Dr. Alan Leichtner's research focuses on developing and evaluating treatments for inflammatory bowel disease, gastroesophageal reflux, and celiac disease in children.


Dr. Alan Leichtner is a graduate of Harvard Medical School. He completed an internship, residency and fellowship at Boston Children's Hospital.


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  1. Non-responsive celiac disease in children on a gluten free diet. World J Gastroenterol. 2021 Apr 07; 27(13):1311-1320. View abstract
  2. North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on Entrustable Professional Activities: Development of Pediatric Gastroenterology, Hepatology, and Nutrition Entrustable Professional Activities. J Pediatr Gastroenterol Nutr. 2020 07; 71(1):136-143. View abstract
  3. Pediatric Gastroenterology, Hepatology, and Nutrition Entrustable Professional Activities: Development of an Assessment Tool and Curricular Resources. J Pediatr Gastroenterol Nutr. 2020 07; 71(1):e40-e45. View abstract
  4. Visiting Jack: Mixed Methods Evaluation of a Virtual Home Visit Curriculum With a Child With Medical Complexity. Acad Pediatr. 2020 Sep - Oct; 20(7):1020-1028. View abstract
  5. Use of Nazi torture device image in digital scholarship article. Med Teach. 2020 06; 42(6):717-718. View abstract
  6. Training in Endoscopy: Coaching, Deliberate Practice, and Reflection. J Pediatr Gastroenterol Nutr. 2019 03; 68(3):298-300. View abstract
  7. Interprofessional provider educational needs and preferences regarding the provision of sexual and reproductive health care in cystic fibrosis. J Cyst Fibros. 2019 09; 18(5):671-676. View abstract
  8. Red Spot Lesions in the Duodenal Bulb Are a Highly Specific Endoscopic Sign of Celiac Disease: A Prospective Study. J Pediatr Gastroenterol Nutr. 2019 02; 68(2):251-255. View abstract
  9. Lack of Follow-up of Pediatric Patients With Celiac Disease. Clin Gastroenterol Hepatol. 2019 11; 17(12):2603-2604. View abstract
  10. Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects. J Allergy Clin Immunol. 2018 12; 142(6):1932-1946. View abstract
  11. Objective Assessment of Fellows: Doable and Worth Doing. J Pediatr Gastroenterol Nutr. 2017 04; 64(4):498-500. View abstract
  12. Value of IgA tTG in Predicting Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017 02; 64(2):286-291. View abstract
  13. The Boston Children's Hospital Academy: Development and Initial Assessment of a Hospital-Based Teaching Academy. Acad Med. 2016 12; 91(12):1651-1654. View abstract
  14. 'Constipation Challenge' game improves guideline knowledge and implementation. Med Educ. 2016 May; 50(5):589-90. View abstract
  15. Shared care: a quality improvement initiative to optimize primary care management of constipation. Pediatrics. 2015 May; 135(5):e1300-7. View abstract
  16. Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4. Gut. 2015 Dec; 64(12):1889-97. View abstract
  17. Assessment tools: the next frontier in competency-based medical education. J Pediatr Gastroenterol Nutr. 2014 Oct; 59(4):425-7. View abstract
  18. Graduate medical education in humanism and professionalism: a needs assessment survey of pediatric gastroenterology fellows. J Pediatr Gastroenterol Nutr. 2014 Jan; 58(1):34-7. View abstract
  19. NASPGHAN guidelines for training in pediatric gastroenterology. J Pediatr Gastroenterol Nutr. 2013 Jan; 56 Suppl 1:S1-8. View abstract
  20. Navigating the gluten-free diet in college. J Pediatr Gastroenterol Nutr. 2012 Dec; 55(6):740-4. View abstract
  21. Multicenter study on season of birth and celiac disease: evidence for a new theoretical model of pathogenesis. J Pediatr. 2013 Mar; 162(3):501-4. View abstract
  22. Pediatric gastroenterology fellowship: is the match working? J Pediatr Gastroenterol Nutr. 2010 Aug; 51(2):243-4. View abstract
  23. Variability of histopathological changes in childhood celiac disease. Am J Gastroenterol. 2010 Jan; 105(1):207-12. View abstract
  24. Restorative proctocolectomy and ileal pouch-anal anastomosis in children. Dis Colon Rectum. 2009 Sep; 52(9):1645-9. View abstract
  25. First evidence of a possible association between gastric acid suppression during pregnancy and childhood asthma: a population-based register study. Clin Exp Allergy. 2009 Feb; 39(2):246-53. View abstract
