ABOUT THE RESEARCHER

OVERVIEW

As a neurosurgeon, one goal of Joseph Madsen's research is to combine clinical research and basic research -- using data from the former in the latter. For example, the study of human electrocorticograms recorded during behavioral cortical tasks is used to answer basic questions about cortical physiology. It is also used to point the way toward safer surgery to control epilepsy by improving the ability to map cortical function. This opportunity is uniquely available because of the need for and benefits of neurosurgical intervention. Advanced technologies, such as digital signal processing (DSP), wavelet analysis, and cutting-edge cognitive science combine in this new laboratory.

He and colleagues are also studying the role of electrostimulation of the vagal nerve in the treatment of epilepsy.

BACKGROUND

Joseph Madsen received his MD from Harvard Medical School and the Harvard-MIT Division of Health Sciences and Technology. He completed an internship at Beth Israel Deaconess Medical Center, a residency at Massachusetts General Hospital, and a fellowship at Beth Israel Deaconess Medical Center.

PUBLICATIONS

Publications powered by Harvard Catalyst Profiles

  1. Microscale Physiological Events on the Human Cortical Surface. Cereb Cortex. 2021 Mar 22. View abstract
  2. Noninvasive Mapping of Ripple Onset Predicts Outcome in Epilepsy Surgery. Ann Neurol. 2021 Mar 12. View abstract
  3. Travelling spindles create necessary conditions for spike-timing-dependent plasticity in humans. Nat Commun. 2021 02 15; 12(1):1027. View abstract
  4. Anesthetic management and outcomes for MRI-guided laser interstitial thermal therapy (LITT) for seizure focus in pediatrics: A single-centre experience with 10 consecutive patients. Paediatr Anaesth. 2021 Feb; 31(2):234-236. View abstract
  5. Magnetic resonance imaging-guided laser-induced thermal therapy for functional hemispherotomy in a child with refractory epilepsy and multiple medical comorbidities. J Neurosurg Pediatr. 2020 Oct 23; 1-6. View abstract
  6. Diagnostic Accuracy of Non-Invasive Thermal Evaluation of Ventriculoperitoneal Shunt Flow in Shunt Malfunction: A Prospective, Multi-Site, Operator-Blinded Study. Neurosurgery. 2020 10 15; 87(5):939-948. View abstract
  7. Drug-Responsive Inhomogeneous Cortical Modulation by Direct Current Stimulation. Ann Neurol. 2020 09; 88(3):489-502. View abstract
  8. A Standardized Electrode Nomenclature for Stereoelectroencephalography Applications. J Clin Neurophysiol. 2020 Jul 23. View abstract
  9. Corpus Callosotomy for Refractory Epilepsy in Aicardi Syndrome: Case Report and Focused Review of the Literature. World Neurosurg. 2020 10; 142:450-455. View abstract
  10. A Noninvasive Retrograde Flushing System for Shunted Hydrocephalus: Initial Case Series of 25 Patients. Cureus. 2020 Jul 01; 12(7):e8940. View abstract
  11. In situ clearance of a proximal shunt malfunction in a child with hydrocephalus post cerebral arteriovenous malformation rupture noted intraoperatively. Surg Neurol Int. 2020; 11:116. View abstract
  12. Pilot Study of Neurodevelopmental Impact of Early Epilepsy Surgery in Tuberous Sclerosis Complex. Pediatr Neurol. 2020 08; 109:39-46. View abstract
  13. Posterior-onset Rasmussen's encephalitis with ipsilateral cerebellar atrophy and uveitis resistant to rituximab. Epilepsy Behav Rep. 2020; 14:100360. View abstract
  14. Scalp ripples as prognostic biomarkers of epileptogenicity in pediatric surgery. Ann Clin Transl Neurol. 2020 03; 7(3):329-342. View abstract
  15. Ictal and interictal source imaging on intracranial EEG predicts epilepsy surgery outcome in children with focal cortical dysplasia. Clin Neurophysiol. 2020 03; 131(3):734-743. View abstract
  16. Lesion-Constrained Electrical Source Imaging: A Novel Approach in Epilepsy Surgery for Tuberous Sclerosis Complex. J Clin Neurophysiol. 2020 Jan; 37(1):79-86. View abstract
