Tina Young Poussaint, MD, FACR
Radiologist-in-Chief; Lionel W. Young Chair in Radiology
Professor of Radiology, Harvard Medical School
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Tina Young Poussaint, MD, FACR
Radiologist-in-Chief; Lionel W. Young Chair in Radiology
Professor of Radiology, Harvard Medical School
Medical Services
Languages
English
Certifications
American Board of Radiology (Diagnostic Radiology)
American Board of Radiology (Neuroradiology)
Professional History
Tina Young Poussaint, MD, FACR is Radiologist-in-Chief, the Lionel W. Young Chair in Radiology at Boston Children’s Hospital and Professor of Radiology at Harvard Medical School. She received her Bachelor of Arts degree from Mount Holyoke College (magna cum laude) where she was elected to the Phi Beta Kappa Society. She received her MD with honors from Yale University School of Medicine where she was elected to the Alpha Omega Alpha Honor Medical Society. After an internship in pediatrics at Yale-New Haven Hospital (YNHH), she completed residency training in diagnostic radiology and a fellowship in neuroradiology at Massachusetts General Hospital (MGH). After serving on the neuroradiology faculty at MGH, she then joined the faculty at Boston Children’s Hospital. Dr. Poussaint is board-certified in Diagnostic Radiology with a Certificate of Added Qualification in Neuroradiology.
Dr. Poussaint is a Fellow of the American College of Radiology (ACR) and has served in several professional organizations including the ASNR, RSNA and SPR. She is a Past-President and Gold Medal Recipient of the American Society of Pediatric Neuroradiology (ASPNR). She is Past-President of the American Society of Neuroradiology. Dr. Poussaint is Principal Investigator of the Pediatric Brain Tumor Consortium Neuroimaging Center.
Approach to Care
I have been inspired by my patients and their families during my career. In particular, my research has focused on the effective care of children through characterization of direct or surrogate imaging markers to improve understanding of physiologic and metabolic profiles of pediatric brain tumors at diagnosis and after therapy.
During college, 2 medicine career exploration projects stimulated me to pursue medicine as my life work. A career in medicine includes my love of science and dedication to helping people. Patient care, teaching and research remain the hallmark of my career.
During college, 2 medicine career exploration projects stimulated me to pursue medicine as my life work. A career in medicine includes my love of science and dedication to helping people. Patient care, teaching and research remain the hallmark of my career.
Publications
Post-radiation MR imaging features in Molecular and Mutational Analyses in Pontine Pediatric Diffuse Midline Gliomas. View Abstract
Multimodal deep learning improves recurrence risk prediction in pediatric low-grade gliomas. View Abstract
Alzheimer Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for Monitoring of Amyloid-Related Imaging Abnormalities. View Abstract
Cortically Based Brain Tumors in Children: A Decision-Tree Approach in the Radiology Reading Room. View Abstract
A foundation model for generalized brain MRI analysis. View Abstract
An international study presenting a federated learning AI platform for pediatric brain tumors. View Abstract
Stepwise Transfer Learning for Expert-level Pediatric Brain Tumor MRI Segmentation in a Limited Data Scenario. View Abstract
Longitudinal risk prediction for pediatric glioma with temporal deep learning. View Abstract
The Brain Tumor Segmentation (BraTS) Challenge 2023: Focus on Pediatrics (CBTN-CONNECT-DIPGR-ASNR-MICCAI BraTS-PEDs). View Abstract
Noninvasive Molecular Subtyping of Pediatric Low-Grade Glioma with Self-Supervised Transfer Learning. View Abstract
Noninvasive molecular subtyping of pediatric low-grade glioma with self-supervised transfer learning. View Abstract
Automated temporalis muscle quantification and growth charts for children through adulthood. View Abstract
Review of imaging recommendations from Response Assessment in Pediatric Neuro-Oncology (RAPNO). View Abstract
Expert-level pediatric brain tumor segmentation in a limited data scenario with stepwise transfer learning. View Abstract
Neurological and Psychological Sequelae Associated With Multisystem Inflammatory Syndrome in Children. View Abstract
Correlation between Multiparametric MR Imaging and Molecular Genetics in Pontine Pediatric High-Grade Glioma. View Abstract
