Steven Greenberg

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Research Overview

Dr. Steven Greenburg is a neurologist specializing in neuromuscular disorders and in informatics at the Boston Children’s Hospital Informatics Program.

His research areas include:

Understanding disease mechanisms for autoimmune muscle diseases
Developing therapies for certain autoimmune diseases
The manner in which scientific belief systems are supported by citations
Zinc induced copper deficiency

Publications

Vasomotion loss precedes impaired cerebrovascular reactivity and microbleeds in cerebral amyloid angiopathy. Brain Commun. 2025; 7(3):fcaf186. View Abstract
Amyloid-Related Imaging Abnormalities With Donanemab in Early Symptomatic Alzheimer Disease: Secondary Analysis of the TRAILBLAZER-ALZ and ALZ 2 Randomized Clinical Trials. JAMA Neurol. 2025 May 01; 82(5):461-469. View Abstract
Cross-sectional and longitudinal quantification of total white matter perivascular space volume fraction in Dutch-type Cerebral Amyloid Angiopathy. Neuroimage Clin. 2025 Apr 05; 46:103778. View Abstract
Donanemab: Appropriate use recommendations. J Prev Alzheimers Dis. 2025 May; 12(5):100150. View Abstract
Volume Tolerance and Prognostic Impact of Hematoma Expansion in Deep and Lobar Intracerebral Hemorrhage. Stroke. 2025 May; 56(5):1224-1231. View Abstract
Cerebrospinal Fluid Beta-Amyloid Concentration and Clinical and Radiographic Manifestations of Cerebral Amyloid Angiopathy. J Am Heart Assoc. 2025 Mar 04; 14(5):e040025. View Abstract
Left atrial appendage closure for patients with atrial fibrillation at high intracranial haemorrhagic risk. Stroke Vasc Neurol. 2025 Feb 25; 10(1):86-94. View Abstract
Left atrial appendage closure in patients with atrial fibrillation and acute ischaemic stroke despite anticoagulation. Stroke Vasc Neurol. 2025 Feb 25; 10(1):120-128. View Abstract
Characterizing the underlying microangiopathy of deep cerebellar intracerebral hemorrhage. J Neurol. 2025 Jan 24; 272(2):167. View Abstract
Amyloid-related imaging abnormalities: manifestations, metrics and mechanisms. Nat Rev Neurol. 2025 Apr; 21(4):193-203. View Abstract
Genetics of intracerebral hemorrhage. J Cereb Blood Flow Metab. 2025 Jan 07; 271678X241310401. View Abstract
MRI free water mediates the association between diffusion tensor image analysis along the perivascular space and executive function in four independent middle to aged cohorts. Alzheimers Dement. 2025 Feb; 21(2):e14453. View Abstract
White matter free water mediates the associations between placental growth factor, white matter hyperintensities, and cognitive status. Alzheimers Dement. 2025 Feb; 21(2):e14408. View Abstract
Vascular Neurology Considerations for Antiamyloid Immunotherapy: A Science Advisory From the American Heart Association. Stroke. 2025 Jan; 56(1):e30-e38. View Abstract
Biological validation of peak-width of skeletonized mean diffusivity as a VCID biomarker: The MarkVCID Consortium. Alzheimers Dement. 2024 Dec; 20(12):8814-8824. View Abstract
Neuropathological Correlates of White Matter Hyperintensities in Cerebral Amyloid Angiopathy. J Am Heart Assoc. 2024 Nov 19; 13(22):e035744. View Abstract
No replicating evidence for anti-amyloid-ß autoantibodies in cerebral amyloid angiopathy-related inflammation. Ann Clin Transl Neurol. 2024 Oct; 11(10):2563-2571. View Abstract
Cerebral Amyloid Angiopathy and Nontraumatic Subdural Hemorrhage. JAMA Neurol. 2024 Aug 01; 81(8):888. View Abstract
Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function. Aging Dis. 2024 Aug 01; 15(4):1885-1898. View Abstract
Parental Influence on Intracerebral Hemorrhage Onset in Hereditary Dutch-Type Cerebral Amyloid Angiopathy. Cerebrovasc Dis. 2024 Jul 17; 1-6. View Abstract
Cerebrovascular reactivity MRI as a biomarker for cerebral small vessel disease-related cognitive decline: Multi-site validation in the MarkVCID Consortium. Alzheimers Dement. 2024 08; 20(8):5281-5289. View Abstract
Enlarged perivascular spaces in the basal ganglia are associated with arteries not veins. J Cereb Blood Flow Metab. 2024 Nov; 44(11):1362-1377. View Abstract
Is CAA a perivascular brain clearance disease? A discussion of the evidence to date and outlook for future studies. Cell Mol Life Sci. 2024 May 27; 81(1):239. View Abstract
Sex differences in histopathological markers of cerebral amyloid angiopathy and related hemorrhage. Int J Stroke. 2024 Oct; 19(8):947-956. View Abstract
Hypertension control after intracerebral hemorrhage among varying small vessel disease etiologies. Neurol Sci. 2024 Oct; 45(10):4913-4921. View Abstract
Loss of spontaneous vasomotion precedes impaired cerebrovascular reactivity and microbleeds in a mouse model of cerebral amyloid angiopathy. bioRxiv. 2024 Apr 30. View Abstract
ARIA Insights from the Donanemab Trials (P1-9.001). Neurology. 2024 Apr 09; 102(7_supplement_1):3339. View Abstract
Rationale and Design of the Statin Use in Intracerebral Hemorrhage Patients (SATURN) Trial. Cerebrovasc Dis. 2025; 54(2):270-277. View Abstract
Temporal Ordering of Biomarkers in Dutch-Type Hereditary Cerebral Amyloid Angiopathy. Stroke. 2024 Apr; 55(4):954-962. View Abstract
Association of Long-Term Blood Pressure Variability with Cerebral Amyloid Angiopathy-related Brain Injury and Cognitive Decline. medRxiv. 2024 Feb 27. View Abstract
Minocycline in Severe Cerebral Amyloid Angiopathy: A Single-Center Cohort Study. J Am Heart Assoc. 2024 Feb 20; 13(4):e033464. View Abstract
Editorial: Cerebral amyloid angiopathy: from bench to bedside. Front Neurosci. 2024; 18:1370352. View Abstract
Fluid biomarkers in cerebral amyloid angiopathy. Front Neurosci. 2024; 18:1347320. View Abstract
Cerebral Amyloid Angiopathy. Stroke. 2024 May; 55(5):1409-1411. View Abstract
Greater White Matter Hyperintensity Volume Is Associated with the Number of Microhemorrhages in Preclinical Alzheimer's Disease. J Prev Alzheimers Dis. 2024; 11(4):869-873. View Abstract
Association Between Hippocampal Volumes and Cognition in Cerebral Amyloid Angiopathy. Neurology. 2024 Jan 23; 102(2):e207854. View Abstract
Sensitivity and Specificity of the Boston Criteria Version 2.0 for the Diagnosis of Cerebral Amyloid Angiopathy in a Community-Based Sample. Neurology. 2024 Jan 09; 102(1):e207940. View Abstract
SWI versus GRE-T2*: Assessing cortical superficial siderosis in advanced cerebral amyloid angiopathy. Rev Neurol (Paris). 2024 Jun; 180(6):532-538. View Abstract
Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease. JAMA Neurol. 2023 12 01; 80(12):1353-1363. View Abstract
Antiplatelet Agent Use After Stroke due to Intracerebral Hemorrhage. Stroke. 2023 12; 54(12):3173-3181. View Abstract
Blood Transfusion and Brain Amyloidosis: Should We Be Worried? JAMA. 2023 09 12; 330(10):921-922. View Abstract
Histopathological Correlates of Lobar Microbleeds in False-Positive Cerebral Amyloid Angiopathy Cases. Ann Neurol. 2023 11; 94(5):856-870. View Abstract
Cortical superficial siderosis is associated with reactive astrogliosis in cerebral amyloid angiopathy. J Neuroinflammation. 2023 Aug 27; 20(1):195. View Abstract
Association Between Hematoma Expansion Severity and Outcome and Its Interaction With Baseline Intracerebral Hemorrhage Volume. Neurology. 2023 10 17; 101(16):e1606-e1613. View Abstract
Left ventricular hypertrophy and left atrial size are associated with ischemic strokes among non-vitamin K antagonist oral anticoagulant users. J Neurol. 2023 Nov; 270(11):5578-5588. View Abstract
Correction: Decreased Cerebrospinal Fluid Amyloid ß 38, 40, 42, and 43 Levels in Sporadic and Hereditary Cerebral Amyloid Angiopathy. Ann Neurol. 2023 Jul; 94(1):208-209. View Abstract
Mechanistic Implications of Cortical Superficial Siderosis in Patients With Mixed Location Intracerebral Hemorrhage and Cerebral Microbleeds. Neurology. 2023 08 08; 101(6):e636-e644. View Abstract
Boston criteria version 2.0 and non-haemorrhagic presentations - Authors' reply. Lancet Neurol. 2023 06; 22(6):466-467. View Abstract
Neuronally Derived Soluble Abeta Evokes Cell-Wide Astrocytic Calcium Dysregulation in Absence of Amyloid Plaques in Vivo. J Neurosci. 2023 06 28; 43(26):4926-4940. View Abstract
Progression of cerebral amyloid angiopathy: a pathophysiological framework. Lancet Neurol. 2023 07; 22(7):632-642. View Abstract
Neuroimaging standards for research into small vessel disease-advances since 2013. Lancet Neurol. 2023 07; 22(7):602-618. View Abstract
Seed to Bleed: Iatrogenic Cerebral Amyloid Angiopathy. Stroke. 2023 05; 54(5):1224-1226. View Abstract
Peak width of skeletonized mean diffusivity and cognitive performance in cerebral amyloid angiopathy. Front Neurosci. 2023; 17:1141007. View Abstract
Impact of region of interest definition on visual stimulation-based cerebral vascular reactivity functional MRI with a special focus on applications in cerebral amyloid angiopathy. NMR Biomed. 2023 07; 36(7):e4916. View Abstract
Apathy in Patients With Cerebral Amyloid Angiopathy: A Multimodal Neuroimaging Study. Neurology. 2023 05 09; 100(19):e2007-e2016. View Abstract
Placental growth factor as a sensitive biomarker for vascular cognitive impairment. Alzheimers Dement. 2023 08; 19(8):3519-3527. View Abstract
Decreased Cerebrospinal Fluid Amyloid ß 38, 40, 42, and 43 Levels in Sporadic and Hereditary Cerebral Amyloid Angiopathy. Ann Neurol. 2023 06; 93(6):1173-1186. View Abstract
Decreased ratios of matrix metalloproteinases to tissue-type inhibitors in cerebrospinal fluid in sporadic and hereditary cerebral amyloid angiopathy. Alzheimers Res Ther. 2023 01 30; 15(1):26. View Abstract
Peak Width of Skeletonized Mean Diffusivity: A Neuroimaging Marker for White Matter Injury. Radiology. 2023 03; 306(3):e212780. View Abstract
Sex Differences in Onset and Progression of Cerebral Amyloid Angiopathy. Stroke. 2023 02; 54(2):306-314. View Abstract
The impending era of beta-amyloid therapy: Clinical and research considerations for treating vascular contributions to neurodegeneration. Cereb Circ Cogn Behav. 2024; 6:100159. View Abstract
Spontaneous vasomotion propagates along pial arterioles in the awake mouse brain like stimulus-evoked vascular reactivity. J Cereb Blood Flow Metab. 2023 10; 43(10):1752-1763. View Abstract
Using Noncontrast Computed Tomography to Improve Prediction of Intracerebral Hemorrhage Expansion. Stroke. 2023 02; 54(2):567-574. View Abstract
