebert S, Li J, Greiner DL, Newburger PE, von Andrian UH, Langer R, Anderson DG. Neutrophil Responses to Sterile Implant Materials. PLoS One. 2015; 10(9):e0137550. View abstract
  25. Frazão JB, Thain A, Zhu Z, Luengo M, Condino-Neto A, Newburger PE. Regulation of CYBB Gene Expression in Human Phagocytes by a Distant Upstream NF-?B Binding Site. J Cell Biochem. 2015 Sep; 116(9):2008-17. View abstract
  26. Lipton JM, Newburger PE. In memoriam: Robert J. Arceci. Pediatr Blood Cancer. 2015 Aug; 62(8):iii. View abstract
  27. Makaryan V, Zeidler C, Bolyard AA, Skokowa J, Rodger E, Kelley ML, Boxer LA, Bonilla MA, Newburger PE, Shimamura A, Zhu B, Rosenberg PS, Link DC, Welte K, Dale DC. The diversity of mutations and clinical outcomes for ELANE-associated neutropenia. Curr Opin Hematol. 2015 Jan; 22(1):3-11. View abstract
  28. Boxer LA, Bolyard AA, Kelley ML, Marrero TM, Phan L, Bond JM, Newburger PE, Dale DC. Use of granulocyte colony-stimulating factor during pregnancy in women with chronic neutropenia. Obstet Gynecol. 2015 Jan; 125(1):197-203. View abstract
  29. Conti F, Aragão Filho WC, Prando C, Deswarte C, Hubeau M, Newburger PE, Casanova JL, Bustamante J, Condino-Neto A. Phagocyte nicotinamide adenine dinucleotide phosphate oxidase activity in patients with inherited IFN-?R1 or IFN-?R2 deficiency. J Allergy Clin Immunol. 2015 May; 135(5):1393-5.e1. View abstract
  30. Zhang X, Weissman SM, Newburger PE. Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells. RNA Biol. 2014; 11(6):777-87. View abstract
  31. Zhao H, Zhang X, Frazão JB, Condino-Neto A, Newburger PE. HOX antisense lincRNA HOXA-AS2 is an apoptosis repressor in all trans retinoic acid treated NB4 promyelocytic leukemia cells. J Cell Biochem. 2013 Oct; 114(10):2375-83. View abstract
  32. Newburger PE, Dale DC. Evaluation and management of patients with isolated neutropenia. Semin Hematol. 2013 Jul; 50(3):198-206. View abstract
  33. Landowski M, O'Donohue MF, Buros C, Ghazvinian R, Montel-Lehry N, Vlachos A, Sieff CA, Newburger PE, Niewiadomska E, Matysiak M, Glader B, Atsidaftos E, Lipton JM, Beggs AH, Gleizes PE, Gazda HT. Novel deletion of RPL15 identified by array-comparative genomic hybridization in Diamond-Blackfan anemia. Hum Genet. 2013 Nov; 132(11):1265-74. View abstract
  34. Usmani GN, Woda BA, Newburger PE. Advances in understanding the pathogenesis of HLH. Br J Haematol. 2013 Jun; 161(5):609-22. View abstract
  35. Gazda HT, Preti M, Sheen MR, O'Donohue MF, Vlachos A, Davies SM, Kattamis A, Doherty L, Landowski M, Buros C, Ghazvinian R, Sieff CA, Newburger PE, Niewiadomska E, Matysiak M, Glader B, Atsidaftos E, Lipton JM, Gleizes PE, Beggs AH. Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia. Hum Mutat. 2012 Jul; 33(7):1037-44. View abstract
  36. de Oliveira-Junior EB, Bustamante J, Newburger PE, Condino-Neto A. The human NADPH oxidase: primary and secondary defects impairing the respiratory burst function and the microbicidal ability of phagocytes. Scand J Immunol. 2011 May; 73(5):420-7. View abstract
  37. Bustamante J, Arias AA, Vogt G, Picard C, Galicia LB, Prando C, Grant AV, Marchal CC, Hubeau M, Chapgier A, de Beaucoudrey L, Puel A, Feinberg J, Valinetz E, Jannière L, Besse C, Boland A, Brisseau JM, Blanche S, Lortholary O, Fieschi C, Emile JF, Boisson-Dupuis S, Al-Muhsen S, Woda B, Newburger PE, Condino-Neto A, Dinauer MC, Abel L, Casanova JL. Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease. Nat Immunol. 2011 Mar; 12(3):213-21. View abstract
  38. Chang TY, Jaffray J, Woda B, Newburger PE, Usmani GN. Hemophagocytic lymphohistiocytosis with MUNC13-4 gene mutation or reduced natural killer cell function prior to onset of childhood leukemia. Pediatr Blood Cancer. 2011 May; 56(5):856-8. View abstract
  39. Newburger PE, Pindyck TN, Zhu Z, Bolyard AA, Aprikyan AA, Dale DC, Smith GD, Boxer LA. Cyclic neutropenia and severe congenital neutropenia in patients with a shared ELANE mutation and paternal haplotype: evidence for phenotype determination by modifying genes. Pediatr Blood Cancer. 2010 Aug; 55(2):314-7. View abstract
  40. Li JM, Newburger PE, Gounis MJ, Dargon P, Zhang X, Messina LM. Local arterial nanoparticle delivery of siRNA for NOX2 knockdown to prevent restenosis in an atherosclerotic rat model. Gene Ther. 2010 Oct; 17(10):1279-87. View abstract
  41. Rosenberg PS, Zeidler C, Bolyard AA, Alter BP, Bonilla MA, Boxer LA, Dror Y, Kinsey S, Link DC, Newburger PE, Shimamura A, Welte K, Dale DC. Stable long-term risk of leukaemia in patients with severe congenital neutropenia maintained on G-CSF therapy. Br J Haematol. 2010 Jul; 150(2):196-9. View abstract
  42. Yasukochi Y, Maruyama O, Mahajan MC, Padden C, Euskirchen GM, Schulz V, Hirakawa H, Kuhara S, Pan XH, Newburger PE, Snyder M, Weissman SM. X chromosome-wide analyses of genomic DNA methylation states and gene expression in male and female neutrophils. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3704-9. View abstract
