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Robert C. Tasker, MBBS, MD
Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Anaesthesia, Harvard Medical School
Image
Robert C. Tasker, MBBS, MD
Senior Associate in Critical Care Medicine, Department of Anesthesiology, Critical Care and Pain Medicine
Professor of Anaesthesia, Harvard Medical School
Medical Services
Languages
English
Education
Medical School
The Royal London Hospital Medical College
London
England
Residency
Medicine
Royal College of Physicians
London
England
Fellowship
Pediatric Intensive Care
Great Ormond Street Hospital for Children
London
England
Fellowship
Pediatric Clinical Neurophysiology and Neurocritical Care
Great Ormond Street Hospital for Children
London
England
Fellowship
Pediatric Critical Care Medicine
Johns Hopkins Hospital
Baltimore
MD
Publications
Time to treatment in pediatric patients with repeated episodes of status epilepticus. View Abstract
What Is the New Research in Pediatric Acute Respiratory Distress Syndrome Since the 2023 Consensus Conference? View Abstract
What Do We Know About Pediatric Sepsis Scoring Post-Phoenix? View Abstract
Pediatric Critical Care Medicine 2025, Volume 26: A New Era As We Become Fully Digital. View Abstract
Pediatric Critical Care Medicine 2025, Volume 26: A New Era As We Become Fully Digital. View Abstract
Editor's Choice Articles for December. View Abstract
Lack of association of first and second-line medication dosing and progression to refractory status epilepticus in children. View Abstract
Writing for Pediatric Critical Care Medicine : A Checklist When Using Administrative and Clinical Databases for Research. View Abstract
The editor responds. View Abstract
Editor's Choice Articles for September. View Abstract
Editor's Choice Articles for August. View Abstract
Severe obstructive sleep apnea in children with syndromic craniosynostosis: analysis of pulse transit time. View Abstract
25 Years of Pediatric Critical Care Medicine: An Evolving Journal. View Abstract
Editor's Choice Articles for June. View Abstract
Diagnostic Identification of Acute Brain Dysfunction in Pediatric Sepsis and Septic Shock in the Electronic Health Record: A Comparison of Four Definitions in a Reference Dataset. View Abstract
Editor's Choice Articles for May. View Abstract
Writing for Pediatric Critical Care Medicine: Editorials and Commentaries. View Abstract
Editor's Choice Articles for April. View Abstract
Editor's Choice Articles for April. View Abstract
Editor's Choice Articles for March. View Abstract
Editor's Choice Articles for March. View Abstract
Fair Use of Augmented Intelligence and Artificial Intelligence in the Preparation and Review of Submissions to the Society of Critical Care Medicine Journals: Critical Care Medicine, Pediatric Critical Care Medicine, and Critical Care Explorations. View Abstract
Editor's Choice Articles for February. View Abstract
Editor's Choice Articles for February. View Abstract
Fair Use of Augmented Intelligence and Artificial Intelligence in the Preparation and Review of Submissions to the Society of Critical Care Medicine Journals: Critical Care Medicine, Pediatric Critical Care Medicine, and Critical Care Explorations. View Abstract
Editor's Choice Articles for January. View Abstract
Editor's Choice Articles for January. View Abstract
2023 in Review. View Abstract
Editor's Choice Articles for December. View Abstract
Quantitative Detection and Follow-Up of Intracranial Hypertension in Craniosynostosis: An Optical Coherence Tomography Study. View Abstract
Editor's Choice Articles for November. View Abstract
Pediatric and Adult Brain Death/Death by Neurologic Criteria Consensus Guideline. View Abstract
Editor's Choice Articles for October. View Abstract
Writing for Pediatric Critical Care Medicine: Engaging With Citations to References in the Chatbot Generative Pre-Trained Transformer Era. View Abstract
Editor's Choice Articles for September. View Abstract
Editor's Choice Articles for August. View Abstract
What We Know About Intracranial Hypertension in Children With Syndromic Craniosynostosis. View Abstract
Pediatric status epilepticus management by Emergency Medical Services (the pSERG cohort). View Abstract
Editor's Choice Articles for July. View Abstract
The Reviewer Academy of the Society of Critical Care Medicine: Key Principles and Strategic Plan. View Abstract
Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children. View Abstract
Editor's Choice Articles for June. View Abstract
Heart Rate Change as a Potential Digital Biomarker of Brain Death in Critically Ill Children With Acute Catastrophic Brain Injury. View Abstract
Editor's Choice Articles for May. View Abstract
Editor's Choice Articles for April. View Abstract
Editor's Choice Articles for March. View Abstract
Editor's Choice Articles for February. View Abstract
Editor's Choice Articles for January. View Abstract
2022 In Review. View Abstract
Editor's Choice Articles for December. View Abstract
Pharmacokinetic Modeling of Optimized Midazolam and Pentobarbital Dosing Used in Treatment Protocols of Refractory Status Epilepticus. View Abstract
The United Kingdom Paediatric Critical Care Society Study Group: The 20-Year Journey Toward Pragmatic, Randomized Clinical Trials. View Abstract
Editor's Choice Articles for November. View Abstract