Lecanemab: Appropriate Use Recommendations. J Prev Alzheimers Dis. 2023; 10(3):362-377. View Abstract
Association of MRI Visible Perivascular Spaces and Neurofilament Light Chain: The Framingham Heart Study. J Alzheimers Dis. 2023; 95(3):1133-1145. View Abstract
Multi-Site Cross-Site Inter-Rater and Test-Retest Reliability and Construct Validity of the MarkVCID White Matter Hyperintensity Growth and Regression Protocol. J Alzheimers Dis. 2023; 96(2):683-693. View Abstract
MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium. Alzheimers Dement (Amst). 2022; 14(1):e12362. View Abstract
Association of Depression Onset and Treatment With Blood Pressure Control After Intracerebral Hemorrhage. Stroke. 2023 01; 54(1):105-112. View Abstract
A Causal Classification System for Intracerebral Hemorrhage Subtypes. Ann Neurol. 2023 01; 93(1):16-28. View Abstract
Peak width of skeletonized mean diffusivity in cerebral amyloid angiopathy: Spatial signature, cognitive, and neuroimaging associations. Front Neurosci. 2022; 16:1051038. View Abstract
Blood Pressure Control Targets and Risk of Cardiovascular and Cerebrovascular Events After Intracerebral Hemorrhage. Stroke. 2023 01; 54(1):78-86. View Abstract
Blood-brain barrier leakage and perivascular inflammation in cerebral amyloid angiopathy. Brain Commun. 2022; 4(5):fcac245. View Abstract
External ventricular drain placement is associated with lower mortality after intracerebral hemorrhage with intraventricular hemorrhage. Int J Emerg Med. 2022 Sep 15; 15(1):51. View Abstract
Clinical and neuroimaging risk factors associated with the development of intracerebral hemorrhage while taking direct oral anticoagulants. J Neurol. 2022 Dec; 269(12):6589-6596. View Abstract
Improving detection of cerebral small vessel disease aetiology in patients with isolated lobar intracerebral haemorrhage. Stroke Vasc Neurol. 2023 Feb; 8(1):26-33. View Abstract
Forkhead box O3 longevity genotype may attenuate the impact of hypertension on risk of intracerebral haemorrhage. J Hypertens. 2022 11 01; 40(11):2230-2235. View Abstract
The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study. Lancet Neurol. 2022 08; 21(8):714-725. View Abstract
Effects of cerebral amyloid angiopathy on the brain vasculome. Aging Cell. 2022 08; 21(8):e13503. View Abstract
Progressive White Matter Injury in Preclinical Dutch Cerebral Amyloid Angiopathy. Ann Neurol. 2022 09; 92(3):358-363. View Abstract
Association of Symptomatic Hearing Loss with Functional and Cognitive Recovery 1 Year after Intracerebral Hemorrhage. J Stroke. 2022 May; 24(2):303-306. View Abstract
2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2022 07; 53(7):e282-e361. View Abstract
Cerebellar atrophy and its implications on gait in cerebral amyloid angiopathy. J Neurol Neurosurg Psychiatry. 2022 May 09. View Abstract
Lobar intracerebral hemorrhage and risk of subsequent uncontrolled blood pressure. Eur Stroke J. 2022 Sep; 7(3):280-288. View Abstract
Corpus callosum lesions are associated with worse cognitive performance in cerebral amyloid angiopathy. Brain Commun. 2022; 4(3):fcac105. View Abstract
Histopathology of Cerebral Microinfarcts and Microbleeds in Spontaneous Intracerebral Hemorrhage. Transl Stroke Res. 2023 04; 14(2):174-184. View Abstract
Longitudinal Progression of Magnetic Resonance Imaging Markers and Cognition in Dutch-Type Hereditary Cerebral Amyloid Angiopathy. Stroke. 2022 06; 53(6):2006-2015. View Abstract
Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits. Alzheimers Dement (Amst). 2022; 14(1):e12261. View Abstract
Endovascular Treatment and Thrombolysis for Acute Ischemic Stroke in Patients With Premorbid Disability or Dementia: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke. 2022 05; 53(5):e204-e217. View Abstract
CT Diagnosis of Cerebral Amyloid Angiopathy: Blood Will Out. Neurology. 2022 05 17; 98(20):823-824. View Abstract
Elevated expression of urokinase plasminogen activator in rodent models and patients with cerebral amyloid angiopathy. Neuropathol Appl Neurobiol. 2022 08; 48(5):e12804. View Abstract
Long-Term Blood Pressure Variability and Major Adverse Cardiovascular and Cerebrovascular Events After Intracerebral Hemorrhage. J Am Heart Assoc. 2022 03 15; 11(6):e024158. View Abstract
What does aducanumab treatment of Alzheimer's disease mean for research on vascular cognitive disorders? Cereb Circ Cogn Behav. 2022; 3:100044. View Abstract
Biological and Social Determinants of Hypertension Severity Before vs After Intracerebral Hemorrhage. Neurology. 2022 03 29; 98(13):e1349-e1360. View Abstract
Maximizing Brain Health After Hemorrhagic Stroke: Bugher Foundation Centers of Excellence. Stroke. 2022 03; 53(3):1020-1029. View Abstract
Histopathological correlates of haemorrhagic lesions on ex vivo magnetic resonance imaging in immunized Alzheimer's disease cases. Brain Commun. 2022; 4(1):fcac021. View Abstract
Effect of vascular amyloid on white matter disease is mediated by vascular dysfunction in cerebral amyloid angiopathy. J Cereb Blood Flow Metab. 2022 07; 42(7):1272-1281. View Abstract
Vascular Contributions to Brain Health: Cross-Cutting Themes. Stroke. 2022 02; 53(2):391-393. View Abstract
Imaging markers of intracerebral hemorrhage expansion in patients with unclear symptom onset. Int J Stroke. 2022 Oct; 17(9):1013-1020. View Abstract
Brain Deep Medullary Veins on 7T MRI in Dutch-Type Hereditary Cerebral Amyloid Angiopathy. J Alzheimers Dis. 2022; 90(1):381-388. View Abstract
Perivascular space dilation is associated with vascular amyloid-ß accumulation in the overlying cortex. Acta Neuropathol. 2022 03; 143(3):331-348. View Abstract
Latent profile analysis of cognitive decline and depressive symptoms after intracerebral hemorrhage. BMC Neurol. 2021 Dec 10; 21(1):481. View Abstract
Normal cerebrospinal fluid concentrations of PDGFRß in patients with cerebral amyloid angiopathy and Alzheimer's disease. Alzheimers Dement. 2022 10; 18(10):1788-1796. View Abstract
Correction to: Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer's disease, but not in cerebral amyloid angiopathy. Alzheimers Res Ther. 2021 Nov 16; 13(1):189. View Abstract
Cerebral Small Vessel Disease and Depression Among Intracerebral Hemorrhage Survivors. Stroke. 2022 02; 53(2):523-531. View Abstract
Cerebrospinal fluid levels of the neurotrophic factor neuroleukin are increased in early Alzheimer's disease, but not in cerebral amyloid angiopathy. Alzheimers Res Ther. 2021 09 24; 13(1):160. View Abstract
Cerebellar hemorrhages in patients with Dutch-type hereditary cerebral amyloid angiopathy. Int J Stroke. 2022 07; 17(6):637-644. View Abstract
Idiopathic primary intraventricular hemorrhage and cerebral small vessel disease. Int J Stroke. 2022 07; 17(6):645-653. View Abstract
Deep learning assisted quantitative assessment of histopathological markers of Alzheimer's disease and cerebral amyloid angiopathy. Acta Neuropathol Commun. 2021 08 21; 9(1):141. View Abstract
Intensive Blood Pressure Lowering and DWI Lesions in Intracerebral Hemorrhage: Exploratory Analysis of the ATACH-2 Randomized Trial. Neurocrit Care. 2022 02; 36(1):71-81. View Abstract
Rare Missense Functional Variants at COL4A1 and COL4A2 in Sporadic Intracerebral Hemorrhage. Neurology. 2021 Jul 19; 97(3):e236-e247. View Abstract
Risk of intracranial haemorrhage and ischaemic stroke after convexity subarachnoid haemorrhage in cerebral amyloid angiopathy: international individual patient data pooled analysis. J Neurol. 2022 Mar; 269(3):1427-1438. View Abstract
Off-label use of aducanumab for cerebral amyloid angiopathy. Lancet Neurol. 2021 08; 20(8):596-597. View Abstract
Computed Tomography Angiography Spot Sign, Hematoma Expansion, and Functional Outcome in Spontaneous Cerebellar Intracerebral Hemorrhage. Stroke. 2021 08; 52(9):2902-2909. View Abstract
Decreased Basal Ganglia Volume in Cerebral Amyloid Angiopathy. J Stroke. 2021 May; 23(2):223-233. View Abstract
Cognitive Impairment and Dementia After Stroke: Design and Rationale for the DISCOVERY Study. Stroke. 2021 08; 52(8):e499-e516. View Abstract
Cerebral Amyloid Angiopathy-Related Transient Focal Neurologic Episodes. Neurology. 2021 08 03; 97(5):231-238. View Abstract
Impact of Uncontrolled Hypertension at 3 Months After Intracerebral Hemorrhage. J Am Heart Assoc. 2021 06; 10(11):e020392. View Abstract
Contribution of Racial and Ethnic Differences in Cerebral Small Vessel Disease Subtype and Burden to Risk of Cerebral Hemorrhage Recurrence. Neurology. 2021 05 18; 96(20):e2469-e2480. View Abstract
Erratum. Alzheimers Dement. 2021 May; 17(5):906-907. View Abstract
Occipital Cortical Calcifications in Cerebral Amyloid Angiopathy. Stroke. 2021 05; 52(5):1851-1855. View Abstract
Hematoma Expansion in Intracerebral Hemorrhage With Unclear Onset. Neurology. 2021 05 11; 96(19):e2363-e2371. View Abstract
Cerebral microbleeds and prediction of intracranial haemorrhage. Lancet Neurol. 2021 04; 20(4):252-254. View Abstract
Plasma Amyloid-Beta Levels in a Pre-Symptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross-Sectional and Longitudinal Investigation. Int J Mol Sci. 2021 Mar 13; 22(6). View Abstract
Peak Width of Skeletonized Mean Diffusivity as Neuroimaging Biomarker in Cerebral Amyloid Angiopathy. AJNR Am J Neuroradiol. 2021 05; 42(5):875-881. View Abstract
Association of Memory Impairment With Concomitant Tau Pathology in Patients With Cerebral Amyloid Angiopathy. Neurology. 2021 04 13; 96(15):e1975-e1986. View Abstract
A Roadmap for Developing Plasma Diagnostic and Prognostic Biomarkers of Cerebral Cavernous Angioma With Symptomatic Hemorrhage (CASH). Neurosurgery. 2021 02 16; 88(3):686-697. View Abstract
Lacunes, Microinfarcts, and Vascular Dysfunction in Cerebral Amyloid Angiopathy. Neurology. 2021 03 23; 96(12):e1646-e1654. View Abstract
MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols. Alzheimers Dement. 2021 04; 17(4):716-725. View Abstract
MarkVCID cerebral small vessel consortium: I. Enrollment, clinical, fluid protocols. Alzheimers Dement. 2021 04; 17(4):704-715. View Abstract
Lack of racial and ethnic-based differences in acute care delivery in intracerebral hemorrhage. Int J Emerg Med. 2021 Jan 19; 14(1):6. View Abstract
Presymptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy-Related Blood Metabolite Alterations. J Alzheimers Dis. 2021; 79(2):895-903. View Abstract