  43. Doherty L, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Clinton C, Schneider HE, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Glader B, Arceci RJ, Farrar JE, Atsidaftos E, Lipton JM, Gleizes PE, Gazda HT. Ribosomal protein genes RPS10 and RPS26 are commonly mutated in Diamond-Blackfan anemia. Am J Hum Genet. 2010 Feb 12; 86(2):222-8. View abstract
  44. Errante PR, Prando C, Bustamante J, Aragão Filho WC, Pereira PV, Rehder J, Casanova JL, Newburger P, Condino Neto A. Comment on "Impaired priming and activation of the neutrophil NADPH oxidase in patients with IRAK4 or NEMO deficiency". J Immunol. 2009 Sep 15; 183(6):3559. View abstract
  45. Mahajan MC, Karmakar S, Newburger PE, Krause DS, Weissman SM. Dynamics of alpha-globin locus chromatin structure and gene expression during erythroid differentiation of human CD34(+) cells in culture. Exp Hematol. 2009 Oct; 37(10):1143-1156.e3. View abstract
  46. Rao VK, Price S, Perkins K, Aldridge P, Tretler J, Davis J, Dale JK, Gill F, Hartman KR, Stork LC, Gnarra DJ, Krishnamurti L, Newburger PE, Puck J, Fleisher T. Use of rituximab for refractory cytopenias associated with autoimmune lymphoproliferative syndrome (ALPS). Pediatr Blood Cancer. 2009 Jul; 52(7):847-52. View abstract
  47. Newburger PE. Cyclic neutropenia in animals. Am J Hematol. 2009 Apr; 84(4):258; author reply 258. View abstract
  48. Zhang X, Lian Z, Padden C, Gerstein MB, Rozowsky J, Snyder M, Gingeras TR, Kapranov P, Weissman SM, Newburger PE. A myelopoiesis-associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster. Blood. 2009 Mar 12; 113(11):2526-34. View abstract
  49. Gazda HT, Sheen MR, Vlachos A, Choesmel V, O'Donohue MF, Schneider H, Darras N, Hasman C, Sieff CA, Newburger PE, Ball SE, Niewiadomska E, Matysiak M, Zaucha JM, Glader B, Niemeyer C, Meerpohl JJ, Atsidaftos E, Lipton JM, Gleizes PE, Beggs AH. Ribosomal protein L5 and L11 mutations are associated with cleft palate and abnormal thumbs in Diamond-Blackfan anemia patients. Am J Hum Genet. 2008 Dec; 83(6):769-80. View abstract
  50. Wang JP, Bowen GN, Padden C, Cerny A, Finberg RW, Newburger PE, Kurt-Jones EA. Toll-like receptor-mediated activation of neutrophils by influenza A virus. Blood. 2008 Sep 01; 112(5):2028-34. View abstract
  51. Luengo-Blanco M, Prando C, Bustamante J, Aragão-Filho WC, Pereira PV, Rehder J, Padden C, Casanova JL, Newburger PE, Condino-Neto A. Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes. Blood. 2008 Aug 15; 112(4):1453-60. View abstract
  52. Newburger PE, Castle VP. The American Society of Pediatric Hematology/Oncology distinguished career award goes to Laurence A. Boxer, MD. Pediatr Blood Cancer. 2008 Jun; 50(6):1121-2. View abstract
  53. Newburger PE. IL6 to the rescue. Blood. 2008 Apr 15; 111(8):3914-5. View abstract
  54. Hochberg JC, Miron PM, Hay BN, Woda BA, Wang SA, Richert-Przygonska M, Aprikyan AA, Newburger PE. Mosaic tetraploidy and transient GFI1 mutation in a patient with severe chronic neutropenia. Pediatr Blood Cancer. 2008 Mar; 50(3):630-2. View abstract
  55. Marçal LE, Dias-da-Motta PM, Rehder J, Mamoni RL, Blotta MH, Whitney CB, Newburger PE, Costa FF, Saad ST, Condino-Neto A. Up-regulation of NADPH oxidase components and increased production of interferon-gamma by leukocytes from sickle cell disease patients. Am J Hematol. 2008 Jan; 83(1):41-5. View abstract
  56. Rosenberg PS, Alter BP, Link DC, Stein S, Rodger E, Bolyard AA, Aprikyan AA, Bonilla MA, Dror Y, Kannourakis G, Newburger PE, Boxer LA, Dale DC. Neutrophil elastase mutations and risk of leukaemia in severe congenital neutropenia. Br J Haematol. 2008 Jan; 140(2):210-3. View abstract
  57. Boxer LA, Newburger PE. A molecular classification of congenital neutropenia syndromes. Pediatr Blood Cancer. 2007 Oct 15; 49(5):609-14. View abstract
  58. Birney E, Stamatoyannopoulos JA, Dutta A, Guigó R, Gingeras TR, Margulies EH, Weng Z, Snyder M, Dermitzakis ET, Thurman RE, Kuehn MS, Taylor CM, Neph S, Koch CM, Asthana S, Malhotra A, Adzhubei I, Greenbaum JA, Andrews RM, Flicek P, Boyle PJ, Cao H, Carter NP, Clelland GK, Davis S, Day N, Dhami P, Dillon SC, Dorschner MO, Fiegler H, Giresi PG, Goldy J, Hawrylycz M, Haydock A, Humbert R, James KD, Johnson BE, Johnson EM, Frum TT, Rosenzweig ER, Karnani N, Lee K, Lefebvre GC, Navas PA, Neri F, Parker SC, Sabo PJ, Sandstrom R, Shafer A, Vetrie D, Weaver M, Wilcox S, Yu M, Collins FS, Dekker J, Lieb JD, Tullius TD, Crawford GE, Sunyaev S, Noble WS, Dunham I, Denoeud F, Reymond A, Kapranov P, Rozowsky J, Zheng D, Castelo R, Frankish A, Harrow J, Ghosh S, Sandelin A, Hofacker IL, Baertsch R, Keefe D, Dike S, Cheng J, Hirsch HA, Sekinger EA, Lagarde J, Abril JF, Shahab A, Flamm C, Fried C, Hackermüller J, Hertel J, Lindemeyer M, Missal K, Tanzer A, Washietl S, Korbel J, Emanuelsson O, Pedersen JS, Holroyd N, Taylor R, Swarbreck D, Matthews N, Dickson MC, Thomas DJ, Weirauch MT, Gilbert J, Drenkow J, Bell I, Zhao X, Srinivasan KG, Sung WK, Ooi HS, Chiu KP, Foissac S, Alioto T, Brent M, Pachter L, Tress ML, Valencia A, Choo SW, Choo CY, Ucla C, Manzano C, Wyss C, Cheung E, Clark TG, Brown JB, Ganesh M, Patel S, Tammana H, Chrast J, Henrichsen CN, Kai