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Intestinal Diseases | Overview

David Breault, MD, PhD, of the Boston Children’s Hospital Division of Endocrinology and an affiliate member of the Stem Cell Program, studies the small intestine’s stem cells, which are found in the wall of the intestine in small crypts.

These highly-specialized cells are resistant to typical injuries affecting the gut and are thought to help in the healing process. Breault and his team are particularly interested in telomerase, an enzyme that allows unlimited division of stem cells. Understanding how these important cells are regulated may one day lead to treatments for intestinal diseases.