Mixed Gonadal Dysgenesis Pediatric Research and Clinical Trials

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Contact the Department of Urology

  • 1-617-355-7796

Research & Innovation

Years ago, babies born with disorders of sexual differentiation (DSD) like mixed gonadal dysgenesis (MGD) were routinely "assigned" a gender by their physicians, and underwent treatment to match that assignment. Today, decision-making is much more individualized and is done in close consultation with the family.

Today, the medical approach to treating children with DSDs has changed dramatically, thanks in large part to national advocacy groups formed by adult patients.

The Gender Management Service (GeMS) Clinic at Boston Children's Hospital encourages parents to take part in the decision-making process of how to treat their child’s DSD. We don’t rush families to make important decision, so parents and doctors have adequate tome to chose the best treatment for the child.

The goals of treatment for MGD are focused on these factors:

  • How are we doing raising these children as male or female?
  • What factors help us best to predict success?
  • What are the most important forms of support we can provide these children and their parents?
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”
- Sandra L. Fenwick, President and CEO

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