C, Kawai J, Nagalakshmi U, Wu J, Lian Z, Lian J, Newburger P, Zhang X, Bickel P, Mattick JS, Carninci P, Hayashizaki Y, Weissman S, Hubbard T, Myers RM, Rogers J, Stadler PF, Lowe TM, Wei CL, Ruan Y, Struhl K, Gerstein M, Antonarakis SE, Fu Y, Green ED, Karaöz U, Siepel A, Taylor J, Liefer LA, Wetterstrand KA, Good PJ, Feingold EA, Guyer MS, Cooper GM, Asimenos G, Dewey CN, Hou M, Nikolaev S, Montoya-Burgos JI, Löytynoja A, Whelan S, Pardi F, Massingham T, Huang H, Zhang NR, Holmes I, Mullikin JC, Ureta-Vidal A, Paten B, Seringhaus M, Church D, Rosenbloom K, Kent WJ, Stone EA, Batzoglou S, Goldman N, Hardison RC, Haussler D, Miller W, Sidow A, Trinklein ND, Zhang ZD, Barrera L, Stuart R, King DC, Ameur A, Enroth S, Bieda MC, Kim J, Bhinge AA, Jiang N, Liu J, Yao F, Vega VB, Lee CW, Ng P, Shahab A, Yang A, Moqtaderi Z, Zhu Z, Xu X, Squazzo S, Oberley MJ, Inman D, Singer MA, Richmond TA, Munn KJ, Rada-Iglesias A, Wallerman O, Komorowski J, Fowler JC, Couttet P, Bruce AW, Dovey OM, Ellis PD, Langford CF, Nix DA, Euskirchen G, Hartman S, Urban AE, Kraus P, Van Calcar S, Heintzman N, Kim TH, Wang K, Qu C, Hon G, Luna R, Glass CK, Rosenfeld MG, Aldred SF, Cooper SJ, Halees A, Lin JM, Shulha HP, Zhang X, Xu M, Haidar JN, Yu Y, Ruan Y, Iyer VR, Green RD, Wadelius C, Farnham PJ, Ren B, Harte RA, Hinrichs AS, Trumbower H, Clawson H, Hillman-Jackson J, Zweig AS, Smith K, Thakkapallayil A, Barber G, Kuhn RM, Karolchik D, Armengol L, Bird CP, de Bakker PI, Kern AD, Lopez-Bigas N, Martin JD, Stranger BE, Woodroffe A, Davydov E, Dimas A, Eyras E, Hallgrímsdóttir IB, Huppert J, Zody MC, Abecasis GR, Estivill X, Bouffard GG, Guan X, Hansen NF, Idol JR, Maduro VV, Maskeri B, McDowell JC, Park M, Thomas PJ, Young AC, Blakesley RW, Muzny DM, Sodergren E, Wheeler DA, Worley KC, Jiang H, Weinstock GM, Gibbs RA, Graves T, Fulton R, Mardis ER, Wilson RK, Clamp M, Cuff J, Gnerre S, Jaffe DB, Chang JL, Lindblad-Toh K, Lander ES, Koriabine M, Nefedov M, Osoegawa K, Yoshinaga Y, Zhu B, de Jong PJ. Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature. 2007 Jun 14; 447(7146):799-816. View abstract
  59. Li JM, Zhang X, Nelson PR, Odgren PR, Nelson JD, Vasiliu C, Park J, Morris M, Lian J, Cutler BS, Newburger PE. Temporal evolution of gene expression in rat carotid artery following balloon angioplasty. J Cell Biochem. 2007 May 15; 101(2):399-410. View abstract
  60. Hattori H, Zhang X, Jia Y, Subramanian KK, Jo H, Loison F, Newburger PE, Luo HR. RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells. Blood. 2007 Jul 15; 110(2):640-50. View abstract
  61. Nakayama Y, Stabach P, Maher SE, Mahajan MC, Masiar P, Liao C, Zhang X, Ye ZJ, Tuck D, Bothwell AL, Newburger PE, Weissman SM. A limited number of genes are involved in the differentiation of germinal center B cells. J Cell Biochem. 2006 Dec 01; 99(5):1308-25. View abstract
  62. Fan L, Jones SN, Padden C, Shen Q, Newburger PE. Nuclease sensitive element binding protein 1 gene disruption results in early embryonic lethality. J Cell Biochem. 2006 Sep 01; 99(1):140-5. View abstract
  63. Rezk S, Wheelock L, Fletcher JA, Oliveira AM, Keuker CP, Newburger PE, Xu B, Woda BA, Miron PM. Acute lymphocytic leukemia with eosinophilia and unusual karyotype. Leuk Lymphoma. 2006 Jun; 47(6):1176-9. View abstract
  64. Shen Q, Fan L, Newburger PE. Nuclease sensitive element binding protein 1 associates with the selenocysteine insertion sequence and functions in mammalian selenoprotein translation. J Cell Physiol. 2006 Jun; 207(3):775-83. View abstract
  65. Agudelo-Flórez P, Prando-Andrade CC, López JA, Costa-Carvalho BT, Quezada A, Espinosa FJ, de Souza Paiva MA, Roxo P, Grumach A, Jacob CA, Carneiro-Sampaio MM, Newburger PE, Condino-Neto A. Chronic granulomatous disease in Latin American patients: clinical spectrum and molecular genetics. Pediatr Blood Cancer. 2006 Feb; 46(2):243-52. View abstract
  66. Newburger PE. Disorders of neutrophil number and function. Hematology Am Soc Hematol Educ Program. 2006; 104-10. View abstract
  67. Rozowsky J, Wu J, Lian Z, Nagalakshmi U, Korbel JO, Kapranov P, Zheng D, Dyke S, Newburger P, Miller P, Gingeras TR, Weissman S, Gerstein M, Snyder M. Novel transcribed regions in the human genome. Cold Spring Harb Symp Quant Biol. 2006; 71:111-6. View abstract
  68. Almeida AC, Rehder J, Severino SD, Martins-Filho J, Newburger PE, Condino-Neto A. The effect of IFN-gamma and TNF-alpha on the NADPH oxidase system of human colostrum macrophages, blood monocytes, and THP-1 cells. J Interferon Cytokine Res. 2005 Sep; 25(9):540-6. View abstract
  69. Newburger PE. Hematology and oncology. Curr Opin Pediatr. 2005 Feb; 17(1):1-2. View abstract
  70. Kurt-Jones EA, Belko J, Yu C, Newburger PE, Wang J, Chan M, Knipe DM, Finberg RW. The role of toll-like receptors in herpes simplex infection in neonates. J Infect Dis. 2005 Mar 01; 191(5):746-8. View abstract
  71. Kluger Y, Lian Z, Zhang X, Newburger PE, Weissman SM. A panorama of lineage-specific transcription in hematopoiesis. Bioessays. 2004 Dec; 26(12):1276-87. View abstract