Cerebral amyloid angiopathy is associated with decreased functional brain connectivity. Neuroimage Clin. 2021; 29:102546. View Abstract
Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy. Brain. 2020 12 05; 143(11):3343-3351. View Abstract
CT-Visible Convexity Subarachnoid Hemorrhage is Associated With Cortical Superficial Siderosis and Predicts Recurrent ICH. Neurology. 2021 02 16; 96(7):e986-e994. View Abstract
Association of Cerebral Small Vessel Disease and Cognitive Decline After Intracerebral Hemorrhage. Neurology. 2021 01 12; 96(2):e182-e192. View Abstract
Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop. Alzheimers Dement. 2020 12; 16(12):1714-1733. View Abstract
Association Between Immunosuppressive Treatment and Outcomes of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2020 10 01; 77(10):1261-1269. View Abstract
Association of Selective Serotonin Reuptake Inhibitor Use After Intracerebral Hemorrhage With Hemorrhage Recurrence and Depression Severity. JAMA Neurol. 2020 Aug 31. View Abstract
Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future. Alzheimers Dement. 2020 11; 16(11):1571-1581. View Abstract
Clearance of interstitial fluid (ISF) and CSF (CLIC) group-part of Vascular Professional Interest Area (PIA): Cerebrovascular disease and the failure of elimination of Amyloid-ß from the brain and retina with age and Alzheimer's disease-Opportunities for Therapy. Alzheimers Dement (Amst). 2020; 12(1):e12053. View Abstract
White matter atrophy in cerebral amyloid angiopathy. Neurology. 2020 08 04; 95(5):e554-e562. View Abstract
Combining Imaging and Genetics to Predict Recurrence of Anticoagulation-Associated Intracerebral Hemorrhage. Stroke. 2020 07; 51(7):2153-2160. View Abstract
Seven-Year Experience From the National Institute of Neurological Disorders and Stroke-Supported Network for Excellence in Neuroscience Clinical Trials. JAMA Neurol. 2020 06 01; 77(6):755-763. View Abstract
Cortical superficial siderosis progression in cerebral amyloid angiopathy: Prospective MRI study. Neurology. 2020 04 28; 94(17):e1853-e1865. View Abstract
Hereditary cerebral amyloid angiopathy, Piedmont-type mutation. Neurol Genet. 2020 Apr; 6(2):e411. View Abstract
Histopathology of diffusion-weighted imaging-positive lesions in cerebral amyloid angiopathy. Acta Neuropathol. 2020 05; 139(5):799-812. View Abstract
Convexity subarachnoid hemorrhage in lobar intracerebral hemorrhage: A prognostic marker. Neurology. 2020 03 03; 94(9):e968-e977. View Abstract
Apolipoprotein D: a potential biomarker for cerebral amyloid angiopathy. Neuropathol Appl Neurobiol. 2020 08; 46(5):431-440. View Abstract
White Matter Hyperintensities and Blood Pressure Lowering in Acute Intracerebral Hemorrhage: A Secondary Analysis of the ATACH-2 Trial. Neurocrit Care. 2020 02; 32(1):180-186. View Abstract
In vivo characterization of spontaneous microhemorrhage formation in mice with cerebral amyloid angiopathy. J Cereb Blood Flow Metab. 2021 01; 41(1):82-91. View Abstract
Cerebral Small Vessel Diseases and Sleep Related Strokes. J Stroke Cerebrovasc Dis. 2020 Apr; 29(4):104606. View Abstract
Cerebral amyloid angiopathy and Alzheimer disease - one peptide, two pathways. Nat Rev Neurol. 2020 01; 16(1):30-42. View Abstract
Vasomotion as a Driving Force for Paravascular Clearance in the Awake Mouse Brain. Neuron. 2020 02 05; 105(3):549-561.e5. View Abstract
Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative. J Cereb Blood Flow Metab. 2020 02; 40(2):231-245. View Abstract
Vascular contributions to cognitive impairment and dementia: Research consortia that focus on etiology and treatable targets to lessen the burden of dementia worldwide. Alzheimers Dement (N Y). 2019; 5:789-796. View Abstract
Cortical superficial siderosis and bleeding risk in cerebral amyloid angiopathy: A meta-analysis. Neurology. 2019 12 10; 93(24):e2192-e2202. View Abstract
Genome-wide association study of cerebral small vessel disease reveals established and novel loci. Brain. 2019 10 01; 142(10):3176-3189. View Abstract
APOE genotype, hypertension severity and outcomes after intracerebral haemorrhage. Brain Commun. 2019; 1(1):fcz018. View Abstract
Advancing diagnostic criteria for sporadic cerebral amyloid angiopathy: Study protocol for a multicenter MRI-pathology validation of Boston criteria v2.0. Int J Stroke. 2019 12; 14(9):956-971. View Abstract
Standards for Detecting, Interpreting, and Reporting Noncontrast Computed Tomographic Markers of Intracerebral Hemorrhage Expansion. Ann Neurol. 2019 10; 86(4):480-492. View Abstract
Amyloid imaging of dutch-type hereditary cerebral amyloid angiopathy carriers. Ann Neurol. 2019 10; 86(4):616-625. View Abstract
New and expanding ventricular hemorrhage predicts poor outcome in acute intracerebral hemorrhage. Neurology. 2019 08 27; 93(9):e879-e888. View Abstract
APOE and cortical superficial siderosis in CAA: Meta-analysis and potential mechanisms. Neurology. 2019 07 23; 93(4):e358-e371. View Abstract
Different microvascular alterations underlie microbleeds and microinfarcts. Ann Neurol. 2019 08; 86(2):279-292. View Abstract
Cerebellar Microbleed Distribution Patterns and Cerebral Amyloid Angiopathy. Stroke. 2019 07; 50(7):1727-1733. View Abstract
Consensus Recommendations for the Conduct, Training, Implementation, and Research of Perioperative Handoffs. Anesth Analg. 2019 05; 128(5):e71-e78. View Abstract
Secondary Bleeding During Acute Experimental Intracerebral Hemorrhage. Stroke. 2019 05; 50(5):1210-1215. View Abstract
Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis. JAMA Neurol. 2019 04 01; 76(4):480-491. View Abstract
Cortical Superficial Siderosis Evolution. Stroke. 2019 04; 50(4):954-962. View Abstract
Spatial Signature of White Matter Hyperintensities in Stroke Patients. Front Neurol. 2019; 10:208. View Abstract
Immunotherapy with ponezumab for probable cerebral amyloid angiopathy. Ann Clin Transl Neurol. 2019 Apr; 6(4):795-806. View Abstract
Deferoxamine mesylate in patients with intracerebral haemorrhage (i-DEF): a multicentre, randomised, placebo-controlled, double-blind phase 2 trial. Lancet Neurol. 2019 05; 18(5):428-438. View Abstract
Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration. Alzheimers Dement (Amst). 2019 Dec; 11:191-204. View Abstract
Cortical superficial siderosis and recurrent intracerebral hemorrhage risk in cerebral amyloid angiopathy: Large prospective cohort and preliminary meta-analysis. Int J Stroke. 2019 10; 14(7):723-733. View Abstract
Multiple Approaches to Diffusion Magnetic Resonance Imaging in Hereditary Cerebral Amyloid Angiopathy Mutation Carriers. J Am Heart Assoc. 2019 02 05; 8(3):e011288. View Abstract
Blood-Brain Barrier Leakage and Microvascular Lesions in Cerebral Amyloid Angiopathy. Stroke. 2019 02; 50(2):328-335. View Abstract
Histopathology of diffusion imaging abnormalities in cerebral amyloid angiopathy. Neurology. 2019 02 26; 92(9):e933-e943. View Abstract
Implications of cortical superficial siderosis in CAA: Superficial relationships. Neurology. 2019 02 19; 92(8):360-361. View Abstract
Cerebral small vessel disease in patients with spontaneous cerebellar hemorrhage. J Neurol. 2019 Mar; 266(3):625-630. View Abstract
Predictors for Late Post-Intracerebral Hemorrhage Dementia in Patients with Probable Cerebral Amyloid Angiopathy. J Alzheimers Dis. 2019; 71(2):435-442. View Abstract
Cardioembolic Stroke Risk and Recovery After Anticoagulation-Related Intracerebral Hemorrhage. Stroke. 2018 11; 49(11):2652-2658. View Abstract
Cerebral Cortical Microinfarcts on Magnetic Resonance Imaging and Their Association With Cognition in Cerebral Amyloid Angiopathy. Stroke. 2018 10; 49(10):2330-2336. View Abstract
Integration of Computed Tomographic Angiography Spot Sign and Noncontrast Computed Tomographic Hypodensities to Predict Hematoma Expansion. Stroke. 2018 09; 49(9):2067-2073. View Abstract
Cerebral Amyloid Angiopathy With Vascular Iron Accumulation and Calcification. Stroke. 2018 09; 49(9):2081-2087. View Abstract
Perivascular Spaces Volume in Sporadic and Hereditary (Dutch-Type) Cerebral Amyloid Angiopathy. Stroke. 2018 08; 49(8):1913-1919. View Abstract
Cerebral Microbleeds and the Effect of Intensive Blood Pressure Reduction on Hematoma Expansion and Functional Outcomes: A Secondary Analysis of the ATACH-2 Randomized Clinical Trial. JAMA Neurol. 2018 07 01; 75(7):850-859. View Abstract
17p12 Influences Hematoma Volume and Outcome in Spontaneous Intracerebral Hemorrhage. Stroke. 2018 07; 49(7):1618-1625. View Abstract
Hypertension and intracerebral hemorrhage recurrence among white, black, and Hispanic individuals. Neurology. 2018 07 03; 91(1):e37-e44. View Abstract
Innovative Magnetic Resonance Imaging Markers of Hereditary Cerebral Amyloid Angiopathy at 7 Tesla. Stroke. 2018 06; 49(6):1518-1520. View Abstract
Advances in Stroke 2017. Stroke. 2018 05; 49(5):e174-e199. View Abstract
Predicting Intracerebral Hemorrhage Expansion With Noncontrast Computed Tomography: The BAT Score. Stroke. 2018 05; 49(5):1163-1169. View Abstract
Incidence and Etiology of Microinfarcts in Patients with Ischemic Stroke. J Neuroimaging. 2018 07; 28(4):406-411. View Abstract
The growing clinical spectrum of cerebral amyloid angiopathy. Curr Opin Neurol. 2018 Feb; 31(1):28-35. View Abstract
Men Experience Higher Risk of Pneumonia and Death After Intracerebral Hemorrhage. Neurocrit Care. 2018 02; 28(1):77-82. View Abstract
Core cerebrospinal fluid biomarker profile in cerebral amyloid angiopathy: A meta-analysis. Neurology. 2018 02 27; 90(9):e754-e762. View Abstract
Impaired memory is more closely associated with brain beta-amyloid than leukoaraiosis in hypertensive patients with cognitive symptoms. PLoS One. 2018; 13(1):e0191345. View Abstract
Clinical significance of cerebral microbleeds on MRI: A comprehensive meta-analysis of risk of intracerebral hemorrhage, ischemic stroke, mortality, and dementia in cohort studies (v1). Int J Stroke. 2018 07; 13(5):454-468. View Abstract
Diagnosis of Cerebral Amyloid Angiopathy: Evolution of the Boston Criteria. Stroke. 2018 02; 49(2):491-497. View Abstract
Mixed-location cerebral hemorrhage/microbleeds: Underlying microangiopathy and recurrence risk. Neurology. 2018 01 09; 90(2):e119-e126. View Abstract
Cerebellar Hematoma Location: Implications for the Underlying Microangiopathy. Stroke. 2018 01; 49(1):207-210. View Abstract
