Information

Related Research Units

Nephrology Research

Education

Undergraduate School

Williams College
1981 Williamstown MA

Medical School

University of Vermont College of Medicine
1985 Burlington VT

Internship

Pediatrics Mayo Clinic
1986 Rochester MN

Residency

Pediatrics Mayo Clinic
1988 Rochester MN

Fellowship

Pediatric Nephrology Boston Children's Hospital
1993 Boston MA

Publications

  1. Understanding Rare Kidney Stone Diseases: A Review. Am J Kidney Dis. 2025 May 16. View Abstract
  2. Rapid Weight Gain After Pediatric Kidney Transplant and Development of Cardiometabolic Risk Factors Among Children Enrolled in the North American Pediatric Renal Trials and Collaborative Studies Cohort. Pediatr Transplant. 2025 Feb; 29(1):e70005. View Abstract
  3. Predictors of Posttransplant Lymphoproliferative Disease in Pediatric Patients. Laryngoscope. 2025 Jun; 135(6):2182-2189. View Abstract
  4. Influence of season, sex, and interspecific interactions on the diel activity patterns of two sympatric African small carnivores. Sci Rep. 2024 11 29; 14(1):29701. View Abstract
  5. Water provisioning shapes carnivore community structure. Trends Ecol Evol. 2024 Dec; 39(12):1070-1072. View Abstract
  6. Profuse diarrhea after autologous stem cell transplantation for peripheral T-cell lymphoma, not otherwise specified: a case report. Acta Gastroenterol Belg. 2024 Oct-Dec; 87(4):527-530. View Abstract
  7. Clinical characteristics and favorable treatment responses of recurrent focal segmental glomerulosclerosis or steroid-resistant nephrotic syndrome in children after kidney transplantation. Pediatr Nephrol. 2024 Nov; 39(11):3317-3331. View Abstract
  8. Diagnosis and management of primary hyperoxalurias: best practices. Pediatr Nephrol. 2024 Nov; 39(11):3143-3155. View Abstract
  9. Expanding the spectrum of novel candidate genes using trio exome sequencing and identification of monogenic cause in 27.5% of 320 families with steroid-resistant nephrotic syndrome. Genes Dis. 2025 Mar; 12(2):101280. View Abstract
  10. Using the multivariate Hawkes process to study interactions between multiple species from camera trap data. Ecology. 2024 Apr; 105(4):e4237. View Abstract
  11. The bii4africa dataset of faunal and floral population intactness estimates across Africa's major land uses. Sci Data. 2024 Feb 12; 11(1):191. View Abstract
  12. Prospective Study of the Multisite Spread of a Medication Safety Intervention: Factors Common to Hospitals With Improved Outcomes. Am J Med Qual. 2024 Jan-Feb 01; 39(1):21-32. View Abstract
  13. Post-transplant recurrence of focal segmental glomerular sclerosis: consensus statements. Kidney Int. 2024 Mar; 105(3):450-463. View Abstract
  14. Prevalence of mycophenolate mofetil discontinuation and subsequent outcomes in pediatric kidney transplant recipients: A PNRC study. Pediatr Transplant. 2024 02; 28(1):e14628. View Abstract
  15. Correction to: Outcomes based on induction regimens in pediatric kidney transplantation: a NAPRTCS and PHIS collaborative study. Pediatr Nephrol. 2023 Oct; 38(10):3503. View Abstract
  16. Temporal partitioning and the potential for avoidance behaviour within South African carnivore communities. Ecol Evol. 2023 Aug; 13(8):e10380. View Abstract
  17. Ensuring our exstrophy-epispadias complex patients and families thrive. Pediatr Nephrol. 2024 Feb; 39(2):371-382. View Abstract
  18. Optimal Care for Kidney Health: Development of a Merit-based Incentive Payment System (MIPS) Value Pathway. J Am Soc Nephrol. 2023 08 01; 34(8):1315-1328. View Abstract