  72. Marçal LE, Rehder J, Newburger PE, Condino-Neto A. Superoxide release and cellular gluthatione peroxidase activity in leukocytes from children with persistent asthma. Braz J Med Biol Res. 2004 Nov; 37(11):1607-13. View abstract
  73. Zhan Y, He D, Newburger PE, Zhou GW. p47(phox) PX domain of NADPH oxidase targets cell membrane via moesin-mediated association with the actin cytoskeleton. J Cell Biochem. 2004 Jul 01; 92(4):795-809. View abstract
  74. Kluger Y, Tuck DP, Chang JT, Nakayama Y, Poddar R, Kohya N, Lian Z, Ben Nasr A, Halaban HR, Krause DS, Zhang X, Newburger PE, Weissman SM. Lineage specificity of gene expression patterns. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6508-13. View abstract
  75. Agudelo-Flórez P, Costa-Carvalho BT, López JA, Redher J, Newburger PE, Olalla-Saad ST, Condino-Neto A. Association of glucose-6-phosphate dehydrogenase deficiency and X-linked chronic granulomatous disease in a child with anemia and recurrent infections. Am J Hematol. 2004 Mar; 75(3):151-6. View abstract
  76. Newburger PE. Hematology and oncology. Curr Opin Pediatr. 2004 Feb; 16(1):1-2. View abstract
  77. Lopez JA, Newburger PE, Condino-Neto A. The effect of IFN-gamma and TNF-alpha on the eosinophilic differentiation and NADPH oxidase activation of human HL-60 clone 15 cells. J Interferon Cytokine Res. 2003 Dec; 23(12):737-44. View abstract
  78. Zhang X, Kluger Y, Nakayama Y, Poddar R, Whitney C, DeTora A, Weissman SM, Newburger PE. Gene expression in mature neutrophils: early responses to inflammatory stimuli. J Leukoc Biol. 2004 Feb; 75(2):358-72. View abstract
  79. Wallace J, Zhou Y, Usmani GN, Reardon M, Newburger P, Woda B, Pihan G. BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays. Leukemia. 2003 Jul; 17(7):1411-3. View abstract
  80. Wallace J, Zhou Y, Usmani GN, Reardon M, Newburger P, Woda B, Pihan G. BARCODE-ALL: accelerated and cost-effective genetic risk stratification in acute leukemia using spectrally addressable liquid bead microarrays. Leukemia. 2003 Jul; 17(7):1404-10. View abstract
  81. Tsukahara Y, Lian Z, Zhang X, Whitney C, Kluger Y, Tuck D, Yamaga S, Nakayama Y, Weissman SM, Newburger PE. Gene expression in human neutrophils during activation and priming by bacterial lipopolysaccharide. J Cell Biochem. 2003 Jul 01; 89(4):848-61. View abstract
  82. Newburger PE. Hematology and oncology. Curr Opin Pediatr. 2003 Feb; 15(1):1-2. View abstract
  83. Lian Z, Kluger Y, Greenbaum DS, Tuck D, Gerstein M, Berliner N, Weissman SM, Newburger PE. Genomic and proteomic analysis of the myeloid differentiation program: global analysis of gene expression during induced differentiation in the MPRO cell line. Blood. 2002 Nov 01; 100(9):3209-20. View abstract
  84. Kurt-Jones EA, Mandell L, Whitney C, Padgett A, Gosselin K, Newburger PE, Finberg RW. Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils. Blood. 2002 Sep 01; 100(5):1860-8. View abstract
  85. Newburger PE, Elfenbein DS, Boxer LA. Adolescents with cancer: access to clinical trials and age-appropriate care. Curr Opin Pediatr. 2002 Feb; 14(1):1-4. View abstract
  86. Noack D, Heyworth PG, Newburger PE, Cross AR. An unusual intronic mutation in the CYBB gene giving rise to chronic granulomatous disease. Biochim Biophys Acta. 2001 Sep 28; 1537(2):125-31. View abstract
  87. Lian Z, Wang L, Yamaga S, Bonds W, Beazer-Barclay Y, Kluger Y, Gerstein M, Newburger PE, Berliner N, Weissman SM. Genomic and proteomic analysis of the myeloid differentiation program. Blood. 2001 Aug 01; 98(3):513-24. View abstract
  88. Subrahmanyam YV, Yamaga S, Prashar Y, Lee HH, Hoe NP, Kluger Y, Gerstein M, Goguen JD, Newburger PE, Weissman SM. RNA expression patterns change dramatically in human neutrophils exposed to bacteria. Blood. 2001 Apr 15; 97(8):2457-68. View abstract
  89. Noack D, Rae J, Cross AR, Ellis BA, Newburger PE, Curnutte JT, Heyworth PG. Autosomal recessive chronic granulomatous disease caused by defects in NCF-1, the gene encoding the phagocyte p47-phox: mutations not arising in the NCF-1 pseudogenes. Blood. 2001 Jan 01; 97(1):305-11. View abstract
  90. Condino-Neto A, Newburger PE. Interferon-gamma improves splicing efficiency of CYBB gene transcripts in an interferon-responsive variant of chronic granulomatous disease due to a splice site consensus region mutation. Blood. 2000 Jun 01; 95(11):3548-54. View abstract
  91. Wu R, Shen Q, Newburger PE. Recognition and binding of the human selenocysteine insertion sequence by nucleolin. J Cell Biochem. 2000 Apr; 77(3):507-16. View abstract
  92. Newburger PE, Subrahmanyam YV, Weissman SM. Global analysis of neutrophil gene expression. Curr Opin Hematol. 2000 Jan; 7(1):16-20. View abstract
  93. Newburger PE. Hematology and oncology. Curr Opin Pediatr. 1999 Feb; 11(1):31-2. View abstract
  94. Subrahmanyam YV, Baskaran N, Newburger PE, Weissman SM. A modified method for the display of 3'-end restriction fragments of cDNAs: molecular profiling of gene expression in neutrophils. Methods Enzymol. 1999; 303:272-97. View abstract