Validation of a Computational Phenotype to Identify Acute Brain Dysfunction in Pediatric Sepsis. View Abstract
Editor's Choice Articles for October. View Abstract
Effectiveness of Training Programs for Reducing Adverse Psychological Outcomes in Parents of Children with Acquired Brain Injury: A Systematic Review and Meta-Analysis. View Abstract
Editor's Choice Articles for September. View Abstract
An exploratory assessment of the management of pediatric traumatic brain injury in three centers in Africa. View Abstract
Editor's Choice Articles for August. View Abstract
Writing for PCCM: Instructions for Authors. View Abstract
Editor's Choice Articles for July. View Abstract
A diffusion tensor imaging analysis of white matter microstructures in non-operated craniosynostosis patients. View Abstract
Editor's Choice Articles for June. View Abstract
Editor's Choice Articles for May. View Abstract
The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up. View Abstract
Editor's Choice Articles for April. View Abstract
Rapid Onset of Neuromuscular Paralysis or Weakness. View Abstract
Optic Nerve Sheath Viscoelastic Properties: Re-Examination of Biomechanical Behavior and Clinical Implications. View Abstract
Editor's Choice Articles for March. View Abstract
Editor's Choice Articles for February. View Abstract
Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. View Abstract
Acute Neurologic Dysfunction in Critically Ill Children: The PODIUM Consensus Conference. View Abstract
Editor's Choice Articles for January. View Abstract
Clinical Characteristics and Outcomes of Children with Acute Catastrophic Brain Injury: A 13-Year Retrospective Cohort Study. View Abstract
Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study. View Abstract
Association Between Anticholinergic Drug Burden and Adequacy of Enteral Nutrition in Critically Ill, Mechanically Ventilated Pediatric Patients. View Abstract
2021 in Review. View Abstract
Editor's Choice Articles for December. View Abstract
Editor's Choice Articles for November. View Abstract
Antipsychotic Drug Prescription in Pediatric Intensive Care Units: A 10-Year U.S. Retrospective Database Study. View Abstract
Editor's Choice Articles for October. View Abstract
Editor's Choice Articles for September. View Abstract
Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus. View Abstract
Editor's Choice Articles for August. View Abstract
The Editor Responds. View Abstract
Cerebral cortex maldevelopment in syndromic craniosynostosis. View Abstract
Factors associated with long-term outcomes in pediatric refractory status epilepticus. View Abstract
Editor's Choice Articles for July. View Abstract
Adult Saethre-Chotzen Syndrome: A Unique Abnormal Breathing Pattern. View Abstract
Sporadic and Periodic Interictal Discharges in Critically Ill Children: Seizure Associations and Time to Seizure Identification. View Abstract
Clinical presentation of new onset refractory status epilepticus in children (the pSERG cohort). View Abstract
Editor's Choice Articles for June. View Abstract
Editor's Choice Articles for May. View Abstract
Editor's Choice Articles for May. View Abstract
Editor's Choice Articles for May. View Abstract
PCCM Narratives, Letters, and Correspondence. View Abstract
Editor's Choice Articles for April. View Abstract
Time to Treatment in Pediatric Convulsive Refractory Status Epilepticus: The Weekend Effect. View Abstract
Editor's Choice Articles for March. View Abstract
Writing for PCCM: The 3,000-Word Structured Clinical Research Report. View Abstract
Editor's Choice Articles for February. View Abstract
Pediatric Critical Care Medicine 2021: The Five Rs. View Abstract
Editor's Choice Articles for January. View Abstract
Defining catastrophic brain injury in children leading to coma and disorders of consciousness and the scope of the problem. View Abstract
Editorial: Delirium, coma, and death by neurological criteria. View Abstract
The authors reply. View Abstract
Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019. View Abstract
The authors reply. View Abstract
Brain Death-Moving Beyond Consistency in the Diagnostic Criteria. View Abstract
First-line medication dosing in pediatric refractory status epilepticus. View Abstract
Practice Recommendations for Transcranial Doppler Ultrasonography in Critically Ill Children in the Pediatric Intensive Care Unit: A Multidisciplinary Expert Consensus Statement. View Abstract
Neurobehavioral Complications After Abdominal Organ Transplantation: Considering a Broader Phenotype and Care Plan. View Abstract
Guidelines for the Management of Severe Traumatic Brain Injury: 2020 Update of the Decompressive Craniectomy Recommendations. View Abstract
Fluid management during diabetic ketoacidosis in children: guidelines, consensus, recommendations and clinical judgement. View Abstract
Neurological deficits are present in syndromic craniosynostosis patients with and without tonsillar herniation. View Abstract
EEG features of brain injury during extracorporeal membrane oxygenation in children. View Abstract
Association of guideline publication and delays to treatment in pediatric status epilepticus. View Abstract
Understanding Brain Death. View Abstract
Measuring Central Cholinergic Inhibition As a Risk Factor for Delirium Remains a Challenge. View Abstract
