Christopher B. Weldon, MD, PhD

Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine; Pediatric Surgeon, Department of Surgery
Associate Professor of Surgery, Harvard Medical School
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 Christopher B. Weldon, MD, PhD

Christopher B. Weldon, MD, PhD

Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine; Pediatric Surgeon, Department of Surgery
Associate Professor of Surgery, Harvard Medical School
Education
Undergraduate School
University of Notre Dame
1991
Notre Dame
IN
Medical School
Tulane University School of Medicine
1995 & 2001
New Orleans
LA
Internship
Tulane University School of Medicine
195
New Orleans
LA
Residency
Tulane University School of Medicine
1996
New Orleans
LA
Fellowship
Critical Care
Tulane University
2003
New Orleans
LA
Fellowship
Boston Children's Hospital
2004
Boston
MA
Certifications
American Board of Surgery (General)
American Board of Surgery (Pediatric Surgery)
American Board of Surgery (Surgical Critical Care)

Publications

Poverty, race, ethnicity, and survival in pediatric nonmetastatic osteosarcoma: a Children's Oncology Group report. View Abstract
Pediatric Adrenocortical Carcinoma: The Nuts and Bolts of Diagnosis and Treatment and Avenues for Future Discovery. View Abstract
Long-term outcomes among survivors of childhood osteosarcoma: A report from the Childhood Cancer Survivor Study (CCSS). View Abstract
Surgical management of liver tumors. View Abstract
Correction to: Positron emission tomography in the diagnosis and management of primary pediatric lung tumors. View Abstract
Positron emission tomography in the diagnosis and management of primary pediatric lung tumors. View Abstract
Critical elements of pediatric liver cancer surgery. View Abstract
A single-institution pediatric and young adult interventional oncology collaborative: Novel therapeutic options for relapsed/refractory solid tumors. View Abstract
Lymphatic Embolization for the Management of Post-operative Chyle Leaks Following Solid Tumor Resection in Pediatric Patients. View Abstract
Cumulative burden of late, major surgical intervention in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study (CCSS) cohort. View Abstract
An aptamer-based depot system for sustained release of small molecule therapeutics. View Abstract
Vincristine/irinotecan/temsirolimus upfront window treatment of high-risk hepatoblastoma: A report from the Children's Oncology Group AHEP0731 Study Committee. View Abstract
Perioperative hypertension and anesthetic management in patients undergoing resection of neuroblastoma. View Abstract
Late Health Outcomes Among Survivors of Wilms Tumor Diagnosed Over Three Decades: A Report From the Childhood Cancer Survivor Study. View Abstract
Outcomes of children with well-differentiated fetal hepatoblastoma treated with surgery only: Report from Children's Oncology Group Trial, AHEP0731. View Abstract
Case 2-2022: An Adolescent Male in Cardiac Arrest 3 Days After Liver Transplantation for End-Stage Liver Disease. View Abstract
What Are Risk Factors for and Outcomes of Late Amputation After Treatment for Lower Extremity Sarcoma: A Childhood Cancer Survivor Study Report. View Abstract
68 Ga-DOTATATE PET and functional imaging in pediatric pheochromocytoma and paraganglioma. View Abstract
Complications associated with totally implantable access ports in children less than 1 year of age. View Abstract
Doxorubicin in combination with cisplatin, 5-flourouracil, and vincristine is feasible and effective in unresectable hepatoblastoma: A Children's Oncology Group study. View Abstract
Interdisciplinary Management of Malignant Ovarian Tumors in the Pediatric and Adolescent Age Group. View Abstract
Late-onset kidney failure in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. View Abstract
Pancreatoblastoma in children: EXPeRT/PARTNER diagnostic and therapeutic recommendations. View Abstract
Sex-Specific Associations Between Chemotherapy, Chronic Conditions, and Neurocognitive Impairment in Acute Lymphoblastic Leukemia Survivors: A Report From the Childhood Cancer Survivor Study. View Abstract
Treatment of Pediatric Adrenocortical Carcinoma With Surgery, Retroperitoneal Lymph Node Dissection, and Chemotherapy: The Children's Oncology Group ARAR0332 Protocol. View Abstract
Neonatal Malignant Disorders: Germ Cell Tumors. View Abstract
Management of Adrenal Tumors in Pediatric Patients. View Abstract
Epidemiology of abdominal wall and groin hernia repairs in children. View Abstract
Opioid Prescription Patterns for Children Following Laparoscopic Appendectomy. View Abstract