  95. Condino-Neto A, Newburger PE. NADPH oxidase activity and cytochrome b558 content of human Epstein-Barr-virus-transformed B lymphocytes correlate with expression of genes encoding components of the oxidase system. Arch Biochem Biophys. 1998 Dec 15; 360(2):158-64. View abstract
  96. Cooper CL, Newburger PE. Differential expression of Id genes in multipotent myeloid progenitor cells: Id-1 is induced by early-and late-acting cytokines while Id-2 is selectively induced by cytokines that drive terminal granulocytic differentiation. J Cell Biochem. 1998 Nov 01; 71(2):277-85. View abstract
  97. Condino-Neto A, Whitney C, Newburger PE. Dexamethasone but not indomethacin inhibits human phagocyte nicotinamide adenine dinucleotide phosphate oxidase activity by down-regulating expression of genes encoding oxidase components. J Immunol. 1998 Nov 01; 161(9):4960-7. View abstract
  98. Rae J, Newburger PE, Dinauer MC, Noack D, Hopkins PJ, Kuruto R, Curnutte JT. X-Linked chronic granulomatous disease: mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase. Am J Hum Genet. 1998 Jun; 62(6):1320-31. View abstract
  99. Inanami O, Johnson JL, McAdara JK, Benna JE, Faust LR, Newburger PE, Babior BM. Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304. J Biol Chem. 1998 Apr 17; 273(16):9539-43. View abstract
  100. Shen Q, Wu R, Leonard JL, Newburger PE. Identification and molecular cloning of a human selenocysteine insertion sequence-binding protein. A bifunctional role for DNA-binding protein B. J Biol Chem. 1998 Mar 06; 273(10):5443-6. View abstract
  101. Newburger PE. Hematology and oncology. Curr Opin Pediatr. 1998 Feb; 10(1):47-8. View abstract
  102. Becker PS, Li Z, Potselueva T, Madri JA, Newburger PE, Berliner N. Laminin promotes differentiation of NB4 promyelocytic leukemia cells with all-trans retinoic acid. Blood. 1996 Jul 01; 88(1):261-7. View abstract
  103. Quesenberry PJ, Iscove NN, Cooper C, Brady G, Newburger PE, Stein GS, Stein JS, Reddy GP, Pearson-White S. Expression of basic helix-loop-helix transcription factors in explant hematopoietic progenitors. J Cell Biochem. 1996 Jun 01; 61(3):478-88. View abstract
  104. Leonard JL, Leonard DM, Shen Q, Farwell AP, Newburger PE. Selenium-regulated translation control of heterologous gene expression: normal function of selenocysteine-substituted gene products. J Cell Biochem. 1996 Jun 01; 61(3):410-9. View abstract
  105. Chanock SJ, Faust LR, Barrett D, Christensen B, Newburger PE, Babior BM. Partial reconstitution of the respiratory burst oxidase in lymphoblastoid B cell lines lacking p67-phox after transfection with an expression vector containing wild-type and mutant p67 -phox cDNAs: Deletions of the carboxy and amino terminal residues of p67-phox are not required for activity. Exp Hematol. 1996 Mar; 24(4):531-6. View abstract
  106. Newburger PE, Quesenberry PJ. Umbilical cord blood as a new and promising source of unrelated-donor hematopoietic stem cells for transplantation. Curr Opin Pediatr. 1996 Feb; 8(1):29-32. View abstract
  107. Shen Q, McQuilkin PA, Newburger PE. RNA-binding proteins that specifically recognize the selenocysteine insertion sequence of human cellular glutathione peroxidase mRNA. J Biol Chem. 1995 Dec 22; 270(51):30448-52. View abstract
  108. Shen Q, Leonard JL, Newburger PE. Structure and function of the selenium translation element in the 3'-untranslated region of human cellular glutathione peroxidase mRNA. RNA. 1995 Jul; 1(5):519-25. View abstract
  109. Woodman RC, Newburger PE, Anklesaria P, Erickson RW, Rae J, Cohen MS, Curnutte JT. A new X-linked variant of chronic granulomatous disease characterized by the existence of a normal clone of respiratory burst-competent phagocytic cells. Blood. 1995 Jan 01; 85(1):231-41. View abstract
  110. Shen Q, Chada S, Whitney C, Newburger PE. Regulation of the human cellular glutathione peroxidase gene during in vitro myeloid and monocytic differentiation. Blood. 1994 Dec 01; 84(11):3902-8. View abstract
  111. Newburger PE, Malawista SE, Dinauer MC, Gelbart T, Woodman RC, Chada S, Shen Q, van Blaricom G, Quie PG, Curnutte JT. Chronic granulomatous disease and glutathione peroxidase deficiency, revisited. Blood. 1994 Dec 01; 84(11):3861-9. View abstract
  112. Newburger PE, Skalnik DG, Hopkins PJ, Eklund EA, Curnutte JT. Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558. J Clin Invest. 1994 Sep; 94(3):1205-11. View abstract
  113. Shen Q, Townes PL, Padden C, Newburger PE. An in-frame trinucleotide repeat in the coding region of the human cellular glutathione peroxidase (GPX1) gene: in vivo polymorphism and in vitro instability. Genomics. 1994 Sep 01; 23(1):292-4. View abstract
  114. Maly FE, Schuerer-Maly CC, Quilliam L, Cochrane CG, Newburger PE, Curnutte JT, Gifford M, Dinauer MC. Restitution of superoxide generation in autosomal cytochrome-negative chronic granulomatous disease (A22(0) CGD)-derived B lymphocyte cell lines by transfection with p22phax cDNA. J Exp Med. 1993 Dec 01; 178(6):2047-53. View abstract
  115. Baker RD, Baker SS, LaRosa K, Whitney C, Newburger PE. Selenium regulation of glutathione peroxidase in human hepatoma cell line Hep3B. Arch Biochem Biophys. 1993 Jul; 304(1):53-7. View abstract
