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There are no known factors or conditions that would make your child more or less likely to develop gliomatosis cerebri.
Symptoms might come on slowly and subtly, or they might appear more abruptly. Each child may experience symptoms differently, and the most common include:
The symptoms gliomatosis cerebri may resemble other conditions or medical problems. Always consult your child's physician for a diagnosis.
The World Health Organization classification scheme includes 4 grades of glioma.
However, since only a fraction of gliomatosis cerebri tumors are biopsied, it can be difficult to conclusively assign a grade to them.
That said, they usually progress like grade IV glioblastoma multiforme tumors. These are the most aggressive kind of astrocytic tumor, and they usually have the following characteristics:
These tumors are aggressive, and will invade normal brain tissue. They are also likely to spread outside the central nervous system to other parts of the body.
A variety of chemotherapeutic regimens have been evaluated in the treatment of newly diagnosed high-grade gliomas.
Boston Children's Hospital and Dana-Farber Cancer Institute are conducting many research studies that will help clinicians better understand and treat gliomatosis cerebri. For more information on our current research initiatives, see the Brain Tumor Program.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”