Exposure to Anticholinergic Medications in Pediatric Severe Sepsis and Feasibility of Delirium Screening. View Abstract
Determination of Death by Neurologic Criteria: Paco2 and the Three Phases of the Apnea Test. View Abstract
Cortical Thickness in Crouzon-Pfeiffer Syndrome: Findings in Relation to Primary Cranial Vault Expansion. View Abstract
Incorporating Ethically Relevant Empirical Data From Systematic Review of Reasons: A Case Study of Sudden Unexpected Death in Epilepsy. View Abstract
Hyperoxemia and Death of the Critically Ill: Is There a Problem of Confounding by Indication or Outcome? View Abstract
Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. View Abstract
Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. View Abstract
Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. View Abstract
Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. View Abstract
Traumatic Brain Injury and Pediatric Acute Respiratory Distress Syndrome: Moving the Field Forward. View Abstract
Weighing the Balance of Fluids: Are Pediatric Neurotrauma Patients Different? View Abstract
Dural sinus volume in children with syndromic craniosynostosis and intracranial hypertension. View Abstract
Transcranial Doppler Ultrasound During Critical Illness in Children: Survey of Practices in Pediatric Neurocritical Care Centers. View Abstract
Cerebral blood flow in children with syndromic craniosynostosis: cohort arterial spin labeling studies. View Abstract
Editorial: Brain-related outcomes in vulnerable pediatric populations: an overview and update. View Abstract
Brain-related outcome measures in trials recruiting critically-ill children. View Abstract
The authors reply. View Abstract
Pseudo-Bayesian Model-Based Noninvasive Intracranial Pressure Estimation and Tracking. View Abstract
Improvement in Sleep Architecture is associated with the Indication of Surgery in Syndromic Craniosynostosis. View Abstract
Muscle Weakness After Sepsis in the Critically Ill: Identifiable and Functionally Remediable? View Abstract
Electroencephalographic Reporting for Refractory Status Epilepticus. View Abstract
Brain-related outcome measures in trials recruiting critically-ill children. View Abstract
Fully automated, real-time, calibration-free, continuous noninvasive estimation of intracranial pressure in children. View Abstract
Neurocritical care monitoring of encephalopathic children with acute liver failure: A systematic review. View Abstract
Reliable Glasgow Coma Scale Assessment in Our Sedated and/or Mechanically Ventilated Patients? View Abstract
The onset of pediatric refractory status epilepticus is not distributed uniformly during the day. View Abstract
Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary. View Abstract
Diagnosis of Concussion in the Hospital. View Abstract
Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines. View Abstract
Management of Pediatric Severe Traumatic Brain Injury: 2019 Consensus and Guidelines-Based Algorithm for First and Second Tier Therapies. View Abstract
Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition: Update of the Brain Trauma Foundation Guidelines, Executive Summary. View Abstract
Perioperative Intravenous Fluid in Children Undergoing Brain Tumor Resection: Balancing the Threats to Homeostasis. View Abstract
The authors reply. View Abstract
Author Correction: Neuroimmune disorders of the central nervous system in children in the molecular era. View Abstract
Headache disorders: an update. View Abstract
Meaning of Intracranial Pressure-to-Blood Pressure Fisher-Transformed Pearson Correlation-Derived Optimal Cerebral Perfusion Pressure: Testing Empiric Utility in a Mechanistic Model. View Abstract
Pediatric Neurocritical Care: Evolution of a New Clinical Service in PICUs Across the United States. View Abstract
Anticholinergic Medication Burden in Pediatric Prolonged Critical Illness: A Potentially Modifiable Risk Factor for Delirium. View Abstract
Recommendations on RBC Transfusion in Critically Ill Children With Acute Brain Injury From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. View Abstract
Consensus Recommendations for RBC Transfusion Practice in Critically Ill Children From the Pediatric Critical Care Transfusion and Anemia Expertise Initiative. View Abstract
IV Lidocaine for Status Migraine: Making an "Off-Label" Treatment Decision. View Abstract
"You have to keep your nerve on a DMC." Challenges for Data Monitoring Committees in neonatal intensive care trials: Qualitative accounts from the BRACELET Study. View Abstract
Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers. View Abstract
Traumatic Brain Injury and Infectious Encephalopathy in Children From Four Resource-Limited Settings in Africa. View Abstract
Neuroimmune disorders of the central nervous system in children in the molecular era. View Abstract
Nutrition for term neonates in the paediatric intensive care unit. View Abstract
Factors associated with treatment delays in pediatric refractory convulsive status epilepticus. View Abstract
Pilot study of intracranial venous physiology in craniosynostosis. View Abstract
Association of Time to Treatment With Short-term Outcomes for Pediatric Patients With Refractory Convulsive Status Epilepticus. View Abstract
The authors reply. View Abstract
Estimating the Comparative Effectiveness of Feeding Interventions in the Pediatric Intensive Care Unit: A Demonstration of Longitudinal Targeted Maximum Likelihood Estimation. View Abstract
