Wayne Tworetzky, MD
Director, Fetal Cardiology Program; Benderson Chair, Boston Children's Hospital; Senior Associate Cardiologist, Department of Cardiology
Associate Professor of Pediatrics, Harvard Medical School
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Wayne Tworetzky, MD
Director, Fetal Cardiology Program; Benderson Chair, Boston Children's Hospital; Senior Associate Cardiologist, Department of Cardiology
Associate Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
University of Stellen Bosch
1985
Stellenbosch
South Africa
Internship
Groote Schuur Hospital
1989
Cape Town
South Africa
Residency
Groote Schuur Hospital
1993
Cape Town
South Africa
Residency
UC San Francisco
1995
San Francisco
CA
Fellowship
UC San Francisco
1999
San Francisco
CA
Certifications
American Board of Pediatrics (Cardiology)
Publications
Maternal Vascular Malperfusion and Anatomic Cord Abnormalities Are Prevalent in Pregnancies With Fetal Congenital Heart Disease. View Abstract
Severe Features of Systemic Juvenile Idiopathic Arthritis in Patients With Congenital Heart Disease. View Abstract
Transforming congenital heart disease management: Advances in fetal cardiac interventions. View Abstract
Technical Success and Serious Adverse Events for Fetal Aortic Valvuloplasty in a Large 20-Year Cohort. View Abstract
High prevalence of left superior vena cava and congenital heart disease in patients with pre- and postnatally diagnosed esophageal atresia/tracheoesophageal fistula. View Abstract
Associations Between Maternal Sociodemographics and Hospital Mortality in Newborns With Prenatally Diagnosed Hypoplastic Left Heart Syndrome. View Abstract
Knowledge is power: regarding SMFM Consult Series #64: Systemic lupus erythematosus in pregnancy. View Abstract
Transuterine Ultrasound-Guided Fetal Embolization of Vein of Galen Malformation, Eliminating Postnatal Pathophysiology. View Abstract
Implications of United States Supreme Court's ruling on Dobbs vs Jackson Women's Health Organization: perspective of physicians caring for critically ill fetuses and newborns. View Abstract
Early Experience With Reverse Double Switch Operation for the Borderline Left Heart. View Abstract
Technically successful fetal aortic valvuloplasty acutely improves left heart output. View Abstract
Impact of maternal social vulnerability and timing of prenatal care on outcome of prenatally detected congenital heart disease. View Abstract
Hemodynamic and anatomic changes after fetal aortic valvuloplasty are associated with procedural success and postnatal biventricular circulation. View Abstract
Percutaneous transuterine fetal cerebral embolisation to treat vein of Galen malformations at risk of urgent neonatal decompensation: study protocol for a clinical trial of safety and feasibility. View Abstract
Fetal Brain Volume Predicts Neurodevelopment in Congenital Heart Disease. View Abstract
Contemporary Outcomes in Tetralogy of Fallot With Absent Pulmonary Valve After Fetal Diagnosis. View Abstract
Impact of Socioeconomic Status, Race and Ethnicity, and Geography on Prenatal Detection of Hypoplastic Left Heart Syndrome and Transposition of the Great Arteries. View Abstract
Late gestation predictors of a postnatal biventricular circulation after fetal aortic valvuloplasty. View Abstract
Extracardiac Doppler indices predict perinatal mortality in fetuses with Ebstein anomaly and tricuspid valve dysplasia. View Abstract
Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly). View Abstract
Regional Brain Growth Trajectories in Fetuses with Congenital Heart Disease. View Abstract
Risk Factors for Mortality and Circulatory Outcome Among Neonates Prenatally Diagnosed With Ebstein Anomaly or Tricuspid Valve Dysplasia: A Multicenter Study. View Abstract
Association of Isolated Congenital Heart Disease with Fetal Brain Maturation. View Abstract
1.5-Ventricle Repair Using Left Ventricle as the Subpulmonary Ventricle. View Abstract
Low prenatal detection rate of valvar pulmonary stenosis: What are we missing? View Abstract
Fetal Aortic Valvuloplasty for Evolving Hypoplastic Left Heart Syndrome: A Decision Analysis. View Abstract
Low mortality in fetal supraventricular tachycardia: Outcomes in a 30-year single-institution experience. View Abstract
Fetal cardiac interventions: Where do we stand? View Abstract
Predictors of index admission mortality and morbidity in contemporary esophageal atresia patients. View Abstract
Cerebrovascular blood flow in patients with tetralogy of fallot: prediction for early surgical intervention. View Abstract
Early-Emerging Sulcal Patterns Are Atypical in Fetuses with Congenital Heart Disease. View Abstract
Echocardiographic predictors of neonatal illness severity in fetuses with critical left heart obstruction with intact or restrictive atrial septum. View Abstract
Improved technical success, postnatal outcome and refined predictors of outcome for fetal aortic valvuloplasty. View Abstract
Clinical and Hemodynamic Results After Conversion from Single to Biventricular Circulation After Fetal Aortic Stenosis Intervention. View Abstract
Early hemodynamic changes after fetal aortic stenosis valvuloplasty predict biventricular circulation at birth. View Abstract
Myocardial injury in fetal aortic stenosis: Insights from amniotic fluid analysis. View Abstract
Fetal interventions for structural heart disease. View Abstract