  19. Why humans kill animals and why we cannot avoid it. Sci Total Environ. 2023 Oct 20; 896:165283. View Abstract
  20. Clinical course and management of children with IgA vasculitis with nephritis. Pediatr Nephrol. 2023 11; 38(11):3721-3733. View Abstract
  21. Outcomes based on induction regimens in pediatric kidney transplantation: a NAPRTCS and PHIS collaborative study. Pediatr Nephrol. 2023 10; 38(10):3455-3464. View Abstract
  22. Position statement on the management of the immune checkpoint inhibitor-induced colitis via multidisciplinary modified Delphi consensus. Eur J Cancer. 2023 07; 187:36-57. View Abstract
  23. Evaluating Kidney Function Decline in Children with Chronic Kidney Disease Using a Multi-Institutional Electronic Health Record Database. Clin J Am Soc Nephrol. 2023 02 01; 18(2):173-182. View Abstract
  24. Primary Hyperoxaluria: A Need for New Perspectives in an Era of New Therapies. Am J Kidney Dis. 2023 Feb; 81(2):131-133. View Abstract
  25. Skeletal Outcomes in Children and Young Adults with Glomerular Disease. J Am Soc Nephrol. 2022 12; 33(12):2233-2246. View Abstract
  26. Survival of neonates born with kidney failure during the initial hospitalization. Pediatr Nephrol. 2023 02; 38(2):583-591. View Abstract
  27. Treatment of primary hyperoxaluria type 1. Clin Kidney J. 2022 May; 15(Suppl 1):i9-i13. View Abstract
  28. Treatment of post-transplant recurrent FSGS in children using plasmapheresis and augmentation of immunosuppression. BMC Nephrol. 2022 04 05; 23(1):131. View Abstract
  29. Reverse phenotyping facilitates disease allele calling in exome sequencing of patients with CAKUT. Genet Med. 2022 02; 24(2):307-318. View Abstract
  30. The Pediatric Nephrology Workforce Crisis: A Call to Action. J Pediatr. 2021 12; 239:5-10.e4. View Abstract
  31. Continued reduction in peritonitis rates in pediatric dialysis centers: results of the Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) Collaborative. Pediatr Nephrol. 2021 08; 36(8):2383-2391. View Abstract
  32. Children with CKD Are Not Little Adults with CKD: Pediatric Considerations for the Advancing American Kidney Health Initiative. Clin J Am Soc Nephrol. 2021 03 08; 16(3):470-472. View Abstract
  33. Species distribution modelling of Bryde's whales, humpback whales, southern right whales, and sperm whales in the southern African region to inform their conservation in expanding economies. PeerJ. 2020; 8:e9997. View Abstract
  34. Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. Am J Hum Genet. 2020 10 01; 107(4):727-742. View Abstract
  35. Lions Panthera leo Prefer Killing Certain Cattle Bos taurus Types. Animals (Basel). 2020 Apr 16; 10(4). View Abstract
  36. Early outcomes comparing induction with antithymocyte globulin vs alemtuzumab in two steroid-avoidance protocols in pediatric renal transplantation. Pediatr Transplant. 2020 05; 24(3):e13685. View Abstract
  37. Measuring Quality in Kidney Care: An Evaluation of Existing Quality Metrics and Approach to Facilitating Improvements in Care Delivery. J Am Soc Nephrol. 2020 03; 31(3):602-614. View Abstract
  38. Electronic Alerts to Identify Acute Kidney Injury in Children: Promises and Pitfalls. J Pediatr. 2020 05; 220:9-11. View Abstract
  39. Using Electronic Health Record Data to Rapidly Identify Children with Glomerular Disease for Clinical Research. J Am Soc Nephrol. 2019 12; 30(12):2427-2435. View Abstract
