Basic Research | Overview
The Rao Laboratory seeks to understand how the intrinsic nerve circuits of the gastrointestinal tract normally regulate digestive health, and how dysfunction in these circuits leads to digestive disease.
The Hansen Laboratory studies the role of Ras-like GTP-binding proteins in epithelial morphogenesis and oncogenic transformation.
The Kagan Laboratory is focused on understanding the regulation of innate immunity at the level of microbial detection and signal transduction. Of particular interest is the family of Toll-like receptors (TLRs), which evolved to specifically link microbial detection to the control of adaptive immunity.
The Lencer Laboratory and four NIH-funded core laboratories form a consortium of scientists focused on gastrointestinal research.
The Snapper Laboratory is part of a larger consortium of talented interdisciplinary investigators that focuses on gastrointestinal research.
The Zanoni Laboratory seeks to understand the events that initiate protective immunity in response to infection and tissue injury, or that drive the development of immune-mediated diseases
The Chinnapen Laboratory focuses on both the development of novel technologies to deliver biologic drugs across cellular membrane barriers, and to better understand the cellular mechanisms that underpin this transcellular transport.