Cardiac output and blood flow redistribution in fetuses with D-loop transposition of the great arteries and intact ventricular septum: insights into pathophysiology. View Abstract
The boundaries of fetal cardiac intervention: Expand or tighten? View Abstract
Right Atrial Dysfunction in the Fetus with Severely Regurgitant Tricuspid Valve Disease: A Potential Source of Cardiovascular Compromise. View Abstract
Sonographic Pulmonary Abnormalities in Fetuses With Hypoplastic Left Heart Syndrome and Intact Atrial Septum Undergoing Attempted Atrial Septostomy In Utero. View Abstract
Neurodevelopmental Outcome in Children after Fetal Cardiac Intervention for Aortic Stenosis with Evolving Hypoplastic Left Heart Syndrome. View Abstract
Umbilical Venous Catheter Malposition Is Associated with Necrotizing Enterocolitis in Premature Infants. View Abstract
The Fetus with Ectopia Cordis: Experience and Expectations from Two Centers. View Abstract
Assessment of Progressive Pathophysiology After Early Prenatal Diagnosis of the Ebstein Anomaly or Tricuspid Valve Dysplasia. View Abstract
Assessment of the Melody valve in the mitral position in young children by echocardiography. View Abstract
Detection and successful treatment of emergent anti-SSA-mediated fetal atrioventricular block. View Abstract
WITHDRAWN: Detection and successful treatment of emergent anti-SSA mediated fetal atrioventricular block. View Abstract
Cardiac Findings in the Fetus with Cerebral Arteriovenous Malformation Are Associated with Adverse Outcome. View Abstract
Fetal interventions for congenital heart disease. View Abstract
Brain Injury in Neonates with Complex Congenital Heart Disease: What Is the Predictive Value of MRI in the Fetal Period? View Abstract
International Fetal Cardiac Intervention Registry: A Worldwide Collaborative Description and Preliminary Outcomes. View Abstract
Outcomes and Predictors of Perinatal Mortality in Fetuses With Ebstein Anomaly or Tricuspid Valve Dysplasia in the Current Era: A Multicenter Study. View Abstract
Left Ventricular Remodeling and Function in Children with Biventricular Circulation After Fetal Aortic Valvuloplasty. View Abstract
Prenatal diagnosis of transposition of the great arteries over a 20-year period: improved but imperfect. View Abstract
Perinatal outcome after prenatal diagnosis of single-ventricle cardiac defects. View Abstract
Low rate of prenatal diagnosis among neonates with critical aortic stenosis: insight into the natural history in utero. View Abstract
Fetal aortic valvuloplasty for evolving hypoplastic left heart syndrome: postnatal outcomes of the first 100 patients. View Abstract
Percutaneous fetal cardiac interventions for structural heart disease. View Abstract
Perinatal and infant outcomes of prenatal diagnosis of heterotaxy syndrome (asplenia and polysplenia). View Abstract
Diagnosis and treatment of fetal cardiac disease: a scientific statement from the American Heart Association. View Abstract
Left ventricular diastolic function and characteristics in fetal aortic stenosis. View Abstract
Technical challenges of atrial septal stent placement in fetuses with hypoplastic left heart syndrome and intact atrial septum. View Abstract
Perinatal outcome in fetuses with heterotaxy syndrome and atrioventricular block or bradycardia. View Abstract
Ventricular strain in fetuses with aortic stenosis and evolving hypoplastic left heart syndrome before and after prenatal aortic valvuloplasty. View Abstract
Biventricular conversion after single ventricle palliation in patients with small left heart structures: short-term outcomes. View Abstract
Midgestation fetal pulmonary annulus size is predictive of outcome in tetralogy of fallot. View Abstract
Staged left ventricular recruitment after single-ventricle palliation in patients with borderline left heart hypoplasia. View Abstract
Delayed cortical development in fetuses with complex congenital heart disease. View Abstract
Left ventricular function and geometry in fetuses with severe tricuspid regurgitation. View Abstract
Hypoplastic left heart syndrome: current considerations and expectations. View Abstract
Ebstein's malformation of the tricuspid valve: short-term outcomes of the "cone procedure" versus conventional surgery. View Abstract
Circumferential and longitudinal ventricular strain in the normal human fetus. View Abstract
Postnatal left ventricular diastolic function after fetal aortic valvuloplasty. View Abstract
Early reintervention on the pulmonary arteries and right ventricular outflow tract after neonatal or early infant repair of truncus arteriosus using homograft conduits. View Abstract
2010 Report from the ISPD Special Interest Group fetal therapy: fetal cardiac interventions. View Abstract
Aortic stenosis and severe mitral regurgitation in the fetus resulting in giant left atrium and hydrops: pathophysiology, outcomes, and preliminary experience with pre-natal cardiac intervention. View Abstract
The Fetus as a Cardiac Patient: Assessment and Therapy of Cardiovascular Pathology before Birth. View Abstract
Assessment of left ventricular endocardial fibroelastosis in fetuses with aortic stenosis and evolving hypoplastic left heart syndrome. View Abstract
Validation of 3D echocardiographic assessment of left ventricular volumes, mass, and ejection fraction in neonates and infants with congenital heart disease: a comparison study with cardiac MRI. View Abstract
