Current Environment:

Staff

Postdoctoral Fellows

Camille Le Gall, PhD Camille Le Gall, PhD | Email
PhD in immunology, Radboud University Nijmegen, The Netherlands

My general interest lies in the development of nanobody-based therapeutics to modulate immune responses. In my current work, I am applying such tools to improve immunity to infectious diseases, specifically malaria. When not in the lab, you can usually find me hiking or exercising outdoors!

Thomas Balligand, MD, PhD Thomas Balligand, MD, PhD | Email
MD Université Catholique de Louvain, Belgium
PhD in Biomedical and Pharmaceutical Sciences, Université Catholique de Louvain, Belgium

I am interested in developing nanobody-based immunotherapeutic strategies to treat myeloproliferative neoplasms driven by mutations of the CALR gene, as well as precising the role and biodistribution of circulating CALR oncoproteins in these diseases. I am using a combination of several approaches, including nanobody production, linking of small molecules/peptides to nanobodies through endopeptidase-mediated reactions and immuno-PET.

Novalla Pishesha, PhD Novalla Pishesha, PhD | Email
PhD in Biological Engineering, Massachusetts Institute of Technology, Cambridge

I am interested in developing protein and cell-based therapeutics to tackle autoimmunity and infectious diseases.

 

Xin Liu, PhD Xin Liu, PhD | Email
PhD in Chemistry, Purdue University, Indiana

My research interests are "targeted imaging and therapeutic agents, influenza research."

Eugene Obeng, PhD Eugene Obeng, PhD | Email
Ph.D in Biochemistry, Biomolecular and Therapeutic Engineering, Monash University, Melbourne, Australia

My research interests include multifunctional targeting tools for elucidating immune and cellular processes. My current research focus seeks to explore multifunctional and multivalent engineering techniques for cellular and molecular medicine development.

Jin Gan, PhD Jin Gan, PhD | Email
Ph.D. in Chemical Biology, Leiden University Medical Center, the Netherland

I am currently working on the development of nanobodies against the Ub-Proteasome System (UPS) and UBLs, and the application of nanobodies to remodel UPS and UBLs. 

 

Pavana Suresh

Pavana Suresh, PhD
PhD in Biochemistry and Structural Biology, Stony Brook University, New York

I am currently working on elucidating the biochemical and structural characteristics of E2 ubiquitin-conjugating enzymes using alpaca-derived nanobodies.

 

Himadri Medhi Himadri Medhi, PhD
PhD in Nanoscience and Technology, University of Hyderabad, India

My research interest focuses on developing different nanobodies, nanomaterial-nanobody conjugations by click chemistry and targeting them to different cells, tissues. I also investigate the biodistribution of these conjugations by PET.

Graduate Students

Lotte Wijne Lotte Wijne | Email
PhD candidate in cell biology, University of Leiden, The Netherlands

I am interested in deciphering the complex roles of E2 enzymes, an important group of enzymes involved in ubiquitin conjugation. Ubiquitination is an important post-translational modification within the cell and plays many key roles in cellular functioning. Having the ability to study and manipulate them with nanobodies will greatly help in our understanding of these enzymes and how they contribute to health and disease.

Elisha Verhaar Elisha Verhaar | Email
PhD Candidate

My interest is in cancer and immunology. Project: using nanobodies to target mutated KRAS in pancreatic cancer.

Alumni

Post-doctoral Fellows

2023 Ryan Alexander, Research Scientist at Takeda
2022 Thibault Harmand, Research Scientist at Cerberus Therapeutics, Cambridge
2022 Nicholas McCaul, Lecturer, University of Huddersfield, United Kingdom
2020 Md Ashraful Islam, Research Scientist at Minerva Imaging, Denmark
2020 Ross Cheloha, Investigator, National Institutes of Health, Bethesda
2020 Andrew Woodham, Senior Research Scientist, BioNTech, Cambridge
2019 Tao Fang, Senior Research Scientist
2019 Mohammad Rashidian, Assistant Professor, Dana-Farber Cancer Institute, Boston
2018 Matthias Truttmann, Assistant Professor, University of Michigan Medical School, Ann Arbor

Graduate Students

2019 Djenet Bousbaine, Research Fellow, Stanford University
2019 Jason Nguyen, Patent Agent, Wilson Sonsini Goodrich
2019 Yushu (Joy) Xie, Research Scientist, Bluebird Bio
2018 Ella Zeyang Li, IP Practice Specialist, Jones Day
2018 Jingjing Ling, Research Fellow, Singapore Immunology Network

Other Lab Members

2022 Hailey Heston (Research Associate)
2022 Frederique van den Haak (Research Associate) 
2020 William Pinney (Research Assistant), Fulbright Scholar, Munich, Germany
2020 Stephen Kolifrath (Lab Supervisor), Laboratory Manager, Pandemic Response Lab, New York City
2019 Robert Miller (Lab Manager), retired
2018 Harun Sugito (Research Technician), MD student, Dartmouth College
2018 Rhogerry Deshycka (Research Assistant), PhD student, UCSF