  17. Neural Interactions Underlying Visuomotor Associations in the Human Brain. Cereb Cortex. 2019 12 17; 29(11):4551-4567. View abstract
  18. Noninvasive Thermal Evaluation of Ventriculoperitoneal Shunt Patency and Cerebrospinal Fluid Flow Using a Flow Enhancing Device. Neurosurgery. 2019 08 01; 85(2):240-249. View abstract
  19. Intracortical neural activity distal to seizure-onset-areas predicts human focal seizures. PLoS One. 2019; 14(7):e0211847. View abstract
  20. Noninvasive Localization of High-Frequency Oscillations in Children with Epilepsy: Validation against Intracranial Gold-Standard. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul; 2019:1555-1558. View abstract
  21. White matter mean diffusivity correlates with myelination in tuberous sclerosis complex. Ann Clin Transl Neurol. 2019 07; 6(7):1178-1190. View abstract
  22. Early Detection of Human Epileptic Seizures Based on Intracortical Microelectrode Array Signals. IEEE Trans Biomed Eng. 2020 03; 67(3):817-831. View abstract
  23. Assessing the localization accuracy and clinical utility of electric and magnetic source imaging in children with epilepsy. Clin Neurophysiol. 2019 04; 130(4):491-504. View abstract
  24. Delay differential analysis for dynamical sleep spindle detection. J Neurosci Methods. 2019 03 15; 316:12-21. View abstract
  25. Simulating human sleep spindle MEG and EEG from ion channel and circuit level dynamics. J Neurosci Methods. 2019 03 15; 316:46-57. View abstract
  26. Surgical resection of ripple onset predicts outcome in pediatric epilepsy. Ann Neurol. 2018 09; 84(3):331-346. View abstract
  27. Magnetoencephalographic Mapping of Epileptic Spike Population Using Distributed Source Analysis: Comparison With Intracranial Electroencephalographic Spikes. J Clin Neurophysiol. 2018 Jul; 35(4):339-345. View abstract
  28. Somatic SLC35A2 variants in the brain are associated with intractable neocortical epilepsy. Ann Neurol. 2018 06; 83(6):1133-1146. View abstract
  29. Magnetoencephalographic Spike Analysis in Patients With Focal Cortical Dysplasia: What Defines a "Dipole Cluster"? Pediatr Neurol. 2018 06; 83:25-31. View abstract
  30. Heterogeneous Origins of Human Sleep Spindles in Different Cortical Layers. J Neurosci. 2018 03 21; 38(12):3013-3025. View abstract
  31. Superficial Slow Rhythms Integrate Cortical Processing in Humans. Sci Rep. 2018 02 01; 8(1):2055. View abstract
  32. VEGF Signaling in Neurological Disorders. Int J Mol Sci. 2018 Jan 17; 19(1). View abstract
  33. Granger Causality Analysis of Interictal iEEG Predicts Seizure Focus and Ultimate Resection. Neurosurgery. 2018 Jan 01; 82(1):99-109. View abstract
  34. Somatic Mutations Activating the mTOR Pathway in Dorsal Telencephalic Progenitors Cause a Continuum of Cortical Dysplasias. Cell Rep. 2017 12 26; 21(13):3754-3766. View abstract
  35. What is changing when: Decoding visual information in movies from human intracranial recordings. Neuroimage. 2018 10 15; 180(Pt A):147-159. View abstract
  36. Human seizures couple across spatial scales through travelling wave dynamics. Nat Commun. 2017 04 04; 8:14896. View abstract
  37. Current and Emerging Potential of Magnetoencephalography in the Detection and Localization of High-Frequency Oscillations in Epilepsy. Front Neurol. 2017; 8:14. View abstract
  38. Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics. Cancer Cell. 2017 01 09; 31(1):142-156. View abstract
  39. Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy. J Vis Exp. 2016 12 06; (118). View abstract
  40. Neuroimaging of Children With Surgically Treated Hydrocephalus: A Practical Approach. AJR Am J Roentgenol. 2017 Feb; 208(2):413-419. View abstract
  41. Somatic GNAQ Mutation is Enriched in Brain Endothelial Cells in Sturge-Weber Syndrome. Pediatr Neurol. 2017 02; 67:59-63. View abstract
