Researcher | Research Background
Dr. Dheeraj Soni is a molecular biologist, specifically interested in delineating mechanistic pathways regulating immune function. He earned a BS in Biotechnology degree from North Dakota State University and a Ph.D. in Cellular and Molecular Pharmacology from the University of Illinois at Chicago (in 2017). For his predoctoral research, Dheeraj focused on TLR4- and GPCR-induced pathways regulating endothelial barrier function. Utilizing novel peptides, tissue-specific knockout mouse models and in vivo gene deletion using CRISPR, he co-authored several high-impact journal publications. Working closely with Dr. Dowling, Dheeraj is involved with multiple aspects of adjuvant related projects. These projects are NIH-funded contracts, aimed at discovering novel adjuvants and developing formulations to enhance immunization against influenza and pertussis, in age-specific context. Dheeraj is particularly interested in receptor identification and studying cell-specific response of these adjuvants. As a part of the Precision Vaccines Program, the outcomes of his research work are aimed at guiding adjuvanted-vaccine development.