Michael Agus, MD

Division Chief, Division of Medical Critical Care; Endowed Chair in Critical Care; Medical Director, Medical Intensive Care Unit and Intermediate Care Program; Co-Medical Director, Biocontainment Unit

Professor of Pediatrics, Harvard Medical School

Phone 617-355-5849

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NPI 1952382301

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Michael Agus, MD

Division Chief, Division of Medical Critical Care; Endowed Chair in Critical Care; Medical Director, Medical Intensive Care Unit and Intermediate Care Program; Co-Medical Director, Biocontainment Unit

Professor of Pediatrics, Harvard Medical School

Medical Services

Languages

English

Education

Undergraduate School

University of Pennsylvania

1990

Philadelphia

Medical School

University of Pennsylvania School of Medicine

1995

Philadelphia

Internship

Pediatrics

Boston Children's Hospital

1996

Boston

Residency

Pediatrics

Boston Children's Hospital

1998

Boston

Fellowship

Pediatric Critical Care

Massachusetts General Hospital

2002

Boston

Fellowship

Pediatric Endocrinology

Boston Children's Hospital

2002

Boston

Certifications

American Board of Pediatrics (General)

American Board of Pediatrics (Critical Care Medicine)

American Board of Pediatrics (Endocrinology)

Publications

Adjunctive Corticosteroids for Hypotension in the Pediatric Cardiac ICU: Single-Center Retrospective Study, 2020-2021. View Abstract

Comparison of 2-Bag Method With Serial Bag Method for Treatment of Pediatric Diabetic Ketoacidosis. View Abstract

Blood Glucose Range for Hyperglycemic PICU Children With Primary Neurologic Diagnoses: Analysis of the Heart and Lung Failure-Pediatric Insulin Titration (HALF-PINT) Trial. View Abstract

Building global collaborative research networks in paediatric critical care: a roadmap. View Abstract

Serum Phosphorus and Hypophosphatemia During Therapy of Diabetic Ketoacidosis in Children: Single-Center, Retrospective Cohort 2016-2022. View Abstract

The Diabetes Technology Society Error Grid and Trend Accuracy Matrix for Glucose Monitors. View Abstract

The authors reply. View Abstract

Clinical Full-Time Equivalent in PICUs: Survey of the U.S. Pediatric Critical Care Chiefs Network, 2020-2022. View Abstract

Society of Critical Care Medicine Guidelines on Glycemic Control for Critically Ill Children and Adults 2024: Executive Summary. View Abstract

Society of Critical Care Medicine Guidelines on Glycemic Control for Critically Ill Children and Adults 2024. View Abstract

Whole blood transcriptomics identifies subclasses of pediatric septic shock. View Abstract

Running Wide Open: Strong Evidence for Bolus Fluids Selection in Pediatric Sepsis. View Abstract

Whole Blood Transcriptomics Identifies Subclasses of Pediatric Septic Shock. View Abstract

Randomized Trial of Weight-Based Versus Fixed Limit High-Flow Nasal Cannula in Bronchiolitis. View Abstract

Tight Glycemic Control, Inflammation, and the ICU: Evidence for Heterogeneous Treatment Effects in Two Randomized Controlled Trials. View Abstract

Computer clinical decision support that automates personalized clinical care: a challenging but needed healthcare delivery strategy. View Abstract

Utility of plasma beta-hydroxybutyrate to define resolution of diabetic ketoacidosis. View Abstract

Impact of tight glycemic control and hypoglycemia after pediatric cardiac surgery on neurodevelopmental outcomes at three years of age: Findings from a randomized clinical trial. View Abstract

Guidance for Structuring a Pediatric Intermediate Care Unit. View Abstract

A Glycemia Risk Index (GRI) of Hypoglycemia and Hyperglycemia for Continuous Glucose Monitoring Validated by Clinician Ratings. View Abstract

A Multimodal Approach to Training Coronavirus Disease (COVID-19) Processes Across Four Intensive Care Units. View Abstract

Endocrine Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference. View Abstract

Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Contemporary Organ Dysfunction Criteria: Executive Summary. View Abstract

Novel Deployment of Pediatric Biocontainment Unit Nurses in Response to COVID-19. View Abstract

Multicomponent Strategies to Prevent SARS-CoV-2 Transmission - Nine Overnight Youth Summer Camps, United States, June-August 2021. View Abstract

Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions. View Abstract

Performance of an Electronic Decision Support System as a Therapeutic Intervention During a Multicenter PICU Clinical Trial: Heart and Lung Failure-Pediatric Insulin Titration Trial (HALF-PINT). View Abstract

Life-Threatening Hemoptysis in a Pediatric Referral Center. View Abstract

Impact of a Clinical Documentation Integrity Program on Severity of Illness of Expired Patients. View Abstract

Nurses' Perceptions of Workload Burden in Pediatric Critical Care. View Abstract

A Novel Framework Using Remote Telesimulation With Standardized Parents to Improve Research Staff Preparedness for Informed Consent in Pediatric Critical Care Research. View Abstract