  26. Desquamative enteropathy and pyloric atresia without skin disease caused by a novel intracellular beta4 integrin mutation. J Pediatr Gastroenterol Nutr. 2008 Nov; 47(5):585-91. View abstract
  27. Clinical significance of colonic intraepithelial lymphocytosis in a pediatric population. Mod Pathol. 2009 Jan; 22(1):13-20. View abstract
  28. Fellowship training in pediatric gastroenterology in the United States: where are we going? Does one size fit all? J Pediatr Gastroenterol Nutr. 2008 Sep; 47(3):274-6. View abstract
  29. Clinical effects and safety of rituximab for treatment of refractory pediatric autoimmune diseases. J Pediatr. 2007 Apr; 150(4):376-82. View abstract
  30. Celiac disease presenting with chilblains in an adolescent girl. Pediatr Dermatol. 2006 Sep-Oct; 23(5):451-4. View abstract
  31. Serologic testing with ANCA, ASCA, and anti-OmpC in children and young adults with Crohn's disease and ulcerative colitis: diagnostic value and correlation with disease phenotype. Am J Gastroenterol. 2004 Nov; 99(11):2235-41. View abstract
  32. Depressive symptoms and inflammatory bowel disease in children and adolescents: a cross-sectional study. J Pediatr Gastroenterol Nutr. 2004 Oct; 39(4):395-403. View abstract
  33. Pediatric patients with untreated ulcerative colitis may present initially with unusual morphologic findings. Am J Surg Pathol. 2004 Feb; 28(2):190-7. View abstract
  34. Retrospective study of hepatic enzyme elevations in children treated with olanzapine, divalproex, and their combination. J Am Acad Child Adolesc Psychiatry. 2003 Oct; 42(10):1227-33. View abstract
  35. Complementary medicine use in children and young adults with inflammatory bowel disease. Am J Gastroenterol. 2002 Feb; 97(2):382-8. View abstract
  36. Elevated serum hepatocyte growth factor in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2001 Nov; 33(5):548-53. View abstract
  37. Oral tacrolimus treatment of severe colitis in children. J Pediatr. 2000 Dec; 137(6):794-9. View abstract
  38. Allergic esophagitis in children: a clinicopathological entity. Am J Surg Pathol. 1999 Apr; 23(4):390-6. View abstract
  39. Human intestinal M cells display the sialyl Lewis A antigen. Infect Immun. 1999 Feb; 67(2):946-53. View abstract
  40. Elevated serum vascular endothelial growth factor in children and young adults with Crohn's disease. Dig Dis Sci. 1999 Feb; 44(2):424-30. View abstract
  41. Quality-of-life assessment after ileoanal pull-through for ulcerative colitis and familial adenomatous polyposis. J Pediatr Surg. 1999 Jan; 34(1):163-6. View abstract
  42. Aluminum in large and small volume parenterals used in total parenteral nutrition: response to the Food and Drug Administration notice of proposed rule by the North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr. 1998 Oct; 27(4):457-60. View abstract
  43. Gastrointestinal manifestations of vascular anomalies in childhood: varied etiologies require multiple therapeutic modalities. J Pediatr Surg. 1998 Jul; 33(7):1163-7. View abstract
  44. Serum leptin in children and young adults with inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 1998 May; 26(5):500-5. View abstract
  45. Vitamins A and E serum levels in children and young adults with inflammatory bowel disease: effect of disease activity. J Pediatr Gastroenterol Nutr. 1998 Feb; 26(2):129-35. View abstract
  46. Clinical outcome of ulcerative proctitis in children. J Pediatr Gastroenterol Nutr. 1997 Aug; 25(2):149-52. View abstract
  47. Surgery for Crohn's disease in infants and children. J Pediatr Surg. 1997 Jul; 32(7):1063-7; discussion 1067-8. View abstract
  48. Serum basic fibroblast growth factor in pediatric Crohn's disease. Implications for wound healing. Dig Dis Sci. 1997 Feb; 42(2):378-86. View abstract
  49. Complications following percutaneous endoscopic gastrostomy and subsequent catheter replacement in children and young adults. Gastrointest Endosc. 1997 Jan; 45(1):64-71. View abstract
  50. Tacrolimus (FK-506) treatment of fulminant colitis in a child. J Pediatr Gastroenterol Nutr. 1996 Oct; 23(3):329-33. View abstract
  51. Elevation of serum interleukin-6 but not serum-soluble interleukin-2 receptor in children with Crohn's disease. J Pediatr Gastroenterol Nutr. 1996 Aug; 23(2):164-71. View abstract