Current status of fetal cardiac intervention. View Abstract
Significance and outcome of left heart hypoplasia in fetal congenital diaphragmatic hernia. View Abstract
Fetal diagnosis of interrupted aortic arch. View Abstract
Cerebral blood flow characteristics and biometry in fetuses undergoing prenatal intervention for aortic stenosis with evolving hypoplastic left heart syndrome. View Abstract
Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopy. View Abstract
Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. View Abstract
Postnatal angiographic appearance of left ventricular myocardium in fetal patients with aortic stenosis having in-utero aortic valvuloplasty. View Abstract
Primary left ventricular rehabilitation is effective in maintaining two-ventricle physiology in the borderline left heart. View Abstract
Predictors of technical success and postnatal biventricular outcome after in utero aortic valvuloplasty for aortic stenosis with evolving hypoplastic left heart syndrome. View Abstract
In utero valvuloplasty for pulmonary atresia with hypoplastic right ventricle: techniques and outcomes. View Abstract
Association of socioeconomic position and medical insurance with fetal diagnosis of critical congenital heart disease. View Abstract
Cardiac anomalies in the fetus. View Abstract
Truncus arteriosus: diagnostic accuracy, outcomes, and impact of prenatal diagnosis. View Abstract
Results of in utero atrial septoplasty in fetuses with hypoplastic left heart syndrome. View Abstract
A vision for an International Society for Fetal and Perinatal Cardiovascular Disease. View Abstract
Outcome of fetuses and infants with double inlet single left ventricle. View Abstract
Matrix-array 3-dimensional echocardiographic assessment of volumes, mass, and ejection fraction in young pediatric patients with a functional single ventricle: a comparison study with cardiac magnetic resonance. View Abstract
Fast block flow tracking of atrial septal defects in 4D echocardiography. View Abstract
Changes in left heart hemodynamics after technically successful in-utero aortic valvuloplasty. View Abstract
Pathophysiology, management, and outcomes of fetal hemodynamic instability during prenatal cardiac intervention. View Abstract
Hypoplastic left heart syndrome with intact or highly restrictive atrial septum: surgical experience from a single center. View Abstract
Outcome after prenatal diagnosis of tricuspid atresia: a multicenter experience. View Abstract
Fetal tricuspid valve size and growth as predictors of outcome in pulmonary atresia with intact ventricular septum. View Abstract
Factors affecting technical success of fetal aortic valve dilation. View Abstract
Fetal aortic valve stenosis and the evolution of hypoplastic left heart syndrome: patient selection for fetal intervention. View Abstract
Usefulness of magnetic resonance imaging of left ventricular endocardial fibroelastosis in infants after fetal intervention for aortic valve stenosis. View Abstract
In-utero intervention for hypoplastic left heart syndrome--a perinatologist's perspective. View Abstract
Aortic valvuloplasty in the fetus: technical characteristics of successful balloon dilation. View Abstract
Improving outcomes in fetuses and neonates with congenital displacement (Ebstein's malformation) or dysplasia of the tricuspid valve. View Abstract
Fetal interventions for cardiac defects. View Abstract
Balloon dilation of severe aortic stenosis in the fetus: potential for prevention of hypoplastic left heart syndrome: candidate selection, technique, and results of successful intervention. View Abstract
Creation of an atrial septal defect in utero for fetuses with hypoplastic left heart syndrome and intact or highly restrictive atrial septum. View Abstract
Pulmonary venous pathway obstruction from recurrent restriction at atrial septum late after Fontan procedure. View Abstract
Balloon valvuloplasty for congenital heart disease in the fetus. View Abstract
Association between cardiac tumors and tuberous sclerosis in the fetus and neonate. View Abstract
Effects of losartan in patients with a systemically functioning morphologic right ventricle after atrial repair of transposition of the great arteries. View Abstract
Improved surgical outcome after fetal diagnosis of hypoplastic left heart syndrome. View Abstract
Inhaled nitric oxide in neonates with persistent pulmonary hypertension. View Abstract
Balloon arterioplasty of recurrent coarctation after the modified Norwood procedure in infants. View Abstract
Incidence and implications of systemic to pulmonary collaterals after bidirectional cavopulmonary anastomosis. View Abstract
Pulmonary blood flow alters nitric oxide production in patients undergoing device closure of atrial septal defects. View Abstract
Issues and outcomes in the management of supravalvar aortic stenosis. View Abstract
Congenital obstructive lesions of the right aortic arch. View Abstract
Multiple ventricular septal defects: how and when should they be repaired? View Abstract
Echocardiographic diagnosis alone for the complete repair of major congenital heart defects. View Abstract
Early and late results after repair of aortopulmonary septal defect and associated anomalies in infants <6 months of age. View Abstract
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