Research at Boston Children's Hospital
The research enterprise at Boston Children’s Hospital, comprising more than 3,000 researchers, is the world’s largest at a pediatric center. Our work is fueled by a deep understanding of disease biology coupled with world-class discovery platforms, including genetics and genomics, gene editing, bioinformatics, proteomics, bioengineering, image analysis, biobanks, disease-specific stem cell lines, and a range of animal models. We have special expertise in rare disease discovery, a robust Translational Research Program and large, diverse patient populations for clinical research and trials.
Warm congratulations to our researchers just named to the National Academy of Medicine:
Lois K. Lee, MD, MPH, for her foundational research on firearm injuries and leadership on pediatric firearm injury prevention.
Mustafa Sahin, MD, PhD, for his expertise in the neurobiology of autism and pioneering translational studies for neurogenetic disorders.
Timothy Springer, PhD, for his research on cell signal transmission and receptor-ligand interactions giving insight into immunology, hemostasis, and human disease.
Yi Zhang, PhD, for his fundamental contributions to the epigenetics field through identification and characterization of chromatin modifying enzymes.
They join 24 existing Boston Children’s members, bringing our total to 28 — truly an honor.
Making immunotherapy safe for AML
The Genovese Lab has developed an innovative strategy, using base editing techniques, that prevents immunotherapy from harming normal stem cells.
Nanobodies from alpacas could steer immune attacks on influenza
A new strategy takes advantage of alpacas’ unusually small antibodies, which guide flu drugs directly to infected cells while drawing a powerful immune attack.
Zika study reveals how infection can cause microcephaly
How did Zika in pregnant mothers cause their babies to be born with abnormally small heads? This study suggests possible targets to protect babies' developing brains.
Rising stars in research
Meet some of our scientists and the projects they hope to advance.