  116. Bernardo J, Brennan L, Brink HF, Ortiz MF, Newburger PE, Simons ER. Chemotactic peptide-induced cytoplasmic pH changes in incubated human monocytes. J Leukoc Biol. 1993 Jun; 53(6):673-8. View abstract
  117. Shen Q, Chu FF, Newburger PE. Sequences in the 3'-untranslated region of the human cellular glutathione peroxidase gene are necessary and sufficient for selenocysteine incorporation at the UGA codon. J Biol Chem. 1993 May 25; 268(15):11463-9. View abstract
  118. Pise CA, Newburger PE, Holland CA. Human immunodeficiency virus type 1-infected HL-60 cells are capable of both monocytic and granulocytic differentiation. J Gen Virol. 1992 Dec; 73 ( Pt 12):3257-61. View abstract
  119. Chanock SJ, Faust LR, Barrett D, Bizal C, Maly FE, Newburger PE, Ruedi JM, Smith RM, Babior BM. O2- production by B lymphocytes lacking the respiratory burst oxidase subunit p47phox after transfection with an expression vector containing a p47phox cDNA. Proc Natl Acad Sci U S A. 1992 Nov 01; 89(21):10174-7. View abstract
  120. Schapiro BL, Newburger PE, Klempner MS, Dinauer MC. Chronic granulomatous disease presenting in a 69-year-old man. N Engl J Med. 1991 Dec 19; 325(25):1786-90. View abstract
  121. Newburger PE, Dai Q, Whitney C. In vitro regulation of human phagocyte cytochrome b heavy and light chain gene expression by bacterial lipopolysaccharide and recombinant human cytokines. J Biol Chem. 1991 Aug 25; 266(24):16171-7. View abstract
  122. Ezekowitz RA, Sieff CA, Dinauer MC, Nathan DG, Orkin SH, Newburger PE. Restoration of phagocyte function by interferon-gamma in X-linked chronic granulomatous disease occurs at the level of a progenitor cell. Blood. 1990 Dec 15; 76(12):2443-8. View abstract
  123. Ryan TC, Weil GJ, Newburger PE, Haugland R, Simons ER. Measurement of superoxide release in the phagovacuoles of immune complex-stimulated human neutrophils. J Immunol Methods. 1990 Jul 03; 130(2):223-33. View abstract
  124. Bernardo J, Newburger PE, Brennan L, Brink HF, Bresnick SA, Weil G, Simons ER. Simultaneous flow cytometric measurements of cytoplasmic Ca++ and membrane potential changes upon FMLP exposure as HL-60 cells mature into granulocytes: using [Ca++]in as an indicator of granulocyte maturity. J Leukoc Biol. 1990 Mar; 47(3):265-74. View abstract
  125. Chada S, Le Beau MM, Casey L, Newburger PE. Isolation and chromosomal localization of the human glutathione peroxidase gene. Genomics. 1990 Feb; 6(2):268-71. View abstract
  126. Barker KA, Newburger PE. Relationships between the cell cycle and the expression of c-myc and transferrin receptor genes during induced myeloid differentiation. Exp Cell Res. 1990 Jan; 186(1):1-5. View abstract
  127. Chada S, Whitney C, Newburger PE. Post-transcriptional regulation of glutathione peroxidase gene expression by selenium in the HL-60 human myeloid cell line. Blood. 1989 Nov 15; 74(7):2535-41. View abstract
  128. Holland CA, Chada S, Wright J, Whitney C, Harigaya K, Greenberger JS, Newburger PE. Differentiation of human hematopoietic cells increases expression of a gene transferred by a retroviral vector. J Leukoc Biol. 1989 Sep; 46(3):221-9. View abstract
  129. Holland CA, Rothstein L, Sakakeeny MA, Anklesaria P, Griffin JD, Harigaya K, Newburger PE, Greenberger JS. Infection of hematopoietic and stromal cells in human continuous bone marrow cultures by a retroviral vector containing the neomycin resistance gene. Acta Haematol. 1989; 82(3):136-43. View abstract
  130. Ezekowitz RA, Newburger PE. New perspectives in chronic granulomatous disease. J Clin Immunol. 1988 Nov; 8(6):419-25. View abstract
  131. Ezekowitz RA, Dinauer MC, Jaffe HS, Orkin SH, Newburger PE. Partial correction of the phagocyte defect in patients with X-linked chronic granulomatous disease by subcutaneous interferon gamma. N Engl J Med. 1988 Jul 21; 319(3):146-51. View abstract
  132. Newburger PE, Ezekowitz RA, Whitney C, Wright J, Orkin SH. Induction of phagocyte cytochrome b heavy chain gene expression by interferon gamma. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5215-9. View abstract
  133. Barker KA, Orkin SH, Newburger PE. Expression of the X-CGD gene during induced differentiation of myeloid leukemia cell line HL-60. Mol Cell Biol. 1988 Jul; 8(7):2804-10. View abstract
  134. Newburger PE, Ezekowitz RA. Cellular and molecular effects of recombinant interferon gamma in chronic granulomatous disease. Hematol Oncol Clin North Am. 1988 Jun; 2(2):267-76. View abstract
  135. Nitzberg MC, Newburger PE, Raymond J. Marrow donors and international cooperation. Lancet. 1988 Jan 16; 1(8577):117-8. View abstract
  136. Ezekowitz RA, Orkin SH, Newburger PE. Recombinant interferon gamma augments phagocyte superoxide production and X-chronic granulomatous disease gene expression in X-linked variant chronic granulomatous disease. J Clin Invest. 1987 Oct; 80(4):1009-16. View abstract