  42. Active delineation of Meyer's loop using oriented priors through MAGNEtic tractography (MAGNET). Hum Brain Mapp. 2017 01; 38(1):509-527. View abstract
  43. Direct current stimulation induces mGluR5-dependent neocortical plasticity. Ann Neurol. 2016 08; 80(2):233-46. View abstract
  44. Rasmussen encephalitis tissue transfer program. Epilepsia. 2016 06; 57(6):1005-7. View abstract
  45. Excess HB-EGF, which promotes VEGF signaling, leads to hydrocephalus. Sci Rep. 2016 05 31; 6:26794. View abstract
  46. Cascade of neural processing orchestrates cognitive control in human frontal cortex. Elife. 2016 Feb 18; 5. View abstract
  47. The role of simulation in neurosurgery. Childs Nerv Syst. 2016 Jan; 32(1):43-54. View abstract
  48. Demonstration that a new flow sensor can operate in the clinical range for cerebrospinal fluid flow. Sens Actuators A Phys. 2015 Oct 01; 234:223-231. View abstract
  49. Combining task-evoked and spontaneous activity to improve pre-operative brain mapping with fMRI. Neuroimage. 2016 Jan 01; 124(Pt A):714-723. View abstract
  50. Microscale spatiotemporal dynamics during neocortical propagation of human focal seizures. Neuroimage. 2015 Nov 15; 122:114-30. View abstract
  51. Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy. Epilepsy Res. 2015 Sep; 115:113-8. View abstract
  52. Central 5-HT neurotransmission modulates weight loss following gastric bypass surgery in obese individuals. J Neurosci. 2015 Apr 08; 35(14):5884-9. View abstract
  53. Laminar profile of spontaneous and evoked theta: Rhythmic modulation of cortical processing during word integration. Neuropsychologia. 2015 Sep; 76:108-24. View abstract
  54. Decrease in gamma-band activity tracks sequence learning. Front Syst Neurosci. 2014; 8:222. View abstract
  55. Lexical retrieval pre- and posttemporal lobe epilepsy surgery in a pediatric sample. Epilepsy Behav. 2015 Jan; 42:61-5. View abstract
  56. Sensitivity to timing and order in human visual cortex. J Neurophysiol. 2015 Mar 01; 113(5):1656-69. View abstract
  57. Passive fMRI mapping of language function for pediatric epilepsy surgical planning: validation using Wada, ECS, and FMAER. Epilepsy Res. 2014 Dec; 108(10):1874-88. View abstract
  58. VEGF: a potential target for hydrocephalus. Cell Tissue Res. 2014 Dec; 358(3):667-83. View abstract
  59. 183 Intracranial arachnoid cysts and hemorrhage. Neurosurgery. 2014 Aug; 61 Suppl 1:220. View abstract
  60. Neuronal ensemble synchrony during human focal seizures. J Neurosci. 2014 Jul 23; 34(30):9927-44. View abstract
  61. Spatiotemporal dynamics underlying object completion in human ventral visual cortex. Neuron. 2014 Aug 06; 83(3):736-48. View abstract
  62. Comparison of rapid cranial MRI to CT for ventricular shunt malfunction. Pediatrics. 2014 Jul; 134(1):e47-54. View abstract
  63. 3 Tesla intraoperative MRI for brain tumor surgery. J Magn Reson Imaging. 2014 Jun; 39(6):1357-65. View abstract
  64. Surgery for intractable epilepsy due to unilateral brain disease: a retrospective study comparing hemispherectomy techniques. Pediatr Neurol. 2014 Sep; 51(3):336-43. View abstract
  65. Rasmussen's encephalitis presenting as focal cortical dysplasia. Epilepsy Behav Case Rep. 2014; 2:86-9. View abstract
  66. Neural dynamics underlying target detection in the human brain. J Neurosci. 2014 Feb 19; 34(8):3042-55. View abstract
  67. Clinical value of magnetoencephalographic spike propagation represented by spatiotemporal source analysis: correlation with surgical outcome. Epilepsy Res. 2014 Feb; 108(2):280-8. View abstract
  68. Outcomes of vagal nerve stimulation in a pediatric population: a single center experience. Seizure. 2014 Feb; 23(2):105-11. View abstract
  69. Resection of supratentorial lobar cavernous malformations in children: clinical article.. J Neurosurg Pediatr. 2013 Oct; 12(4):367-73. View abstract