Complications of Cancer Therapy in Children: A Comprehensive Review of Neuroimaging Findings. View Abstract
Complications of Cancer Therapy in Children: A Comprehensive Review of Neuroimaging Findings. View Abstract
Summary of the 2022 ACR Intersociety Meeting. View Abstract
Harnessing imaging tools to guide immunotherapy trials: summary from the National Cancer Institute Cancer Imaging Steering Committee workshop. View Abstract
Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020. View Abstract
Imaging of pediatric spine and spinal cord tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee/ASPNR White Paper. View Abstract
Imaging of pediatric brain tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee/ASPNR White Paper. View Abstract
Reply. View Abstract
Amyloid-Related Imaging Abnormalities with Emerging Alzheimer Disease Therapeutics: Detection and Reporting Recommendations for Clinical Practice. View Abstract
Corrigendum to: LTBK-01. Updates On The Phase Ii And Re-treatment Study Of AZD6244 (Selumetinib) For Children With Recurrent Or Refractory Pediatric Low Grade Glioma: A Pediatric Brain Tumor Consortium (PBTC) Study. View Abstract
Response assessment in paediatric intracranial ependymoma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. View Abstract
The 2021 World Health Organization Classification of Tumors of the Central Nervous System: What Neuroradiologists Need to Know. View Abstract
MRI Radiogenomics of Pediatric Medulloblastoma: A Multicenter Study. View Abstract
ADC Histogram Analysis of Pediatric Low-Grade Glioma Treated with Selumetinib: A Report from the Pediatric Brain Tumor Consortium. View Abstract
Deep learning-based automatic tumor burden assessment of pediatric high-grade gliomas, medulloblastomas, and other leptomeningeal seeding tumors. View Abstract
Multisystem Inflammatory-like Syndrome in a Child Following COVID-19 mRNA Vaccination. View Abstract
Corrigendum to: Deep learning-based automatic tumor burden assessment of pediatric high-grade gliomas, medulloblastomas, and other leptomeningeal seeding tumors. View Abstract
Machine Assist for Pediatric Posterior Fossa Tumor Diagnosis: A Multinational Study. View Abstract
A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study. View Abstract
Neurologic Involvement in Children and Adolescents Hospitalized in the United States for COVID-19 or Multisystem Inflammatory Syndrome. View Abstract
A Phase I and Surgical Study of Ribociclib and Everolimus in Children with Recurrent or Refractory Malignant Brain Tumors: A Pediatric Brain Tumor Consortium Study. View Abstract
A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042). View Abstract
Phase II study of peginterferon alpha-2b for patients with unresectable or recurrent craniopharyngiomas: a Pediatric Brain Tumor Consortium report. View Abstract
Deep Learning for Pediatric Posterior Fossa Tumor Detection and Classification: A Multi-Institutional Study. View Abstract
A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study. View Abstract
Response assessment in paediatric high-grade glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group. View Abstract
MR Imaging Correlates for Molecular and Mutational Analyses in Children with Diffuse Intrinsic Pontine Glioma. View Abstract
Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium. View Abstract
Brainstem Injury in Pediatric Patients Receiving Posterior Fossa Photon Radiation. View Abstract
Primary Neoplasms of the Pediatric Brain. View Abstract
Lionel W. Young, MD. View Abstract
Lionel W. Young, MD, FACR (1932-2019). View Abstract
Indications and Imaging Modality of Choice in Pediatric Headache. View Abstract
Quantifying radiation therapy response using apparent diffusion coefficient (ADC) parametric mapping of pediatric diffuse intrinsic pontine glioma: a report from the pediatric brain tumor consortium. View Abstract
Use of a Qualification Phantom for PET Brain Imaging in a Multicenter Consortium: A Collaboration Between the Pediatric Brain Tumor Consortium and the SNMMI Clinical Trials Network. View Abstract
National Cancer Institute Workshop on Proton Therapy for Children: Considerations Regarding Brainstem Injury. View Abstract
Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology committee. View Abstract
Response to Harreld re: "Response assessment in medulloblastoma and leptomeningeal seeding tumors: recommendations from the Response Assessment in Pediatric Neuro-Oncology Committee". View Abstract
Multiparametric Analysis of Permeability and ADC Histogram Metrics for Classification of Pediatric Brain Tumors by Tumor Grade. View Abstract