New-Onset Status Epilepticus in Pediatric Patients: Causes, Characteristics, and Outcomes. View Abstract
Movement disorders: an update. View Abstract
Time to continuous electroencephalogram in repeated admissions to the pediatric intensive care unit. View Abstract
Electrocardiographic variables in children with syndromic craniosynostosis and primary snoring to mild obstructive sleep apnea: significance of identifying respiratory arrhythmia during sleep. View Abstract
Updating Evidence for Using Therapeutic Hypothermia in Pediatric Severe Traumatic Brain Injury. View Abstract
Treatment options for severe traumatic brain injuries in children: current therapies, challenges, and future prospects. View Abstract
Management protocols for status epilepticus in the pediatric emergency room: systematic review article. View Abstract
Continuous EEG in Pediatric Critical Care: Yield and Efficiency of Seizure Detection. View Abstract
Letter to the Editor. Raised intracranial pressure and cognitive delay in craniosynostosis. View Abstract
Regression-based noninvasive estimation of intracranial pressure. View Abstract
Rebuttal From Drs Truog and Tasker. View Abstract
COUNTERPOINT: Should Informed Consent Be Required for Apnea Testing in Patients With Suspected Brain Death? Yes. View Abstract
Differentiating Delirium From Sedative/Hypnotic-Related Iatrogenic Withdrawal Syndrome: Lack of Specificity in Pediatric Critical Care Assessment Tools. View Abstract
Anesthesia and concussion. View Abstract
Patterns of Head Computed Tomography Abnormalities During Pediatric Extracorporeal Membrane Oxygenation and Association With Outcomes. View Abstract
Why Everyone Should Care About "Computable Phenotypes". View Abstract
International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment Study. View Abstract
Updating Evidence for Using Hypothermia in Pediatric Severe Traumatic Brain Injury: Conventional and Bayesian Meta-Analytic Perspectives. View Abstract
Tripartite Stratification of the Glasgow Coma Scale in Children with Severe Traumatic Brain Injury and Mortality: An Analysis from a Multi-Center Comparative Effectiveness Study. View Abstract
Time to electroencephalography is independently associated with outcome in critically ill neonates and children. View Abstract
Are we doing ineffective CPR? View Abstract
Pilot Mechanistic Study of Insulin Modulation of Somatotrophic Hormones, Inflammation, and Lipid Metabolism During Critical Illness in Children. View Abstract
Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition. View Abstract
Refractory status epilepticus in children with and without prior epilepsy or status epilepticus. View Abstract
Developmental behavioral neurology: an update. View Abstract
736: IMPACT OF GLASGOW COMA SCALE SCORE ON MORTALITY IN PEDIATRIC SEVERE TRAUMATIC BRAIN INJURY. View Abstract
Sleep Architecture Linked to Airway Obstruction and Intracranial Hypertension in Children with Syndromic Craniosynostosis. View Abstract
Sepsis kills: suspect it, recognise it and be prompt with treatment. View Abstract
Refractory Status Epilepticus in Children: Intention to Treat With Continuous Infusions of Midazolam and Pentobarbital. View Abstract
Targeted Temperature Management After Cardiac Arrest Due to Drowning: "Frequentist" and "Bayesian" Decision Making. View Abstract
Real-time multi-channel monitoring of burst-suppression using neural network technology during pediatric status epilepticus treatment. View Abstract
Focus on paediatrics. View Abstract
The authors reply. View Abstract
Current Opinion and Use of Transcranial Doppler Ultrasonography in Traumatic Brain Injury in the Pediatric Intensive Care Unit. View Abstract
Analgesia, Sedation, and Intracranial Pressure: Questioning Our Approach in Pediatric Traumatic Brain Injury. View Abstract
Opportunities for Enhancing Patient Recruitment in Clinical Research: Building an Evidence Base for Critical Care Medicine. View Abstract
Critical Care and the Brain. View Abstract
Positioning the breathing but unresponsive patient: what is the evidence? View Abstract
Imaging and serum biomarkers reflecting the functional efficacy of extended erythropoietin treatment in rats following infantile traumatic brain injury. View Abstract
Mechanical Ventilation during Acute Brain-Injury in Children. View Abstract
Dealing with phthalates in medical devices: a case of primum non nocere (first do no harm)? View Abstract
Abnormal transcranial Doppler cerebral blood flow velocity and blood pressure profiles in children with syndromic craniosynostosis and papilledema. View Abstract
Severity-of-Illness Scoring in Pediatric Critical Care: Quo Vadis? View Abstract
Editorial: Pediatric structural cerebrovascular disease, interventions, hemodynamics, and pathophysiology. View Abstract
Focal cerebral ischemia and neurovascular protection: a bench-to-bedside update. View Abstract
Therapeutic Hypothermia in Children. View Abstract
Pediatric Pulseless Arrest With "Nonshockable" Rhythm: Does Faster Time to Epinephrine Improve Outcome? View Abstract
Algorithm for the Management of Intracranial Hypertension in Children with Syndromic Craniosynostosis. View Abstract
Observational study of children admitted to United Kingdom and Republic of Ireland Paediatric Intensive Care Units after out-of-hospital cardiac arrest. View Abstract
