ABOUT THE RESEARCHER

BACKGROUND

Dr. Ong is an Assistant Professor at the Department of Population Medicine, Harvard Pilgrim Health Care and Harvard Medical School. She received her PhD in health informatics at the University of New South Wales, Sydney, Australia, and her postdoctoral training at the Boston Children’s Hospital Computational Health Informatics Program.

Dr. Ong’s research combines clinical epidemiology and big data analytics to study disease epidemiology and treatment patterns. Her research interest focuses broadly on leveraging electronic health data to characterize disease phenotypes and risk factors, and to investigate gaps and barriers to evidence-based treatment.

PUBLICATIONS

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  1. New-onset Hypogammaglobulinemia and Infectious Complications Associated with Rituximab Use in Childhood-onset Rheumatic Diseases. Rheumatology (Oxford). 2021 Jul 30. View abstract
  2. Improved Disease Course Associated With Early Initiation of Biologics in Polyarticular Juvenile Idiopathic Arthritis: Trajectory Analysis of a Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans Study. Arthritis Rheumatol. 2021 Jun 08. View abstract
  3. Rituximab-induced hypogammaglobulinemia and infection risk in pediatric patients. J Allergy Clin Immunol. 2021 Aug; 148(2):523-532.e8. View abstract
  4. Geographical Distribution, Incidence, Malignancies, and Outcome of 136 Eastern Slavic Patients With Nijmegen Breakage Syndrome and NBN Founder Variant c.657_661del5. Front Immunol. 2020; 11:602482. View abstract
  5. Socioeconomic status and survival in patients with pulmonary hypertension. ERJ Open Res. 2020 Oct; 6(4). View abstract
  6. Claims-Based Algorithms for Identifying Patients With Pulmonary Hypertension: A Comparison of Decision Rules and Machine-Learning Approaches. J Am Heart Assoc. 2020 10 20; 9(19):e016648. View abstract
  7. Urban-Rural Disparities in Pulmonary Hypertension Mortality. Ann Am Thorac Soc. 2020 09; 17(9):1168-1171. View abstract
  8. Risk factors for suicide attempt in children, adolescents, and young adults hospitalized for mental health disorders. Child Adolesc Ment Health. 2021 05; 26(2):134-142. View abstract
  9. Gastrointestinal manifestations in common variable immunodeficiency (CVID) are associated with an altered immunophenotype including B- and T-cell dysregulation. J Allergy Clin Immunol Pract. 2020 04; 8(4):1436-1438.e1. View abstract
  10. Rising Prevalence of Comorbid Alcohol and Opioid Use Disorders in Adolescents and Young Adults in the United States. J Gen Intern Med. 2019 10; 34(10):1987-1989. View abstract
  11. Racial and Ethnic Differences in Pediatric Pulmonary Hypertension: An Analysis of the Pediatric Pulmonary Hypertension Network Registry. J Pediatr. 2019 08; 211:63-71.e6. View abstract
  12. A Bayesian Network Approach to Disease Subtype Discovery. Methods Mol Biol. 2019; 1939:299-322. View abstract
  13. Association of Immunoglobulin Levels, Infectious Risk, and Mortality With Rituximab and Hypogammaglobulinemia. JAMA Netw Open. 2018 11 02; 1(7):e184169. View abstract
  14. Delay in reviewing test results prolongs hospital length of stay: a retrospective cohort study. BMC Health Serv Res. 2018 05 16; 18(1):369. View abstract
  15. Common Variable Immunodeficiency Non-Infectious Disease Endotypes Redefined Using Unbiased Network Clustering in Large Electronic Datasets. Front Immunol. 2017; 8:1740. View abstract
  16. Learning a Comorbidity-Driven Taxonomy of Pediatric Pulmonary Hypertension. Circ Res. 2017 Aug 04; 121(4):341-353. View abstract
  17. Conclusions in systematic reviews of mammography for breast cancer screening and associations with review design and author characteristics. Syst Rev. 2017 05 22; 6(1):105. View abstract
  18. Trends in Prostate-Specific Antigen Screening and Prostate Cancer Interventions 3 Years After the U.S. Preventive Services Task Force Recommendation. Ann Intern Med. 2017 03 21; 166(6):451-452. View abstract
  19. The Impact of Provider Networks on the Co-Prescriptions of Interacting Drugs: A Claims-Based Analysis. Drug Saf. 2017 03; 40(3):263-272. View abstract
  20. Trends in Pharmacologic Interventions for Preventing Recurrence of Crohn's Disease After Ileocolonic Surgery. Inflamm Bowel Dis. 2016 10; 22(10):2432-41. View abstract