  70. Electrode localization for planning surgical resection of the epileptogenic zone in pediatric epilepsy. Int J Comput Assist Radiol Surg. 2014 Jan; 9(1):91-105. View abstract
  71. Perfusion Imaging of Focal Cortical Dysplasia Using Arterial Spin Labeling: Correlation With Histopathological Vascular Density. J Child Neurol. 2013 Nov; 28(11):1474-1482. View abstract
  72. Moyamoya disease with mesial temporal sclerosis. J Neurosurg Pediatr. 2013 Jun; 11(6):713-6. View abstract
  73. First result from the Alpha Magnetic Spectrometer on the International Space Station: precision measurement of the positron fraction in primary cosmic rays of 0.5-350 GeV. Phys Rev Lett. 2013 Apr 05; 110(14):141102. View abstract
  74. VEGF, which is elevated in the CSF of patients with hydrocephalus, causes ventriculomegaly and ependymal changes in rats. Exp Neurol. 2013 Sep; 247:703-9. View abstract
  75. The frequency modulated auditory evoked response (FMAER), a technical advance for study of childhood language disorders: cortical source localization and selected case studies. BMC Neurol. 2013 Jan 25; 13:12. View abstract
  76. The postnatal human filum terminale is a source of autologous multipotent neurospheres capable of generating motor neurons. Neurosurgery. 2013 Jan; 72(1):118-29; discussion 129. View abstract
  77. Detecting epileptic regions based on global brain connectivity patterns. Med Image Comput Comput Assist Interv. 2013; 16(Pt 1):98-105. View abstract
  78. Human seizures self-terminate across spatial scales via a critical transition. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):21116-21. View abstract
  79. Postshunting corpus callosum swelling with depiction on tractography. J Neurosurg Pediatr. 2013 Feb; 11(2):178-80. View abstract
  80. Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness. Proc Natl Acad Sci U S A. 2012 Dec 04; 109(49):E3377-86. View abstract
  81. Impaired pulsation absorber mechanism in idiopathic normal pressure hydrocephalus: laboratory investigation. J Neurosurg. 2012 Dec; 117(6):1189-96. View abstract
  82. Temporal stability of visually selective responses in intracranial field potentials recorded from human occipital and temporal lobes. J Neurophysiol. 2012 Dec; 108(11):3073-86. View abstract
  83. Language lateralization represented by spatiotemporal mapping of magnetoencephalography. AJNR Am J Neuroradiol. 2013 Mar; 34(3):558-63. View abstract
  84. Predictors of ventricular shunt infection among children presenting to a pediatric emergency department. Pediatr Emerg Care. 2012 May; 28(5):405-9. View abstract
  85. Autonomic changes with seizures correlate with postictal EEG suppression. Neurology. 2012 Jun 05; 78(23):1868-76. View abstract
  86. Altered inhibition in tuberous sclerosis and type IIb cortical dysplasia. Ann Neurol. 2012 Apr; 71(4):539-51. View abstract
  87. Convulsive seizure detection using a wrist-worn electrodermal activity and accelerometry biosensor. Epilepsia. 2012 May; 53(5):e93-7. View abstract
  88. Spatiotemporal dynamics of neocortical excitation and inhibition during human sleep. Proc Natl Acad Sci U S A. 2012 Jan 31; 109(5):1731-6. View abstract
  89. Robotic Neuro-Endoscope with Concentric Tube Augmentation. Rep U S. 2012. View abstract
  90. Individualized localization and cortical surface-based registration of intracranial electrodes. Neuroimage. 2012 Feb 15; 59(4):3563-70. View abstract
  91. Multimodal imaging of spike propagation: a technical case report. AJNR Am J Neuroradiol. 2012 Jun; 33(6):E82-4. View abstract
  92. Widespread Brain Areas Engaged during a Classical Auditory Streaming Task Revealed by Intracranial EEG. Front Hum Neurosci. 2011; 5:74. View abstract
  93. Nasal glioma: prenatal diagnosis and multidisciplinary surgical approach. Skull Base Rep. 2011 Nov; 1(2):83-8. View abstract
