Infectious Diseases Research | Overview
Research in the Division of Infectious Diseases includes both basic investigation and clinical research. The bench research in the division has the broad objective of elucidating basic mechanisms of microbial pathogenesis and the related host responses that mediate susceptibility to infection, host injury, and protective immunity. Investigation targets viral, bacterial, fungal, and parasitic pathogens of major significance in community acquired infections in the United States, in infections of immunocompromised hosts, and in global public health. Current projects include:
- pathogen-host signaling in streptococcal infection
- novel strategies for pneumococcal vaccines
- enhancing innate and adaptive immunity in neonates
- regulation of bacterial virulence gene expression
- modeling cholera infection and host responses in Drosophila
- HIV pathogenesis, immune response, and vaccine development
- regulation of morphogenesis in Candida albicans
- molecular approaches to malaria pathogenesis
Clinical research is focused in two broad areas: clinical trials in pediatric HIV and clinical epidemiology/clinical decision-making.
Researchers in the Division of Infectious Diseases hold faculty appointments at Harvard Medical School.
Latest Research in Infectious Diseases:
RESEARCHER | FOCUS AREA |
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Anna Aldovini, MD |
HIV biology |
Thea Brennan-Krohn, MD | |
Sandra Burchett, MD, MS |
Viral infections |
Simon Dove, PhD |
Transcription regulation |
David Dowling, PhD | |
Jeffrey Dvorin, MD, PhD |
Malaria, Parasitology, Tropical Medicine |
Sylvia Fischer, PhD |
Host responses to viral infection and (retro)transposon activity, Small RNA mediated gene regulation |
Lakshmi Ganapathi, MBBS |
Clinical Research in Immunocompromised/Transplant Infectious diseases, HIV/Hepatitis C harm reduction in adolescents |
Courtney Gidengil, MD, MPH |
Pediatric Health Services Research |
Donald Goldmann, MD |
Bacterial Infection |
Robert N. Husson, MD |
Molecular pathogenesis of mycobacterial infection |
Dennis Kim, MD, PhD | Host-microbe interactions, Genetics of innate immunity |
Julia R. Koehler, MD |
Fungus; Candida albicans |
Ofer Levy, MD, PhD |
Innate immunity of the human newborn |
Yingjie Lu, PhD |
vaccine development for infectious disease |
Richard Malley, MD |
Pneumococcal pathogenesis and immunity, vaccine development |
Kristin Moffitt, MD |
Host bacterial pathogen interactions, Bacterial vaccine development |
Mari Nakamura, MD, MPH |
Vaccine health services research, Health information technology |
Gregory Priebe, MD
Gregory Priebe, MD
Gregory Priebe, MD |
Pseudomonas aeruginosa infections |
Seth Rakoff-Nahoum, MD, PhD |
Mechanistic Evolutionary Ecology of Host-associated Microbiomes |
Thomas J. Sandora, MD, MPH |
|
Hospital epidemiology, Hand hygiene, Healthcare-Associated Infections, Infection Prevention & Hospital Epidemiology |
|
Tanvi Sharma, MD, MPH |
Pediatric HIV, Immunocompromised infectious diseases |
Simon van Haren, PhD | Molecular mechanism of vaccine adjuvants, Vaccine Development |
Ana M. Vaughan, MD, MPH |
Hospital epidemiology, Infection Prevention and Control, Healthcare-associated infections, Immunocompromised infectious diseases |
Paula I. Watnick, MD, PhD |
Impact of diarrheal pathogens on host metabolism and development; Vaccines and therapeutics for bacterial infection |
Michael R. Wessels, MD |
Streptococcus infection |
Fan Zhang, PhD |
Vaccine Development; Immune Mechanism of Protection Against Human Pathogens |