  21. Erratum to: Provider patient-sharing networks and multiple-provider prescribing of benzodiazepines. J Gen Intern Med. 2016 May; 31(5):588. View abstract
  22. Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies. Virology. 2016 07; 494:236-47. View abstract
  23. Mammography Risks: The Authors Reply. Health Aff (Millwood). 2016 Mar; 35(3):552. View abstract
  24. New Guidelines For Breast Cancer Screening. Health Aff (Millwood). 2016 Jan; 35(1):180. View abstract
  25. Health IT for Patient Safety and Improving the Safety of Health IT. Stud Health Technol Inform. 2016; 222:25-36. View abstract
  26. Measuring the effects of computer downtime on hospital pathology processes. J Biomed Inform. 2016 Feb; 59:308-15. View abstract
  27. A Review on the Bioinformatics Tools for Neuroimaging. Malays J Med Sci. 2015 Dec; 22(Spec Issue):9-19. View abstract
  28. Provider Patient-Sharing Networks and Multiple-Provider Prescribing of Benzodiazepines. J Gen Intern Med. 2016 Feb; 31(2):164-171. View abstract
  29. Breast Cancer Diagnoses: The Authors Reply. Health Aff (Millwood). 2015 Jul; 34(7):1253. View abstract
  30. National expenditure for false-positive mammograms and breast cancer overdiagnoses estimated at $4 billion a year. Health Aff (Millwood). 2015 Apr; 34(4):576-83. View abstract
  31. Clinical safety of England's national programme for IT: a retrospective analysis of all reported safety events 2005 to 2011. Int J Med Inform. 2015 Mar; 84(3):198-206. View abstract
  32. Using social connection information to improve opinion mining: Identifying negative sentiment about HPV vaccines on Twitter. Stud Health Technol Inform. 2015; 216:761-5. View abstract
  33. Population-level evidence for an autoimmune etiology of epilepsy. JAMA Neurol. 2014 May; 71(5):569-74. View abstract
  34. Consequences of antibiotics and infections in infancy: bugs, drugs, and wheezing. Ann Allergy Asthma Immunol. 2014 May; 112(5):441-445.e1. View abstract
  35. Communication interventions to improve adherence to infection control precautions: a randomised crossover trial. BMC Infect Dis. 2013 Feb 06; 13:72. View abstract
  36. Syndromic surveillance for health information system failures: a feasibility study. J Am Med Inform Assoc. 2013 May 01; 20(3):506-12. View abstract
  37. Last Orders: Follow-up of Tests Ordered on the Day of Hospital Discharge. Arch Intern Med. 2012 Sep 24; 172(17):1347-9. View abstract
  38. Let's Just Check That Potassium One More Time . . . : Comment on "Last Orders: Follow-up of Tests Ordered on the Day of Hospital Discharge". Arch Intern Med. 2012 Sep 24; 172(17):1344-53. View abstract
  39. Automated identification of extreme-risk events in clinical incident reports. J Am Med Inform Assoc. 2012 Jun; 19(e1):e110-8. View abstract
  40. Patient safety problems associated with heathcare information technology: an analysis of adverse events reported to the US Food and Drug Administration. AMIA Annu Symp Proc. 2011; 2011:853-7. View abstract
  41. Evaluating the effectiveness of clinical alerts: a signal detection approach. AMIA Annu Symp Proc. 2011; 2011:1036-44. View abstract
  42. Using FDA reports to inform a classification for health information technology safety problems. J Am Med Inform Assoc. 2012 Jan-Feb; 19(1):45-53. View abstract
  43. A systematic review of failures in handoff communication during intrahospital transfers. Jt Comm J Qual Patient Saf. 2011 Jun; 37(6):274-84. View abstract
  44. A simulation framework for mapping risks in clinical processes: the case of in-patient transfers. J Am Med Inform Assoc. 2011 May 01; 18(3):259-66. View abstract
  45. An analysis of computer-related patient safety incidents to inform the development of a classification. J Am Med Inform Assoc. 2010 Nov-Dec; 17(6):663-70. View abstract
  46. Automated categorisation of clinical incident reports using statistical text classification. Qual Saf Health Care. 2010 Dec; 19(6):e55. View abstract
  47. Safety through redundancy: a case study of in-hospital patient transfers. Qual Saf Health Care. 2010 Oct; 19(5):e32. View abstract
  48. Low serum folate and vitamin B-6 are associated with an altered cancellous bone structure in humans. Am J Clin Nutr. 2009 Nov; 90(5):1440-5. View abstract