Tanvi S. Sharma, MD, MPH
Clinical Director/Associate Chief, Division of Infectious Diseases; Associate Physician in Pediatrics, Division of Infectious Diseases; Director, Pediatric Infectious Diseases Fellowship Program; Director, Transplant Infectious Disease Service
Assistant Professor of Pediatrics, Harvard Medical School
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Tanvi S. Sharma, MD, MPH
Clinical Director/Associate Chief, Division of Infectious Diseases; Associate Physician in Pediatrics, Division of Infectious Diseases; Director, Pediatric Infectious Diseases Fellowship Program; Director, Transplant Infectious Disease Service
Assistant Professor of Pediatrics, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
University of Miami School of Medicine
1999
Miami
FL
Residency
Pediatrics
University of Miami School of Medicine/Jackson Memorial Medical Center
2002
Miami
FL
Residency
Pediatrics
University of Miami School of Medicine/Jackson Memorial Medical Center
2003
Miami
FL
Fellowship
Pediatric Infectious Diseases and Immunology
University of Miami School of Medicine/Jackson Memorial Medical Center
2005
Miami
FL
Graduate School
MPH
Harvard School of Public Health
2014
Boston
MA
Certifications
American Board of Pediatrics (General)
American Board of Pediatrics (Infectious Diseases)
Professional History
Tanvi S. Sharma, MD, MPH received her medical degree at the University of Miami Miller School of Medicine, and completed general pediatrics residency and pediatric infectious diseases and immunology fellowship at University of Miami/Jackson Memorial Medical Center. Her work in Miami was focused on the care of children with HIV infection and infections in transplant recipients. Dr. Sharma joined the faculty at Boston Children’s Hospital in 2007, and went on to pursue a Master of Public Health degree at Harvard T. H. Chan School of Public Health. Dr. Sharma has a special interest in infections in immunocompromised patients such as those who have undergone solid organ or hematopoietic stem cell transplantation, patients with primary immunodeficiencies, and patients with HIV. In addition, Dr. Sharma serves as the Program Director for the pediatric infectious diseases fellowship program, and is highly committed to developing strong foundations of medical education for residents and fellows.
Approach to Care
I am committed to the care of vulnerable populations of children at high risk for infectious diseases. Boston Children’s Hospital cares for many patients with compromised immune systems, and it is important for me to be able to work collaboratively with their teams to ensure that these individuals receive exceptional care to achieve the best possible outcomes.
Publications
Child Organ Offer Process (cOOPS): Understanding Infectious Risk Assessment and Mitigation Strategies. View Abstract
Postvaccination Immunogenicity Among Pediatric Solid Organ Transplant Recipients. View Abstract
Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network. View Abstract
Coccidioidomycosis Transmission Through Solid Organ Transplantation (2013-2022): A Report of the Organ Procurement and Transplantation Network ad hoc Disease Transmission Advisory Committee. View Abstract
Infectious Morbidity and All-cause Mortality of Infants HIV-exposed Uninfected Compared to Infants HIV-unexposed Uninfected in Botswana. View Abstract
Multicenter Analysis of Valganciclovir Prophylaxis in Pediatric Solid Organ Transplant Recipients. View Abstract
Hepatitis B transmission/reactivation associated with Hepatitis B core antibody and Hepatitis C nucleic acid testing positive organs: A report from the Organ Procurement and Transplantation Network Disease Transmission Advisory Committee. View Abstract
Approach to multidrug resistant infections in pediatric transplant recipients. View Abstract
Safety and Immunogenicity of Live Viral Vaccines in a Multicenter Cohort of Pediatric Transplant Recipients. View Abstract
Adjunctive Diagnostic Studies Completed Following Detection of Candidemia in Children: Secondary Analysis of Observed Practice From a Multicenter Cohort Study Conducted by the Pediatric Fungal Network. View Abstract
Body surface area compared to body weight dosing of valganciclovir is associated with increased toxicity in pediatric solid organ transplantation recipients. View Abstract
Monoclonal Antibody Use for Coronavirus Disease 2019 in Pediatric Patients: A Multicenter Retrospective Study. View Abstract
Experience with live attenuated varicella vaccination in pediatric heart transplant recipients: Considering a new path forward. View Abstract
Epidemiology and outcomes of invasive aspergillosis among pediatric immunocompromised patients: A 12-year single-center experience. View Abstract
Comorbidities Associated with Hospitalization and Progression Among Adolescents with Symptomatic Coronavirus Disease 2019. View Abstract