  52. Treatment of pediatric autoimmune enteropathy with tacrolimus (FK506). Gastroenterology. 1996 Jul; 111(1):237-43. View abstract
  53. Gastric and esophageal intraepithelial lymphocytes in pediatric celiac disease. Am J Surg Pathol. 1996 Jul; 20(7):865-70. View abstract
  54. Long-term hepatic regeneration and function in infants and children following liver resection. J Am Coll Surg. 1996 Jun; 182(6):515-9. View abstract
  55. Intraoperative enteroscopy in the diagnosis of partial intestinal obstruction in infancy. Dig Dis Sci. 1995 Oct; 40(10):2236-8. View abstract
  56. Aminosalicylates for the treatment of inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 1995 Oct; 21(3):245-52. View abstract
  57. Allergic colitis in infants. J Pediatr. 1995 Feb; 126(2):163-70. View abstract
  58. Endoscopic ligation of esophageal varices in children. J Pediatr Gastroenterol Nutr. 1995 Feb; 20(2):202-8. View abstract
  59. Medical therapies for pediatric gastrointestinal disease. Subcommittee on Therapeutics of the Patient Care Committee North American Society for Pediatric Gastroenterology and Nutrition. J Pediatr Gastroenterol Nutr. 1994 Apr; 18(3):269. View abstract
  60. Long-term nutritional and metabolic consequences of pancreaticoduodenectomy in children. Surgery. 1994 Mar; 115(3):382-8. View abstract
  61. Allergic proctocolitis in infants: a prospective clinicopathologic biopsy study. Hum Pathol. 1993 Jun; 24(6):668-74. View abstract
  62. The antegrade colonogram: extending the small bowel follow through for children suspected of having colonic disease. Pediatr Radiol. 1992; 22(8):573-6. View abstract
  63. Pancreatitis following scoliosis surgery in children and young adults. J Pediatr Orthop. 1991 Sep-Oct; 11(5):594-8. View abstract
  64. Longitudinal assessment of type I procollagen in children with inflammatory bowel disease subjected to surgery. J Pediatr Gastroenterol Nutr. 1989 Jan; 8(1):68-74. View abstract
  65. Carbohydrate malabsorption following fruit juice ingestion in young children. Pediatrics. 1988 Jul; 82(1):64-8. View abstract
  66. Relationship of type I procollagen to corticosteroid therapy in children with inflammatory bowel disease. J Pediatr. 1988 Jun; 112(6):893-8. View abstract
  67. Clinical and laboratory correlates of esophagitis in young children. J Pediatr Gastroenterol Nutr. 1988 Jan-Feb; 7(1):52-6. View abstract
  68. Hypertension associated with unilateral hydronephrosis as a complication of Crohn's disease. J Pediatr Surg. 1987 Nov; 22(11):1049-50. View abstract
  69. Cyclosporine treatment of autoimmune chronic active hepatitis. Gastroenterology. 1987 Oct; 93(4):890-3. View abstract
  70. Type 1 procollagen as a biochemical marker of growth in children with inflammatory bowel disease. J Pediatr. 1986 Oct; 109(4):619-24. View abstract
  71. Effect of metoclopramide on prolonged intraesophageal pH testing in infants with gastroesophageal reflux. J Pediatr Gastroenterol Nutr. 1986 Sep-Oct; 5(5):716-20. View abstract
  72. Chronic diarrhea associated with hypogammaglobulinemia and enteropathy in infants and children. Dig Dis Sci. 1985 Dec; 30(12):1149-55. View abstract
  73. Cerebral vascular accident during the recovery phase of hemolytic uremic syndrome. Int J Pediatr Nephrol. 1985 Oct-Dec; 6(4):287-8. View abstract
  74. Discordance for biliary atresia in two sets of monozygotic twins. J Pediatr. 1985 Sep; 107(3):420-2. View abstract
  75. Apple juice. An unappreciated cause of chronic diarrhea. Am J Dis Child. 1985 May; 139(5):503-5. View abstract
  76. Pseudopheochromocytoma and cardiac arrest associated with phenylpropanolamine. JAMA. 1985 Mar 15; 253(11):1609-10. View abstract
  77. Recent advances in diagnosis and treatment of gastrointestinal hemorrhage in infants and children. J Pediatr. 1985 Jan; 106(1):1-9. View abstract
  78. Regulation of low density lipoprotein receptor function in a human hepatoma cell line. Hepatology. 1984 Sep-Oct; 4(5):897-901. View abstract
  79. Addition of a mannose-6-phosphate-containing oligosaccharide alters cellular processing of low density lipoprotein by parental and LDL-receptor-defective Chinese hamster ovary cells. J Cell Sci. 1984 Jun; 68:183-94. View abstract
  80. Horizontal nonparenteral spread of hepatitis B among children. Ann Intern Med. 1981 Mar; 94(3):346-9. View abstract