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The Science

This section is intended to provide information for families, physicians, genetic counselors, and researchers who are interested in learning more about the research in the Beggs’ Laboratory. We have broken this information down into several categories, …

Sponsors

We appreciate the assistance provided by the organizations listed below. Without them, our work would not be possible. Please follow the links to their websites if you want to learn more about their work as well as how to provide support.   AFMTELETHON   …

Nemaline Animation

      nemaline-animation Beggs Laboratory | Nemaline Animation … Nemaline Animation …

Contact Us

  Margaret Stefater-Richards margaret.stefater@childrens.harvard.edu Twitter: @MStefRichMDPhD contact-us Stefater-Richards Lab | Contact Us Contact the Stefater-Richards Lab at Boston Children's Hospital. … Contact …

Epidural Steroid Injections for Radiculopathy and/or Back Pain in Children and Adolescents: A Retrospective Cohort Study with Prospective Follow-Up

  Epidural steroid injections are commonly performed for adults with spinal pain and/or radiculopathy. The primary aim of this study was to examine safety and provisional outcomes of pediatric epidural steroid injections. This study showed that: ESIs can …

Immediate Rescue Designs in Pediatric Analgesic Trials

  Designing analgesic clinical trials in pediatrics requires a balance between scientific, ethical, and practical concerns. A previous consensus group recommended immediate rescue designs using opioid sparing as a surrogate measure of analgesic efficacy. …

Pain in Children with Juvenile Idiopathic Arthritis

  Juvenile Idiopathic Arthritis (JIA) is the most common cause of non-infectious joint inflammation in children.  In this study, we show that JIA is associated with widespread sensitivity to painful mechanical and thermal stimuli, even in the absence of …

Lab Alumni

  C= Clinical-Oriented Research | L= Lab-Oriented Research Joseph Kim, MA: Research Assistant (2012-2016) | C Joe received his MA in Medical Sciences from Boston University.  His research interests included medications used in anesthesia, animal models, …

Neosaxitoxin for Prolonged Local Anesthesia

  Researchers have long sought a safe, long-acting, local anesthetic that would be clinically useful for patients during or after surgery or with any painful condition that is amenable to nerve blockade. Such a drug or combination could potentially …

Outcomes, Clinical Effectiveness, of Gabapentin and Oxcarbazepine for Chronic Neuropathic Pain in Children and Adolescents

  Clinical trials evaluating the efficacy and effectiveness of analgesic medications and pain interventions pose ethical and scientific challenges when studied in the pediatric population particularly when the interventions are invasive and due to the …

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