Stem Cell Program

Stem Cell Program | Research

The physician-scientists and researchers at Boston Children’s Hospital believe that stem cell biology holds the key to treatments for a wide range of currently untreatable or incurable diseases. Much of our current work centers on specific diseases and the ways in which stem cells might be used to model and understand those diseases. Critical work is also underway to explore how the power and nature of stem cells might be harnessed in the development of general and patient-specific therapies.

To achieve this, we are intensively exploring all pathways available — including embryonic stem cells, induced pluripotent cells (iPS cells) and adult stem cells. By engaging on multiple fronts, we increase our ability and potential to unlock the door to treatments for many diseases. Already, clinical trials are underway on a drug discovered by the Zon Lab that has the potential to boost production of blood stem cells, with significant implications for the treatment of patients with leukemia. The Daley Lab has created more than 20 disease-specific iPS cell lines that will enable researchers to track the origins of a specific disease and to attempt to change its course. Many other exciting investigations are underway and are discussed in these pages.

Our team of scientists are exploring ways to understand and treat blood, neurological, kidney, lung and heart disease; cancer and diabetes; disorders of the muscular and immune systems; and congenital and genetic disorders. Every day brings the potential for new insights, new discoveries, and new hope that the vast promise of stem cells can be realized, and that people suffering from these diseases — both children and adults — can be cured. We are committed to the realization of that goal.

Pluripotent stem cell research

The Stem Cell Program at Boston Children's is pursuing several approaches to creating pluripotent stem cells.

 

Adult stem cell research

Boston Children's Hospital has achieved a number of milestones in adult stem cell research.

 

LEARN MORE 

Explore our research

Blood Disorders and Stem Cells

 
READ MORE
A closeup of a microscope

Cancer

 
READ MORE
a circle showing possible treatments available from the research at Boston Children

Congenital and Genetic Disorders

 
READ MORE
A machine pipes liquid into test tubes.

Diabetes

READ MORE
A closeup of a test tube with a purple cap.

Heart Disease

 
READ MORE
An image of a DNA strand with an image of an intestine.

Intestinal Disorders

READ MORE
Pink liquid being piped into a tray of test tubes.

Kidney Disease

READ MORE

Lung Disease

READ MORE
A microscopic cellular image of bacteria

Liver Disease

READ MORE
Two scientists working in a lab together.

Muscular Disorders

 
READ MORE
A scientist in gown, mask and cap examines a test tube.

Neurologic Disorders

 
READ MORE
The commitment and compassion with which we care for all children and families is matched only by the pioneering spirit of discovery and innovation that drives us to think differently, to find answers, and to build a better tomorrow for children everywhere.

Kevin B. Churchwell, President and CEO

Connect with Boston Children's Hospital