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Pediatric High-grade Gliomas: Research Reveals Effective Targeting

Pediatric High-grade Gliomas: Research Reveals Effective Targeting BOSTON, MA [March 26, 2025] — Pediatric high-grade gliomas , particularly H3K27M diffuse midline gliomas (DMG) , are aggressive malignant brain tumors with a poor prognosis. Previous …
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Partnering Diet and Intestinal Microbes to Protect Against GI Disease

Partnering Diet and Intestinal Microbes to Protect Against GI Disease BOSTON, MA [March 27, 2025] — Despite being an everyday necessity, nutrition is something of a black box. We know that many plant-based foods are good for us, but we don’t always know …
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Funded Partners

Funded Partners Updated as of April 17, 2025. Expanding and Diversifying the Children’s Mental and Behavioral Health Workforce Funding in this area aims to facilitate creative community partnership efforts that expand and diversify the pipeline of trained …
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Infantile Spasms: Speeding Referrals for All Infants

Read more: "Infantile Spasms: Speeding Referrals for All Infants."

Infantile Spasms: Speeding Referrals for All Infants Boston Children’s researchers develop teaching module to improve health equity for infantile spasms BOSTON, MA [Jan. 19, 2024] — Infantile epileptic spasms syndrome (IESS), often called infantile spasms …
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How the Brain Wakes Us from Daydreams

Read more: "How the brain wakes us from daydreams."

How the Brain Wakes Us from Daydreams Researchers at Boston Children’s Hospital discover that activity in the dentate gyrus keeps us focused on our environment when our mind wanders BOSTON, MA [March 13, 2024] — When we daydream, we must be able to snap …
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Ancient DNA Reveals Origin of Racial, Ethnic Disparity in a Childhood Cancer

Read more: "Ancient DNA reveals origin of racial/ethnic disparity in a childhood cancer."

Ancient DNA Reveals Origin of Racial, Ethnic Disparity in a Childhood Cancer Researchers identify a genetic variant that explains why more Hispanic/Latino children are diagnosed with acute lymphoblastic leukemia (ALL) and uncover the mutation’s Indigenous …
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Historically Redlined Areas See More Modern-day Gun Violence

Read more: "Historically redlined areas see more modern-day gun violence."

Historically Redlined Areas See More Modern-day Gun Violence New research from Boston Children’s Hospital suggests that areas of U.S. cities graded as 'hazardous' in the 1930s are nearly six times more likely to have non-suicide firearm fatalities today …
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Brain Wiring Predicted Adolescents’ Emotional Health During COVID-19 Pandemic

Read more: "Brain wiring predicted adolescents’ emotional health during COVID-19 pandemic."

Brain Wiring Predicted Adolescents’ Emotional Health During COVID-19 Pandemic Organization of specific brain circuits was associated with increased emotional vulnerability or increased resilience BOSTON, MA [May 16, 2024] — The COVID-19 pandemic was …
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Discovery, Optimization of a Promising Vaccine Adjuvant

Read more: "From ‘hit to vial’: Discovery and optimization of a promising vaccine adjuvant."

Discovery, Optimization of a Promising Vaccine Adjuvant BOSTON, MA [July 3, 2024] — Many vaccines are only partially effective, have waning efficacy, or do not work well in the very young or the very old. For more than a decade, Ofer Levy, MD, PhD , and …
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Study Reveals Critical Role of C1q in Neuronal Function, Aging

Read more: "New study reveals critical role of C1q protein in neuronal function and aging."

Study Reveals Critical Role of C1q in Neuronal Function, Aging Highlights how temporally regulated neuroimmune interactions can impact critical intraneuronal functions and raises questions about the additional roles of glial and immune interactions in …