Blood pressure from mid- to late life and risk of incident dementia. Neurology. 2017 Dec 12; 89(24):2447-2454. View Abstract
Alzheimer's Disease-Related Dementias Summit 2016: National research priorities. Neurology. 2017 Dec 05; 89(23):2381-2391. View Abstract
Oral Anticoagulation and Functional Outcome after Intracerebral Hemorrhage. Ann Neurol. 2017 Nov; 82(5):755-765. View Abstract
Cortical superficial siderosis multifocality in cerebral amyloid angiopathy: A prospective study. Neurology. 2017 Nov 21; 89(21):2128-2135. View Abstract
Evolution of DWI lesions in cerebral amyloid angiopathy: Evidence for ischemia. Neurology. 2017 Nov 21; 89(21):2136-2142. View Abstract
Acute convexity subarachnoid haemorrhage and cortical superficial siderosis in probable cerebral amyloid angiopathy without lobar haemorrhage. J Neurol Neurosurg Psychiatry. 2018 04; 89(4):397-403. View Abstract
Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke. Brain. 2017 Oct 01; 140(10):2663-2672. View Abstract
Revisiting Grade 3 Diffuse Axonal Injury: Not All Brainstem Microbleeds are Prognostically Equal. Neurocrit Care. 2017 Oct; 27(2):199-207. View Abstract
Total small vessel disease burden and brain network efficiency in cerebral amyloid angiopathy. J Neurol Sci. 2017 Nov 15; 382:10-12. View Abstract
The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice. J Neurol Neurosurg Psychiatry. 2017 11; 88(11):982-994. View Abstract
Intensive Blood Pressure Reduction and Spot Sign in Intracerebral Hemorrhage: A Secondary Analysis of a Randomized Clinical Trial. JAMA Neurol. 2017 08 01; 74(8):950-960. View Abstract
Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds: A meta-analysis. Neurology. 2017 Aug 22; 89(8):820-829. View Abstract
Phantom-based standardization of CT angiography images for spot sign detection. Neuroradiology. 2017 Sep; 59(9):839-844. View Abstract
Detection, risk factors, and functional consequences of cerebral microinfarcts. Lancet Neurol. 2017 09; 16(9):730-740. View Abstract
Blood pressure reduction and noncontrast CT markers of intracerebral hemorrhage expansion. Neurology. 2017 Aug 08; 89(6):548-554. View Abstract
William M. Feinberg Award for Excellence in Clinical Stroke: Big Pictures and Small Vessels. Stroke. 2017 09; 48(9):2628-2631. View Abstract
Hemorrhage recurrence risk factors in cerebral amyloid angiopathy: Comparative analysis of the overall small vessel disease severity score versus individual neuroimaging markers. J Neurol Sci. 2017 Sep 15; 380:64-67. View Abstract
Emerging concepts in sporadic cerebral amyloid angiopathy. Brain. 2017 Jul 01; 140(7):1829-1850. View Abstract
Timing of INR reversal using fresh-frozen plasma in warfarin-associated intracerebral hemorrhage. Intern Emerg Med. 2018 06; 13(4):557-565. View Abstract
Sex differences in intracerebral hemorrhage expansion and mortality. J Neurol Sci. 2017 Aug 15; 379:112-116. View Abstract
Distribution of lacunes in cerebral amyloid angiopathy and hypertensive small vessel disease. Neurology. 2017 Jun 06; 88(23):2162-2168. View Abstract
Relationship between white matter connectivity loss and cortical thinning in cerebral amyloid angiopathy. Hum Brain Mapp. 2017 Jul; 38(7):3723-3731. View Abstract
Chaplaincy Visitation and Spiritual Care after Intracerebral Hemorrhage. J Health Care Chaplain. 2017 Oct-Dec; 23(4):156-166. View Abstract
Perihematomal Edema Expansion Rates and Patient Outcomes in Deep and Lobar Intracerebral Hemorrhage. Neurocrit Care. 2017 04; 26(2):205-212. View Abstract
Lymphopenia, Infectious Complications, and Outcome in Spontaneous Intracerebral Hemorrhage. Neurocrit Care. 2017 04; 26(2):160-166. View Abstract
Cortical superficial siderosis and first-ever cerebral hemorrhage in cerebral amyloid angiopathy. Neurology. 2017 Apr 25; 88(17):1607-1614. View Abstract
Dementia incidence and predictors in cerebral amyloid angiopathy patients without intracerebral hemorrhage. J Cereb Blood Flow Metab. 2018 02; 38(2):241-249. View Abstract
Significance of admission hypoalbuminemia in acute intracerebral hemorrhage. J Neurol. 2017 May; 264(5):905-911. View Abstract
MRI-visible perivascular spaces in cerebral amyloid angiopathy and hypertensive arteriopathy. Neurology. 2017 Mar 21; 88(12):1157-1164. View Abstract
First Diagnosis of Atrial Fibrillation at the Time of Stroke. Cerebrovasc Dis. 2017; 43(3-4):192-199. View Abstract
Cost and Utility of Microbiological Cultures Early After Intensive Care Unit Admission for Intracerebral Hemorrhage. Neurocrit Care. 2017 02; 26(1):58-63. View Abstract
Small vessel disease burden in cerebral amyloid angiopathy without symptomatic hemorrhage. Neurology. 2017 Feb 28; 88(9):878-884. View Abstract
Imaging the Acute Formation of a Cortical Microbleed in Cerebral Amyloid Angiopathy. JAMA Neurol. 2017 01 01; 74(1):120-121. View Abstract
Visuospatial Functioning in Cerebral Amyloid Angiopathy: A Pilot Study. J Alzheimers Dis. 2017; 56(4):1223-1227. View Abstract
APP Mutations in Cerebral Amyloid Angiopathy with or without Cortical Calcifications: Report of Three Families and a Literature Review. J Alzheimers Dis. 2017; 56(1):37-46. View Abstract
Cerebrovascular function in presymptomatic and symptomatic individuals with hereditary cerebral amyloid angiopathy: a case-control study. Lancet Neurol. 2017 Feb; 16(2):115-122. View Abstract
Prevention of Stroke in Patients With Silent Cerebrovascular Disease: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2017 Feb; 48(2):e44-e71. View Abstract
Association of Key Magnetic Resonance Imaging Markers of Cerebral Small Vessel Disease With Hematoma Volume and Expansion in Patients With Lobar and Deep Intracerebral Hemorrhage. JAMA Neurol. 2016 Dec 01; 73(12):1440-1447. View Abstract
ß-Amyloid in CSF: Biomarker for preclinical cerebral amyloid angiopathy. Neurology. 2017 Jan 10; 88(2):169-176. View Abstract
Early Magnetic Resonance Imaging and Cognitive Markers of Hereditary Cerebral Amyloid Angiopathy. Stroke. 2016 12; 47(12):3041-3044. View Abstract
Association Between Serum Calcium Level and Extent of Bleeding in Patients With Intracerebral Hemorrhage. JAMA Neurol. 2016 Nov 01; 73(11):1285-1290. View Abstract
Reduced vascular amyloid burden at microhemorrhage sites in cerebral amyloid angiopathy. Acta Neuropathol. 2017 03; 133(3):409-415. View Abstract
Genetic variants in CETP increase risk of intracerebral hemorrhage. Ann Neurol. 2016 11; 80(5):730-740. View Abstract
Cortical superficial siderosis predicts early recurrent lobar hemorrhage. Neurology. 2016 Nov 01; 87(18):1863-1870. View Abstract
Microbleed and microinfarct detection in amyloid angiopathy: a high-resolution MRI-histopathology study. Brain. 2016 12; 139(Pt 12):3151-3162. View Abstract
Microbleeds on MRI are associated with microinfarcts on autopsy in cerebral amyloid angiopathy. Neurology. 2016 Oct 04; 87(14):1488-1492. View Abstract
Florbetapir-PET to diagnose cerebral amyloid angiopathy: A prospective study. Neurology. 2016 Nov 08; 87(19):2043-2049. View Abstract
Noncontrast Computed Tomography Hypodensities Predict Poor Outcome in Intracerebral Hemorrhage Patients. Stroke. 2016 10; 47(10):2511-6. View Abstract
Recurrent hemorrhage risk and mortality in hereditary and sporadic cerebral amyloid angiopathy. Neurology. 2016 Oct 04; 87(14):1482-1487. View Abstract
Intracranial atherosclerosis and cerebral small vessel disease in intracerebral hemorrhage patients. J Neurol Sci. 2016 Oct 15; 369:324-329. View Abstract
Progression of Brain Network Alterations in Cerebral Amyloid Angiopathy. Stroke. 2016 10; 47(10):2470-5. View Abstract
Delayed seizures after intracerebral haemorrhage. Brain. 2016 10; 139(Pt 10):2694-2705. View Abstract
Risk Factors Associated With Early vs Delayed Dementia After Intracerebral Hemorrhage. JAMA Neurol. 2016 08 01; 73(8):969-76. View Abstract
Association Between Hypodensities Detected by Computed Tomography and Hematoma Expansion in Patients With Intracerebral Hemorrhage. JAMA Neurol. 2016 08 01; 73(8):961-8. View Abstract
Total Magnetic Resonance Imaging Burden of Small Vessel Disease in Cerebral Amyloid Angiopathy: An Imaging-Pathologic Study of Concept Validation. JAMA Neurol. 2016 08 01; 73(8):994-1001. View Abstract
CT Angiography Spot Sign, Hematoma Expansion, and Outcome in Primary Pontine Intracerebral Hemorrhage. Neurocrit Care. 2016 08; 25(1):79-85. View Abstract
Hypernatremia at Hospital Discharge and Out of Hospital Mortality Following Primary Intracerebral Hemorrhage. Neurocrit Care. 2016 08; 25(1):110-6. View Abstract
Blood pressure burden and outcome in warfarin-related intracerebral hemorrhage. Int J Stroke. 2016 10; 11(8):898-909. View Abstract
APOE polymorphisms influence longitudinal lipid trends preceding intracerebral hemorrhage. Neurol Genet. 2016 Aug; 2(4):e81. View Abstract
Longitudinal Diffusion Tensor Imaging Detects Recovery of Fractional Anisotropy Within Traumatic Axonal Injury Lesions. Neurocrit Care. 2016 06; 24(3):342-52. View Abstract
Sporadic Cerebral Amyloid Angiopathy: Pathophysiology, Neuroimaging Features, and Clinical Implications. Semin Neurol. 2016 Jun; 36(3):233-43. View Abstract
Effect of CTA Tube Current on Spot Sign Detection and Accuracy for Prediction of Intracerebral Hemorrhage Expansion. AJNR Am J Neuroradiol. 2016 Oct; 37(10):1781-1786. View Abstract
Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study. Lancet Neurol. 2016 07; 15(8):811-819. View Abstract
Cerebral Microbleeds and Cerebrovascular Reactivity in the General Population: The EDAN Study. J Alzheimers Dis. 2016 05 04; 53(2):497-503. View Abstract
Subacute decline in serum lipids precedes the occurrence of primary intracerebral hemorrhage. Neurology. 2016 05 31; 86(22):2034-41. View Abstract
Leukocyte Count and Intracerebral Hemorrhage Expansion. Stroke. 2016 06; 47(6):1473-8. View Abstract
Reliability of intracerebral hemorrhage classification systems: A systematic review. Int J Stroke. 2016 08; 11(6):626-36. View Abstract
Small vessel disease and cognitive impairment: The relevance of central network connections. Hum Brain Mapp. 2016 07; 37(7):2446-54. View Abstract
Cognitive Profile and its Association with Neuroimaging Markers of Non-Demented Cerebral Amyloid Angiopathy Patients in a Stroke Unit. J Alzheimers Dis. 2016 03 08; 52(1):171-8. View Abstract