  137. Rothenberg ME, Caulfield JP, Austen KF, Hein A, Edmiston K, Newburger PE, Stevens RL. Biochemical and morphological characterization of basophilic leukocytes from two patients with myelogenous leukemia. J Immunol. 1987 Apr 15; 138(8):2616-25. View abstract
  138. Speier C, Newburger PE. Changes in superoxide dismutase, catalase, and the glutathione cycle during induced myeloid differentiation. Arch Biochem Biophys. 1986 Dec; 251(2):551-7. View abstract
  139. Beard CJ, Key L, Newburger PE, Ezekowitz RA, Arceci R, Miller B, Proto P, Ryan T, Anast C, Simons ER. Neutrophil defect associated with malignant infantile osteopetrosis. J Lab Clin Med. 1986 Nov; 108(5):498-505. View abstract
  140. Newburger PE, Luscinskas FW, Ryan T, Beard CJ, Wright J, Platt OS, Simons ER, Tauber AI. Variant chronic granulomatous disease: modulation of the neutrophil defect by severe infection. Blood. 1986 Oct; 68(4):914-9. View abstract
  141. Royer-Pokora B, Kunkel LM, Monaco AP, Goff SC, Newburger PE, Baehner RL, Cole FS, Curnutte JT, Orkin SH. Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location. Nature. 1986 Jul 3-9; 322(6074):32-8. View abstract
  142. Kazazian HH, Orkin SH, Boehm CD, Goff SC, Wong C, Dowling CE, Newburger PE, Knowlton RG, Brown V, Donis-Keller H. Characterization of a spontaneous mutation to a beta-thalassemia allele. Am J Hum Genet. 1986 Jun; 38(6):860-7. View abstract
  143. Takahashi K, Newburger PE, Cohen HJ. Glutathione peroxidase protein. Absence in selenium deficiency states and correlation with enzymatic activity. J Clin Invest. 1986 Apr; 77(4):1402-4. View abstract
  144. Clegg HW, Ephros M, Newburger PE. Pseudomonas cepacia pneumonia in chronic granulomatous disease. Pediatr Infect Dis. 1986 Jan-Feb; 5(1):111. View abstract
  145. Greenberger JS, FitzGerald TJ, Rothstein L, Pierce J, Sakakeeny MA, Weichselbaum RR, Naparstek E, Newburger P, Griffin J, Bast R, et al. Long-term culture of human granulocytes and granulocyte progenitor cells. Prog Clin Biol Res. 1986; 211:159-85. View abstract
  146. Royer-Pokora B, Kunkel LM, Monaco AP, Goff SC, Newburger PE, Baehner RL, Cole FS, Curnutte JT, Orkin SH. Cloning the gene for the inherited disorder chronic granulomatous disease on the basis of its chromosomal location. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 1:177-83. View abstract
  147. Speier C, Baker SS, Newburger PE. Relationships between in vitro selenium supply, glutathione peroxidase activity, and phagocytic function in the HL-60 human myeloid cell line. J Biol Chem. 1985 Jul 25; 260(15):8951-5. View abstract
  148. Leb L, Beatson P, Fortier N, Newburger PE, Snyder LM. Modulation of mononuclear phagocyte cytotoxicity by alpha-tocopherol (vitamin E). J Leukoc Biol. 1985 Apr; 37(4):449-59. View abstract
  149. Newburger PE, Speier C, Stock JL, Perrine SP, Greenberger JS. Chediak-Higashi syndrome: studies in long-term bone marrow culture. Exp Hematol. 1985 Feb; 13(2):117-22. View abstract
  150. Newburger PE, Speier C, Borregaard N, Walsh CE, Whitin JC, Simons ER. Development of the superoxide-generating system during differentiation of the HL-60 human promyelocytic leukemia cell line. J Biol Chem. 1984 Mar 25; 259(6):3771-6. View abstract
  151. Szymanski IO, Teno RA, Gandhi JG, Newburger PE. Studies on low-dose hydroxyethyl starch leukapheresis. Rate of elimination of HES in vivo and function of the harvested granulocytes in vitro. Vox Sang. 1984; 47(5):325-9. View abstract
  152. Shurin SB, Cohen HJ, Whitin JC, Newburger PE. Impaired granulocyte superoxide production and prolongation of the respiratory burst due to a low-affinity NADPH-dependent oxidase. Blood. 1983 Sep; 62(3):564-71. View abstract
  153. Newburger PE, Robinson JM, Pryzwansky KB, Rosoff PM, Greenberger JS, Tauber AI. Human neutrophil dysfunction with giant granules and defective activation of the respiratory burst. Blood. 1983 Jun; 61(6):1247-57. View abstract
  154. Seger RA, Tiefenauer L, Matsunaga T, Wildfeuer A, Newburger PE. Chronic granulomatous disease due to granulocytes with abnormal NADPH oxidase activity and deficient cytochrome-b. Blood. 1983 Mar; 61(3):423-8. View abstract
  155. Newburger PE, Novak TJ, McCaffrey RP. Eosinophilic cytoplasmic inclusions in fetal leukocytes: are Auer bodies a recapitulation of fetal morphology? Blood. 1983 Mar; 61(3):593-5. View abstract
  156. Rappeport JM, Newburger PE, Goldblum RM, Goldman AS, Nathan DG, Parkman R. Allogeneic bone marrow transplantation for chronic granulomatous disease. J Pediatr. 1982 Dec; 101(6):952-5. View abstract
  157. Cohen HJ, Chovaniec ME, Wilson MK, Newburger PE. Con-A-stimulated superoxide production by granulocytes: reversible activation of NADPH oxidase. Blood. 1982 Nov; 60(5):1188-94. View abstract
  158. Newburger PE, Tauber AI. Heterogeneous pathways of oxidizing radical production in human neutrophils and the HL-60 cell line. Pediatr Res. 1982 Oct; 16(10):856-60. View abstract
  159. Newburger PE. Superoxide generation by human fetal granulocytes. Pediatr Res. 1982 May; 16(5):373-6. View abstract
  160. Cohen HJ, Newburger PE, Chovaniec ME, Whitin JC, Simons ER. Opsonized zymosan-stimulated granulocytes-activation and activity of the superoxide-generating system and membrane potential changes. Blood. 1981 Nov; 58(5):975-82. View abstract
