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Parkes Weber syndrome (PWS) affects different children in different ways. One child may have a mild form with a small capillary malformation and one hand or foot slightly larger than the other. Another child may have a capillary malformation that runs from her chest down her leg, lots of swelling, heart problems and one limb that is much larger than the other.
Some possible symptoms of PWS include:
In many patients, PWS is caused by a mutation in a gene called RASA1. This mutation can run in families. A patient with PWS can pass this mutation on to his or her children. However, not every patient with PWS has a RASA1 mutation.
No known food, medication or activity during pregnancy can cause PWS.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”