  94. Algorithms for Design of Continuum Robots Using the Concentric Tubes Approach: A Neurosurgical Example. IEEE Int Conf Robot Autom. 2011 May 09; 667-673. View abstract
  95. Single-neuron dynamics in human focal epilepsy. Nat Neurosci. 2011 May; 14(5):635-41. View abstract
  96. Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging. J Neurosurg. 2011 Jun; 114(6):1693-7. View abstract
  97. The pulsating brain: A review of experimental and clinical studies of intracranial pulsatility. Fluids Barriers CNS. 2011 Jan 18; 8(1):5. View abstract
  98. Evaluation of the ShuntCheck noninvasive thermal technique for shunt flow detection in hydrocephalic patients. Neurosurgery. 2011 Jan; 68(1):198-205; discussion 205. View abstract
  99. Idiopathic syrinx in the pediatric population: a combined center experience. J Neurosurg Pediatr. 2011 Jan; 7(1):30-6. View abstract
  100. Modeling of blood flow in arterial trees. Wiley Interdiscip Rev Syst Biol Med. 2010 Sep-Oct; 2(5):612-623. View abstract
  101. Alterations of pulsation absorber characteristics in experimental hydrocephalus. J Neurosurg Pediatr. 2010 Aug; 6(2):159-70. View abstract
  102. Modeling blood flow circulation in intracranial arterial networks: a comparative 3D/1D simulation study. Ann Biomed Eng. 2011 Jan; 39(1):297-309. View abstract
  103. Heterogeneous neuronal firing patterns during interictal epileptiform discharges in the human cortex. Brain. 2010 Jun; 133(Pt 6):1668-81. View abstract
  104. Current dipole orientation and distribution of epileptiform activity correlates with cortical thinning in left mesiotemporal epilepsy. Neuroimage. 2010 Oct 01; 52(4):1238-42. View abstract
  105. Right-lateralized brain oscillations in human spatial navigation. J Cogn Neurosci. 2010 May; 22(5):824-36. View abstract
  106. Robust selectivity to two-object images in human visual cortex. Curr Biol. 2010 May 11; 20(9):872-9. View abstract
  107. A dynamic nonlinear relationship between the static and pulsatile components of intracranial pressure in patients with subarachnoid hemorrhage. J Neurosurg. 2010 Mar; 112(3):616-25. View abstract
  108. Arterial blood pressure vs intracranial pressure in normal pressure hydrocephalus. Acta Neurol Scand. 2010 Oct; 122(4):262-9. View abstract
  109. Continuous monitoring of electrodermal activity during epileptic seizures using a wearable sensor. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:4415-8. View abstract
  110. Propagation of epileptic spikes reconstructed from spatiotemporal magnetoencephalographic and electroencephalographic source analysis. Neuroimage. 2010 Mar; 50(1):217-22. View abstract
  111. Magnetoencephalographic analysis in patients with vagus nerve stimulator. Pediatr Neurol. 2009 Nov; 41(5):383-7. View abstract
  112. Task-free presurgical mapping using functional magnetic resonance imaging intrinsic activity. J Neurosurg. 2009 Oct; 111(4):746-54. View abstract
  113. Estimation of Eeg Signal Dispersion During Seizure Propagation. Int Conf Digit Signal Process Proc. 2009 Sep 18; 2009:1-5. View abstract
  114. Urological outcome following multiple repeat spinal cord untethering operations. Clinical article. J Neurosurg Pediatr. 2009 Sep; 4(3):275-9. View abstract
  115. Gender and the use of hormonal contraception in women are not associated with cerebral cortical 5-HT 2A receptor binding. Neuroscience. 2009 Oct 06; 163(2):640-5. View abstract
  116. Simulation of the human intracranial arterial tree. Philos Trans A Math Phys Eng Sci. 2009 Jun 13; 367(1896):2371-86. View abstract
  117. The human K-complex represents an isolated cortical down-state. Science. 2009 May 22; 324(5930):1084-7. View abstract
  118. Timing, timing, timing: fast decoding of object information from intracranial field potentials in human visual cortex. Neuron. 2009 Apr 30; 62(2):281-90. View abstract