Perspective of the Surviving Sepsis Campaign on the Management of Pediatric Sepsis in the Era of Coronavirus Disease 2019. View Abstract

Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with Coronavirus Disease 2019 in New York City. View Abstract

Standardized Protocol Is Associated With a Decrease in Continuous Albuterol Use and Length of Stay in Critical Status Asthmaticus. View Abstract

Corticosteroids probably reduce sepsis-related 28-day mortality in adults - unclear effect in children. View Abstract

Early Enteral Nutrition Is Associated With Improved Clinical Outcomes in Critically Ill Children: A Secondary Analysis of Nutrition Support in the Heart and Lung Failure-Pediatric Insulin Titration Trial. View Abstract

Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. View Abstract

Executive Summary: Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. View Abstract

Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. View Abstract

Executive summary: surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. View Abstract

Long-Term Neurobehavioral and Quality of Life Outcomes of Critically Ill Children after Glycemic Control. View Abstract

Outcomes Associated With Multiple Organ Dysfunction Syndrome in Critically Ill Children With Hyperglycemia. View Abstract

A National Approach to Pediatric Sepsis Surveillance. View Abstract

When Is Our Job Done? Evaluation of Long-Term Psychological Outcomes in Pediatric Critical Care. View Abstract

Executive Summary: Criteria for Critical Care of Infants and Children: PICU Admission, Discharge, and Triage Practice Statement and Levels of Care Guidance. View Abstract

Criteria for Critical Care Infants and Children: PICU Admission, Discharge, and Triage Practice Statement and Levels of Care Guidance. View Abstract

Short-Term Adverse Outcomes Associated With Hypoglycemia in Critically Ill Children. View Abstract

ISPAD Clinical Practice Consensus Guidelines 2018: Diabetic ketoacidosis and the hyperglycemic hyperosmolar state. View Abstract

Adjusting Insulin Delivery to Activity (AIDA) clinical trial: Effects of activity-based insulin profiles on glucose control in children with type 1 diabetes. View Abstract

Glucocorticoid Equipoise. View Abstract

Beyond Survival: Pediatric Critical Care Interventional Trial Outcome Measure Preferences of Families and Healthcare Professionals. View Abstract

The authors reply. View Abstract

Acute Kidney Injury After Pediatric Cardiac Surgery: A Secondary Analysis of the Safe Pediatric Euglycemia After Cardiac Surgery Trial. View Abstract

Tight Glycemic Control in Critically Ill Children. View Abstract

Pediatric intermediate care and pediatric intensive care units: PICU metrics and an analysis of patients that use both. View Abstract

Pediatric Multiple Organ Dysfunction Syndrome: Promising Therapies. View Abstract

Primary Outcome Measures in Pediatric Septic Shock Trials: A Systematic Review. View Abstract

Suspected Cerebral Edema in Diabetic Ketoacidosis: Is There Still a Role for Head CT in Treatment Decisions? View Abstract

Tight Glycemic Control in Critically Ill Children. View Abstract

A Critical Asthma Standardized Clinical and Management Plan Reduces Duration of Critical Asthma Therapy. View Abstract

Design and rationale of Heart and Lung Failure - Pediatric INsulin Titration Trial (HALF-PINT): A randomized clinical trial of tight glycemic control in hyperglycemic critically ill children. View Abstract

Endocrinologic Diseases in Pediatric Cardiac Intensive Care. View Abstract

Tight Glycemic Control in the Pediatric Intensive Care Unit. View Abstract

Impact of Tight Glycemic Control on Neurodevelopmental Outcomes at 1 Year of Age for Children with Congenital Heart Disease: A Randomized Controlled Trial. View Abstract

Pediatric Cardiac Intensive Care Society 2014 Consensus Statement: Pharmacotherapies in Cardiac Critical Care Hormone Replacement Therapy. View Abstract

Triage of Intermediate-Care Patients in Pediatric Hospitals. View Abstract

Practice Patterns in Pediatric Critical Care Medicine: Results of a Workforce Survey. View Abstract

Tight Glycemic Control With Insulin Does Not Affect Skeletal Muscle Degradation During the Early Postoperative Period Following Pediatric Cardiac Surgery. View Abstract

Are preterm newborns who have relative hyperthyrotropinemia at increased risk of brain damage? View Abstract

The relationship between TSH and systemic inflammation in extremely preterm newborns. View Abstract

Tight glycemic control in the ICU - is the earth flat? View Abstract

Tight glycemic control after pediatric cardiac surgery in high-risk patient populations: a secondary analysis of the safe pediatric euglycemia after cardiac surgery trial. View Abstract

The authors reply. View Abstract

Tight glucose control in critically ill children--a systematic review and meta-analysis. View Abstract

Tight glycemic control in children--is the target in sight? View Abstract

Association between Technical Performance Scores and neurodevelopmental outcomes after congenital cardiac surgery. View Abstract

