Dr. Chen's research concerns the molecular mechanisms of HIV (human immunodeficiency virus) entry -- how HIV enters host cells and how the viral envelope protein interacts with host cellular receptors. The goal is to obtain a structurally accurate “molecular movie” of viral entry and to establish an in vitro system to recapitulate the viral membrane fusion process for mechanistic investigations at the molecular level. Insights gained from these studies will lead to a much deeper understanding of the mechanisms of viral entry and antibody neutralization and will also guide development of vaccines and therapeutics against HIV infection.


Dr. Chen received his PhD from Ohio State University and received his postgraduate training at Children's Hospital Boston and Harvard Medical School.