Testing & Diagnosis for Von Willebrand Disease in Children

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Contact the Boston Hemophilia Center

How is von Willebrand disease diagnosed?

If your child’s doctor suspects von Willebrand disease (vWD), she will ask about any family history of bleeding or bleeding disorders and will conduct a physical exam for signs of bleeding, liver disease or anemia.

Your doctor will recommend certain tests to confirm the diagnosis. These tests are ordered by a hematologist (a doctor with specialized training in treating blood disorders). They are meant to measure the levels of von Willebrand factor in the blood, as well as the amount of other important factors and how well the body’s clotting mechanisms are working. These tests may include:

  • von Willebrand factor antigen
  • von Willebrand Ristocetin cofactor activity
  • factor VIII activity
  • von Willebrand multimers

Your doctor may order these tests more than once to confirm the diagnosis and determine the proper course of treatment for vWD.

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