Embolic Stroke, Atrial Fibrillation, and Microbleeds: Is There a Role for Anticoagulation? Stroke. 2016 Mar; 47(3):904-7. View Abstract
Predicting Intracerebral Hemorrhage Growth With the Spot Sign: The Effect of Onset-to-Scan Time. Stroke. 2016 Mar; 47(3):695-700. View Abstract
Validation of Clinicoradiological Criteria for the Diagnosis of Cerebral Amyloid Angiopathy-Related Inflammation. JAMA Neurol. 2016 Feb; 73(2):197-202. View Abstract
Cortical Superficial Siderosis in Memory Clinic Patients: Further Evidence for Underlying Cerebral Amyloid Angiopathy. Cerebrovasc Dis. 2016; 41(3-4):156-62. View Abstract
Diffusion tensor imaging in acute-to-subacute traumatic brain injury: a longitudinal analysis. BMC Neurol. 2016 Jan 11; 16:2. View Abstract
White matter hyperintensity patterns in cerebral amyloid angiopathy and hypertensive arteriopathy. Neurology. 2016 Feb 09; 86(6):505-11. View Abstract
Ischemic brain injury in cerebral amyloid angiopathy. J Cereb Blood Flow Metab. 2016 Jan; 36(1):40-54. View Abstract
Erratum: Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue. Am J Neurodegener Dis. 2015; 4(2):49. View Abstract
Cerebral amyloid angiopathy severity is linked to dilation of juxtacortical perivascular spaces. J Cereb Blood Flow Metab. 2016 Mar; 36(3):576-80. View Abstract
Role of Vascular Disease in Alzheimer-Like Progressive Cognitive Impairment. Stroke. 2016 Feb; 47(2):577-80. View Abstract
Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis. N Engl J Med. 2015 Oct 08; 373(15):1418-28. View Abstract
Association Between Blood Pressure Control and Risk of Recurrent Intracerebral Hemorrhage. JAMA. 2015 Sep 01; 314(9):904-12. View Abstract
Rate of Contrast Extravasation on Computed Tomographic Angiography Predicts Hematoma Expansion and Mortality in Primary Intracerebral Hemorrhage. Stroke. 2015 Sep; 46(9):2498-503. View Abstract
Statins in Intracerebral Hemorrhage. Curr Atheroscler Rep. 2015 Aug; 17(8):46. View Abstract
Matrix metalloproteinase 9-mediated intracerebral hemorrhage induced by cerebral amyloid angiopathy. Neurobiol Aging. 2015 Nov; 36(11):2963-2971. View Abstract
Estimating Total Cerebral Microinfarct Burden From Diffusion-Weighted Imaging. Stroke. 2015 Aug; 46(8):2129-35. View Abstract
Cortical superficial siderosis: detection and clinical significance in cerebral amyloid angiopathy and related conditions. Brain. 2015 Aug; 138(Pt 8):2126-39. View Abstract
APOE e4 and lipid levels affect risk of recurrent nonlobar intracerebral hemorrhage. Neurology. 2015 Jul 28; 85(4):349-56. View Abstract
Rare Coding Variation and Risk of Intracerebral Hemorrhage. Stroke. 2015 Aug; 46(8):2299-301. View Abstract
The Pathophysiology of Intracerebral Hemorrhage Formation and Expansion. Transl Stroke Res. 2015 Aug; 6(4):257-63. View Abstract
Diagnostic value of lobar microbleeds in individuals without intracerebral hemorrhage. Alzheimers Dement. 2015 Dec; 11(12):1480-1488. View Abstract
Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2015 Jul; 46(7):2032-60. View Abstract
Decoupling of structural and functional brain connectivity in older adults with white matter hyperintensities. Neuroimage. 2015 Aug 15; 117:222-9. View Abstract
COX-2 rs20417 Polymorphism Is Associated with Stroke and White Matter Disease. J Stroke Cerebrovasc Dis. 2015 Aug; 24(8):1817-22. View Abstract
Minocycline reduces spontaneous hemorrhage in mouse models of cerebral amyloid angiopathy. Stroke. 2015 Jun; 46(6):1633-1640. View Abstract
The characteristics of superficial siderosis and convexity subarachnoid hemorrhage and clinical relevance in suspected cerebral amyloid angiopathy. Cerebrovasc Dis. 2015; 39(5-6):278-86. View Abstract
Cerebral amyloid angiopathy with and without hemorrhage: evidence for different disease phenotypes. Neurology. 2015 Mar 24; 84(12):1206-12. View Abstract
Cortical localization of microbleeds in cerebral amyloid angiopathy: an ultra high-field 7T MRI study. J Alzheimers Dis. 2015; 43(4):1325-30. View Abstract
Vascular contributions to cognitive impairment and dementia including Alzheimer's disease. Alzheimers Dement. 2015 Jun; 11(6):710-7. View Abstract
Lobar microbleeds are associated with a decline in executive functioning in older adults. Cerebrovasc Dis. 2014; 38(5):377-83. View Abstract
Structural network alterations and neurological dysfunction in cerebral amyloid angiopathy. Brain. 2015 Jan; 138(Pt 1):179-88. View Abstract
Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2014 Dec; 45(12):3754-832. View Abstract
Mystery case: cerebral amyloid angiopathy-related inflammation. Neurology. 2014 Oct 28; 83(18):1678-9. View Abstract
Interrelationship of superficial siderosis and microbleeds in cerebral amyloid angiopathy. Neurology. 2014 Nov 11; 83(20):1838-43. View Abstract
Spot sign on 90-second delayed computed tomography angiography improves sensitivity for hematoma expansion and mortality: prospective study. Stroke. 2014 Nov; 45(11):3293-7. View Abstract
Warfarin and statins are associated with hematoma volume in primary infratentorial intracerebral hemorrhage. Neurocrit Care. 2014 Oct; 21(2):192-9. View Abstract
APOE e variants increase risk of warfarin-related intracerebral hemorrhage. Neurology. 2014 Sep 23; 83(13):1139-46. View Abstract
CT angiography spot sign in intracerebral hemorrhage predicts active bleeding during surgery. Neurology. 2014 Sep 02; 83(10):883-9. View Abstract
Recommendations of the Alzheimer's disease-related dementias conference. Neurology. 2014 Aug 26; 83(9):851-60. View Abstract
Posterior white matter disease distribution as a predictor of amyloid angiopathy. Neurology. 2014 Aug 26; 83(9):794-800. View Abstract
Cerebral microbleeds in a multiethnic elderly community: demographic and clinical correlates. J Neurol Sci. 2014 Oct 15; 345(1-2):125-30. View Abstract
Cerebral microbleeds are associated with the progression of ischemic vascular lesions. Cerebrovasc Dis. 2014; 37(5):382-8. View Abstract
Incidence of symptomatic hemorrhage in patients with lobar microbleeds. Stroke. 2014 Aug; 45(8):2280-5. View Abstract
Microinfarct disruption of white matter structure: a longitudinal diffusion tensor analysis. Neurology. 2014 Jul 08; 83(2):182-8. View Abstract
Cerebral microbleeds: overview and implications in cognitive impairment. Alzheimers Res Ther. 2014; 6(3):33. View Abstract
Developing biomarkers for cerebral amyloid angiopathy trials: do potential disease phenotypes hold promise? - authors' reply. Lancet Neurol. 2014 Jun; 13(6):540. View Abstract
Risk factors for computed tomography angiography spot sign in deep and lobar intracerebral hemorrhage are shared. Stroke. 2014 Jun; 45(6):1833-5. View Abstract
Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue. Am J Neurodegener Dis. 2014; 3(1):19-32. View Abstract
Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage. Am J Hum Genet. 2014 Apr 03; 94(4):511-21. View Abstract
Anatomic pattern of intracerebral hemorrhage expansion: relation to CT angiography spot sign and hematoma center. Stroke. 2014 Apr; 45(4):1154-6. View Abstract
rTMS for treatment of depression in a patient with cerebral amyloid angiopathy: a case report on safety and efficacy. Brain Stimul. 2014 May-Jun; 7(3):495-7. View Abstract
Outcome markers for clinical trials in cerebral amyloid angiopathy. Lancet Neurol. 2014 Apr; 13(4):419-28. View Abstract
Predicting hematoma expansion after primary intracerebral hemorrhage. JAMA Neurol. 2014 Feb; 71(2):158-64. View Abstract
Cerebral microbleeds and macrobleeds: should they influence our recommendations for antithrombotic therapies? Curr Cardiol Rep. 2013 Dec; 15(12):425. View Abstract
APOE associations with severe CAA-associated vasculopathic changes: collaborative meta-analysis. J Neurol Neurosurg Psychiatry. 2014 Mar; 85(3):300-5. View Abstract
C. Miller fisher: an appreciation. Stroke. 2013 Dec; 44(12):e171-2. View Abstract
A physiologic biomarker for cerebral amyloid angiopathy. Neurology. 2013 Nov 05; 81(19):1650-1. View Abstract
Apolipoprotein E, statins, and risk of intracerebral hemorrhage. Stroke. 2013 Nov; 44(11):3013-7. View Abstract
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol. 2013 Aug; 12(8):822-38. View Abstract
Predictors of hematoma volume in deep and lobar supratentorial intracerebral hemorrhage. JAMA Neurol. 2013 Aug; 70(8):988-94. View Abstract
Acute respiratory distress syndrome after spontaneous intracerebral hemorrhage*. Crit Care Med. 2013 Aug; 41(8):1992-2001. View Abstract
Interstitial fluid drainage is impaired in ischemic stroke and Alzheimer's disease mouse models. Acta Neuropathol. 2013 Sep; 126(3):353-64. View Abstract
Disconnection of the ascending arousal system in traumatic coma. J Neuropathol Exp Neurol. 2013 Jun; 72(6):505-23. View Abstract
Novel insights into the genetics of intracerebral hemorrhage. Stroke. 2013 Jun; 44(6 Suppl 1):S137. View Abstract
Anti-amyloid ß autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies. Ann Neurol. 2013 Apr; 73(4):449-58. View Abstract
Computed tomography angiography spot sign does not predict case fatality in aneurysmal subarachnoid hemorrhage with intraparenchymal extension. Stroke. 2013 Jun; 44(6):1590-4. View Abstract
Heritability estimates identify a substantial genetic contribution to risk and outcome of intracerebral hemorrhage. Stroke. 2013 Jun; 44(6):1578-83. View Abstract
Topography of dilated perivascular spaces in subjects from a memory clinic cohort. Neurology. 2013 Apr 23; 80(17):1551-6. View Abstract
Microbleeds do not affect rate of cognitive decline in Alzheimer disease. Neurology. 2013 Mar 26; 80(13):1266. View Abstract
Estimating cerebral microinfarct burden from autopsy samples. Neurology. 2013 Apr 09; 80(15):1365-9. View Abstract
Hematoma expansion following acute intracerebral hemorrhage. Cerebrovasc Dis. 2013; 35(3):195-201. View Abstract
Cerebral amyloid angiopathy burden associated with leukoaraiosis: a positron emission tomography/magnetic resonance imaging study. Ann Neurol. 2013 Apr; 73(4):529-36. View Abstract
Common variants within oxidative phosphorylation genes influence risk of ischemic stroke and intracerebral hemorrhage. Stroke. 2013 Mar; 44(3):612-9. View Abstract
Burden of blood pressure-related alleles is associated with larger hematoma volume and worse outcome in intracerebral hemorrhage. Stroke. 2013 Feb; 44(2):321-6. View Abstract
Stroke after Alzheimer disease: I have more bad news. Neurology. 2013 Feb 19; 80(8):695-6. View Abstract
