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Researcher | Research Overview

Dr. Arbab’s focus is to study causes of neurodegeneration using genome editing tools in cell and animal models, and to develop new gene-based therapeutic strategies that may one day treat genetic neurological diseases in patients.

Researcher | Research Background

Dr. Arbab is the Lodish Family Assistant Professor of Neurology at Harvard Medical School, and faculty member of the Rosamund Stone Zander Translational Neuroscience Center at Boston Children’s Hospital. She received her PhD in Regenerative Medicine at the Hubrecht Institute in The Netherlands and completed an NWO Rubicon postdoctoral fellowship at the Broad Institute with Prof. David Liu, where she developed high-throughput CRISPR assays to characterize genome-editing tools in mammalian cells and predict genome editing outcomes. She has applied these insights to treat genetic neurological disorders with genome editing therapeutics in cells and in mice. In 2021, Manda was awarded a Pathway to Independence Award from the NIH National Institute of Neurological Disorders and Stroke.

Researcher | Publications