  40. Effects of changes in adult erythropoietin dosing guidelines on erythropoietin dosing practices, anemia, and blood transfusion in children on hemodialysis: findings from North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS). Pediatr Nephrol. 2020 02; 35(2):297-303. View Abstract
  41. A prospective multi-center quality improvement initiative (NINJA) indicates a reduction in nephrotoxic acute kidney injury in hospitalized children. Kidney Int. 2020 03; 97(3):580-588. View Abstract
  42. Evidence-based development of a nephrotoxic medication list to screen for acute kidney injury risk in hospitalized children. Am J Health Syst Pharm. 2019 10 30; 76(22):1869-1874. View Abstract
  43. Renal replacement therapy in the management of intoxications in children: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) workgroup. Pediatr Nephrol. 2019 11; 34(11):2427-2448. View Abstract
  44. Deconstructing compassionate conservation. Conserv Biol. 2019 08; 33(4):760-768. View Abstract
  45. Mutations in KIRREL1, a slit diaphragm component, cause steroid-resistant nephrotic syndrome. Kidney Int. 2019 10; 96(4):883-889. View Abstract
  46. Infection-Related Glomerulonephritis. Pediatr Clin North Am. 2019 02; 66(1):59-72. View Abstract
  47. Whole-Exome Sequencing Enables a Precision Medicine Approach for Kidney Transplant Recipients. J Am Soc Nephrol. 2019 02; 30(2):201-215. View Abstract
  48. Grazing by large savanna herbivores indirectly alters ant diversity and promotes resource monopolisation. PeerJ. 2019; 7:e6226. View Abstract
  49. Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract. J Am Soc Nephrol. 2018 09; 29(9):2348-2361. View Abstract
  50. Exit site and tunnel infections in children on chronic peritoneal dialysis: findings from the Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) Collaborative. Pediatr Nephrol. 2018 06; 33(6):1029-1035. View Abstract
  51. Whole Exome Sequencing Reveals a Monogenic Cause of Disease in ˜43% of 35 Families With Midaortic Syndrome. Hypertension. 2018 04; 71(4):691-699. View Abstract
  52. Ethical Considerations Concerning Amnioinfusions for Treating Fetal Bilateral Renal Agenesis. Obstet Gynecol. 2018 01; 131(1):130-134. View Abstract
  53. Whole Exome Sequencing of Patients with Steroid-Resistant Nephrotic Syndrome. Clin J Am Soc Nephrol. 2018 01 06; 13(1):53-62. View Abstract
  54. Whole exome sequencing frequently detects a monogenic cause in early onset nephrolithiasis and nephrocalcinosis. Kidney Int. 2018 01; 93(1):204-213. View Abstract
  55. Analysis of 24 genes reveals a monogenic cause in 11.1% of cases with steroid-resistant nephrotic syndrome at a single center. Pediatr Nephrol. 2018 02; 33(2):305-314. View Abstract
  56. Randomized Clinical Trial Design to Assess Abatacept in Resistant Nephrotic Syndrome. Kidney Int Rep. 2018 Jan; 3(1):115-121. View Abstract
  57. Responsiveness of the PROMIS® measures to changes in disease status among pediatric nephrotic syndrome patients: a Midwest pediatric nephrology consortium study. Health Qual Life Outcomes. 2017 Aug 23; 15(1):166. View Abstract
  58. Clinical outcomes and survival in pediatric patients initiating chronic dialysis: a report of the NAPRTCS registry. Pediatr Nephrol. 2017 Dec; 32(12):2319-2330. View Abstract
  59. Tracking data from nine free-roaming Cheetahs (Acinonyx jubatus) collared in the Thabazimbi area, Limpopo Province, South Africa. Biodivers Data J. 2017; (5):e11323. View Abstract
  60. Simplified large African carnivore density estimators from track indices. PeerJ. 2016; 4:e2662. View Abstract
  61. Dialysis in Children and Adolescents: The Pediatric Nephrology Perspective. Am J Kidney Dis. 2017 Feb; 69(2):278-286. View Abstract
