David Hoytema van Konijnenburg completed his MD, PhD at Utrecht University, with PhD research in Immunology completed in the Van Wijk lab in Utrecht and in the Mucida lab at The Rockefeller University in New York, NY. His research focused on intestinal T cells in gut homeostasis, inflammation and infection using a combination of techniques including live imaging. Next, Dr. Hoytema completed pediatrics residency at Boston Childrens Hospital and Harvard Medical School / Boston Medical Center and Boston University (Boston Combined Residency Program in Pediatrics) concurrent with research in the Kirchhausen lab and Zon lab at Harvard Medical School, where he studied the function of tissue-resident immune cells in the skin and tumors. After pediatrics residency, Dr. Hoytema completed Allergy and Immunology fellowship at Boston Children's Hospital and Harvard Medical School.

Dr. Hoytema is a current Allergy and Immunology Attending Physician at Boston Children's Hospital and Instructor at Harvard Medical School, working in Nigrovic lab and Zanoni lab on tissue-resident immune cells in the lung. Clinically, Dr. Hoytema is especially passionate about providing care for patients with immune dysregulation syndromes or immunodeficiency, with a focus on immunogenetics and research-based clinical care for patients with rare diseases of the immune system. Dr. Hoytema has won several awards for his research and clinical work. He is a member of the MIDAS program for immune dysregulation, the Immunogenetics program and the program for Interstitial Lung Diseases. Dr. Hoytema is Board Certified in Pediatrics and Allergy/Immunology.