Leber's Optic Atrophy in Children

LIke ThisLIke ThisLIke ThisLIke ThisLIke This

Overview

Leber's Hereditary Optic Neuropathy, or LHON, causes a painless loss of central vision in people with the condition when they’re between 12 and 30 years old. It’s associated with a mutation in mitochondrial DNA, which is inherited only from a child’s mother.

  • LHON was the first human disease associated with a mutation in mitochondrial DNA.
  • Both eyes are affected at the same time.
  • Males will not pass the gene to any of their children, but females with the mutation will pass it to all of their children, regardless of whether they are sons or daughters.

Leber's optic atrophy

The future of pediatrics will be forged by thinking differently, breaking paradigms and joining together in a shared vision of tackling the toughest challenges before us.”
- Sandra L. Fenwick, President and CEO

Boston Children's Hospital 300 Longwood Avenue, Boston, MA 02115 617-355-6000 | 800-355-7944

Close