Training in pediatric surgical critical care. View Abstract
The use of interval-compressed chemotherapy with the addition of vincristine, irinotecan, and temozolomide for pediatric patients with newly diagnosed desmoplastic small round cell tumor. View Abstract
Making the most of small samples: Optimization of tissue allocation of pediatric solid tumors for clinical and research use. View Abstract
Imaging features of pathologically proven pediatric splenic masses. View Abstract
Incidence of and risk factors for late cholecystectomy in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. View Abstract
Comparison of Military Health System Data Repository and American College of Surgeons National Surgical Quality Improvement Program-Pediatric. View Abstract
Late-onset anorectal disease and psychosocial impact in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study. View Abstract
Therapeutic Impact and Complications Associated with Surgical Lung Biopsy after Allogeneic Hematopoietic Stem Cell Transplantation in Children. View Abstract
Evaluation of the diagnostic biopsy approach for children with hepatoblastoma: A report from the children's oncology group AHEP 0731 liver tumor committee. View Abstract
Geographic distance to pediatric surgical care within the continental United States. View Abstract
Multicenter pre-operative assessment of pediatric ovarian malignancy. View Abstract
Clinical features and outcomes of spitzoid proliferations in children and adolescents. View Abstract
Time versus treatment: interpreting longitudinal data analysis of treprostinil. View Abstract
Nanoscale Bupivacaine Formulations To Enhance the Duration and Safety of Intravenous Regional Anesthesia. View Abstract
Temporal patterns in the risk of chronic health conditions in survivors of childhood cancer diagnosed 1970-99: a report from the Childhood Cancer Survivor Study cohort. View Abstract
Long-Term Risk of Venous Thromboembolism in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. View Abstract
Another point of view on 2017 PRETEXT: reply to Pariente et al. View Abstract
Incidence and risk factors for sepsis after childhood splenectomy. View Abstract
Pediatric pancreatic neoplasms: The time is nigh for collaboration across continents. View Abstract
Late Infection-Related Mortality in Asplenic Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. View Abstract
Testicular atrophy following inguinal hernia repair in children. View Abstract
Hernia recurrence following inguinal hernia repair in children. View Abstract
2017 PRETEXT: radiologic staging system for primary hepatic malignancies of childhood revised for the Paediatric Hepatic International Tumour Trial (PHITT). View Abstract
Characterization of Pulmonary Metastases in Children With Hepatoblastoma Treated on Children's Oncology Group Protocol AHEP0731 (The Treatment of Children With All Stages of Hepatoblastoma): A Report From the Children's Oncology Group. View Abstract
The role of thymectomy in the treatment of juvenile myasthenia gravis: a systematic review. View Abstract
Malignant glomus tumors of the head and neck in children and adults: Evaluation and management. View Abstract
Surgical Management of Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Pediatric and Wildtype GIST Clinic. View Abstract
Pediatric/"Wildtype" gastrointestinal stromal tumors. View Abstract
Safety and cost-effectiveness of port removal outside of the operating room among pediatric patients. View Abstract
Safety of peritoneal and pleural drain placement in pediatric stem cell transplant recipients with severe veno-occlusive disease. View Abstract
Molecular Subtypes of KIT/PDGFRA Wild-Type Gastrointestinal Stromal Tumors: A Report From the National Institutes of Health Gastrointestinal Stromal Tumor Clinic. View Abstract
Preoperative risk stratification of children with ovarian tumors. View Abstract
Poor adherence to staging guidelines for children with malignant ovarian tumors. View Abstract
Diagnostic Impact of Peritoneal Fluid Cytology in the Setting of Pediatric Uterine Adnexal Biopsy or Resection. View Abstract
Intestinal Obstruction in Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. View Abstract
Analysis of submitted abstracts for the American Academy of Pediatrics, Section on Surgery, National Conference (AAP SoSU). View Abstract
Sedation and analgesia in the ICU. View Abstract
Surgical consultation and intervention during pediatric hematopoietic stem cell transplantation. View Abstract