A pediatric brain tumor consortium phase II trial of capecitabine rapidly disintegrating tablets with concomitant radiation therapy in children with newly diagnosed diffuse intrinsic pontine gliomas. View Abstract
Correlation of 18F-FDG PET and MRI Apparent Diffusion Coefficient Histogram Metrics with Survival in Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium. View Abstract
Automated Processing of Dynamic Contrast-Enhanced MRI: Correlation of Advanced Pharmacokinetic Metrics with Tumor Grade in Pediatric Brain Tumors. View Abstract
A molecular biology and phase II study of imetelstat (GRN163L) in children with recurrent or refractory central nervous system malignancies: a pediatric brain tumor consortium study. View Abstract
Apparent diffusion coefficient histogram metrics correlate with survival in diffuse intrinsic pontine glioma: a report from the Pediatric Brain Tumor Consortium. View Abstract
Introduction to 'Advances in Pediatric Neuroradiology'. View Abstract
Pediatric brain tumors. View Abstract
A phase I trial and PK study of cediranib (AZD2171), an orally bioavailable pan-VEGFR inhibitor, in children with recurrent or refractory primary CNS tumors. View Abstract
Pediatric brain tumor consortium multisite assessment of apparent diffusion coefficient z-axis variation assessed with an ice-water phantom. View Abstract
18F-FDG PET and MR imaging associations across a spectrum of pediatric brain tumors: a report from the pediatric brain tumor consortium. View Abstract
Diversity in diagnostic radiology. View Abstract
Infantile postoperative encephalopathy: perioperative factors as a cause for concern. View Abstract
Efficacy of bevacizumab plus irinotecan in children with recurrent low-grade gliomas--a Pediatric Brain Tumor Consortium study. View Abstract
Recommendations for imaging tumor response in neurofibromatosis clinical trials. View Abstract
Bevacizumab (BVZ)-associated toxicities in children with recurrent central nervous system tumors treated with BVZ and irinotecan (CPT-11): a Pediatric Brain Tumor Consortium Study (PBTC-022). View Abstract
Exploratory evaluation of MR permeability with 18F-FDG PET mapping in pediatric brain tumors: a report from the Pediatric Brain Tumor Consortium. View Abstract
Pediatric brain tumors. View Abstract
Challenges with defining response to antitumor agents in pediatric neuro-oncology: a report from the response assessment in pediatric neuro-oncology (RAPNO) working group. View Abstract
Callosal dysgenesis in fetuses with ventriculomegaly: levels of agreement between imaging modalities and postnatal outcome. View Abstract
A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study. View Abstract
Imaging tumors of the pediatric central nervous system. View Abstract
Ultrasound and MRI of fetuses with ventriculomegaly: can cortical development be used to predict postnatal outcome? View Abstract
Magnetic resonance volumetric assessments of brains in fetuses with ventriculomegaly correlated to outcomes. View Abstract
Phase II trial of tipifarnib and radiation in children with newly diagnosed diffuse intrinsic pontine gliomas. View Abstract
MRI as a central component of clinical trials analysis in brainstem glioma: a report from the Pediatric Brain Tumor Consortium (PBTC). View Abstract
A phase II study of gefitinib and irradiation in children with newly diagnosed brainstem gliomas: a report from the Pediatric Brain Tumor Consortium. View Abstract
Evaluation of 18F-FDG PET and MRI associations in pediatric diffuse intrinsic brain stem glioma: a report from the Pediatric Brain Tumor Consortium. View Abstract
Outcome of fetuses with cerebral ventriculomegaly and septum pellucidum leaflet abnormalities. View Abstract
DTI assessment of the brainstem white matter tracts in pediatric BSG before and after therapy: a report from the Pediatric Brain Tumor Consortium. View Abstract
Frequency and cause of disagreements in imaging diagnosis in children with ventriculomegaly diagnosed prenatally. View Abstract
Variability in PET quantitation within a multicenter consortium. View Abstract
Neurodevelopmental outcome of fetuses referred for ventriculomegaly. View Abstract
Resolution of cerebral artery stenosis in a child with sickle cell anemia treated with hydroxyurea. View Abstract
Imaging of back pain in children. View Abstract
Phase I study of SU5416, a small molecule inhibitor of the vascular endothelial growth factor receptor (VEGFR) in refractory pediatric central nervous system tumors. View Abstract