  62. Diet of otters (Lutra lutra) in various habitat types in the Pannonian biogeographical region compared to other regions of Europe. PeerJ. 2016; 4:e2266. View Abstract
  63. IMAGES IN CLINICAL MEDICINE. A Child with Gross Hematuria. N Engl J Med. 2015 Aug 27; 373(9):e11. View Abstract
  64. Wildlife Abundance and Diversity as Indicators of Tourism Potential in Northern Botswana. PLoS One. 2015; 10(8):e0135595. View Abstract
  65. Efficacy of galactose and adalimumab in patients with resistant focal segmental glomerulosclerosis: report of the font clinical trial group. BMC Nephrol. 2015 Jul 22; 16:111. View Abstract
  66. Relative availability of natural prey versus livestock predicts landscape suitability for cheetahs Acinonyx jubatus in Botswana. PeerJ. 2015; 3:e1033. View Abstract
  67. Functional Responses of Retaliatory Killing versus Recreational Sport Hunting of Leopards in South Africa. PLoS One. 2015; 10(4):e0125539. View Abstract
  68. The impact of disease duration on quality of life in children with nephrotic syndrome: a Midwest Pediatric Nephrology Consortium study. Pediatr Nephrol. 2015 Sep; 30(9):1467-76. View Abstract
  69. Arteriovenous access monitoring with ultrasound dilution in a pediatric hemodialysis unit. Blood Purif. 2015; 39(1-3):93-8. View Abstract
  70. Safety considerations of mammalian target of rapamycin inhibitors in tuberous sclerosis complex and renal transplantation. J Clin Pharmacol. 2015 Apr; 55(4):368-76. View Abstract
  71. Multidisciplinary consensus on the classification of prenatal and postnatal urinary tract dilation (UTD classification system). J Pediatr Urol. 2014 Dec; 10(6):982-98. View Abstract
  72. Diagnosis and management of glycogen storage disease type I: a practice guideline of the American College of Medical Genetics and Genomics. Genet Med. 2014 Nov; 16(11):e1. View Abstract
  73. A single-gene cause in 29.5% of cases of steroid-resistant nephrotic syndrome. J Am Soc Nephrol. 2015 Jun; 26(6):1279-89. View Abstract
  74. Landscape suitability in Botswana for the conservation of its six large African carnivores. PLoS One. 2014; 9(6):e100202. View Abstract
  75. Trophic scaling and occupancy analysis reveals a lion population limited by top-down anthropogenic pressure in the Limpopo National Park, Mozambique. PLoS One. 2014; 9(6):e99389. View Abstract
  76. Space use of African wild dogs in relation to other large carnivores. PLoS One. 2014; 9(6):e98846. View Abstract
  77. Space use as an indicator of enclosure appropriateness in African wild dogs (Lycaon pictus). J Appl Anim Welf Sci. 2014; 17(2):98-110. View Abstract
  78. Medication reconciliation and therapy management in dialysis-dependent patients: need for a systematic approach. Clin J Am Soc Nephrol. 2013 Nov; 8(11):1988-99. View Abstract
  79. KDOQI US commentary on the 2012 KDIGO clinical practice guideline for glomerulonephritis. Am J Kidney Dis. 2013 Sep; 62(3):403-41. View Abstract
  80. Apheresis therapy in children: an overview of key technical aspects and a review of experience in pediatric renal disease. J Clin Apher. 2013 Feb; 28(1):36-47. View Abstract
  81. Continuous renal replacement therapy for children =10 kg: a report from the prospective pediatric continuous renal replacement therapy registry. J Pediatr. 2013 Mar; 162(3):587-592.e3. View Abstract
  82. Nonrenal indications for continuous renal replacement therapy: A report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group. Pediatr Crit Care Med. 2012 Sep; 13(5):e299-304. View Abstract
