Lauren Collen, MD
Gastroenterologist, Division of Gastroenterology, Hepatology and Nutrition
Assistant Professor of Pediatrics, Harvard Medical School
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Lauren Collen, MD
Gastroenterologist, Division of Gastroenterology, Hepatology and Nutrition
Assistant Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Undergraduate School
Rensselaer Polytechnic Institute
Troy
NY
Medical School
University of Massachusetts Medical School
Worcester
MA
Residency
Boston Combined Residency Program
Boston
MA
Fellowship
Boston Children's Hospital
Boston
MA
Fellowship
Advanced Inflammatory Bowel Disease Fellowship
Boston Children's Hospital
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Gastroenterology)
Professional History
Dr. Collen’s clinical and research interests lie in the care of patients with inflammatory bowel disease (IBD), including Crohn’s disease and ulcerative colitis. She has special interest in understanding and treating patients with very early onset IBD (VEOIBD), defined as disease onset at less than 6 years of age, and those with disease that has been refractory to conventional therapies. Dr. Collen completed an Advanced Fellowship in Pediatric Inflammatory Bowel Disease at Boston Children’s Hospital and is a recipient of a Crohn’s and Colitis Foundation Research Fellows Award. Her research interests are in understanding the underlying pathways that drive disease in her IBD patients with the ultimate goal of advancing options for personalized medicine.
Approach to Care
Every patient with IBD has a unique experience of their disease and responses to therapy. Dr. Collen’s philosophy is to take the time to understand her patients’ experiences before making treatment recommendations that take into account her patients’ symptoms and goals.
Publications
Discordance between a deep learning model and clinical-grade variant pathogenicity classification in a rare disease cohort. View Abstract
A progranulin variant causing childhood interstitial lung disease responsive to anti-TNF-a biologic therapy. View Abstract
Effectiveness and Safety of Adalimumab in Patients With Very Early-Onset Inflammatory Bowel Disease: A Retrospective Study on Behalf of the Porto Inflammatory Bowel Disease Working Group of European Society for Pediatric Gastroenterology Hepatology and Nutrition. View Abstract
Efficacy and Safety of Anti-Tumor Necrosis Factor Alpha in Very Early Onset Inflammatory Bowel Disease. View Abstract
Breaking Down Barriers: Epithelial Contributors to Monogenic IBD Pathogenesis. View Abstract
Discordance between a deep learning model and clinical-grade variant pathogenicity classification in a rare disease cohort. View Abstract
Response to Letter to the Editor: "Failure Rate of Antitumor Necrosis Factor Alpha Biologics in Very Early Onset Inflammatory Bowel Disease". View Abstract
Catalyzing change: Implementing standardised reporting in monogenic inflammatory bowel disease research. View Abstract
Clinical Remission of Severe Crohn's Disease with Empagliflozin Monotherapy in a Pediatric Patient with Glycogen Storage Disease Type 1b. View Abstract
Rapid Clinical Remission With Upadacitinib in a Pediatric Patient With Refractory Crohn's Disease. View Abstract
Pancreatitis-Associated Medication Use in Hospitalized Pediatric and Young Adult Patients With Acute Pancreatitis. View Abstract
Vertebral Compression Fractures in Very Early Onset Inflammatory Bowel Disease. View Abstract
Clinical Phenotypes and Outcomes in Monogenic Versus Non-monogenic Very Early Onset Inflammatory Bowel Disease. View Abstract
Inflammatory Bowel Disease and Cardiovascular Diseases. View Abstract
Cytotoxic T Lymphocyte Antigen 4 Haploinsufficiency Presenting As Refractory Celiac-Like Disease: Case Report. View Abstract
An occurrence of apnea, bradycardia, and desaturation events resulting in a delay of discharge in late preterm and full term infants. View Abstract
Economics of Home Monitoring for Apnea in Late Preterm Infants. View Abstract
Diagnostic Evaluation and Home Monitor Use in Late Preterm to Term Infants With Apnea, Bradycardia, and Desaturations. View Abstract
The nondietary determinants of vitamin D status in pediatric inflammatory bowel disease. View Abstract
The vitamin D status in inflammatory bowel disease. View Abstract
Continuous feedings of fortified human milk lead to nutrient losses of fat, calcium and phosphorous. View Abstract