Fluid resuscitation of shock in children: what, whence and whither? View Abstract
Another step in understanding glucocorticoid resistance in critical illness. View Abstract
Time from convulsive status epilepticus onset to anticonvulsant administration in children. View Abstract
Status epilepticus in children. View Abstract
Continuous infusion, general anesthesia and other intensive care treatment for uncontrolled status epilepticus. View Abstract
Intracranial pressure and cerebrovascular autoregulation in pediatric critical illness. View Abstract
Prevalence of burnout in pediatric intensivists: an observational comparison with general pediatricians. View Abstract
Intensive care treatment of uncontrolled status epilepticus in children: systematic literature search of midazolam and anesthetic therapies*. View Abstract
Raised intracranial pressure during CNS infection: what should we do about it?*. View Abstract
Death, bereavement and randomised controlled trials (BRACELET): a methodological study of policy and practice in neonatal and paediatric intensive care trials. View Abstract
CT characteristics, risk stratification, and prediction models in traumatic brain injury. View Abstract
Intramuscular midazolam versus intravenous diazepam for treatment of seizures in the pediatric emergency department: a randomized clinical trial. View Abstract
Cerebral edema in children with diabetic ketoacidosis: vasogenic rather than cellular? View Abstract
A trial of hyperglycemic control in pediatric intensive care. View Abstract
Update on pediatric neurocritical care. View Abstract
A clinical and economic evaluation of Control of Hyperglycaemia in Paediatric intensive care (CHiP): a randomised controlled trial. View Abstract
Hypertonic saline therapy for cerebral edema in diabetic ketoacidosis: no change yet, please. View Abstract
Comparison of three different timeframes for pediatric index of mortality data collection in transported intensive care admissions*. View Abstract
Accuracy of a simplified equation for energy expenditure based on bedside volumetric carbon dioxide elimination measurement--a two-center study. View Abstract
Infantile postoperative encephalopathy: perioperative factors as a cause for concern. View Abstract
A randomized trial of hyperglycemic control in pediatric intensive care. View Abstract
Hypothermia did not improve mortality or disability in severe traumatic brain injury. View Abstract
Neuromuscular disorders: from diagnosis to translational research, drug development and clinical trials. View Abstract
Gaps and opportunities in refractory status epilepticus research in children: a multi-center approach by the Pediatric Status Epilepticus Research Group (pSERG). View Abstract
Brain vascular and hydrodynamic physiology. View Abstract
Engineering a control system for hypoglycemia prevention, detection, and intervention in critical care*. View Abstract
Differences in medical therapy goals for children with severe traumatic brain injury-an international study. View Abstract
Nitric oxide avoids the need for a second course of ECMO in congenital diaphragmatic hernia. View Abstract
Glycaemic threshold for activation of the stress response in children. View Abstract
Inhaled adrenaline in acute bronchiolitis. View Abstract
Pediatric neurocritical care: a neurology consultation model and implication for education and training. View Abstract
Tight glucose control (with frequent episodes of hypoglycemia) among children admitted to the pediatric intensive care unit, does not affect neurocognitive development. View Abstract
Pediatric intensive care treatment of uncontrolled status epilepticus. View Abstract
Electroencephalographic seizure activity in the comatose critically ill child: getting closer to knowing what to do. View Abstract
Sport-related concussion: time to take notice. View Abstract
Pediatric critical care, glycemic control, and hypoglycemia: what is the real target? View Abstract
Sleep apnoea in syndromic craniosynostosis occurs independent of hindbrain herniation. View Abstract
Spreading depolarisations and traumatic brain injury: time course and mechanisms. View Abstract
Seizures in 204 comatose children: incidence and outcome. View Abstract
From Lundberg to SIM-ICP: computational physiology and modeling intracranial pressure. View Abstract
Head computed tomography scanning during pediatric neurocritical care: diagnostic yield and the utility of portable studies. View Abstract
Guidelines for the acute medical management of severe traumatic brain injury in infants, children, and adolescents--second edition. View Abstract
Intracranial pressure: influence of head-of-bed elevation, and beyond. View Abstract
Recent advances in autism spectrum disorders. View Abstract
Forgoing life support: how the decision is made in European pediatric intensive care units. View Abstract
Consistency between guidelines and reported practice for reducing the risk of catheter-related infection in British paediatric intensive care units. View Abstract
Prospective operationalization and feasibility of a glycemic control protocol in critically ill children. View Abstract
The microcirculation of the critically ill pediatric patient. View Abstract