Increasing use of hypertonic saline over mannitol in the treatment of symptomatic cerebral edema in pediatric diabetic ketoacidosis: an 11-year retrospective analysis of mortality*. View Abstract

Measuring and reporting glycemic control in clinical trials: building a path to consensus. View Abstract

Design and rationale of safe pediatric euglycemia after cardiac surgery: a randomized controlled trial of tight glycemic control after pediatric cardiac surgery. View Abstract

Clinical equipoise regarding glycemic control: a survey of pediatric intensivist perceptions. View Abstract

Guidelines for the use of an insulin infusion for the management of hyperglycemia in critically ill patients. View Abstract

Cardiac parameters in children recovered from acute illness as measured by electrical cardiometry and comparisons to the literature. View Abstract

Closed-loop insulin therapy improves glycemic control in children aged <7 years: a randomized controlled trial. View Abstract

Tight glycemic control versus standard care after pediatric cardiac surgery. View Abstract

Value of continuous glucose monitoring for minimizing severe hypoglycemia during tight glycemic control. View Abstract

Non-invasive cardiac output and oxygen delivery measurement in an infant with critical anemia. View Abstract

Clinical utility of Abbott Precision Xceed Pro® ketone meter in diabetic patients. View Abstract

Use of a continuous glucose sensor in an extracorporeal life support circuit. View Abstract

Utility of immediate hemoglobin A1c in children with type I diabetes mellitus. View Abstract

Extreme stress hyperglycemia during acute illness in a pediatric emergency department. View Abstract

Endocrine emergencies View Abstract

Thyroid function in the critically ill newborn and child. View Abstract

Congenital myasthenic syndrome with episodic apnea. View Abstract

Pediatrics: Intensive insulin therapy in critically ill children. View Abstract

Choline acetyltransferase deficiency causing congenital myasthenic syndrome with episodic apnea View Abstract

Critical illness hyperglycemia: is failure of the beta-cell to meet extreme insulin demand indicative of dysfunction? View Abstract

The correlation and level of agreement between end-tidal and blood gas pCO2 in children with respiratory distress: a retrospective analysis. View Abstract

ICU Insulin delivery algorithms: Why so many? How to choose? View Abstract

Intensive Care Unit Insulin Delivery Algorithms: Why So Many? How to Choose? View Abstract

Association between intraoperative and early postoperative glucose levels and adverse outcomes after complex congenital heart surgery. View Abstract

The effect of insulin infusion upon protein metabolism in neonates on extracorporeal life support. View Abstract

Continuous Glucose Monitoring in Pediatric Patients on Extracorporeal Life Support View Abstract

Real-time continuous glucose monitoring in pediatric patients during and after cardiac surgery. View Abstract

Continuous non-invasive end-tidal CO2 monitoring in pediatric inpatients with diabetic ketoacidosis. View Abstract

Adrenal insufficiency in the critically ill neonate and child. View Abstract

Nutritional Support of the Critically Ill Child View Abstract

Continuous glucose monitoring in pediatric cardiac surgery patients View Abstract

Benefits of immediate hemoglobin A1c results in pediatric type 1 diabetes patients View Abstract

Diabetic ketoacidosis in children. View Abstract

The effects of insulin on protein metabolism in critically ill neonates View Abstract

The first use of live continuous glucose monitoring in patients on extracorporeal life support. View Abstract

One step forward: an advance in understanding of adrenal insufficiency in the pediatric critically ill. View Abstract

Endocrine emergencies View Abstract

Clowning in the pediatric intensive care unit View Abstract

The first use of live continuous glucose monitoring in critically ill neonates View Abstract

Continuous non-invasive CO2 monitoring in pediatric inpatients with diabetic ketoacidosis View Abstract

Intravenous insulin decreases protein breakdown in infants on extracorporeal membrane oxygenation. View Abstract

Critically low hormone and catecholamine concentrations in the primed extracorporeal life support circuit. View Abstract

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 38-2003. A 12-year-old girl with fever and coma View Abstract

Intravenous Insulin Improves Protein Breakdown in Infants on Extracorporeal Membrane Oxygenation View Abstract

Technical evaluation of a glucose and oxygen sensor in an extracorporeal circuit View Abstract

Continuous glucose monitoring in an extracorporeal circuit View Abstract

Continuous analyte monitor and method of using same View Abstract

Nutritional support of the critically ill child. View Abstract

Effect of hyperinsulinemic clamp on protein catabolism in critically ill neonates View Abstract

Cardiovascular actions of magnesium. View Abstract

The hormonal response to critical illness View Abstract

Dietary composition and physiologic adaptations to energy restriction. View Abstract

The effect of growth hormone treatment on the insulin-like growth factor axis in a child with nonislet cell tumor hypoglycemia. View Abstract

Non-islet-cell tumor associated with hypoglycemia in a child: successful long-term therapy with growth hormone. View Abstract

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