  161. Greenberg HM, Newburger PE, Parker LM, Novak T, Greenberger JS. Human granulocytes generated in continuous bone marrow culture are physiologically normal. Blood. 1981 Oct; 58(4):724-32. View abstract
  162. Button LN, DeWolf WC, Newburger PE, Jacobson MS, Kevy SV. The effects of irradiation on blood components. Transfusion. 1981 Jul-Aug; 21(4):419-26. View abstract
  163. Newburger PE, Baker RD, Hansen SL, Duncan RA, Greenberger JS. Functionally deficient differentiation of HL-60 promyelocytic leukemia cells induced by phorbol myristate acetate. Cancer Res. 1981 May; 41(5):1861-5. View abstract
  164. Newburger PE, Latt SA, Pesando JM, Gustashaw K, Powers M, Chaganti RS, O'Reilly RJ. Leukemia relapse in donor cells after allogeneic bone-marrow transplantation. N Engl J Med. 1981 Mar 19; 304(12):712-4. View abstract
  165. Newburger PE, Sallan SE. Chronic pain: principles of management. J Pediatr. 1981 Feb; 98(2):180-9. View abstract
  166. Greenberg HM, Parker LM, Newburger PE, Said J, Cohen GI, Greenberger JS. Corticosteroid dependence of continuous hemopoiesis in vitro with murine or human bone marrow. Haematol Blood Transfus. 1981; 26:289-93. View abstract
  167. Greenberger JS, Newburger PE, Sakakeeny M. Phorbol myristate acetate stimulates macrophage differentiation and replication and alters granulopoiesis and leukemogenesis in long-term bone marrow cultures. Blood. 1980 Sep; 56(3):368-79. View abstract
  168. Newburger PE, Kruskall MS, Rappeport JM, Robinson SH, Chovaniec ME, Cohen HJ. Chronic granulomatous disease. Expression of the metabolic defect by in vitro culture of bone marrow progenitors. J Clin Invest. 1980 Sep; 66(3):599-602. View abstract
  169. Cohen HJ, Newburger PE, Chovaniec ME. NAD(P)H-dependent superoxide production by phagocytic vesicles from guinea pig and human granulocytes. J Biol Chem. 1980 Jul 25; 255(14):6584-8. View abstract
  170. Newburger PE, Pagano JS, Greenberger JS, Karpas A, Cohen HJ. Dissociation of opsonized particle phagocytosis and respiratory burst activity in an Epstein-Barr virus-infected myeloid cell line. J Cell Biol. 1980 Jun; 85(3):549-57. View abstract
  171. Rappeport JM, Parkman R, Newburger P, Camitta BM, Chusid MJ. Correction of infantile agranulocytosis (Kostmann's syndrome) by allogeneic bone marrow transplantation. Am J Med. 1980 Apr; 68(4):605-9. View abstract
  172. Greenberger JS, Newburger PE, Lipton JM, Moloney WC, Sakakeeny MA, Jackson PL. Virus and cell requirements for Friend virus granulocytic leukemogenesis in long-term bone marrow cultures of NIH swiss [N:NIH(S)] mice. J Natl Cancer Inst. 1980 Apr; 64(4):867-78. View abstract
  173. Newburger PE, Chovaniec ME, Cohen HJ. Activity and activation of the granulocyte superoxide-generating system. Blood. 1980 Jan; 55(1):85-92. View abstract
  174. Newburger PE, Chovaniec ME, Greenberger JS, Cohen HJ. Functional changes in human leukemic cell line HL-60. A model for myeloid differentiation. J Cell Biol. 1979 Aug; 82(2):315-22. View abstract
  175. Newburger PE, Latt SA. Improved fluorescent staining of interphase nuclei for prenatal diagnosis. Lancet. 1979 May 26; 1(8126):1144. View abstract
  176. Boal DK, Newburger PE, Teele RL. Esophagitis induced by combined radiation and adriamycin. AJR Am J Roentgenol. 1979 Apr; 132(4):567-70. View abstract
  177. Newburger PE, Cohen HJ, Rothchild SB, Hobbins JC, Malawista SE, Mahoney MJ. Prenatal diagnosis of chronic granulomatous disease. N Engl J Med. 1979 Jan 25; 300(4):178-81. View abstract
  178. Greenberger JS, Newburger PE, Karpas A, Moloney WC. Constitutive and inducible granulocyte-macrophage functions in mouse, rat, and human myeloid leukemia-derived continuous tissue culture lines. Cancer Res. 1978 Oct; 38(10):3340-8. View abstract
  179. Newburger PE, Cassady JR, Jaffe N. Esophagitis due to adriamycin and radiation therapy for childhood malignancy. Cancer. 1978 Aug; 42(2):417-23. View abstract
  180. Hamaoka T, Newburger PE, Katz DH, Benacerraf B. Hapten-specific IgE antibody responses in mice. 3. Establishment of parameters for generation of helper T cell function regulating the primary and secondary responses of IgE and IgG B lymphocytes. J Immunol. 1974 Sep; 113(3):958-73. View abstract
  181. Katz DH, Hamaoka T, Newburger PE, Benacerraf B. Hapten-specific IgE antibody responses in mice. IV. Evidence for distinctive sensitivities of IgE and IgG B lymphocytes to the regulatory influence of T cells. J Immunol. 1974 Sep; 113(3):974-83. View abstract
  182. Newburger PE, Hamaoka T, Katz DH. Potentiation of helper T cell function in IgE antibody responses by bacterial lipolysaccharide (LPS). J Immunol. 1974 Sep; 113(3):824-9. View abstract
  183. Dorf ME, Newburger PE, Hamaoka T, Katz DH, Benacerraf B. Characterization of an immune response gene in mice controlling IgE and IgM antibody responses to ragweed pollen extract and its 2,4-dinitrophenylated derivative. Eur J Immunol. 1974 May; 4(5):346-9. View abstract