Paediatric neurointensive care and decompressive craniectomy for malignant middle cerebral artery infarction. View Abstract
Growing spectrum and relevance of pediatric neuro-immunology. View Abstract
Severe head injury in children: intensive care unit activity and mortality in England and Wales. View Abstract
Outside the limits of normal blood glucose during critical illness: failed homeostasis and quantifying allostatic load. View Abstract
Acute lung injury in children: therapeutic practice and feasibility of international clinical trials. View Abstract
Corpus callosum and inferior forebrain white matter microstructure are related to functional outcome from raised intracranial pressure in child traumatic brain injury. View Abstract
Meningococcal meningitis. View Abstract
Place of death and palliative care following discharge from paediatric intensive care units. View Abstract
The BRACELET Study: surveys of mortality in UK neonatal and paediatric intensive care trials. View Abstract
Pilot evaluation of continuous subcutaneous glucose monitoring in children with multiple organ dysfunction syndrome. View Abstract
Palliative care discharge from paediatric intensive care units in Great Britain. View Abstract
Influenza-associated encephalopathy and neurolgic features of novel influenza A (H1N1) virus infection. View Abstract
Control of hyperglycaemia in paediatric intensive care (CHiP): study protocol. View Abstract
Pediatric neurocritical care: is it time to come of age? View Abstract
Frontal cerebral vulnerability and executive deficits from raised intracranial pressure in child traumatic brain injury. View Abstract
Pediatric neurointensive care: 2008 update for the Rogers' Textbook of Pediatric Intensive Care. View Abstract
Extracorporeal cardiopulmonary resuscitation for in-hospital cardiac arrest: lessons from acute neurotoxicity. View Abstract
Validating serologic biomarkers of brain injury for cardiac arrest research. View Abstract
Blood oxygen on Mount Everest. View Abstract
External validation of the paediatric logistic organ dysfunction score. View Abstract
Pilot safety study of low-dose vasopressin in non-septic critically ill children. View Abstract
Emergency management of children with severe sepsis in the United Kingdom: the results of the Paediatric Intensive Care Society sepsis audit. View Abstract
Brain tissue oxygen tension is more indicative of oxygen diffusion than oxygen delivery and metabolism in patients with traumatic brain injury. View Abstract
Oxygen and living at altitude. View Abstract
Epidemiology of critically ill children in England and Wales: incidence, mortality, deprivation and ethnicity. View Abstract
Neuroendocrine consequences of traumatic brain injury. View Abstract
CPAP and HFOV: different guises of the same underlying intensive care strategy for supporting RSV bronchiolitis. View Abstract
Papilledema in patients with Apert, Crouzon, and Pfeiffer syndrome: prevalence, efficacy of treatment, and risk factors. View Abstract
Prediction of raised intracranial pressure complicating severe traumatic brain injury in children: implications for trial design. View Abstract
Endocrine sequelae of traumatic brain injury in childhood. View Abstract
Ferritin levels in children with severe sepsis and septic shock. View Abstract
Glycemic control and insulin therapy in sepsis and critical illness. View Abstract
Glycemic level in mechanically ventilated children with bronchiolitis. View Abstract
Adrenal response in children with septic shock. View Abstract
Meningococcal disease and meningitis. View Abstract
Traumatic brain injury induced hypothalamic-pituitary dysfunction: a paediatric perspective. View Abstract
Year in review 2006: Critical Care--Paediatrics. View Abstract
Hypopituitarism in childhood and adolescence following traumatic brain injury: the case for prospective endocrine investigation. View Abstract
Biochemical markers of brain injury: Can they point to a diagnosis? View Abstract
Limitation in paediatric logistic organ dysfunction score. View Abstract
Midazolam for refractory status epilepticus in children: higher dosing and more rapid and effective control. View Abstract
Intracranial pressure complicating severe traumatic brain injury in children: monitoring and management. View Abstract
Severe head injury in children: emergency access to neurosurgery in the United Kingdom. View Abstract
Organ donation in paediatric traumatic brain injury. View Abstract
Fluid resuscitation of hypovolemic shock: acute medicine's great triumph for children. View Abstract
Year in review in intensive care medicine, 2005. III. Nutrition, pediatric and neonatal critical care, and experimental. View Abstract
Year in review in intensive care medicine, 2005. II. Infection and sepsis, ventilator-associated pneumonia, ethics, haematology and haemostasis, ICU organisation and scoring, brain injury. View Abstract
A decade of change in regional head injury care: a retrospective review. View Abstract
Standards for head injury management in acute hospitals: evidence from the six million population of the Eastern region. View Abstract
Year in review in intensive care medicine. 2005. I. Acute respiratory failure and acute lung injury, ventilation, hemodynamics, education, renal failure. View Abstract
Changes in white matter late after severe traumatic brain injury in childhood. View Abstract
