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Thiagarajah Lab Research | Overview

Research in the lab aims to understand how cells sense and interacts with their surroundings and how membrane channels and transporters contribute to immune function, host-microbial symbiosis, and cellular metabolism. Research projects in the lab use a variety of approaches and span several aspects of physiology and disease, including both basic science and translational research. Our lab uses high resolution quantitative imaging, electrophysiology, patient derived organoids, and mouse genetic models to investigate how the intestinal epithelium responds to the surrounding environment. An important aspect of our research also involves development of novel optical methods and tools for studying tissue and cell biology.