Meningioangiomatosis associated with meningioma: a case report. View Abstract
Establishment and results of a magnetic resonance quality assurance program for the pediatric brain tumor consortium. View Abstract
Frequency and cause of disagreements in diagnoses for fetuses referred for ventriculomegaly. View Abstract
Exploratory evaluation of two-dimensional and three-dimensional methods of FDG PET quantification in pediatric anaplastic astrocytoma: a report from the Pediatric Brain Tumor Consortium (PBTC). View Abstract
Phase I trial of tipifarnib in children with newly diagnosed intrinsic diffuse brainstem glioma. View Abstract
Phase I clinical trial of cilengitide in children with refractory brain tumors: Pediatric Brain Tumor Consortium Study PBTC-012. View Abstract
Phase I trial of VNP40101M (Cloretazine) in children with recurrent brain tumors: a pediatric brain tumor consortium study. View Abstract
Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report. View Abstract
The Neuroimaging Center of the Pediatric Brain Tumor Consortium-collaborative neuroimaging in pediatric brain tumor research: a work in progress. View Abstract
Changes in cerebral cortex of children treated for medulloblastoma. View Abstract
Predicting survival of children with CNS tumors using proton magnetic resonance spectroscopic imaging biomarkers. View Abstract
Phase I trial of imatinib in children with newly diagnosed brainstem and recurrent malignant gliomas: a Pediatric Brain Tumor Consortium report. View Abstract
Neuroimaging of the child with developmental delay. View Abstract
Evaluation of real-time single-shot fast spin-echo MRI for visualization of the fetal midline corpus callosum and secondary palate. View Abstract
Phase II study of oxaliplatin in children with recurrent or refractory medulloblastoma, supratentorial primitive neuroectodermal tumors, and atypical teratoid rhabdoid tumors: a pediatric brain tumor consortium study. View Abstract
Phase II study of thalidomide and radiation in children with newly diagnosed brain stem gliomas and glioblastoma multiforme. View Abstract
Phase I trial of intrathecal spartaject busulfan in children with neoplastic meningitis: a Pediatric Brain Tumor Consortium Study (PBTC-004). View Abstract
Advanced neuroimaging of pediatric brain tumors: MR diffusion, MR perfusion, and MR spectroscopy. View Abstract
X-linked creatine transporter defect: a report on two unrelated boys with a severe clinical phenotype. View Abstract
Age associated increase in the prevalence of chromosome 22q loss of heterozygosity in histological subsets of benign meningioma. View Abstract
Diencephalic syndrome: a cause of failure to thrive and a model of partial growth hormone resistance. View Abstract
Superficial neurofibroma: a lesion with unique MRI characteristics in patients with neurofibromatosis type 1. View Abstract
MR imaging of abdominopelvic involvement in neurofibromatosis type 1: a review of 43 patients. View Abstract
Perfusion MRI of U87 brain tumors in a mouse model. View Abstract
Neuroimaging findings in neurofibromatosis type 1 and 2. View Abstract
Spectroscopic and perfusion magnetic resonance imaging predictors of progression in pediatric brain tumors. View Abstract
MRI and 1H MRS findings in Smith-Lemli-Opitz syndrome. View Abstract
Chemotherapy for progressive low-grade gliomas in children older than ten years: the Dana-Farber experience. View Abstract
Scoliosis: evidence-based diagnostic evaluation. View Abstract
Interobserver reproducibility of volumetric MR imaging measurements of plexiform neurofibromas. View Abstract
Prediction of adverse outcome with cerebral lactate level and apparent diffusion coefficient in infants with perinatal asphyxia. View Abstract
Imaging of pediatric head trauma. View Abstract
Magnetic resonance of metabolic and degenerative diseases in children. View Abstract
Pediatric Head Trauma View Abstract
MR of Metabolic and Degenerative Disease in Childhood View Abstract
Thallium-201 single-photon emission CT in recurrent squamous cell carcinoma of the head and neck. View Abstract
Magnetic resonance imaging (MRI) is one of the most important imaging modalities in pediatric neuroradiology. View Abstract
Magnetic resonance imaging of pediatric brain tumors: state of the art. View Abstract
Editorial View Abstract
MR Imaging of Pediatric Brain Tumors: State of the Art View Abstract
Congenital Malformations of the Cerebellum and Posterior Fossa: Radiographic Diagnosis and Surgical
Treatment.