Return to School and COVID-19 Vaccination for Pediatric Solid Organ Transplant Recipients in the United States: Expert Opinion for 2021-2022. View Abstract
Comparative Effectiveness of Echinocandins vs Triazoles or Amphotericin B Formulations as Initial Directed Therapy for Invasive Candidiasis in Children and Adolescents. View Abstract
H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model. View Abstract
Return to School for Pediatric Solid Organ Transplant Recipients in the United States During the Coronavirus Disease 2019 Pandemic: Expert Opinion on Key Considerations and Best Practices. View Abstract
Expanding the Differential in a Global Pandemic. View Abstract
Limiting Vancomycin Exposure in Pediatric Oncology Patients With Febrile Neutropenia May Be Associated With Decreased Vancomycin-Resistant Enterococcus Incidence. View Abstract
Mitochondrial Dysfunction and Insulin Resistance in Pubertal Youth Living with Perinatally Acquired HIV. View Abstract
Assessment of the Clinical Utility of Plasma Metagenomic Next-Generation Sequencing in a Pediatric Hospital Population. View Abstract
Progressive multifocal leukoencephalopathy presenting with acute sensorineural hearing loss in an intestinal transplant recipient. View Abstract
A Primary Care-Based Quality Improvement Initiative to Increase Identification of Pediatric International Travelers. View Abstract
Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort. View Abstract
Advances in vaccinating immunocompromised children. View Abstract
Germline GPR161 Mutations Predispose to Pediatric Medulloblastoma. View Abstract
Impact of standardized protocols for cytomegalovirus disease prevention in pediatric solid organ transplant recipients. View Abstract
YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis. View Abstract
Resolving medulloblastoma cellular architecture by single-cell genomics. View Abstract
Human T-cell lymphotrophic virus in solid-organ transplant recipients: Guidelines from the American society of transplantation infectious diseases community of practice. View Abstract
Second-generation molecular subgrouping of medulloblastoma: an international meta-analysis of Group 3 and Group 4 subtypes. View Abstract
Pediatric post-transplant hepatic kaposi sarcoma due to donor-derived human herpesvirus 8. View Abstract
Clinical Vignettes: Donor-Derived Infections. View Abstract
Clinical Vignettes: Donor-Derived Infections. View Abstract
Clinical Vignettes: Donor-Derived Infections. View Abstract
Clinical Vignettes: Donor-Derived Infections. View Abstract
Clinical Vignettes: Donor-Derived Infections. View Abstract
A 5-Year Prospective Multicenter Evaluation of Influenza Infection in Transplant Recipients. View Abstract
Longitudinal Changes in Body Composition by Dual-energy Radiograph Absorptiometry Among Perinatally HIV-infected and HIV-uninfected Youth: Increased Risk of Adiposity Among HIV-infected Female Youth. View Abstract
Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling. View Abstract
Heterogeneity within the PF-EPN-B ependymoma subgroup. View Abstract
Risk-adapted therapy for young children with medulloblastoma (SJYC07): therapeutic and molecular outcomes from a multicentre, phase 2 trial. View Abstract
Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents. View Abstract
Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis. View Abstract
DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma. View Abstract
H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers. View Abstract
A Prospective, International Cohort Study of Invasive Mold Infections in Children. View Abstract
Yield of fungal surveillance cultures in pediatric hematopoietic stem cell transplant patients: a retrospective analysis and survey of current practice. View Abstract
Short communication: The relationship between mitochondrial dysfunction and insulin resistance in HIV-infected children receiving antiretroviral therapy. View Abstract
Attitudes toward transitioning in youth with perinatally acquired HIV and their family caregivers. View Abstract
Vancomycin Use for Pediatric Clostridium difficile Infection Is Increasing and Associated with Specific Patient Characteristics. View Abstract
Allograft-Transmitted Histoplasma capsulatum Infection in a Solid Organ Transplant Recipient. View Abstract
Effect of titrated parenteral nutrition on body composition after allogeneic hematopoietic stem cell transplantation in children: a double-blind, randomized, multicenter trial. View Abstract
CD8+ T-cell interleukin-7 receptor alpha expression as a potential indicator of disease status in HIV-infected children. View Abstract
Changes in macronutrient intake among HIV-infected children between 1995 and 2004. View Abstract
Accelerated cardiovascular disease and myocardial infarction risk in patients with the human immunodeficiency virus. View Abstract
Cardiometabolic disease in human immunodeficiency virus-infected children. View Abstract