Confounding by indication in retrospective studies of intracerebral hemorrhage: antiepileptic treatment and mortality. Neurocrit Care. 2012 Dec; 17(3):361-6. View Abstract
CTA spot sign predicts hematoma expansion in patients with delayed presentation after intracerebral hemorrhage. Neurocrit Care. 2012 Dec; 17(3):421-8. View Abstract
Prolonged emergency department length of stay is not associated with worse outcomes in patients with intracerebral hemorrhage. Neurocrit Care. 2012 Dec; 17(3):334-42. View Abstract
Characteristic distributions of intracerebral hemorrhage-associated diffusion-weighted lesions. Neurology. 2012 Dec 11; 79(24):2335-41. View Abstract
Reducing available soluble ß-amyloid prevents progression of cerebral amyloid angiopathy in transgenic mice. J Neuropathol Exp Neurol. 2012 Nov; 71(11):1009-17. View Abstract
Modeling intracerebral hemorrhage growth and response to anticoagulation. PLoS One. 2012; 7(10):e48458. View Abstract
The pattern and pace of hyperacute hemorrhage expansion. Neurocrit Care. 2012 Oct; 17(2):250-4. View Abstract
Burden of risk alleles for hypertension increases risk of intracerebral hemorrhage. Stroke. 2012 Nov; 43(11):2877-83. View Abstract
The pathophysiology and clinical presentation of cerebral amyloid angiopathy. Curr Atheroscler Rep. 2012 Aug; 14(4):343-50. View Abstract
Predicting sites of new hemorrhage with amyloid imaging in cerebral amyloid angiopathy. Neurology. 2012 Jul 24; 79(4):320-6. View Abstract
Functional magnetic resonance imaging detection of vascular reactivity in cerebral amyloid angiopathy. Ann Neurol. 2012 Jul; 72(1):76-81. View Abstract
Neuroanatomic connectivity of the human ascending arousal system critical to consciousness and its disorders. J Neuropathol Exp Neurol. 2012 Jun; 71(6):531-46. View Abstract
Apolipoprotein E genotype is associated with CT angiography spot sign in lobar intracerebral hemorrhage. Stroke. 2012 Aug; 43(8):2120-5. View Abstract
Apolipoprotein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage. Stroke. 2012 Jun; 43(6):1490-5. View Abstract
TOMM40 in Cerebral Amyloid Angiopathy Related Intracerebral Hemorrhage: Comparative Genetic Analysis with Alzheimer's Disease. Transl Stroke Res. 2012 Jul; 3(Suppl 1):102-12. View Abstract
COL4A1 mutations in patients with sporadic late-onset intracerebral hemorrhage. Ann Neurol. 2012 Apr; 71(4):470-7. View Abstract
Cytokine-like factor 1 gene expression is enriched in idiopathic pulmonary fibrosis and drives the accumulation of CD4+ T cells in murine lungs: evidence for an antifibrotic role in bleomycin injury. Am J Pathol. 2012 May; 180(5):1963-78. View Abstract
Cerebral microinfarcts: the invisible lesions. Lancet Neurol. 2012 Mar; 11(3):272-82. View Abstract
Spot sign score predicts rapid bleeding in spontaneous intracerebral hemorrhage. Emerg Radiol. 2012 Jun; 19(3):195-202. View Abstract
Genetic variation at CR1 increases risk of cerebral amyloid angiopathy. Neurology. 2012 Jan 31; 78(5):334-41. View Abstract
Advances in our Understanding of the Pathophysiology, Detection and Management of Cerebral Amyloid Angiopathy. Eur Neurol Rev. 2012; 7(2):134-139. View Abstract
COL4A2 mutations impair COL4A1 and COL4A2 secretion and cause hemorrhagic stroke. Am J Hum Genet. 2012 Jan 13; 90(1):91-101. View Abstract
Statin use and outcome after intracerebral hemorrhage: case-control study and meta-analysis. Neurology. 2011 Dec 06; 77(23):2073; author reply 2073-4. View Abstract
Cerebral amyloid angiopathy in the elderly. Ann Neurol. 2011 Dec; 70(6):871-80. View Abstract
Cerebrovascular lesions induce transient ß-amyloid deposition. Brain. 2011 Dec; 134(Pt 12):3697-707. View Abstract
Warfarin-related intraventricular hemorrhage: imaging and outcome. Neurology. 2011 Nov 15; 77(20):1840-6. View Abstract
A comparison of acute hemorrhagic stroke outcomes in 2 populations: the Crete-Boston study. Stroke. 2011 Dec; 42(12):3640-2. View Abstract
Cerebral microbleeds and cognitive functioning in the PROSPER study. Neurology. 2011 Oct 11; 77(15):1446-52. View Abstract
Distribution of white matter hyperintensity in cerebral hemorrhage and healthy aging. J Neurol. 2012 Mar; 259(3):530-6. View Abstract
Safety and tolerability of deferoxamine mesylate in patients with acute intracerebral hemorrhage. Stroke. 2011 Nov; 42(11):3067-74. View Abstract
Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke. 2011 Sep; 42(9):2672-713. View Abstract
Body mass index and etiology of intracerebral hemorrhage. Stroke. 2011 Sep; 42(9):2526-30. View Abstract
APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study. Lancet Neurol. 2011 Aug; 10(8):702-9. View Abstract
Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup. Alzheimers Dement. 2011 Jul; 7(4):367-85. View Abstract
Packed red blood cell transfusion and decreased mortality in intracerebral hemorrhage. Neurosurgery. 2011 May; 68(5):1286-92. View Abstract
Correlations between MRI white matter lesion location and executive function and episodic memory. Neurology. 2011 Apr 26; 76(17):1492-9. View Abstract
Sustained disease-activity-free status in patients with relapsing-remitting multiple sclerosis treated with cladribine tablets in the CLARITY study: a post-hoc and subgroup analysis. Lancet Neurol. 2011 Apr; 10(4):329-37. View Abstract
Cerebral amyloid angiopathy: a systematic review. J Clin Neurol. 2011 Mar; 7(1):1-9. View Abstract
Statin use and outcome after intracerebral hemorrhage: case-control study and meta-analysis. Neurology. 2011 May 03; 76(18):1581-8. View Abstract
Ischemic-appearing electrocardiographic changes predict myocardial injury in patients with intracerebral hemorrhage. Am J Emerg Med. 2012 May; 30(4):545-52. View Abstract
Life imitates art: anti-amyloid antibodies and inflammatory cerebral amyloid angiopathy. Neurology. 2011 Mar 01; 76(9):772-3. View Abstract
Intracerebral hematoma expansion: making predictions (about the future). Neurology. 2011 Apr 05; 76(14):1204-5. View Abstract
The effect of survival bias on case-control genetic association studies of highly lethal diseases. Circ Cardiovasc Genet. 2011 Apr; 4(2):188-96. View Abstract
Statin use following intracerebral hemorrhage: a decision analysis. Arch Neurol. 2011 May; 68(5):573-9. View Abstract
Moving the tipping point: the decision to anticoagulate patients with atrial fibrillation. Circ Cardiovasc Qual Outcomes. 2011 Jan 01; 4(1):14-21. View Abstract
Variants at APOE influence risk of deep and lobar intracerebral hemorrhage. Ann Neurol. 2010 Dec; 68(6):934-43. View Abstract
MK-0633, a potent 5-lipoxygenase inhibitor, in chronic obstructive pulmonary disease. Respir Med. 2011 Mar; 105(3):392-401. View Abstract
Screening for familial APP mutations in sporadic cerebral amyloid angiopathy. PLoS One. 2010 Nov 11; 5(11):e13949. View Abstract
White matter hyperintensity volume is increased in small vessel stroke subtypes. Neurology. 2010 Nov 09; 75(19):1670-7. View Abstract
Lack of replication in polymorphisms reported to be associated with atrial fibrillation. Heart Rhythm. 2011 Mar; 8(3):403-9. View Abstract
Should anticoagulation be resumed after intracerebral hemorrhage? Cleve Clin J Med. 2010 Nov; 77(11):791-9. View Abstract
Personalized approaches to clopidogrel therapy: are we there yet? Stroke. 2010 Dec; 41(12):2997-3002. View Abstract
Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy. Neurology. 2010 Oct 26; 75(17):1571; author reply 1571. View Abstract
Spatial relation between microbleeds and amyloid deposits in amyloid angiopathy. Ann Neurol. 2010 Oct; 68(4):545-8. View Abstract
Intracerebral hemorrhage: introduction. Stroke. 2010 Oct; 41(10 Suppl):S91. View Abstract
Common mitochondrial sequence variants in ischemic stroke. Ann Neurol. 2011 Mar; 69(3):471-80. View Abstract
Prior antiplatelet therapy and outcome following intracerebral hemorrhage: a systematic review. Neurology. 2010 Oct 12; 75(15):1333-42. View Abstract
Independent susceptibility markers for atrial fibrillation on chromosome 4q25. Circulation. 2010 Sep 07; 122(10):976-84. View Abstract
MRI markers of small vessel disease in lobar and deep hemispheric intracerebral hemorrhage. Stroke. 2010 Sep; 41(9):1933-8. View Abstract
Guidelines for the management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2010 Sep; 41(9):2108-29. View Abstract
Case records of the Massachusetts General Hospital. Case 22-2010. An 87-year-old woman with dementia and a seizure. N Engl J Med. 2010 Jul 22; 363(4):373-81. View Abstract
Principal-component analysis for assessment of population stratification in mitochondrial medical genetics. Am J Hum Genet. 2010 Jun 11; 86(6):904-17. View Abstract
Prevalence of superficial siderosis in patients with cerebral amyloid angiopathy. Neurology. 2010 Apr 27; 74(17):1346-50. View Abstract
Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits. Am J Pathol. 2010 Apr; 176(4):1841-54. View Abstract
Comparison of hematoma shape and volume estimates in warfarin versus non-warfarin-related intracerebral hemorrhage. Neurocrit Care. 2010 Feb; 12(1):30-4. View Abstract
Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy. Neurology. 2010 Jan 05; 74(1):93; author reply 93. View Abstract
Differential recognition of vascular and parenchymal beta amyloid deposition. Neurobiol Aging. 2011 Oct; 32(10):1774-83. View Abstract
Red meets white: do microbleeds link hemorrhagic and ischemic cerebrovascular disease? Neurology. 2009 Nov 17; 73(20):1614-5. View Abstract
Cerebrospinal fluid amyloid beta(40) is decreased in cerebral amyloid angiopathy. Ann Neurol. 2009 Aug; 66(2):245-9. View Abstract
Descriptive analysis of the Boston criteria applied to a Dutch-type cerebral amyloid angiopathy population. Stroke. 2009 Sep; 40(9):3022-7. View Abstract
CT angiography for intracerebral hemorrhage does not increase risk of acute nephropathy. Stroke. 2009 Jul; 40(7):2393-7. View Abstract
Microbleeds versus macrobleeds: evidence for distinct entities. Stroke. 2009 Jul; 40(7):2382-6. View Abstract
Beta-amyloid, blood vessels, and brain function. Stroke. 2009 Jul; 40(7):2601-6. View Abstract
Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice. J Neurochem. 2009 Jun; 109(6):1636-47. View Abstract
Silent ischemic infarcts are associated with hemorrhage burden in cerebral amyloid angiopathy. Neurology. 2009 Apr 07; 72(14):1230-5. View Abstract