  119. Dynamic statistical parametric mapping for analyzing ictal magnetoencephalographic spikes in patients with intractable frontal lobe epilepsy. Epilepsy Res. 2009 Aug; 85(2-3):279-86. View abstract
  120. Brain serotonin 2A receptor binding: relations to body mass index, tobacco and alcohol use. Neuroimage. 2009 May 15; 46(1):23-30. View abstract
  121. Task-free presurgical mapping using fMRI intrinsic activity. J Neurosurgery,in press. 2009. View abstract
  122. Large-scale simulation of the human arterial tree. Clin Exp Pharmacol Physiol. 2009 Feb; 36(2):194-205. View abstract
  123. Intracranial pressure waves: characterization of a pulsation absorber with notch filter properties using systems analysis: laboratory investigation. J Neurosurg Pediatr. 2008 Jul; 2(1):83-94. View abstract
  124. Identification of endogenous morphine and a mu3-like opiate alkaloid receptor in human brain tissue taken from a patient with intractable complex partial epilepsy. Med Sci Monit. 2008 Jun; 14(6):CS45-49. View abstract
  125. Nonresective Surgical Management of Refractory Epilepsy: Callosotomy and Vagal Stimulation. Principles and Practice of Pediatric Neurosurgery. 2008. View abstract
  126. Gamma oscillations distinguish true from false memories. Psychol Sci. 2007 Nov; 18(11):927-32. View abstract
  127. Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshop. J Neurosurg. 2007 Nov; 107(5 Suppl):345-57. View abstract
  128. Minimal heating of titanium skull plates during 1Hz repetitive transcranial magnetic stimulation. Clin Neurophysiol. 2007 Nov; 118(11):2536-8. View abstract
  129. Apparatus and method for measuring a human head. 2007. View abstract
  130. Outcome following multiple repeated spinal cord untethering operations. J Neurosurg. 2007 Jun; 106(6 Suppl):434-8. View abstract
  131. Treatment of subdural hematomas in infants. J Neurosurg. 2007 Mar; 106(3 Suppl):171. View abstract
  132. The emerging field of third circulation research. Clin Neurosurg. 2007; 54:129-33. View abstract
  133. MRI and Physiologically Guided Brain Tumor Removal (Live Webcast, ORLive). 2006. View abstract
  134. Hippocampal and neocortical gamma oscillations predict memory formation in humans. Cereb Cortex. 2007 May; 17(5):1190-6. View abstract
  135. Electroencephalography in epilepsy surgery planning. Childs Nerv Syst. 2006 Aug; 22(8):760-5. View abstract
  136. Human neocortical oscillations exhibit theta phase differences between encoding and retrieval. Neuroimage. 2006 Jul 01; 31(3):1352-8. View abstract
  137. The value of multichannel MEG and EEG in the presurgical evaluation of 70 epilepsy patients. Epilepsy Res. 2006 Apr; 69(1):80-6. View abstract
  138. What we don't (but should) know about hydrocephalus. J Neurosurg. 2006 Mar; 104(3 Suppl):157-9. View abstract
  139. Cerebrospinal fluid pulsatility and hydrocephalus: the fourth circulation. Clin Neurosurg. 2006; 53:48-52. View abstract
  140. Treatment of refractory epilepsy: General approach and nonresective strategies. Albright L et al, eds., Pediatric Neurosurgery. 2006. View abstract
  141. Theta oscillations in human cortex during a working-memory task: evidence for local generators. J Neurophysiol. 2006 Mar; 95(3):1630-8. View abstract
  142. GMFM 1 year after continuous intrathecal baclofen infusion. Pediatr Rehabil. 2005 Jul-Sep; 8(3):207-13. View abstract
  143. Invasive group A, B, C and G streptococcal infections in Denmark 1999-2002: epidemiological and clinical aspects. Clin Microbiol Infect. 2005 Jul; 11(7):569-76. View abstract
  144. Ictal asystole with convulsive syncope mimicking secondary generalisation: a depth electrode study. J Neurol Neurosurg Psychiatry. 2005 Jun; 76(6):885-7. View abstract
