Summary

In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.

Conditions

  • Anesthesia
  • Intravenous Fluid
  • Blood Pressure

Recruitment Status

RECRUITING

Detailed Description

In this research study we want to learn more about using non-invasive tools as a way to predict whether or not a child under general anesthesia will require and respond to fluid administration. It is important for an anesthesiologist to know if a child would respond to fluid administration so that they can provide the optimal intervention for low blood pressure and avoid unnecessary treatment.

Eligibility Criteria

Inclusion Criteria:

* 0 to \< 18 years old
* Undergoing surgery at Boston Children's Hospital under general anesthesia
* mechanically ventilated with an endotracheal tube
* Monitored with an indwelling radial arterial catheter as part of the anesthetic plan for the scheduled surgical procedure

Exclusion Criteria:

* Prematurity
* Low birth weight
* Congenital heart disease
* Left or right ventricular dysfunction
* Cardiac arrhythmia
* Pulmonary hypertension
* Preoperative parenchymal or interstitial lung disease
* Intracranial hypertension
* Poor transthoracic acoustic window
* Obesity
* Allergy to ultrasound transmission gel
* Need for single lung ventilation
* Systemic hypertension on antihypertensive medications

Gender

ALL

Min Age

N/A

Max Age

17 Years

Download Date

2025-11-12

Principal Investigator

N/A

Primary Contact Information

Viviane Nasr, MD

617-355-6225

viviane.nasr@childrens.harvard.edu

Intervention

Intervention Type

OTHER

OTHER

Intervention Name

Lung Recruitment Maneuver

Fluid Administration

Contact

For more information and to contact the study team:

Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients NCT03431064 Viviane Nasr, MD 617-355-6225 viviane.nasr@childrens.harvard.edu