Diamond Blackfan Anemia

What is Diamond-Blackfan anemia (DBA)?

Diamond-Blackfan anemia (DBA) is a rare blood disorder that occurs when the bone marrow fails to make red blood cells, which are essential for carrying oxygen from the lungs to all the other parts of the body. First described in 1938 by Boston Children's Hospital doctors Kenneth Blackfan, MD, and Louis Diamond, MD (who later established Dana-Farber/Boston Children's Cancer and Blood Disorders Center), DBA is a potentially life-threatening condition that can cause severe anemia and other abnormalities.

How we approach Diamond-Blackfan anemia at Dana-Farber/Boston Children's

Children and teens with Diamond-Blackfan anemia (DBA) are treated at Dana-Farber/Boston Children's Cancer and Blood Disorders Center through our Bone Marrow Failure Program, recognized as one of the nation's best pediatric treatment and research programs for bone marrow failure and related conditions. Our patients have access to advanced treatments and diagnosis, including DNA mutation identification and ongoing clinical trials investigating new treatments. Dana-Farber/Boston Children's is also home to one of the largest and most experienced pediatric stem cell transplant centers in the world. Stem cell (bone marrow) transplant is currently the only cure for DBA.

Find in-depth information on Diamond-Blackfan anemia on the Dana-Farber/Boston Children's website, including:

  • What causes Diamond-Blackfan anemia?
  • What are the symptoms of Diamond-Blackfan anemia?
  • How is Diamond-Blackfan anemia diagnosed?
  • How is Diamond-Blackfan anemia treated?
  • What is the latest research on Diamond-Blackfan anemia?
  • What is the long-term outlook for children with Diamond-Blackfan anemia?