  145. Increased Phase Synchronization between Intracranial Pressure and Arterial Blood Pressure during Elevated Intracranial Pressure in Dogs. Conf Proc IEEE Eng Med Biol Soc. 2005; 2006:315-8. View abstract
  146. Direction-oriented and spatially controlled bipolar for in-situ cauterization of adherent cranial tissue occluding a ventricular catheter previously implanted in-vivo. 2004. View abstract
  147. Gamma EEG dynamics in neocortex and hippocampus during human wakefulness and sleep. Neuroimage. 2004 Jul; 22(3):1271-80. View abstract
  148. Neurosurgical aspects of critical care neurology. Semin Pediatr Neurol. 2004 Jun; 11(2):169-78. View abstract
  149. Cerebral pathophysiology and critical care neurology: basic hemodynamic principles, cerebral perfusion, and intracranial pressure. Semin Pediatr Neurol. 2004 Jun; 11(2):89-104. View abstract
  150. Antenatal neurosurgical counseling: approach to the unborn patient. Pediatr Clin North Am. 2004 Apr; 51(2):491-505. View abstract
  151. Hip status in cerebral palsy after one year of continuous intrathecal baclofen infusion. Pediatr Neurol. 2004 Mar; 30(3):163-8. View abstract
  152. Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosis. J Neurosurg. 2004 Feb; 100(2 Suppl Pediatrics):142-9. View abstract
  153. Laminar analysis of human neocortical interictal spike generation and propagation: current source density and multiunit analysis in vivo. Epilepsia. 2004; 45 Suppl 4:48-56. View abstract
  154. Antenatal Neurosurgical counseling: Approach to the unborn patient. Pedi Clin N Amer. 2004; 51:491-505. View abstract
  155. Treatment of epilepsy by vagal nerve stimulation. Schmidek H, ed., Operative Neurosurgery (in press). 2004. View abstract
  156. Gamma oscillations correlate with working memory load in humans. Cereb Cortex. 2003 Dec; 13(12):1369-74. View abstract
  157. Theta and gamma oscillations during encoding predict subsequent recall. J Neurosci. 2003 Nov 26; 23(34):10809-14. View abstract
  158. Sleep-dependent theta oscillations in the human hippocampus and neocortex. J Neurosci. 2003 Nov 26; 23(34):10897-903. View abstract
  159. Reset of human neocortical oscillations during a working memory task. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7931-6. View abstract
  160. Human theta oscillations related to sensorimotor integration and spatial learning. J Neurosci. 2003 Jun 01; 23(11):4726-36. View abstract
  161. Pharyngeal dysesthesia in refractory complex partial epilepsy: new seizure or adverse effect of vagal nerve stimulation? Epilepsia. 2003 Jun; 44(6):855-8. View abstract
  162. Non-invasive in vivo pressure measurement. 2003. View abstract
  163. Shunt technology: contemporary concepts and prospects. Clin Neurosurg. 2003; 50:256-67. View abstract
  164. Carotid and vertebral artery dissections in children and adults. Batjer HH, Loftus CM, eds. Textbook of Neurological Surgery: Principles and Practice. 2003; 1:1121-1127. View abstract
  165. Neonatal hydrocephalus. Hansen AR, Puder M, eds., Manual of Neonatal Surgical Intensive Care. 2003; 381-393. View abstract
  166. Shunt technology: Contemporary concepts and prospects. Contemporary Neurosurgery. 2003. View abstract
  167. Neurosurgery of the Newborn. Avery GB, Fletcher MA, McDonald MG, eds., Neonatology: Pathophysiology and Management of the Newborn (in press). 2003. View abstract
  168. Syringomyelia. Adelman G, Smith BH, eds., Encylcopedia of Neuroscience (in press). 2003. View abstract
  169. Syringomyelia. Aminoff M, Daroff R, eds., Encyclopedia of Neurological Sciences. 2003; 4:465-469. View abstract
  170. Gamma oscillations increase with working memory load in humans. Cerebral Cortex. 2003; 13(12):1369-74. View abstract
  171. Neonatal hydrocephalus. Hansen AR, Puder M, eds., Manual of Neonatal Surgical Intensive Care. 2003; 394-405. View abstract