  83. Inbreeding avoidance influences the viability of reintroduced populations of African wild dogs (Lycaon pictus). PLoS One. 2012; 7(5):e37181. View Abstract
  84. Novel therapies for resistant focal segmental glomerulosclerosis (FONT) phase II clinical trial: study design. BMC Nephrol. 2011 Feb 10; 12:8. View Abstract
  85. Fluid overload and mortality in children receiving continuous renal replacement therapy: the prospective pediatric continuous renal replacement therapy registry. Am J Kidney Dis. 2010 Feb; 55(2):316-25. View Abstract
  86. Case records of the Massachusetts General Hospital. Case 23-2009. A 13-year-old boy with headache, nausea, seizures, and hypertension. N Engl J Med. 2009 Jul 23; 361(4):389-400. View Abstract
  87. Diversity and depletions in continental carnivore guilds: implications for prioritizing global carnivore conservation. Biol Lett. 2009 Feb 23; 5(1):35-8. View Abstract
  88. A position statement on kidney disease from powdered infant formula-based melamine exposure in Chinese infants. Pediatr Nephrol. 2009 Jul; 24(7):1263-6. View Abstract
  89. Protein and calorie prescription for children and young adults receiving continuous renal replacement therapy: a report from the Prospective Pediatric Continuous Renal Replacement Therapy Registry Group. Crit Care Med. 2008 Dec; 36(12):3239-45. View Abstract
  90. Dynamics of a small re-introduced population of wild dogs over 25 years: Allee effects and the implications of sociality for endangered species' recovery. Oecologia. 2008 Nov; 158(2):239-47. View Abstract
  91. Outcome of management strategies for BK virus replication in pediatric renal transplant recipients. Pediatr Transplant. 2008 Mar; 12(2):180-6. View Abstract
  92. Continuous renal replacement therapy (CRRT) after stem cell transplantation. A report from the prospective pediatric CRRT Registry Group. Pediatr Nephrol. 2008 Apr; 23(4):625-30. View Abstract
  93. Short- and long-term efficacy of levamisole as adjunctive therapy in childhood nephrotic syndrome. Pediatr Nephrol. 2008 Apr; 23(4):575-80. View Abstract
  94. The effect of vascular access location and size on circuit survival in pediatric continuous renal replacement therapy: a report from the PPCRRT registry. Int J Artif Organs. 2007 Dec; 30(12):1116-21. View Abstract
  95. Demographic characteristics of pediatric continuous renal replacement therapy: a report of the prospective pediatric continuous renal replacement therapy registry. Clin J Am Soc Nephrol. 2007 Jul; 2(4):732-8. View Abstract
  96. Focal and segmental glomerulosclerosis in children: a longitudinal assessment. Pediatr Nephrol. 2007 Aug; 22(8):1159-66. View Abstract
  97. Central nervous system lymphoproliferative disorder in pediatric kidney transplant recipients. Pediatr Transplant. 2006 Jun; 10(4):505-12. View Abstract
  98. Multi-centre evaluation of anticoagulation in patients receiving continuous renal replacement therapy (CRRT). Nephrol Dial Transplant. 2005 Jul; 20(7):1416-21. View Abstract
  99. Pediatric patients with multi-organ dysfunction syndrome receiving continuous renal replacement therapy. Kidney Int. 2005 Feb; 67(2):653-8. View Abstract
  100. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 11-2004. A boy with rash, edema, and hypertension. N Engl J Med. 2004 Apr 08; 350(15):1550-9. View Abstract
  101. Effects of fire and fire intensity on the germination and establishment of Acacia karroo, Acacia nilotica, Acacia luederitzii and Dichrostachys cinerea in the field. BMC Ecol. 2004 Apr 07; 4:3. View Abstract
