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Because symptoms of CLOVES syndrome can be subtle and hard to notice right away (or obvious and causing clear problems in day-to-day life), it’s critical to seek a diagnosis from an experienced vascular anomalies specialist.
To diagnose CLOVES syndrome, doctors will usually combine these steps:
CLOVES is so rare and still not a widely known disorder that an ultrasound is not a foolproof way to detect it. A clinical exam must be performed after birth.
Children with CLOVES syndrome are often mistakenly diagnosed as having other disorders that cause overgrowth of the blood vessels and abnormalities in certain parts of the body, such as:
The main difference between these conditions and CLOVES is that CLOVES causes a combination of vascular, skin and limb/torso abnormalities and truncal/spinal abnormalities (like fatty masses, scoliosis or tethered cord).
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”