Staphylococcal sepsis in children. View Abstract
Inter-hospital transport for children and their parent(s). View Abstract
Paediatric cardiac resuscitation: can we do better? View Abstract
Hyperglycemia enhances the cytokine production and oxidative responses to a low but not high dose of endotoxin in rats. View Abstract
Skull x rays, CT scans, and making a decision in head injury. View Abstract
Epidemiology of traumatic brain injury in children receiving intensive care in the UK. View Abstract
Head circumference and brain and hippocampal volume after severe traumatic brain injury in childhood. View Abstract
Hyperventilation in severe diabetic ketoacidosis. View Abstract
Glucose level and risk of mortality in pediatric septic shock. View Abstract
Year in review in intensive care medicine, 2004. III. Outcome, ICU organisation, scoring, quality of life, ethics, psychological problems and communication in the ICU, immunity and hemodynamics during sepsis, pediatric and neonatal critical care, experimental studies. View Abstract
Year in review in intensive care medicine, 2004. II. Brain injury, hemodynamic monitoring and treatment, pulmonary embolism, gastrointestinal tract, and renal failure. View Abstract
Which paediatric head injured patients might benefit from decompression? Thresholds of ICP and CPP in the first six hours. View Abstract
Year in review in intensive care medicine, 2004. I. Respiratory failure, infection, and sepsis. View Abstract
Age-related differences in intracranial pressure and cerebral perfusion pressure in the first 6 hours of monitoring after children's head injury: association with outcome. View Abstract
The neuroendocrine stress response and severity of acute respiratory syncytial virus bronchiolitis in infancy. View Abstract
Violence is not necessary to produce subdural and retinal haemorrhage: a reply to Punt et al. View Abstract
Lymphocyte apoptosis in acute respiratory syncytial virus bronchiolitis. View Abstract
Severe head injury in children: geographical range of an emergency neurosurgical practice. View Abstract
Are anticonvulsants a satisfactory alternative to opiate analgesia in patients experiencing pain with Guillain-Barre syndrome? View Abstract
Year in review in intensive care medicine-2003. Part 3: intensive care unit organization, scoring, quality of life, ethics, neonatal and pediatrics, and experimental. View Abstract
Year in review in intensive care medicine: 2003. II. Brain injury, hemodynamics, gastrointestinal tract, renal failure, metabolism, trauma, and postoperative. View Abstract
Year in review in Intensive Care Medicine-2003. Part 1: Respiratory failure, infection and sepsis. View Abstract
ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents. View Abstract
European Society for Paediatric Endocrinology/Lawson Wilkins Pediatric Endocrine Society consensus statement on diabetic ketoacidosis in children and adolescents. View Abstract
Non-traumatic coma. View Abstract
Hypertonic versus near isotonic crystalloid for fluid resuscitation in critically ill patients. View Abstract
Clinical alert: failure in face of mask seal as a consequence of incorrect face mask assembly. View Abstract
SARS: understanding the coronavirus: apoptosis may explain lymphopenia of SARS. View Abstract
Respiratory viruses in the intensive care unit. View Abstract
Acute laryngotracheobronchitis. View Abstract
Dural haemorrhage in non-traumatic infant deaths: does it explain the bleeding in 'shaken baby syndrome'? View Abstract
Shaken baby syndrome. View Abstract
Interactive effects of high-frequency oscillatory ventilation and inhaled nitric oxide in acute hypoxemic respiratory failure in pediatrics. View Abstract
Does giving albumin infusion in hypoalbuminaeimic children with oncological disease affect colloid osmotic pressure and outcome? View Abstract
Hypertonic versus isotonic crystalloid for fluid resuscitation in critically ill patients. View Abstract
Early severe neutropenia and thrombocytopenia identifies the highest risk cases of severe meningococcal disease. View Abstract
Acute neurology and neurophysiology of haemolytic-uraemic syndrome. View Abstract
Prophylaxis for respiratory syncytial virus infection: missing the target. View Abstract
Neurocritical care and traumatic brain injury. View Abstract
Hippocampal selective regional vulnerability and development. View Abstract
Training and dealing with errors or mistakes in medical practical procedures. View Abstract
Time course of severe respiratory syncytial virus infection in mechanically ventilated infants. View Abstract
Neurological critical care. View Abstract
Gender differences and critical medical illness. View Abstract
Hypercarbia and mild hypothermia, only when not combined, improve postischemic bioenergetic recovery in neonatal rat brain slices. View Abstract
Hypertonic versus isotonic crystalloid for fluid resuscitation in critically ill patients. View Abstract
One hundred courses of high frequency oscillatory ventilation: what have we learned? View Abstract
Reply View Abstract
Persistent pulmonary hypertension of the term neonate: a strategy for management. View Abstract
Pharmacological advance in the treatment of acute brain injury. View Abstract
Nitric oxide ABO blood group difference in children. View Abstract