  102. The Prospective Pediatric Continuous Renal Replacement Therapy (ppCRRT) Registry: design, development and data assessed. Int J Artif Organs. 2004 Jan; 27(1):9-14. View Abstract
  103. Hypertension in adolescents: a review of diagnosis and management. Curr Opin Pediatr. 2003 Aug; 15(4):370-8. View Abstract
  104. Serum cardiac troponin and subclinical cardiac status in pediatric chronic renal failure. Pediatrics. 2003 Jul; 112(1 Pt 1):79-86. View Abstract
  105. Continuous renal replacement therapy in children up to 10 kg. Am J Kidney Dis. 2003 May; 41(5):984-9. View Abstract
  106. Utility of hemodialysis in maple syrup urine disease. Pediatr Nephrol. 2002 Apr; 17(4):239-42. View Abstract
  107. Amniotic fluid insulin at 14-20 weeks' gestation: association with later maternal glucose intolerance and birth macrosomia. Diabetes Care. 2001 Jul; 24(7):1259-63. View Abstract
  108. Predictors for abnormal voiding cystourethrography in pediatric patients undergoing renal transplant evaluation. Pediatr Transplant. 2001 Apr; 5(2):99-104. View Abstract
  109. Decreased urinary citrate excretion in type 1a glycogen storage disease. J Pediatr. 2001 Mar; 138(3):378-82. View Abstract
  110. Acyclovir prophylaxis of varicella in children with renal disease receiving steroids. Pediatr Nephrol. 2000 Apr; 14(4):305-8. View Abstract
  111. A high-sensitivity assay for amniotic fluid insulin at 14-20 weeks' gestation. Obstet Gynecol. 1999 Nov; 94(5 Pt 1):778-82. View Abstract
  112. Acute interstitial nephritis presenting as presumed minimal change nephrotic syndrome. Pediatr Nephrol. 1998 Sep; 12(7):576-8. View Abstract
  113. Autosomal dominant distal renal tubular acidosis is associated in three families with heterozygosity for the R589H mutation in the AE1 (band 3) Cl-/HCO3- exchanger. J Biol Chem. 1998 Mar 13; 273(11):6380-8. View Abstract
  114. IgG antineutrophil cytoplasmic antibodies in IgA nephropathy: a clinical variant? Am J Kidney Dis. 1998 Feb; 31(2):341-4. View Abstract
  115. Immune response to Escherichia coli O157:H7 in hemolytic uremic syndrome following salmonellosis. Pediatr Nephrol. 1997 Aug; 11(4):488-90. View Abstract
  116. Renovascular hypertension in Marfan syndrome. Pediatr Nephrol. 1997 Aug; 11(4):499-501. View Abstract
  117. Interactions of ultrapure bovine hemoglobin with renal epithelial cells in vivo and in vitro. Am J Physiol. 1997 Jul; 273(1 Pt 2):F38-52. View Abstract
  118. Phosphorylation of aquaporin-2 does not alter the membrane water permeability of rat papillary water channel-containing vesicles. J Biol Chem. 1996 Mar 08; 271(10):5552-7. View Abstract
  119. Non-nephrotic children with membranoproliferative glomerulonephritis: are steroids indicated? Pediatr Nephrol. 1995 Apr; 9(2):140-4. View Abstract
  120. Permeability properties of rat renal lysosomes. Am J Physiol. 1994 Jan; 266(1 Pt 1):C121-33. View Abstract
  121. Heterogeneous effects of nitroglycerin on the conductance and resistance coronary arterial vasculature. Am J Physiol. 1993 Jun; 264(6 Pt 2):H1960-8. View Abstract
  122. Exposure to an aeroallergen as a possible precipitating factor in respiratory arrest in young patients with asthma. N Engl J Med. 1991 Feb 07; 324(6):359-63. View Abstract
  123. Analysis of the binding of glyceraldehyde-3-phosphate dehydrogenase to microtubules, the mechanism of bundle formation and the linkage effect. Eur J Biochem. 1990 Oct 24; 193(2):437-44. View Abstract

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