Summary

This study will measure plasma concentrations of dexmedetomidine, fentanyl, morphine and midazolam in pediatric patients supported with extracorporeal membrane oxygenation (ECMO) aiming to understand the pharmacokinetics of these drugs in this setting.

Conditions

  • Drug Effect

Recruitment Status

RECRUITING

Eligibility Criteria

Inclusion Criteria:

* supported on ECMO
* receiving one or a combination of the following drugs dexmedetomidine, fentanyl, midazolam or morphine as part of sedation management

Exclusion Criteria:

-none

Gender

ALL

Min Age

0 Days

Max Age

17 Years

Download Date

2025-09-18

Principal Investigator

N/A

Primary Contact Information

Viviane Nasr, MD

617-355-6225

viviane.nasr@childrens.harvard.edu

Intervention

Intervention Type

DRUG

DRUG

DRUG

DRUG

Intervention Name

Dexmedetomidine

Fentanyl

Midazolam

Morphine

Contact

For more information and to contact the study team:

Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support NCT03593408 Viviane Nasr, MD 617-355-6225 viviane.nasr@childrens.harvard.edu