Cellular Imaging Core

alert iconFollowing guidelines from the Boston Children's Office of Research Administration and the Center for Disease Control, the Cellular Imaging Core will be closed until further notice due to the corona virus pandemic. The core can be an area of significant person-to-person contact, therefore, we are shutting down all microscopes in the CLS and Enders building starting Monday, March 16, 2020. We will be monitoring the situation and update you in the coming weeks of any changes to our plans and hope to reopen as soon as we are able. Please email the Assistant Director of the core at cvic.innocent@childrens.harvard.edu or the core manager at osama.alturkistani@childrens.harvard.edu if you have any questions.

Our mission

The Cellular Imaging Core (CIC) provides investigators with affordable access to state-of the-art microscopy and powerful image-analysis software. We offer free training and consultation services to achieve optimal images for individual research programs. Located mainly in CLS, the core continuously explores new technologies, and has invested heavily in new equipment and image analysis software. Lastly, we are committed to maintaining this core as a central resource for neuroscience research at Boston Children's Hospital and Harvard Medical School.

Our science and innovation 

Increasingly sophisticated methods to visualize tissue/cellular structure/neuronal circuits and to monitor real-time molecular interactions and biochemical reactions have contributed to recent progress both in developmental neurobiology and in studying neuro-developmental disorders. Current advancement has been augmented by access to specific antibodies for immunostaining, cloning of nucleic acids and in situ hybridization, new dyes and cell labeling techniques, in combination with a diverse array of powerful new microscopes.

Imaging technologies, such as stimulated emission depletion (STED) microscopy, laser scanning confocal microscopy, multiphoton excitation fluorescence, and WF epifluorescence are offered on site. Spinning Disk confocal microscopy and Array Tomography offer greatly increased resolution of cellular processes and require sophisticated analysis programs. Lastly, we uniquely offer scientific expertise in two photon imaging studies (consulting or projects).

We are supported by the NIH Mental Retardation Center Grant (U54 HD090255).

Learn more about the Cellular Imaging Core.