Multicenter randomized controlled trial of the effects of inhaled nitric oxide therapy on gas exchange in children with acute hypoxemic respiratory failure. View Abstract
Pertussis is increasing in unimmunized infants: is a change in policy needed? View Abstract
Near infrared spectroscopy can detect changes in splanchnic oxygen delivery in neonates during apnoeic episodes. View Abstract
Early postischemic dantrolene-induced amelioration of poly(ADP-ribose) polymerase-related bioenergetic failure in neonatal rat brain slices. View Abstract
Respiratory failure in myasthenia gravis and negative pressure support. View Abstract
Distinct patterns of respiratory difficulty in young children with achondroplasia: a clinical, sleep, and lung function study. View Abstract
Emergency treatment of acute seizures and status epilepticus. View Abstract
Acute hypoxemic respiratory failure in children: case mix and the utility of respiratory severity indices. View Abstract
Combined lung injury, meningitis and cerebral edema: how permissive can hypercapnia be? View Abstract
Timing of recovery of lung function after severe hypoxemic respiratory failure in children. View Abstract
Clinical assessment of acute coma in children. View Abstract
Prolonged mechanical ventilation as a consequence of acute illness. View Abstract
Posteroventral medial pallidotomy in advanced Parkinson's disease. View Abstract
Insulin-dependent diabetes mellitus presenting with ketoalkalosis in Rett syndrome. View Abstract
Early response to inhaled nitric oxide and its relationship to outcome in children with severe hypoxemic respiratory failure. View Abstract
Survey of occupancy of paediatric intensive care units by children who are dependent on ventilators. View Abstract
Protein turnover in critically ill children. View Abstract
Should paediatric intensive care be centralised. View Abstract
Tracheobronchomalacia in preterm infants with chronic lung disease. View Abstract
Extracorporeal support for intractable cardiorespiratory failure due to meningococcal disease. View Abstract
Four patterns of response to inhaled nitric oxide for persistent pulmonary hypertension of the newborn. View Abstract
At the coalface--medical ethics in practice. Futility and death in paediatric medical intensive care. View Abstract
Long-term effects of gastric transposition in children: a physiological study. View Abstract
Extracorporeal membrane oxygenation as a bridge to definitive tracheal surgery in children. View Abstract
Impact of specialised paediatric retrieval teams. A regionally based retrieval service is warranted. View Abstract
Steroids for intubated croup masking airway haemangioma. View Abstract
Bioenergetic recovery following ischemia in brain slices studied by 31P-NMR spectroscopy: differential age effect of depolarization mediated by endogenous nitric oxide. View Abstract
Transfer of critically ill patients with inhaled nitric oxide. View Abstract
Unexpected brainstem compression following routine surgery in a child with oto-palato-digital syndrome. View Abstract
Neurotoxicity of acute glutamate transport blockade depends on coactivation of both NMDA and AMPA/Kainate receptors in organotypic hippocampal cultures. View Abstract
Surfactant adjunctive therapy for Pneumocystis carinii pneumonitis in an infant with acute lymphoblastic leukaemia. View Abstract
Rapid control of severe hypercapnia with high frequency oscillatory ventilation. View Abstract
Failed stereotactic biopsy in a series of 518 cases. View Abstract
Pertussis vaccination: is there a need for a booster dose? View Abstract
Unsuspected Pneumocystis carinii pneumonia and vertically acquired HIV infection in infants requiring intensive care. View Abstract
Delayed protection by MK-801 and tetrodotoxin in a rat organotypic hippocampal culture model of ischemia. View Abstract
Inhaled nitric oxide for pulmonary hypertension after repair of exomphalos. View Abstract
The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed MK-801. View Abstract
Excitatory amino acid neurotoxicity--a broader horizon for cerebral protection? View Abstract
Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures. View Abstract
The clinical significance of seizures in critically ill young infants requiring intensive care. View Abstract
Cerebral intraparenchymal pressure monitoring in non-traumatic coma: clinical evaluation of a new fibreoptic device. View Abstract
Computed tomography in the assessment of raised intracranial pressure in non-traumatic coma. View Abstract
The cerebral function analysing monitor in paediatric medical intensive care: applications and limitations. View Abstract
Intracranial pressure monitoring following hypoxic-ischaemic cerebral insults. View Abstract
EEG monitoring of prolonged thiopentone administration for intractable seizures and status epilepticus in infants and young children. View Abstract
Monitoring in non-traumatic coma. Part I: Invasive intracranial measurements. View Abstract
Monitoring in non-traumatic coma. Part II: Electroencephalography. View Abstract
Oro-facial granulomatosis. Response to elemental diet and provocation by food additives. View Abstract
Absent aortic valve leaflets. View Abstract
Quantitative assessment of muscular hypertonia resulting from cortical lesions in primates. View Abstract
Ipsilateral and focal inhibitory seizures. View Abstract
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