  172. Surgical treatment of pain in the child. Schechter NL, Berde CB, Yaster M, eds., Pain Management in Infants, Children and Adolescents. 2003; 329-339. View abstract
  173. Biochemical characterization of pediatric brain tumors by using in vivo and ex vivo magnetic resonance spectroscopy. J Neurosurg. 2002 Jun; 96(6):1023-31. View abstract
  174. Variable anti-siphon valve apparatus and method. 2002. View abstract
  175. Neurotrauma. Fleisher GR, Ludwig S, eds., Synopsis of Pediatric Emergency Medicine, Revised Edition. 2002; 474-486. View abstract
  176. Congenital malformations of the cerebellum and posterior fossa. Manto M-U, Pandolfo M, eds, The Cerebellum and Its Disorders. 2002; 161-177. View abstract
  177. Theta returns. Curr Opin Neurobiol. 2001 Dec; 11(6):739-44. View abstract
  178. Vagus nerve stimulation in pediatric epilepsy: a review. Pediatr Neurol. 2001 Nov; 25(5):368-76. View abstract
  179. Vagus nerve stimulation therapy in pediatric patients with refractory epilepsy: retrospective study. J Child Neurol. 2001 Nov; 16(11):843-8. View abstract
  180. Non-invasive in vivo pressure measurement. 2001. View abstract
  181. Gentle dorsal root retraction and dissection can cause areflexia: implications for intraoperative monitoring during "selective" partial dorsal rhizotomy. Muscle Nerve. 2001 Oct; 24(10):1352-8. View abstract
  182. Temporal lobectomy in early childhood: the need for long-term follow-up. J Child Neurol. 2001 Aug; 16(8):585-90. View abstract
  183. Distinct patterns of brain oscillations underlie two basic parameters of human maze learning. J Neurophysiol. 2001 Jul; 86(1):368-80. View abstract
  184. Gating of human theta oscillations by a working memory task. J Neurosci. 2001 May 01; 21(9):3175-83. View abstract
  185. Shunt Malfunction. In: Gilman S ed. Medlink Neurology. (electronic media). 2001. View abstract
  186. Corpus callosotomy. Albright AL, Pollack IF, Adelson PD, eds., Atlas of Operative Techniques in Pediatric Neurosurgery. 2001; 257-265. View abstract
  187. Prenatal diagnosis and counseling for the neurosurgeon. McLone DG, ed., Pediatric Neurosurgery. 2001; 332-341. View abstract
  188. Vagus nerve stimulation in pediatric epilepsy: A review. Pediatric Neurol. 2001; 25:368-76. View abstract
  189. Long-term vagus nerve stimulation beneficial in refractory epilepsy. Journal Watch Neurology. 2000; 2:3. View abstract
  190. 834 Event Related Potentials (ERPs) for Memory: Toward Localization of Cognitive Functions in Children. Neurosurgery. 2000 Aug 01; 47(2):538. View abstract
  191. Subdural electrode arrays for monitoring cortical electrical activity. 2000. View abstract
  192. Non-invasive in vivo pressure measurement. 2000. View abstract
  193. [Chronic inflammatory bowel disease--pathogenic concepts and therapeutic perspectives]. Ugeskr Laeger. 2000 Mar 06; 162(10):1361-6. View abstract
  194. Intrathecal baclofen for management of spastic cerebral palsy: multicenter trial. J Child Neurol. 2000 Feb; 15(2):71-7. View abstract
  195. The living shunt: a tissue engineering approach in the treatment of hydrocephalus. Neurol Res. 2000 Jan; 22(1):105-10. View abstract
  196. The effect of propofol on intraoperative electrocorticography and cortical stimulation during awake craniotomies in children. Paediatr Anaesth. 2000; 10(1):29-34. View abstract
  197. Pathophysiology, prevention, and potential treatment of neural tube defects. Ment Retard Dev Disabil Res Rev. 2000; 6(1):6-14. View abstract
  198. Pathology, Prevention, and Potential Treatment of Neural Tube Defects. Mental Retardation and Develop Disabil Res Rev. 2000; 6:6-14. View abstract
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  293. Treatment of medulloblastoma with pre-irradiation chemotherapy: experience at Boston Children’s Hospital from 1984 to 1991 - Pediatric Session. 1993. View abstract
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