Anemia and hematoma volume in acute intracerebral hemorrhage. Crit Care Med. 2009 Apr; 37(4):1442-7. View Abstract
Should we test for CYP2C9 before initiating anticoagulant therapy in patients with atrial fibrillation? J Gen Intern Med. 2009 May; 24(5):543-9. View Abstract
Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol. 2009 Feb; 8(2):165-74. View Abstract
Plasma Abeta, homocysteine, and cognition: the Vitamin Intervention for Stroke Prevention (VISP) trial. Neurology. 2009 Jan 20; 72(3):268-72. View Abstract
Cost-effectiveness of using pharmacogenetic information in warfarin dosing for patients with nonvalvular atrial fibrillation. Ann Intern Med. 2009 Jan 20; 150(2):73-83. View Abstract
Association of subdural hematoma with increased mortality in lobar intracerebral hemorrhage. Arch Neurol. 2009 Jan; 66(1):79-84. View Abstract
Intracerebral hemorrhage. Handb Clin Neurol. 2009; 93:767-90. View Abstract
MR imaging detection of cerebral microbleeds: effect of susceptibility-weighted imaging, section thickness, and field strength. AJNR Am J Neuroradiol. 2009 Feb; 30(2):338-43. View Abstract
Detection of isolated cerebrovascular beta-amyloid with Pittsburgh compound B. Ann Neurol. 2008 Nov; 64(5):587-91. View Abstract
Impaired visual evoked flow velocity response in cerebral amyloid angiopathy. Neurology. 2008 Oct 28; 71(18):1424-30. View Abstract
Patient-specific decision-making for warfarin therapy in nonvalvular atrial fibrillation: how will screening with genetics and imaging help? Stroke. 2008 Dec; 39(12):3308-15. View Abstract
Risk of thromboembolism following acute intracerebral hemorrhage. Neurocrit Care. 2009; 10(1):28-34. View Abstract
Management of intracerebral hemorrhage. Curr Atheroscler Rep. 2008 Aug; 10(4):324-31. View Abstract
A new Thr49Pro transthyretin gene mutation associated with leptomeningeal amyloidosis. J Neurol Sci. 2008 Sep 15; 272(1-2):186-90. View Abstract
Prediction of functional outcome in patients with primary intracerebral hemorrhage: the FUNC score. Stroke. 2008 Aug; 39(8):2304-9. View Abstract
Statins, low cholesterol, and hemorrhagic stroke: an uncertain triangle. Neurology. 2008 Jun 10; 70(24 Pt 2):2355-6. View Abstract
The genetic architecture of intracerebral hemorrhage. Stroke. 2008 Jul; 39(7):2166-73. View Abstract
Tissue microstructural changes are independently associated with cognitive impairment in cerebral amyloid angiopathy. Stroke. 2008 Jul; 39(7):1988-92. View Abstract
Effect of statins on intracerebral hemorrhage outcome and recurrence. Stroke. 2008 Jul; 39(7):2151-4. View Abstract
Spatial distribution of white-matter hyperintensities in Alzheimer disease, cerebral amyloid angiopathy, and healthy aging. Stroke. 2008 Apr; 39(4):1127-33. View Abstract
Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia. Arch Neurol. 2008 Jan; 65(1):94-100. View Abstract
Cardiac-resynchronization therapy in heart failure with narrow QRS complexes. N Engl J Med. 2007 Dec 13; 357(24):2461-71. View Abstract
Imaging of amyloid burden and distribution in cerebral amyloid angiopathy. Ann Neurol. 2007 Sep; 62(3):229-34. View Abstract
Contrast extravasation on CT angiography predicts hematoma expansion in intracerebral hemorrhage. Neurology. 2007 Aug 07; 69(6):617; author reply 617. View Abstract
Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy. Brain. 2007 Sep; 130(Pt 9):2310-9. View Abstract
Variants conferring risk of atrial fibrillation on chromosome 4q25. Nature. 2007 Jul 19; 448(7151):353-7. View Abstract
Course of cerebral amyloid angiopathy-related inflammation. Neurology. 2007 Apr 24; 68(17):1411-6. View Abstract
Contrast extravasation on CT angiography predicts hematoma expansion in intracerebral hemorrhage. Neurology. 2007 Mar 20; 68(12):889-94. View Abstract
A 63-year-old man with headaches and behavioral deterioration. Neurology. 2007 Mar 06; 68(10):782-7. View Abstract
Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report. Arch Neurol. 2007 Mar; 64(3):431-4. View Abstract
Antibody-mediated clearance of amyloid-beta peptide from cerebral amyloid angiopathy revealed by quantitative in vivo imaging. J Neurosci. 2007 Feb 21; 27(8):1973-80. View Abstract
Acute evaluation of programmer-guided AV/PV and VV delay optimization comparing an IEGM method and echocardiogram for cardiac resynchronization therapy in heart failure patients and dual-chamber ICD implants. J Cardiovasc Electrophysiol. 2007 Feb; 18(2):185-91. View Abstract
Validation of intracranial area as a surrogate measure of intracranial volume when using clinical MRI. J Neuroimaging. 2007 Jan; 17(1):74-7. View Abstract
Early edema in warfarin-related intracerebral hemorrhage. Neurocrit Care. 2007; 7(1):58-63. View Abstract
Myeloid dendritic cells in inclusion-body myositis and polymyositis. Muscle Nerve. 2007 Jan; 35(1):17-23. View Abstract
Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease. Neurobiol Dis. 2006 Dec; 24(3):516-24. View Abstract
A phase 2 study of tramiprosate for cerebral amyloid angiopathy. Alzheimer Dis Assoc Disord. 2006 Oct-Dec; 20(4):269-74. View Abstract
Is "compassionate use" compassionate?: rFVIIa for intracerebral hemorrhage. Neurology. 2006 Sep 26; 67(6):934-5. View Abstract
Effects of apoE isoforms on beta-amyloid-induced matrix metalloproteinase-9 in rat astrocytes. Brain Res. 2006 Sep 21; 1111(1):222-6. View Abstract
ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages. J Cell Biol. 2006 Aug 14; 174(4):547-56. View Abstract
Progression of white matter lesions and hemorrhages in cerebral amyloid angiopathy. Neurology. 2006 Jul 11; 67(1):83-7. View Abstract
Nonexcitatory, cardiac contractility modulation electrical impulses: feasibility study for advanced heart failure in patients with normal QRS duration. Heart Rhythm. 2006 Oct; 3(10):1140-7. View Abstract
White matter alterations in cerebral amyloid angiopathy measured by diffusion tensor imaging. Stroke. 2006 Jul; 37(7):1759-64. View Abstract
Imaging of hemorrhagic stroke. Magn Reson Imaging Clin N Am. 2006 May; 14(2):127-40, v. View Abstract
Small vessels, big problems. N Engl J Med. 2006 Apr 06; 354(14):1451-3. View Abstract
Reply: To PMID 16374827. Ann Neurol. 2006 Feb; 59(2):432. View Abstract
Antiplatelet use after intracerebral hemorrhage. Neurology. 2006 Jan 24; 66(2):206-9. View Abstract
Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease. J Neurosci. 2006 Jan 11; 26(2):365-71. View Abstract
Plasma beta-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy. Neurology. 2006 Jan 10; 66(1):23-9. View Abstract
Current pharmacotherapy for Alzheimer's disease. Annu Rev Med. 2006; 57:513-33. View Abstract
The cerebral beta-amyloid angiopathies: hereditary and sporadic. Brain Pathol. 2006 Jan; 16(1):30-9. View Abstract
Treatment and prevention of primary intracerebral hemorrhage. Semin Neurol. 2005 Dec; 25(4):445-52. View Abstract
Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease. Neurology. 2005 Nov 08; 65(9):1402-8. View Abstract
A randomized blinded trial of combination therapy with cyclophosphamide in patients-with active multiple sclerosis on interferon beta. Mult Scler. 2005 Oct; 11(5):573-82. View Abstract
The phosphodiesterase puzzlebox: PDE4D and stroke. Ann Neurol. 2005 Sep; 58(3):345-6. View Abstract
Spatial clustering of hemorrhages in probable cerebral amyloid angiopathy. Ann Neurol. 2005 Sep; 58(3):459-62. View Abstract
Progression of cerebral amyloid angiopathy in transgenic mouse models of Alzheimer disease. J Neuropathol Exp Neurol. 2005 Jul; 64(7):588-94. View Abstract
Hemorrhagic stroke. Neuroimaging Clin N Am. 2005 May; 15(2):259-72, ix. View Abstract
Prevalence and effects of lobar microhemorrhages in early-stage dementia. Neurodegener Dis. 2005; 2(6):305-12. View Abstract
Prevention and Treatment of Intracerebral Hemorrhage. Seminars in Neurology, in press. . 2005. View Abstract
Advanced age, anticoagulation intensity, and risk for intracranial hemorrhage among patients taking warfarin for atrial fibrillation. Ann Intern Med. 2004 Nov 16; 141(10):745-52. View Abstract
White matter lesions, cognition, and recurrent hemorrhage in lobar intracerebral hemorrhage. Neurology. 2004 Nov 09; 63(9):1606-12. View Abstract
Amyloid angiopathy-related vascular cognitive impairment. Stroke. 2004 Nov; 35(11 Suppl 1):2616-9. View Abstract
Warfarin, hematoma expansion, and outcome of intracerebral hemorrhage. Neurology. 2004 Sep 28; 63(6):1059-64. View Abstract
The effect of warfarin and intensity of anticoagulation on outcome of intracerebral hemorrhage. Arch Intern Med. 2004 Apr 26; 164(8):880-4. View Abstract
Hemorrhage burden predicts recurrent intracerebral hemorrhage after lobar hemorrhage. Stroke. 2004 Jun; 35(6):1415-20. View Abstract
Clinical manifestations of cerebral amyloid angiopathy-related inflammation. Ann Neurol. 2004 Feb; 55(2):250-6. View Abstract
Serial imaging of cerebral amyloid angiopathy progression in transgenic mice with multiphoton microscopy. Soc Neurosci Abs. 2004. View Abstract
The relationship of age and anticoagulant intensity to risk of intracranial hemorrhage among patients taking warfarin for atrial fibrillation. Ann Int Med. 2004; (141):745-752. View Abstract
Cerebral amyloid angiopathy. Mohr JP, Choi D, Grotta JC, Weir B, Wolf PA (eds) Stroke: Pathophysiology, Diagnosis and Management. 2004; 693-705. View Abstract
Gradient-echo MRI suggests a high prevalence of cerebral amyloid angiopathy hemorrhages in patients evaluated for dementia. American Neurological Association. 2004. View Abstract
Homocysteine, brain atrophy, and white matter disease in Alzheimer’s disease and cerebral amyloid angiopathy. American Neurological Association. 2004. View Abstract
Phase II Study of Cerebril, a candidate treatment for intracerebral hemorrhage related to cerebral amyloid angiopathy. Neurology (abs). 2004. View Abstract
Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Curr Atheroscler Rep. 2003 Jul; 5(4):260-6. View Abstract
Can patients be anticoagulated after intracerebral hemorrhage? A decision analysis. Stroke. 2003 Jul; 34(7):1710-6. View Abstract
Hemorrhagic stroke associated with the Iowa amyloid precursor protein mutation. Neurology. 2003 Mar 25; 60(6):1020-2. View Abstract
Alzheimer disease's double-edged vaccine. Nat Med. 2003 Apr; 9(4):389-90. View Abstract
Progression of cerebral amyloid angiopathy in superficial vessels demonstrated by whole brain multiphoton imaging. Soc Neurosci Abs. 2003. View Abstract