Comparison of plasmapheresis and intravenous immunoglobulin as maintenance therapies for juvenile myasthenia gravis. View Abstract
Factors associated with survival in patients who undergo peritoneal dialysis catheter placement following cardiac surgery. View Abstract
Characterizing peritoneal dialysis catheter use in pediatric patients after cardiac surgery. View Abstract
Fetal and neonatal germ cell tumors. View Abstract
Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha. View Abstract
Electrospun drug-eluting sutures for local anesthesia. View Abstract
Pediatric gastrointestinal stromal tumor. View Abstract
Adrenal cortical tumors in children: factors associated with poor outcome. View Abstract
Facilitators of quality breast cancer screening and diagnosis in an urban environment. View Abstract
Oncology Medical Home to address challenges in breast cancer care delivery. View Abstract
Barriers to implementing primary HER2 FISH testing. View Abstract
Prophylactic oophorectomy for patients with breast cancer with BRCA results. View Abstract
BRCA+ test result impact and timing on surgical treatment decisions for patients with breast cancer. View Abstract
Preoperative MDCT evaluation of congenital lung anomalies in children: comparison of axial, multiplanar, and 3D images. View Abstract
Nanotechnology for surgeons. View Abstract
ALK rearrangement in sickle cell trait-associated renal medullary carcinoma. View Abstract
Regulation of ERalpha-mediated transcription of Bcl-2 by PI3K-AKT crosstalk: implications for breast cancer cell survival. View Abstract
Primary lung tumors in children and adolescents: a 90-year experience. View Abstract
Adolescent gynecomastia: not only an obesity issue. View Abstract
Childhood pancreatic tumors: a single institution experience. View Abstract
In utero diagnosis of congenital pyloric atresia in a single twin using MRI and ultrasound. View Abstract
H-type rectovaginal fistula in a patient with bilateral single ectopic ureters. View Abstract
Reduced size liver transplantation from a donor supported by a Berlin Heart. View Abstract
Mortality of necrotizing enterocolitis expressed by birth weight categories. View Abstract
Outcomes after the Ladd procedure in patients with heterotaxy syndrome, congenital heart disease, and intestinal malrotation. View Abstract
Mesenteric lipoblastoma presenting as a segmental volvulus. View Abstract
Use of a distal arteriovenous fistula in a complex vascular reconstruction after resection of an osteosarcoma in a high-risk child. View Abstract
Proteomic analysis of tumor necrosis factor-alpha resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype. View Abstract
Hepatoblastoma presenting with focal nodular hyperplasia after treatment of neuroblastoma. View Abstract
A familial case of pleuropulmonary blastoma. View Abstract
Pediatric pulmonary tumors: primary and metastatic. View Abstract
Pediatric Pulmonary Tumors View Abstract
Congenital Esophageal Disorders View Abstract
A Familial Case of Pleuropulmonary Blastoma View Abstract
Surgical Aspects of Pediatric Oncology View Abstract
p38 mitogen-activated protein kinase stimulates estrogen-mediated transcription and proliferation through the phosphorylation and potentiation of the p160 coactivator glucocorticoid receptor-interacting protein 1. View Abstract
P38 mitogen-activated protein kinase stimulates estrogen-mediated transcription and proliferation through the phosphorylation and potentiation of the p160 coactivator glucocorticoid receptor-interacting protein1 View Abstract
PKC-mediated survival signaling in breast carcinoma cells: a role for MEK1-AP1 signaling. View Abstract
Mechanical and antibacterial bowel preparation in colon and rectal surgery. View Abstract
Regulation of estrogen-mediated cell survival and proliferation by p160 coactivators. View Abstract
Sensitization of apoptotically-resistant breast carcinoma cells to TNF and TRAIL by inhibition of p38 mitogen-activated protein kinase signaling. View Abstract
Solid and papillary epithelial neoplasm of the pancreas. View Abstract
Apoptosis, chemoresistance, and breast cancer: insights from the MCF-7 cell model system. View Abstract
Guidelines for withholding or termination of resuscitation in prehospital traumatic cardiopulmonary arrest. View Abstract
Guidelines for withholding or termination of resuscitation in prehospital cardiopulmonary arrest View Abstract
Sensitization of Apoptotically Resistant Breast Carcinoma Cells to TNF and TRAIL by Inhibition of P38 Mitogen-Activated Protein Kinase Signaling View Abstract
