Principal Investigator, Gregory Lab
Department of Pediatrics Stem Cell Biology Chair, Professor, Department of Biological Chemistry and Molecular Pharmacology, and Department of Pediatrics, Harvard Medical School, Co-Director, HMS Initiative for RNA Medicine
Xin Yang, PhD
Xin received his PhD in 2018 from Beijing Institute of Genomics, Chinese Academy of Sciences. He studied the topology of mRNA m5C methylomes and the essential roles of m5C in mRNA export regulation. Xin also studied m6A and its role in the dynamic regulation of co-transcriptional R-loop formation and transcription termination. Xin joined the Gregory Lab in September 2019 and started his research on RNA modifications and their roles in gene regulation and cancer.
Erdem Sendinc, PhD
After collaborating with the Gregory Lab on various projects, Erdem joined the lab in 2022. He is interested in investigating the roles of RNA modifications in RNA metabolism and cellular biology. He utilizes RNA mass spectrometry to characterize chemical modifications in RNA sequences. His current research focuses on mRNA and tRNA modifying enzymes in the context of regulation of gene expression.
Sujin Kim, PhD
Sujin received her PhD in 2023 from Korea Advanced Institute of Science and Technology (KAIST). She studied the role of mitochondrial double-stranded RNAs (mt-dsRNAs) in degenerative diseases, along with the discovery of mt-dsRNAs. In particular, while studying the regulatory mechanism of mt-dsRNA, Sujin learned the role of RNA modification in multiple biological systems and immune responses. She joined the Gregory lab in August 2023 and started her research to understand the roles of RNA modification in various biological contexts including cellular communication.
Boyang Shi, PhD
Boyang received his PhD in 2020 from Beijing Institute of Genomics, Chinese Academy of Sciences. His projects mainly focused on RNA regulatory mechanisms in embryonic development and cancer, such as RNA structure and RNA binding protein phase separation. In July 2023 Boyang joined the Gregory lab and started his research on RNA post-transcriptional regulation and the development of tRNA sequencing methods.
Other Lab Members
Kaitlin received her Bachelor’s degree in 2022 from High Point University where she worked on a research project involving use of new technologies to advance novel compounds for Neurofibromatosis Type 1. She recently joined the Gregory Lab where she studies tRNA regulation and its role in cancer cells.
Current: Assistant Professor, Geisel School of Medicine at Dartmouth
Current: Scientist, Alnylam Pharmaceuticals
Current: Scientist, Amgen, Thousand Oaks CA
Jiazhi LiPostdoc (2019-2022) Current: Assistant Professor, Inner Mongolia University, Hohhot, China
Xushen XiongPostdoc (2019-2022) Current: Assistant Professor, Zhejiang University, Hangzhou, China
Lab Manager (2006-2013)
Current: Physician Assistant, New England Neurological Associates P.C.
Grad Student (2007-2011)
Current: Assistant Professor, Weill-Cornell Medical School
John P. Hagan
Current: Assistant Professor, University of Texas Health Sciences Center, Houston, TX
Current: Research Scientist, Alexion Pharmaceuticals Inc.
Current: Research Scientist, Twentyeight-seven Therapeutics
Grad Student (2009-2013)
Current: Senior Director of Business Development, Codiak BioSciences
Natalia J. Martinez
Current: Research Scientist, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH)
Current: Associate Professor, Shiga University of Medical Science, Japan
Current: Neurologist, Keio University School of Medicine, Japan
Current: Assistant Professor, Peking University, China
Current: Assistant Professor, Sun Yat-sen University, China
Current: Assistant Professor, Hanyang University, Korea
Lab Manager (2013-2020)
Current: Research Operations Manager, Broad Institute of MIT and Harvard
Current: Assistant Professor, Rutgers Medical School and Center for Advanced Biotechnology and Medicine
Current: Assistant Professor, Guangdong School of Agricultural Science
Research Assistant (2020-2022)
Current: Graduate Student, UNC Chapel Hill
Visiting Graduate Student (2021-2022)
Current: University of Utrecht Medical School