Current Environment:

Recent Publications | Overview

  1. Wang, S., Chabonnier, L.M., Noval Rivas, M., Georgiev, P., Li, N., Gerber, G., Bry, L., and Chatila, T.A. 2015. My D88 Adaptor-Dependent Microbial Sensing by Regulatory T Cells Promotes Mucosal Tolerance and Enforces Commensalism. Immunity 43:289-303.
  2. Rivas, M.N., Koh, Y.T., Chen, A., Nguyen, A., Lee, Y.H., Lawson, G., and Chatila, T.A. 2012. My D88 is critically involved in immune tolerance breakdown at environmental interfeaces of Foxp3-deficient mice. J clin Invest 122:1933-1947.
  3. Noval Rivas, M., Burton, O.T., Wise, P., Charbonnier, L.M., Georgiev, P., Oettgen, H.C., Rachid, R., and Chatila, T.A. 2015. Regulatory T Cell Reprogramming toward a Th2-Cell-like Lineage Impairs Oral Tolerance and Promotes Food Allergy. Immunity 42:512-523.
  4. Burton, O.T., Noval Rivas, M., Zhou, J.S., Logsdon, S.L., Darling, A.R., Koleoglou, K.J., Roers, A., Houshyar, H., Crackower, M.A., Chatila, T.A., et al. 2014. Immunoglobulin E signal inhibition during allergen ingestion leads to reversal of established food allergy and induction of regulatory T cells. Immunity 41:141-151.
  5. Massoud, A., Charbonnier, L.-M., Lopez, D., Pellegrini, M., Phipatanakul, W., and Chatila, T.A. 2016. An asthma-associated IL4R polymorphism exacerbates airway inflammation by promoting conversion of regulatory T cells to TH17-like cells. Nature Medicine (in press).
  6. Charbonnier, L.M., Wang, S., Georgiev, P., Sefik, E., and Chatila, T.A. 2015. Control of peripheral tolerance by regulatory T cell-intrinsic Notch signaling. Nat Immunol 16:1162-1173.
  7. Xia, M., Viera-Hutchins, L., Garcia-Lloret, M., Noval Rivas, M., Wise, P., McGhee, S.A., Chatila, Z.K., Daher, N., Sioutas, C., and Chatila, T.A. 2015. Vehicular exhaust particles promote allergic airway inflammation through an aryl hydrocarbon receptor-notch signaling cascade. J Allergy Clin Immunol 136:441-453.
  8. Charbonnier, L.M., Janssen, E., Chou, J., Ohsumi, T.K., Keles, S., Hsu, J.T., Massaad, M.J., Garcia-Lloret, M., Hanna-Wakim, R., Dbaibo, G., et al. 2015. Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA. J Allergy Clin Immunol