Therapy-induced leukemias and myelodysplastic syndromes after breast cancer treatment: an underemphasized clinical problem. View Abstract
Identification of mitogen-activated protein kinase kinase as a chemoresistant pathway in MCF-7 cells by using gene expression microarray. View Abstract
ATLS training: a novel approach. View Abstract
Identification of mitogen-activated protein kinase kinase 5 (mek5) as a chemoresistance pathway in MCF-7 cells using gene expression microarray View Abstract
Identification of mitogen-activated protein kinase kinase 5 (MEK5) as a chemoresistance pathway in MCF-7 cells using gene expression microarray View Abstract
Advanced Trauma Life Support Training: A novel approach View Abstract
Therapy-induced leukemias and myelodysplastic syndromes following breast cancer treatment View Abstract
Oestrogen-mediated suppression of tumour necrosis factor alpha-induced apoptosis in MCF-7 cells: subversion of Bcl-2 by anti-oestrogens. View Abstract
NF-kappa B-mediated chemoresistance in breast cancer cells. View Abstract
Gene microarray analysis reveals a novel hypoxia signal transduction pathway in human hepatocellular carcinoma cells. View Abstract
Esophageal carcinosarcoma. View Abstract
Oestrogen-mediated suppression of TNF-induced apoptosis in MCF-7 cells:subversion of Bcl-2 by antioestrogens View Abstract
NF-kappa â-mediated chemoresistance in breast cancer cells View Abstract
Pre-hospital DNR Protocol: An idea whose time has arrived View Abstract
Esophageal carcinosarcoma View Abstract
Identification and analysis of molecular mechanisms of chemoresistance in human breast carcinoma cells View Abstract
Identification of chemoresisstance targets in MCF-7 cells using gene microarray View Abstract
Differences in protein kinase C and estrogen receptor alpha, beta expression and signaling correlate with apoptotic sensitivity of MCF-7 breast cancer cell variants. View Abstract
PI3-K/AKT regulation of NF-kappaB signaling events in suppression of TNF-induced apoptosis. View Abstract
Cross-talk between phosphatidylinositol 3-kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions. View Abstract
Characterization of chemoresistance of MCF-7/ADR breast cancer cells View Abstract
Modulation of apoptotic pathways for therapeutic advantage in breast cancer View Abstract
MCF-7/ADR breast cancer cell chemonresistance View Abstract
Modulation of apoptotic pathways for therapeutic advantage: MCF-7 cells as a model system View Abstract
Phosphatidylinositol 3-kinase/Akt mediated regulation of NF-êB signaling events as a mechanism for suppression of TNF-induced apoptosis View Abstract
Differences in protein kinase C and estrogen receptor á, â expression and signaling correlate with apoptotic sensitivity of MCF-7 breast cancer cell variants View Abstract
Differences in susceptibility to tumor necrosis factor alpha-induced apoptosis among MCF-7 breast cancer cell variants. View Abstract
Phorbol ester and insulin-like growth factor-I suppression of TNF-á-induced apoptosis through a phosphatidylinositol-3-kinase mediated inhibition of ceramide formation and caspase activation View Abstract
MCF-7 breast cancer cell variants display differences in tumor necrosis factor á-included apoptosis View Abstract
Breast Leiomyoma View Abstract
Differences in susceptibility to tumor necrosis factor- á-induced apoptosis among MCF-7 breast cancer cell variants View Abstract
Cross-talk between phosphatidylinositol-3 kinase and sphingomyelinase pathways as a mechanism for cell survival/death decisions View Abstract
Differences in susceptibility to tumor necrosis factor á-induced apoptosis among MCF-7 breast cancer cell variants View Abstract
Overlapping and nonoverlapping cortical projections to cortex of the superior temporal sulcus in the rhesus monkey: double anterograde tracer studies. View Abstract
Parvalbumin staining delineates superior temporal polymodal cortex in Macaca mulatta View Abstract
Organization of cortical projections to the superior temporal polymodal cortex of the rhesus: double anterograde labeling studies View Abstract
Randomized clinical trial of fibrin sealant in patients undergoing resternotomy or reoperation after cardiac operations. A multicenter study. View Abstract
Preoperative three-dimensional reconstruction of the heart and great vessels in patients with congenital heart disease. Technique and initial results. View Abstract
Replacement of cardiac valves in children. View Abstract
Mexed-type total anomalous pulmonary venous drainage. Report of a successful surgical correction and review of the literature. View Abstract