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An atrioventricular canal defect or AV canal is a combination of several closely-associated heart problems that result in a large defect in the center of the heart. Also known as atrioventricular septal defect or endocardial cushion defect, the condition is congenital, which means it is present at birth, and occurs in two out of every 10,000 newborns. It is often associated with Down syndrome.
When the heart is properly divided, blood from the lungs does not mix with blood from the body; however, with an AV canal, blood moves freely among the four heart chambers. If left untreated, AV canal can cause many problems involving the heart and lungs.
Like many congenital heart conditions, AV canal defect isn’t actually a single defect but rather a group of closely-associated defects in various combinations and with varying degrees of severity:
In addition, there are other associated heart defects such as patent ductus arteriosus, transposition of the great arteries, unbalanced AV canal defects and aortic arch hypoplasia.
At Boston Children’s Hospital our Cardiac Surgery team treats some of the most complex pediatric heart conditions in the world, with overall success rates exceeding 98 percent — among the highest in the nation among large pediatric cardiac centers. In particular, the methods used to repair an AV canal defect have improved greatly in the past two decades, and the operation has a high likelihood of success.
The Boston Children’s Hospital Heart Center deals with the most complex AV canals, which often include children operated on at other centers. We are committed to constantly refining and improving our techniques and procedures.
Children with unbalanced AV canal, traditionally treated as single ventricle defect, are now being considered for biventricular repair. This is achieved using innovative techniques, developed in Boston Children’s Complex Biventricular Repair Program, and refined with 3-D printed hearts in the lab, to ensure the repair is durable throughout a lifetime.
We are grateful to have been ranked #1 on U.S. News & World Report's list of the best children's hospitals in the nation for the third year in a row, an honor we could not have achieved without the patients and families who inspire us to do our very best for them. Thanks to you, Boston Children's is a place where we can write the greatest children's stories ever told.”