View Abstract
Thallum-201 Single-Proton Emission CT versus CT for the Detection of Recurrent Squamous Cell Carcinoma of the Head and Neck View Abstract
Imaging of the Developmentally Delayed Child View Abstract
Magnetic resonance spectroscopy and magnetic resonance imaging findings in Krabbe's disease. View Abstract
Proton magnetic spectroscopic imaging of the child's brain: the response of tumors to treatment. View Abstract
Periventricular nodular heterotopia in patients with filamin-1 gene mutations: neuroimaging findings. View Abstract
Case Report: Supratentorial intraventricular PNET View Abstract
Case Report: Supratentorial ependymoma View Abstract
Role of intraoperative skeletal scintigraphy in the localization of osteoblastomas. View Abstract
Neurological dysfunction associated with postoperative cerebellar mutism. View Abstract
Neuroradiology portion of Pediatric Radiology Chapter
View Abstract
Cervicomedullary astrocytomas of childhood: clinical and imaging follow-up. View Abstract
Occult lumbosacral dysraphism in children and young adults: diagnostic performance of fast screening and conventional MR imaging. View Abstract
Structural anomalies revealed by neuroimaging studies in the brains of patients with neurofibromatosis type 1 and large deletions. View Abstract
Imaging of neuroendocrine disorders of childhood. View Abstract
Neuroimaging of scoliosis in childhood. View Abstract
Scoliosis circa 2000: radiologic imaging perspective. II. Treatment and follow-up. View Abstract
Scoliosis circa 2000: radiologic imaging perspective. I. Diagnosis and pretreatment evaluation. View Abstract
Childhood brain tumor: neuroimaging correlated with disease outcome. View Abstract
Tectal tumors of childhood: clinical and imaging follow-up. View Abstract
Focal cortical dysplasia with glioproliferative changes causing seizures: report of 3 cases. View Abstract
Efficacy of fast screening MR in children and adolescents with suspected intracranial tumors. View Abstract
Diencephalic syndrome: clinical features and imaging findings. View Abstract
Angiographic changes after pial synangiosis in childhood moyamoya disease. View Abstract
Imaging of the spine and spinal cord View Abstract
Structural imaging of CNS tumors View Abstract
Hemorrhagic pituitary adenomas of adolescence. View Abstract
Maternal phenylketonuria: magnetic resonance imaging of the brain in offspring. View Abstract
Structural abnormalities in brain magnetic resonance images of depressed children. View Abstract
Pediatric orbital and visual pathway lesions. View Abstract
Hemorrhagic vasculopathy after treatment of central nervous system neoplasia in childhood: diagnosis and follow-up. View Abstract
MRI abnormalities in major psychiatric disorders: an exploratory comparative study. View Abstract
Brain abscesses caused by Clostridium septicum as a complication of hemolytic-uremic syndrome. View Abstract
Imaging of the pediatric spine and spinal neuraxis View Abstract
Dysraphic myelodysplasias associated with urogenital and anorectal anomalies: prevalence and types seen with MR imaging. View Abstract
Imaging of pediatric central nervous system infections. View Abstract
Imaging of pediatric CNS infections View Abstract
MR quantification of cerebral ventricular volume using a semiautomated algorithm. View Abstract
Anterior communicating artery collateral flow protection against ischemic change during carotid endarterectomy. View Abstract
Cystic retrocerebellar malformations: unification of the Dandy-Walker complex and the Blake's pouch cyst. View Abstract
MR and CT imaging in multiple sclerosis View Abstract
Magnetic resonance imaging of spine.[Book Review] View Abstract
Ferromagnetism and MR imaging: safety of carotid vascular clamps. View Abstract
Modified schema for classifying positive-pressure tympanograms. View Abstract
Malignant melanoma in renal-transplant recipients. View Abstract
Polyethylene glycol in suppositories: carcinogenic? View Abstract
Rasmussen Encephalitis: typical and atypical MRI findings with pathologic correlation View Abstract
Predicting Clinical Outcome in Perinatal Asphyxia by MRI and MRS View Abstract
MR Imaging and MR Spectroscopy Findings in Smith-Lemli-Opitz Syndrome View Abstract
Predicting Clinical Outcome in Infants with Perinatal Asphyxia View Abstract
Choline to N-Acetylaspartate Ratio is Predictive of Pediatric Brain Tumor Progression View Abstract
Predicting Clinical Outcome in Infants with Perinatal Asphyxia View Abstract
MRSI of Antiangiogenesis/Radiation in Pediatric Gliomas View Abstract
Rasmussen Encephalitis: typical and atypical MRI findings with pathologic correlation View Abstract
Comparison of in Vivo proton MRS of pediatric brain tumors with ex vivo Magic Angle Spinning
MRS of intact biopsy tumor samples
View Abstract
Predicting Clinical Outcome in Perinatal Asphyxia by MRI and MRS View Abstract
Comparison of in Vivo proton MRS of pediatric brain tumors with ex vivo Magic Angle Spinning
MRS of intact biopsy tumor samples
View Abstract
MR Imaging and MR Spectroscopy Findings in Smith-Lemli-Opitz Syndrome View Abstract
MRSI of Antiangiogenesis/Radiation in Pediatric Gliomas
View Abstract
Choline to N-Acetylaspartate Ratio is Predictive of Pediatric BrainTumor Progression
View Abstract
Neuroimaging of Pediatric Brain Tumors: Gd-DTPA Enhanced, Hemodynamic and Diffusion MR Imaging Compared to MR Spectroscopic Imaging.
View Abstract