Abeta species, including IsoAsp23 Abeta, in Iowa-type familial cerebral amyloid angiopathy. Acta Neuropathol. 2003 Mar; 105(3):252-8. View Abstract
Vascular changes in Iowa-type hereditary cerebral amyloid angiopathy. Ann N Y Acad Sci. 2002 Nov; 977:245-51. View Abstract
Genetics of primary intracerebral hemorrhage. J Stroke Cerebrovasc Dis. 2002 Sep-Oct; 11(5):265-71. View Abstract
Leukoaraiosis is associated with warfarin-related hemorrhage following ischemic stroke. Neurology. 2002 Jul 23; 59(2):193-7. View Abstract
Cerebral amyloid angiopathy and dementia: two amyloids are worse than one. Neurology. 2002 Jun 11; 58(11):1587-8. View Abstract
Beyond hypertension: unraveling the causes of intracerebral hemorrhage. Stroke. 2002 May; 33(5):1195-6. View Abstract
Cerebral amyloid angiopathy and vessel dysfunction. Cerebrovasc Dis. 2002; 13 Suppl 2:42-7. View Abstract
Dynamic single-section CT demonstrates reduced cerebral blood flow in acute intracerebral hemorrhage. Cerebrovasc Dis. 2002; 14(3-4):214-20. View Abstract
Cerebral amyloid angiopathy and vascular dysfunction. Cerebrovasc Disease. 2002; (13 (suppl 2)):42-47. View Abstract
Dynamic single-section contrast CT measures cerebral blood flow in acute intracerebral hemorrhage. . Cerebrovasc Disease. 2002; (14):214-220. View Abstract
Cerebral amyloid angiopathy and vascular dysfunction. Cerebrovascular Disease. 2002; (13 (suppl 2)):42-47. View Abstract
Pathogenic effects of D23N Iowa mutant amyloid beta -protein. J Biol Chem. 2001 Aug 31; 276(35):32860-6. View Abstract
The effects of AbetaPP mutations and APOE polymorphisms on cerebral amyloid angiopathy. Amyloid. 2001 Jul; 8 Suppl 1:43-7. View Abstract
Outcome markers for clinical trials in cerebral amyloid angiopathy. Amyloid. 2001 Jul; 8 Suppl 1:56-60. View Abstract
First international conference on cerebral amyloid angiopathy, October 5-6, 2000, Boston, MA. Amyloid. 2001 Jun; 8(2):143-6. View Abstract
Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy. Ann Neurol. 2001 Jun; 49(6):697-705. View Abstract
Quantitation of apoE domains in Alzheimer disease brain suggests a role for apoE in Abeta aggregation. J Neuropathol Exp Neurol. 2001 Apr; 60(4):342-9. View Abstract
Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Neurology. 2001 Feb 27; 56(4):537-9. View Abstract
First international conference on cerebral amyloid angiopathy,. Amyloid: Int J Exp Clin Invest. 2001; (8):143-146. View Abstract
Pathogenic effects of D23N “Iowa” mutant amyloid ß-protein. . J Biol Chem. 2001; (276):32860-32866. View Abstract
Clinical diagnosis of cerebral amyloid angiopathy. Validation of the Boston criteria. Neurology. 2001; (56): 537-539. View Abstract
Outcome markers for clinical trials in cerebral amyloid angiopathy. Amyloid: Int J Exp Clin Invest. 2001; (8 (suppl 1)):56-60. View Abstract
The effects of AßPP mutations and APOE polymorphisms on cerebral amyloid angiopathy. Amyloid: Int J Exp Clin Invest. 2001; (8 (suppl 1)):43-47. View Abstract
Warfarin-associated hemorrhage and cerebral amyloid angiopathy: a genetic and pathologic study. Neurology. 2000 Oct 10; 55(7):947-51. View Abstract
Plasma beta-amyloid peptide, transforming growth factor-beta 1, and risk for cerebral amyloid angiopathy. Ann N Y Acad Sci. 2000 Apr; 903:144-9. View Abstract
Apolipoprotein E genotype and the risk of recurrent lobar intracerebral hemorrhage. N Engl J Med. 2000 Jan 27; 342(4):240-5. View Abstract
Donepezil therapy in clinical practice: a randomized crossover study. Arch Neurol. 2000 Jan; 57(1):94-9. View Abstract
Clinical aspects and diagnostic criteria of sporadic CAA-related hemorrhage. Cerebrovascular Amyloidosis in Alzheimer's Disease and Related Disorders. 2000; 3-19. View Abstract
Apolipoprotein E genotype and risk of recurrent lobar intracerebal hemorrhage. New Engl J Med. 2000; (342):240-245. View Abstract
Plasma ß-amyloid peptide, transforming growth factor-ß1, and risk for cerebral amyloid angiopathy. Ann NY Acad Sci. 2000; (903):144-149. View Abstract
Cerebral amyloid angiopathy. The Neurologist. 2000; (6):315-325. View Abstract
A genetic and pathological study. . Neurology. 2000; (55):947-955. View Abstract
MRI detection of new hemorrhages: potential marker of progression in cerebral amyloid angiopathy. Neurology. 1999 Sep 22; 53(5):1135-8. View Abstract
Lack of independent associations of apolipoprotein E promoter and intron 1 polymorphisms with Alzheimer's disease. Neurosci Lett. 1999 Sep 17; 272(3):155-8. View Abstract
YopJ of Yersinia spp. is sufficient to cause downregulation of multiple mitogen-activated protein kinases in eukaryotic cells. Infect Immun. 1999 Feb; 67(2):708-16. View Abstract
Low cholesterol as a risk factor for primary intracerebral hemorrhage: A case-control study. Neuroepidemiology. 1999; 18(4):185-93. View Abstract
MRI detection of new hemorrhages. Potential marker of progression in cerebral amyloid angiopathy. 1999; (53):1135-1138. View Abstract
Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. Hum Mol Genet. 1998 Nov; 7(12):1953-6. View Abstract
Involvement of guanosine triphosphatases and phospholipase C-gamma2 in extracellular signal-regulated kinase, c-Jun NH2-terminal kinase, and p38 mitogen-activated protein kinase activation by the B cell antigen receptor. J Exp Med. 1998 Oct 05; 188(7):1287-95. View Abstract
Cerebral amyloid angiopathy: prospects for clinical diagnosis and treatment. Neurology. 1998 Sep; 51(3):690-4. View Abstract
Association of apolipoprotein E epsilon2 and vasculopathy in cerebral amyloid angiopathy. Neurology. 1998 Apr; 50(4):961-5. View Abstract
Progression of cerebral amyloid angiopathy: accumulation of amyloid-beta40 in affected vessels. J Neuropathol Exp Neurol. 1998 Apr; 57(4):353-9. View Abstract
Intracranial hemorrhage. Textbook of Neurology. 1998. View Abstract
Diagnosis of cerebral amyloid angiopathy. Sensitivity and specificity of cortical biopsy. Stroke. 1997 Jul; 28(7):1418-22. View Abstract
Cerebral amyloid angiopathy and apolipoprotein E: bad news for the good allele? Ann Neurol. 1997 Jun; 41(6):701-2. View Abstract
Amyloid angiopathy. Neurology. 1997 Jan; 48(1):291. View Abstract
Atlas of Clinical Neurology. 1997. View Abstract
Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease. Ann N Y Acad Sci. 1996 Dec 16; 802:1-5. View Abstract
Apolipoprotein E epsilon 4 is associated with the presence and earlier onset of hemorrhage in cerebral amyloid angiopathy. Stroke. 1996 Aug; 27(8):1333-7. View Abstract
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-1996. Cerebral hemorrhage in a 69-year-old woman receiving warfarin. N Engl J Med. 1996 07 18; 335(3):189-96. View Abstract
Petechial hemorrhages accompanying lobar hemorrhage: detection by gradient-echo MRI. Neurology. 1996 Jun; 46(6):1751-4. View Abstract
Lack of association of trinucleotide repeat polymorphisms in very-low-density lipoprotein receptor gene with Alzheimer's disease. Ann Neurol. 1996 Jun; 39(6):800-3. View Abstract
Angiotensin-converting enzyme gene and lacunar stroke. Stroke. 1996 Mar; 27(3):569-70. View Abstract
Cellular signaling pathways and cytoskeletal organization. Ann N Y Acad Sci. 1996 Jan 17; 777:114-20. View Abstract
Lack of association of trinucleotide repeat polymorphisms in the VLDL receptor gene with Alzheimer disease. Annal of Neurology. 1996; (6):800-803. View Abstract
Continuum: Dementia Care. American Academy of Neurology. 1996. View Abstract
Case records of the Massachusetts General Hospital. New Engl J Med. 1996; (335):189-196. View Abstract
Amino-terminal region of the beta-amyloid precursor protein activates mitogen-activated protein kinase. Neurosci Lett. 1995 Sep 22; 198(1):52-6. View Abstract
Apolipoprotein E epsilon 4 and cerebral hemorrhage associated with amyloid angiopathy. Ann Neurol. 1995 Aug; 38(2):254-9. View Abstract
The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation. J Exp Med. 1995 Jul 01; 182(1):219-31. View Abstract
Secreted beta-APP stimulates MAP kinase and phosphorylation of tau in neurons. Neurobiol Aging. 1995 May-Jun; 16(3):403-7; discussion 407-8. View Abstract
Linking amyloid precursor protein processing and tau-related pathology in Alzheimer's disease. Alzheimer's Disease: Lessons from Cell Biology. 1995. View Abstract
Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation. Proc Natl Acad Sci U S A. 1994 Jul 19; 91(15):7104-8. View Abstract
Secreted ß-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation. Proc Natl Acad Sci USA. 1994; (91):7104-7108.. View Abstract
Tau proteins and Alzheimer's disease. Alzheimer Disease. 1994. View Abstract
The clinical spectrum of cerebral amyloid angiopathy: presentations without lobar hemorrhage. Neurology. 1993 Oct; 43(10):2073-9. View Abstract
The clinical spectrum of cerebral amyloid angiopathy: Presentations without lobar hemorrhage. Neurology. 1993; (43):2073-2079.. View Abstract
Lipoxin generation by human megakaryocyte-induced 12-lipoxygenase. Biochim Biophys Acta. 1992 Jan 13; 1133(2):223-34. View Abstract
Hematopoietic factor-induced synthesis of von Willebrand factor by the Dami human megakaryoblastic cell line and by normal human megakaryocytes. Exp Hematol. 1991 Jan; 19(1):53-8. View Abstract
Transforming growth factor beta inhibits endomitosis in the Dami human megakaryocytic cell line. Blood. 1990 Aug 01; 76(3):533-7. View Abstract
Turtles all the way down: Some molecular mechanisms underlying long-term sensitization in Aplysia. Neural Models of Plasticity. 1989. View Abstract
Characterization of a new megakaryocytic cell line: the Dami cell. Blood. 1988 Dec; 72(6):1968-77. View Abstract
A molecular mechanism for long-term sensitization in Aplysia. Nature. 1987 Sep 3-9; 329(6134):62-5. View Abstract
Molecular mechanisms for memory: second-messenger induced modifications of protein kinases in nerve cells. Annu Rev Neurosci. 1987; 10:459-76. View Abstract
Distribution of cAMP and cAMP-dependent protein kinases in Aplysia sensory neurons. J Neurosci. 1987 Jan; 7(1):291-301. View Abstract
Abundant expression of ras proteins in Aplysia neurons. J Cell Biol. 1986 Aug; 103(2):485-92. View Abstract
Structural studies on a family of cAMP-binding proteins in the nervous system of Aplysia. J Cell Biol. 1986 Jan; 102(1):320-31. View Abstract

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