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Researcher | Research Overview

Serine Avagyan uses the zebrafish to study the onset of clonal blood disorders due to acquired and germline mutations. She conducts her studies by introducing mutations into fluorescently labeled blood stem cells and tracking mutant stem cell clones over time. Through this innovative approach, she has discovered the critical role of inflammation in maintaining the fitness of mutant clones that allows them to expand relative to normal cells. Dr Avagyan also studies the origin of pediatric bone marrow failure and leukemia associated with germline predisposition conditions, such as GATA2 deficiency and RUNX1-familial platelet disorder.

Researcher | Research Background

Serine Avagyan received her MD and PhD degrees from Mount Sinai School of Medicine of New York University. She completed residency at the Children's Hospital of New York-Presbyterian at Columbia University Medical Center in New York, and clinical fellowship at the Dana-Farber/Boston Children's Hospital Cancer and Blood Disorders Center in Boston. She is an attending physician in the Bone Marrow Failure and MDS Program and in Pediatric Stem Cell Transplantation.

Researcher | Publications