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Principal Investigator

Richard I. Gregory, PhD

Principal Investigator, Gregory Lab

Department of Pediatrics Stem Cell Biology Chair, Professor, Department of Biological Chemistry and Molecular Pharmacology, and Department of Pediatrics, Harvard Medical School, Co-Director, HMS Initiative for RNA Medicine

Postdoctoral Fellows

Esteban Orellana, PhD Esteban Orellana, PhD
esteban.orellana@childrens.harvard.edu

Esteban joined the Gregory Laboratory in May 2018. He completed his graduate studies at Purdue University. His project involved ligand-mediated miRNA delivery and miRNA combinatorial therapeutics for cancer. Esteban's current research focuses on RNA methylation and its role in gene regulation and cancers including glioblastoma and sarcomas.
Xin Yang, PhD Xin Yang, PhD
xin.yang@childrens.harvard.edu

Xin received his PhD in 2018 from Beijing Institute of Genomics, Chinese Academy of Sciences. He studied the topology of mRNA m5C methylomes and the essential roles of m5C in mRNA export regulation. Xin also studied m6A and its role in the dynamic regulation of co-transcriptional R-loop formation and transcription termination. Xin joined the Gregory Lab in September 2019 and started his research on RNA modifications and their roles in gene regulation and cancer.
Julia Ramirez-Moya, PhD

Julia Ramirez-Moya, PhD
julia.ramirezmoya@childrens.harvard.edu

Julia received her PhD in 2021 from "Alberto Sols" Biomedical Research Institute at Madrid, Spain. She studied RNA regulatory mechanisms in cancer, such as miRNA regulation and A-to-I RNA editing. In April 2021 she joined the Gregory lab and her current research focuses on tRNA editing and its role in cancer.
Erdem Sendinc, PhD

Erdem Sendinc, PhD
erdem.sendic@childrens.harvard.edu

After collaborating with the Gregory Lab on various projects, Erdem joined the lab in 2022. He is interested in investigating the roles of RNA modifications in RNA metabolism and cellular biology. He utilizes RNA mass spectrometry to characterize chemical modifications in RNA sequences. His current research focuses on mRNA and tRNA modifying enzymes in the context of regulation of gene expression.

Other Lab Members

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David Nelson
Laboratory Manager
david.nelson@childrens.harvard.edu
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Kaitlin Taylor
Research Assistant
kaitlin.taylor@childrens.harvard.edu

Kaitlin received her Bachelor’s degree in 2022 from High Point University where she worked on a research project involving use of new technologies to advance novel compounds for Neurofibromatosis Type 1. She recently joined the Gregory Lab where she studies tRNA regulation and its role in cancer cells.​

Lab Alumni

Jia Cui
Postdoc (2018-2023)
Current: Scientist, Amgen, Thousand Oaks CA

Jiazhi Li Postdoc (2019-2022)Current: Assistant Professor, Inner Mongolia University, Hohhot, China

Xushen Xiong Postdoc (2019-2022)Current: Assistant Professor, Zhejiang University, Hangzhou, China

Robert LaPierre
Lab Manager (2006-2013)
Current: Physician Assistant, New England Neurological Associates P.C.

Elena Piskounova
Grad Student (2007-2011)
Current: Assistant Professor, Weill-Cornell Medical School

John P. Hagan
Postdoc (2008-2012)
Current: Assistant Professor, University of Texas Health Sciences Center, Houston, TX

Hao-Ming Chang
Postdoc (2008-2012)
Current: Research Scientist, Alexion Pharmaceuticals Inc.

Robinson Triboulet
Postdoc (2008-2018)
Current: Research Scientist, Twentyeight-seven Therapeutics

James Thornton
Grad Student (2009-2013)
Current: Senior Director of Business Development, Codiak BioSciences

Natalia J. Martinez
Postdoc (2009-2013)
Current: Research Scientist, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH)

Masaki Mori
Postdoc (2011-2014)
Current: Associate Professor, Shiga University of Medical Science, Japan

Yoshinori Nishimoto
Postdoc (2013-2016)
Current: Neurologist, Keio University School of Medicine, Japan

Peng Du
Postdoc (2012-2018)
Current: Assistant Professor, Peking University, China

Shuibin Lin
Postdoc (2012-2018)
Current: Assistant Professor, Sun Yat-sen University, China

Junho Choe
Postdoc (2014-2019)
Current: Assistant Professor, Hanyang University, Korea

Carmen Rios
Lab Manager (2013-2020)
Current: Research Operations Manager, Broad Institute of MIT and Harvard

Mehdi Pirouz
Postdoc (2014-2021)
Current: Assistant Professor, Rutgers Medical School and Center for Advanced Biotechnology and Medicine

Qi Liu
Postdoc (2017-2021)
Current: Assistant Professor, Guangdong School of Agricultural Science

Quentin Hahn
Research Assistant (2020-2022)
Current: Graduate Student, UNC Chapel Hill

Elisabeth Siegal
Visiting Graduate Student (2021-2022)
Current: University of Utrecht Medical School